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1. 发明申请

WO2018075441A1 DRUG DELIVERY 审中-公开
标题翻译：药物交付
公开(公告)号：WO2018075441A1
公开(公告)日：2018-04-26
申请号：PCT/US2017/056871
申请日：2017-10-17
申请人： SUMMIT STREET MEDICAL LLC
发明人： RIOUX, Robert, F. , LAPLACA, Matthew , GRASSO, Brian , BOMES, Matt , BOURNE, George
IPC分类号： A61M5/20
CPC分类号： A61M5/2033 , A61M5/2053 , A61M5/31578 , A61M2005/206 , A61M2202/04 , A61M2209/088
摘要： A wearable drug delivery device has a drug delivery pack housing a syringe with a drug dose and a separate power pack for providing the energy needed to autoinject the dose into the user. A flexible conductor or rigid connector couples the two packs together and transits the energy released from the power pack to the drug delivery pack.
摘要翻译：一种可佩戴的药物输送装置具有容纳具有药物剂量的注射器的药物输送包和单独的动力包，用于提供将剂量自动注射到使用者所需的能量。柔性导体或刚性连接器将两个包装联接在一起，并将从动力包释放的能量传递给药物输送包装。

2. 发明申请

WO2018031891A1 PLUNGER FOR DRUG DELIVERY DEVICE 审中-公开
标题翻译：药物递送装置的插栓
公开(公告)号：WO2018031891A1
公开(公告)日：2018-02-15
申请号：PCT/US2017/046508
申请日：2017-08-11
申请人： INSULET CORPORATION
发明人： NAZZARO, David
IPC分类号： A61M5/24 , A61M5/28 , A61M5/315
CPC分类号： A61M5/31578 , A61M5/145 , A61M5/2429 , A61M5/283 , A61M5/31513 , A61M5/31535 , A61M2005/3109
摘要： Plunger systems for expelling a liquid drug from a drug container within a wearable drug delivery device are provided. A rotation system coupled to a plunger rotates the plunger about a central axis of the plunger to overcome a static friction between the plunger and the drug container. After rotating the plunger, a drive system moves the plunger forward into the drug container to expel the liquid drug for delivery to the patient. A collapsible plunger includes a cavity. A radial torsion spring positioned in the cavity can provide an outward radial force on the collapsible plunger. The cavity enables the collapsible plunger to compress radially when entering and passing through a region of a drug container having a relatively narrower width. The radial torsion spring can radially expand the collapsible plunger when entering and passing through a region of the drug container having a relatively wider width.
摘要翻译：提供了用于从可佩带药物输送装置内的药物容器排出液体药物的柱塞系统。连接到柱塞的旋转系统围绕柱塞的中心轴旋转柱塞以克服柱塞和药物容器之间的静摩擦。在旋转柱塞之后，驱动系统将柱塞向前移动到药物容器中以排出液体药物以递送给患者。可折叠柱塞包括空腔。定位在空腔中的径向扭转弹簧可以在可折叠柱塞上提供向外的径向力。当进入并且通过具有相对较窄宽度的药物容器的区域时，腔能够使可伸缩柱塞径向压缩。径向扭转弹簧在进入和通过具有相对较宽宽度的药物容器的区域时可径向扩张可折叠柱塞。

