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1. 发明申请

WO2016100781A1 DRUG DELIVERY DEVICE WITH PROXIMITY SENSOR 审中-公开
标题翻译：具有接近传感器的药物递送装置
公开(公告)号：WO2016100781A1
公开(公告)日：2016-06-23
申请号：PCT/US2015/066597
申请日：2015-12-18
申请人： AMGEN INC.
发明人： MCCULLOUGH, Adam, B.
IPC分类号： A61M5/20 , A61M5/142
CPC分类号： A61M5/14244 , A61M5/00 , A61M5/14248 , A61M5/14526 , A61M5/1454 , A61M5/1684 , A61M5/16881 , A61M5/20 , A61M5/2033 , A61M5/31501 , A61M5/5086 , A61M2005/14252 , A61M2005/1581 , A61M2005/2013 , A61M2005/2073 , A61M2205/13 , A61M2205/33 , A61M2205/3351 , A61M2205/50 , A61M2205/583 , A61M2205/8225
摘要： A drug delivery device, in the form of an injector, may include one of a number of systems for limiting the delivery of a medical fluid or drug product in case of movement of (e.g., removal of) the injector relative to the patient as determined by a proximity sensor. The drug delivery system may in the alternative or in addition include systems for indicating the amount of medical fluid or drug product delivered (or not delivered) in case of movement of (e.g., removal of ) the injector relative to the patient as determined by the proximity sensor. The injector may be, for example, an on-body injector or an hand-held autoinjector.
摘要翻译：在注射器形式下的药物输送装置可以包括许多系统中的一种，用于在所确定的移动（例如，去除）注射器相对于患者的情况下限制医用流体或药物产品的输送通过接近传感器。在替代或附加的情况下，药物递送系统可以包括用于指示在相对于患者的移动（例如，去除）注射器的情况下递送（或未递送）的药物流体或药物产品的量的系统，如由接近传感器注射器可以是例如体内注射器或手持式自动注射器。

2. 发明申请

WO2016100055A1 DRUG DELIVERY DEVICE WITH LIVE BUTTON OR USER INTERFACE FIELD 审中-公开
标题翻译：带有实体按钮或用户界面的药物递送设备
公开(公告)号：WO2016100055A1
公开(公告)日：2016-06-23
申请号：PCT/US2015/064869
申请日：2015-12-10
申请人： AMGEN INC.
发明人： MCCULLOUGH, Adam, B. , GIBSON, Scott, R.
IPC分类号： A61M5/145 , A61M5/32 , A61M5/142
CPC分类号： A61M5/2459 , A61M5/14248 , A61M5/1452 , A61M5/14526 , A61M5/1454 , A61M5/20 , A61M5/2033 , A61M5/2053 , A61M5/28 , A61M5/3158 , A61M5/3202 , A61M5/3243 , A61M2005/206 , A61M2005/208 , A61M2005/2462 , A61M2005/3125 , A61M2205/13 , A61M2205/3306 , A61M2205/3313 , A61M2205/3317 , A61M2205/502 , A61M2205/581 , A61M2205/582 , A61M2205/583 , A61M2205/584 , A61M2205/587
摘要： A drug delivery device includes a container for storing a drug, the container having a stopper for expelling the drug; an injection drive comprising an energy source for directly or indirectly acting on the stopper to expel the drug; a sensor for detecting contact between the drug delivery device and a body of a patient; and a user interface (UI) for activating or causing the activation of the injection drive. The device is operative for drawing attention to the UI, if the sensor detects contact between the drug delivery device and the body of the patient, to thereby indicate that the injection drive is ready to be activated, which activation is the next step in the drug administration process.
摘要翻译：药物输送装置包括用于储存药物的容器，该容器具有用于排出药物的塞子; 注射驱动器，其包括用于直接或间接作用在塞子上以排出药物的能量源; 用于检测药物输送装置与患者身体之间的接触的传感器; 以及用于激活或引起注射驱动器的激活的用户界面（UI）。如果传感器检测到药物输送装置与患者身体之间的接触，从而指示注射驱动器已准备好被激活，则该装置可用于提请注意UI，该活化是药物中的下一步骤管理过程。

