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    • 1. 发明申请
    • MEDICAMENT DELIVERY DEVICE
    • 药物输送装置
    • WO2015063462A2
    • 2015-05-07
    • PCT/GB2014/053193
    • 2014-10-27
    • CONSORT MEDICAL PLC
    • WILLOUGHBY, AlastairHOWARTH, BradANDERSON, IanKOPPELMAN, Rachel
    • A61M5/145
    • A61M5/14526A61M5/1454A61M5/16877A61M5/31515A61M2005/14513A61M2005/2086A61M2205/3334A61M2206/22
    • A medicament delivery device comprising a first container having a delivery outlet at a front end thereof and a first stopper axially moveable in the first container, the first stopper defining and separating a first chamber and a second chamber in the first container, where the first chamber is axially forwards of the first stopper and the second chamber is axially rearwards of the first stopper. The medicament delivery device further comprising a second container having a second stopper axially moveable in the second container, the second stopper defining and separating a third chamber and a fourth chamber in the second container, where the third chamber is axially forwards of the second stopper and the fourth chamber is axially rearwards of the second stopper, and where the third chamber has a vent outlet in fluid communication with a venting chamber. The first stopper is connected to the second stopper by a tensile member such that axially forwardly movement of the first stopper causes axially forwardly movement of the second stopper due to tensioning of the tensile member. The first stopper is driveable in an axially forwardly direction, the first chamber is configured to contain medicament for delivery through the delivery outlet as the first stopper moves axially forwards, the third chamber contains a viscous fluid that enters the venting chamber via the vent outlet as the second stopper moves axially forwards, and the fourth chamber has a pressure that is substantially equal to or greater than the pressure of the venting chamber. As the first stopper is driven axially forwardly, the tensile member is tensioned and causes the second stopper to move axially forwardly and the venting of viscous fluid into the venting chamber via the vent outlet retards the axially forward movement of the second stopper and the first stopper.
    • 药物输送装置,其包括第一容器和第二容器,第一容器在其前端具有输送出口,第一限位器可在第一容器中轴向移动,第一限位器限定并分隔第一腔室和第二腔室, 第一容器,其中第一腔室在第一止动件的轴向前方,并且第二腔室在第一止动件的轴向后方。 所述药物输送装置还包括第二容器,所述第二容器具有可在所述第二容器中轴向移动的第二止动件,所述第二止动件限定并分离所述第二容器中的第三腔室和第四腔室,其中所述第三腔室在所述第二止动件的轴向前方以及 第四腔室在第二止动件的轴向后方,并且第三腔室具有与排气室流体连通的排气出口。 第一止动件通过拉伸构件连接至第二止动件,使得第一止动件的轴向向前运动由于张力构件的张紧而引起第二止动件的轴向向前运动。 第一止动件可沿轴向向前方向驱动,第一腔室构造成容纳用于当第一止动件向前轴向移动时通过输送出口输送的药物,第三腔室容纳经由通气出口进入通气腔室的粘性流体,如 第二塞子轴向向前移动,并且第四腔室具有基本上等于或大于通气室的压力的压力。 当第一挡块被轴向向前驱动时,拉伸构件被张紧并且使得第二挡块轴向向前移动,并且粘性流体经由排气出口排出到排气室中阻止第二挡块和第一挡块的轴向向前移动