3. 发明申请

WO2016091877A1 DRUG DELIVERY DEVICE WITH A DRIVE MECHANISM 审中-公开
标题翻译：具有驱动机构的药物递送装置
公开(公告)号：WO2016091877A1
公开(公告)日：2016-06-16
申请号：PCT/EP2015/078981
申请日：2015-12-08
申请人： SANOFI
发明人： MARSH, William Geoffrey Arthur , MORRIS, Anthony Paul , BAINTON, Mike Cameron , JONES, Matthew Meredith
IPC分类号： A61M5/145 , A61M5/20 , A61M5/31 , A61M5/315
CPC分类号： A61M5/31541 , A61M5/1454 , A61M5/20 , A61M5/2033 , A61M5/2455 , A61M5/3146 , A61M5/31501 , A61M5/31553 , A61M5/31563 , A61M5/3157 , A61M5/31573 , A61M5/31593 , A61M2005/2407 , A61M2005/3126 , A61M2005/31508 , A61M2005/31518 , A61M2205/581 , A61M2205/582 , A61M2205/585
摘要： The present invention relates to a drive mechanism which is suitable for an injection device, especially a drug delivery device. The mechanism comprises a housing (10, 20, 150) having a longitudinal axis defined by a compartment (20) for receiving a cartridge (30), a plunger (122) suitable for acting on a bung (31) of a cartridge (30) retained in the housing (10, 20, 150), a strained pressure spring (140) arranged between the housing (10, 20, 150) and the plunger (122), a retaining member (121) coupled to the plunger (122), and a release member (110) operable between a first state, in which the release member (110) constrains the retaining member (121) to the housing, and a second state, in which the release member (110) is movable relative to the housing (10, 20, 150).
摘要翻译：本发明涉及适用于注射装置，特别是药物输送装置的驱动机构。该机构包括具有由用于容纳盒（30）的隔室（20）限定的纵向轴线的壳体（10,20,150），适于作用在盒（30）的一个（31）上的柱塞）保持在所述壳体（10,20,150）中，布置在所述壳体（10,20,150）和所述柱塞（122）之间的应变压力弹簧（140），联接到所述柱塞（122）的保持构件）和释放构件（110），其在所述释放构件（110）将所述保持构件（121）限制到所述壳体的第一状态和第二状态之间可操作，所述释放构件（110）可移动相对（10,20,150）。

4. 发明申请

WO2015118358A1 SPRING DRIVEN INJECTOR APPARATUS WITH NEEDLE INSERTION 审中-公开
标题翻译：弹簧驱动注射器装置与针插入
公开(公告)号：WO2015118358A1
公开(公告)日：2015-08-13
申请号：PCT/GB2015/050367
申请日：2015-02-10
申请人： OWEN MUMFORD LIMITED
发明人： ANDERSON, Oliver , COWE, Toby , VARDE, Andrew , MARSHALL, Jeremy
IPC分类号： A61M5/20 , A61M5/142 , A61M5/19
CPC分类号： A61M5/3287 , A61M5/14248 , A61M5/1454 , A61M5/19 , A61M5/2033 , A61M5/31578 , A61M5/3202 , A61M5/3298 , A61M5/422 , A61M2005/14252 , A61M2005/14256 , A61M2005/1581 , A61M2005/206 , A61M2005/3289
摘要： An injection device is disclosed which comprises a housing (140, 240, 440, 740) for a plurality of cartridges (110,310,410,810) each containing a medicament to be administered to a patient. A plurality of needles (120, 220, 320, 420, 720, 820) may be provided in communication with the plurality of cartridges. A delivery mechanism is arranged to deliver medicament through the plurality of cartridges via the plurality of needles. An injection device may comprise a drive member (130) having a cam surface (136) configured to engage a surface of a carrier (150) and rotate the carrier about a pivot (152) and at least one plunger (134) arranged to engage a cylinder in the cartridge.
摘要翻译：公开了一种注射装置，其包括用于多个药筒（110,310,410,810）的壳体（140,240,440,740），每个药筒包含要施用于患者的药物。可以提供与多个盒连通的多个针（120,220,320,420,720,820）。递送机构布置成经由多个针将药物输送通过多个药筒。注射装置可以包括具有凸轮表面（136）的驱动构件（130），凸轮表面（136）被配置为接合载体（150）的表面，并使托架围绕枢轴（152）旋转，并且至少一个柱塞（134）布置成接合墨盒中的圆柱体。

5. 发明申请

WO2015063462A2 MEDICAMENT DELIVERY DEVICE 审中-公开
标题翻译：药物输送装置
公开(公告)号：WO2015063462A2
公开(公告)日：2015-05-07
申请号：PCT/GB2014/053193
申请日：2014-10-27
申请人： CONSORT MEDICAL PLC
发明人： WILLOUGHBY, Alastair , HOWARTH, Brad , ANDERSON, Ian , KOPPELMAN, Rachel
IPC分类号： A61M5/145
CPC分类号： A61M5/14526 , A61M5/1454 , A61M5/16877 , A61M5/31515 , A61M2005/14513 , A61M2005/2086 , A61M2205/3334 , A61M2206/22
摘要： A medicament delivery device comprising a first container having a delivery outlet at a front end thereof and a first stopper axially moveable in the first container, the first stopper defining and separating a first chamber and a second chamber in the first container, where the first chamber is axially forwards of the first stopper and the second chamber is axially rearwards of the first stopper. The medicament delivery device further comprising a second container having a second stopper axially moveable in the second container, the second stopper defining and separating a third chamber and a fourth chamber in the second container, where the third chamber is axially forwards of the second stopper and the fourth chamber is axially rearwards of the second stopper, and where the third chamber has a vent outlet in fluid communication with a venting chamber. The first stopper is connected to the second stopper by a tensile member such that axially forwardly movement of the first stopper causes axially forwardly movement of the second stopper due to tensioning of the tensile member. The first stopper is driveable in an axially forwardly direction, the first chamber is configured to contain medicament for delivery through the delivery outlet as the first stopper moves axially forwards, the third chamber contains a viscous fluid that enters the venting chamber via the vent outlet as the second stopper moves axially forwards, and the fourth chamber has a pressure that is substantially equal to or greater than the pressure of the venting chamber. As the first stopper is driven axially forwardly, the tensile member is tensioned and causes the second stopper to move axially forwardly and the venting of viscous fluid into the venting chamber via the vent outlet retards the axially forward movement of the second stopper and the first stopper.
摘要翻译：药物输送装置，其包括第一容器和第二容器，第一容器在其前端具有输送出口，第一限位器可在第一容器中轴向移动，第一限位器限定并分隔第一腔室和第二腔室，第一容器，其中第一腔室在第一止动件的轴向前方，并且第二腔室在第一止动件的轴向后方。所述药物输送装置还包括第二容器，所述第二容器具有可在所述第二容器中轴向移动的第二止动件，所述第二止动件限定并分离所述第二容器中的第三腔室和第四腔室，其中所述第三腔室在所述第二止动件的轴向前方以及第四腔室在第二止动件的轴向后方，并且第三腔室具有与排气室流体连通的排气出口。第一止动件通过拉伸构件连接至第二止动件，使得第一止动件的轴向向前运动由于张力构件的张紧而引起第二止动件的轴向向前运动。第一止动件可沿轴向向前方向驱动，第一腔室构造成容纳用于当第一止动件向前轴向移动时通过输送出口输送的药物，第三腔室容纳经由通气出口进入通气腔室的粘性流体，如第二塞子轴向向前移动，并且第四腔室具有基本上等于或大于通气室的压力的压力。当第一挡块被轴向向前驱动时，拉伸构件被张紧并且使得第二挡块轴向向前移动，并且粘性流体经由排气出口排出到排气室中阻止第二挡块和第一挡块的轴向向前移动

6. 发明申请

WO2014116998A2 FLUID RESTRICTION MECHANISMS FOR DRUG DELIVERY PUMPS 审中-公开
标题翻译：用于药物输送泵的流体限制机构
公开(公告)号：WO2014116998A2
公开(公告)日：2014-07-31
申请号：PCT/US2014/013019
申请日：2014-01-24
申请人： UNITRACT SYRINGE PTY LTD , O'CONNOR, Sean M.
发明人： O'CONNOR, Sean M. , HANSON, Ian B. , BENTE IV, Paul F. , CLEMENTE, Matthew J.
IPC分类号： A61M5/14
CPC分类号： A61M5/16813 , A61M5/141 , A61M5/14248 , A61M5/1452 , A61M5/1454 , A61M5/16822 , A61M2205/13
摘要： A replaceable fluid restriction mechanism 500, 1500 includes: an aperture 520A residing adjacent to a fluid pathway connection and configured to permit flow of a drug fluid through the aperture 520A when the fluid pathway connection is open; an entry point 520B of a fluid channel 520C configured such that the flow of drug fluid can travel through aperture 520A to the entry point 520B and through the fluid channel 520C to an exit point 520D; and an outlet aperture 514 of a port 512 through which the flow of drug fluid may travel after exiting the exit point 520D, wherein a fluid conduit 30 is connected to the fluid restriction mechanism at the outlet aperture. A configurable fluid restriction mechanism 500, 1500 includes a plurality of fluid channels 520C, 521C, 522C, 523C, selectable to align with the entry point 520B and an exit point 520D of the fluid restriction mechanism.
摘要翻译：可替换的流体限制机构500,1500包括：邻近流体通路连接并且构造成允许药物流体在流体通路连接打开时通过孔520A流动的孔520A; 流体通道520C的入口点520B被配置为使得药物流体的流动可以通过孔520A行进到入口点520B并且通过流体通道520C行进到出口点520D; 以及端口512的出口孔514，药物流体的流动可以在离开出口点520D之后行进，其中流体导管30在出口孔处连接到流体限制机构。可配置流体限制机构500,1500包括多个流体通道520C，521C，522C，523C，其可选择地与流体限制机构的入口点520B和出口点520D对准。

7. 发明申请

WO2013114221A3 SKIN-ATTACHABLE MINIATURE DRUG INJECTION DEVICE WITH REMOTE ACTIVATION CAPABILITY AND DRY DRUG CARRIER WITHIN INJECTION NEEDLE 审中-公开
标题翻译：具有远程激活能力的皮肤可连接微型药物注射装置和注射针内的干细胞载体
公开(公告)号：WO2013114221A3
公开(公告)日：2014-07-31
申请号：PCT/IB2013000659
申请日：2013-01-30
申请人： PRECIFLEX SA
发明人： VOUILLAMOZ LUCIEN , ROSEN MELISSA , WALISH JUDY L , YASEVAC DANIEL , BRUEHWILER MICHEL
IPC分类号： A61M5/32 , A61M5/142 , A61M5/145 , A61M5/152 , A61M5/155 , A61M5/158 , A61M5/20 , A61M5/30 , A61M5/31 , A61M5/315
CPC分类号： A61M5/172 , A61B17/3496 , A61B2017/00132 , A61B2017/00212 , A61M5/14248 , A61M5/1454 , A61M5/152 , A61M5/155 , A61M5/2033 , A61M5/2053 , A61M5/2066 , A61M5/31531 , A61M5/3202 , A61M5/3234 , A61M5/326 , A61M5/3273 , A61M5/3291 , A61M5/3293 , A61M5/3294 , A61M2005/14252 , A61M2005/14256 , A61M2005/1426 , A61M2005/14268 , A61M2005/14506 , A61M2005/1581 , A61M2005/1583 , A61M2005/1585 , A61M2005/206 , A61M2005/2073 , A61M2005/2086 , A61M2005/3022 , A61M2005/3142 , A61M2205/3561 , A61M2205/3569 , A61M2205/3592 , A61M2205/8218 , A61M2205/8293 , A61M2209/01 , A61M2209/088 , A61M2210/12
摘要： An active agent or drug injecting device (10) includes a main housing (16) containing a trigger mechanism (24) which can be manually activated via release bar (32) or remotely triggered via wireless receiver (70) activating motor (74), and a second housing (80) containing an injection- and needle-assembly (22). The needle (30) encloses a dry carrier (26) having an active agent (12) disposed thereon. The trigger mechanism triggers the injection assembly to propel the needle into the skin (via spring (54)), to inject the active agent into a living organism (either by letting the active agent diffuse out of the needle or by actively flushing it out), and to subsequently retract the needle back into the housing (80) (via spring (64)).
摘要翻译：活性剂或药物注射装置（10）包括容纳可经由释放杆（32）手动启动或通过无线接收器（70）启动马达（74）远程触发的触发机构（24）的主壳体（16）和包含注射和针组件（22）的第二壳体（80）。针（30）包围其上设置有活性剂（12）的干燥载体（26）。触发机构触发注射组件以将针推入皮肤（通过弹簧（54）），以将活性剂注入活生物体中（通过使活性剂从针中扩散或通过主动冲洗出来）并且随后将针回缩回到壳体（80）（通过弹簧（64））。

8. 发明申请

WO2014099404A1 ADHESIVE ASSEMBLIES AND MICRONEEDLE INJECTION APPARATUSES COMPRISING SAME 审中-公开
标题翻译：粘合组件和包含相同的麦克风注射装置
公开(公告)号：WO2014099404A1
公开(公告)日：2014-06-26
申请号：PCT/US2013/073451
申请日：2013-12-06
申请人： 3M INNOVATIVE PROPERTIES COMPANY
发明人： BURTON, Scott, A. , NG, Chin-Yee
IPC分类号： A61M37/00 , A61M25/02 , A61M5/158 , A61M5/142
CPC分类号： A61M37/0015 , A61M5/14248 , A61M5/1454 , A61M2005/1585 , A61M2025/0273 , A61M2037/0023 , A61M2037/003 , A61M2209/088
摘要： Adhesive assemblies and microneedle injection apparatuses comprising same. The apparatus (100) can include a housing (102) having a base and an opening (115) formed in the base; and an applicator comprising a microneedle array (104), the microneedle array comprising a first major surface (111) and microneedles (105). The applicator can be movable between a first position, and a second position in which at least a portion of the microneedle array extends through the opening in the base. The apparatus can further include an adhesive assembly (118), which can be adhered to the base of the housing. The adhesive assembly can include an extension (125) that extends at least partially into the area defined by the opening, such that when the applicator is in the second position, at least a portion of the first major surface of the microneedle array is in contact with the extension of the adhesive assembly.
摘要翻译：粘合剂组合物和包含其的微针注射装置。设备（100）可以包括具有底座和形成在基座中的开口（115）的壳体（102）和包括微针阵列（104）的涂抹器，所述微针阵列包括第一主表面（111）和微针（105）。施用器可以在第一位置和第二位置之间移动，其中微针阵列的至少一部分延伸穿过基座中的开口。该装置还可以包括粘合剂组件（118），其可以粘附到壳体的基部。粘合剂组件可以包括至少部分地延伸到由开口限定的区域中的延伸部（125），使得当施用器处于第二位置时，微针阵列的第一主表面的至少一部分接触随着粘合剂组件的延伸。

9. 发明申请

WO2014052676A1 PORTABLE MEDICINE INJECTION DEVICE AND ANALYTE METERING SYSTEM 审中-公开
标题翻译：便携式药物注射装置和分析仪计量系统
公开(公告)号：WO2014052676A1
公开(公告)日：2014-04-03
申请号：PCT/US2013/062048
申请日：2013-09-26
申请人： GADLIGHT, INC.
发明人： SHAANAN, Gad , GOLDMAN, Marc
IPC分类号： A61M5/28 , A61M5/20
CPC分类号： A61M5/1452 , A61M5/14244 , A61M5/1454 , A61M5/1723 , A61M5/20 , A61M5/24 , A61M5/28 , A61M5/31528 , A61M5/31543 , A61M5/31551 , A61M5/31558 , A61M5/31561 , A61M5/31575 , A61M5/3158 , A61M5/31585 , A61M2005/14506 , A61M2005/2407 , A61M2005/31518 , A61M2205/3584 , A61M2205/3592 , A61M2205/50 , A61M2205/52 , A61M2205/581 , A61M2205/6063 , A61M2230/201 , G06F19/00 , G06F19/3468 , G08B21/02
摘要： Methods, systems, and devices are described for setting a dose of medicine and injecting the medicine. In one aspect, a method to dispense a medicine includes inserting a cartridge containing a medicine into a cartridge holder coupled to a housing of a medicine injection device, positioning a spine component of the device to make contact with the cartridge in the cartridge holder, selecting a dose of the medicine for injection, in which the selecting includes rotating an injection component of the device to a setting corresponding to the selected dose, and linearly advancing the injection component to rotate a drive gear coupled to the injection component to drive the spine component so as to push the end of the cartridge to dispense the medicine in the amount of the selected dose.
摘要翻译：描述了设置药物剂量和注射药物的方法，系统和装置。在一个方面，一种分配药物的方法包括将容纳药物的药筒插入连接到药物注射装置的壳体的药筒保持器中，将装置的脊部件定位成与药筒保持器中的药筒接触，选择用于注射的药物的剂量，其中所述选择包括将所述装置的注射成分旋转到对应于所选择的剂量的设定，以及线性地推进所述注射部件以使与所述注射部件联接的驱动齿轮旋转以驱动所述脊柱部件以便推动药筒的末端以以所选剂量的量分配药物。

10. 发明申请

WO2013153041A2 INFUSION DEVICE 审中-公开
标题翻译：输液装置
公开(公告)号：WO2013153041A2
公开(公告)日：2013-10-17
申请号：PCT/EP2013/057326
申请日：2013-04-08
申请人： CAREBAY EUROPE LTD
发明人： GIAMBATTISTA, Lucio , BENDEK, Antonio
IPC分类号： A61M5/145
CPC分类号： A61M5/1454 , A61M5/14248 , A61M5/1452 , A61M5/14566 , A61M5/158 , A61M2005/14252 , A61M2005/1583 , A61M2005/1585 , A61M2005/31518
摘要： The present invention relates to an infusion device comprising a housing; a compartment inside said housing for positioning a medicament container, an infusion needle arranged to said housing, being connectable to said medicament container for delivering a dose of medicament, a piston plunger arranged in said housing capable of acting on said medicament container for delivering a dose of medicament, mechanical drive means capable of acting on said piston plunger for delivering a dose of medicament. The invention is characterised in that said piston plunger comprises a number of distinct segments being inter-connectable to each other for forming an elongated piston plunger.
摘要翻译：输液装置技术领域本发明涉及一种包括壳体的输液装置; 位于所述壳体内部的用于定位药物容器的隔室，布置在所述壳体上的浸注针，可连接到所述药物容器，用于输送剂量的药剂;布置在所述壳体中的活塞柱塞，其能够作用在所述药物容器上用于递送剂量的药物，能够作用在所述活塞柱塞上以递送一定剂量的药物的机械驱动装置。本发明的特征在于，所述活塞柱塞包括彼此相互连接以形成细长活塞柱塞的多个不同段。

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