3. 发明申请

WO2016091960A1 SPACE SAVING DRUG INJECTION DEVICE 审中-公开
标题翻译：节省空间的注射装置
公开(公告)号：WO2016091960A1
公开(公告)日：2016-06-16
申请号：PCT/EP2015/079141
申请日：2015-12-09
申请人： SANOFI
发明人： MORRIS, Anthony Paul , JONES, Matthew Meredith , BROWN, Oliver Benjamin
IPC分类号： A61M5/20 , A61M5/315
CPC分类号： A61M5/31511 , A61M5/20 , A61M5/2033 , A61M5/24 , A61M5/31535 , A61M5/31536 , A61M5/31541 , A61M5/3157 , A61M5/31575 , A61M5/31578 , A61M5/31583 , A61M5/31593 , A61M2005/3126 , A61M2005/31518 , A61M2005/3154 , A61M2205/581 , A61M2205/582 , A61M2205/583
摘要： Drug injection device for setting and dispensing of a dose of a medicament, comprising: an elongated housing (10) accommodating a cartridge (6) filled with the medicament and sealed with a piston (7), a piston rod (130) extending along a first axis (3) and being threadedly or slidingly engaged with the housing (10) to apply a distally directed thrust to the piston (7) of the cartridge (6), a drive member (110) rotationally or threadedly engaged with the piston rod (130) and having a wheel section or geared section (113), a drive sleeve (100) extending along a second axis (4) at a radial distance from the first axis (3) and substantially parallel but slightly inclined with respect to the first axis, the drive sleeve having a geared section (103) to mesh with the wheel section or geared section (113) of the drive member (110), wherein a first radial distance (d1l) between first and second axes (3, 4) at the distal end (100a) of the drive sleeve (100) is larger than a second radial distance (d2) between first and second axes (3, 4) at the proximal end (100b) of the drive sleeve (100), and wherein the cartridge (6) extends along a third axis (3') parallel to the second axis (4) and intersecting the first axis (3), such that the overall geometry of the housing (10) is slightly tapered in order to provide a space saving form factor.
摘要翻译：用于设置和分配药物剂量的药物注射装置，包括：细长的壳体（10），容纳填充有药物的药筒并用活塞（7）密封;活塞杆（130），沿着第一轴线（3）并且与所述壳体（10）螺纹或滑动地接合以向所述筒（6）的活塞（7）施加向远侧的推力;驱动构件（110），其旋转地或与所述活塞杆（130），并且具有轮部分或齿轮部分（113），驱动套筒（100），其沿着第二轴线（4）以距离第一轴线（3）径向距离延伸并且基本上平行但相对于第一轴线驱动套筒具有与驱动构件（110）的轮部分或齿轮部分（113）啮合的齿轮部分（103），其中第一和第二轴线（3,4）之间的第一径向距离（d1l））在驱动套筒（100）的远端（100a）处大于第二径向分布 ce（d2）在驱动套筒（100）的近端（100b）处的第一和第二轴线（3,4）之间，并且其中盒（6）沿着平行于第二轴线的第三轴线（3'）延伸（4）并且与所述第一轴线（3）相交，使得所述壳体（10）的整体几何形状略微变细，以便提供节省空间的外形尺寸。

4. 发明申请

WO2016004452A1 SYRINGE 审中-公开
标题翻译：注射器
公开(公告)号：WO2016004452A1
公开(公告)日：2016-01-14
申请号：PCT/AU2014/001066
申请日：2014-11-21
申请人： POULOS, George
发明人： POULOS, George
IPC分类号： A61M5/315 , A61M5/178 , A61M5/28
CPC分类号： A61M5/31533 , A61J1/065 , A61M5/002 , A61M5/19 , A61M5/28 , A61M5/3129 , A61M5/31511 , A61M5/31578 , A61M5/3205 , A61M5/322 , A61M5/3234 , A61M5/3243 , A61M2005/2073 , A61M2005/3125 , A61M2205/583
摘要： This invention relates to a method of identifying an accurate dosage of medicine in a dosage chamber of a syringe including the steps of providing an accurate dosage of a detailed single dosage medicine for insertion into a dosage chamber of a syringe; identifying the accurate dosage of medicine in the dosage chamber by retaining a notifier of the accurate dosage; securing the notifier with the syringe wherein the accurate dosage of medicine in a dosage chamber of a syringe is shown by the details on the notifier when secured with the syringe and allowing usage of the syringe to dispense the accurate dosage.
摘要翻译：本发明涉及一种在注射器的剂量室中鉴定药物的精确剂量的方法，包括以下步骤：提供精确剂量的详细的单次剂量药物以插入注射器的剂量室中; 通过保留准确剂量的通知器来确定剂量室中药物的准确剂量; 用注射器固定通知者，其中当用注射器固定并允许使用注射器分配精确剂量时，在注射器的剂量室中的药物的精确剂量由通知器上的细节示出。

5. 发明申请

WO2015123577A1 SYRINGE ADAPTER WITH CONCENTRIC RINGS 审中-公开
标题翻译：具有浓缩环的注射器适配器
公开(公告)号：WO2015123577A1
公开(公告)日：2015-08-20
申请号：PCT/US2015/015912
申请日：2015-02-13
申请人： ILLINOIS TOOL WORKS INC.
发明人： JOZWIK, Raymond , LEONHARD, Michael G.
IPC分类号： A61M5/315 , A61M5/145
CPC分类号： A61M5/007 , A61M5/14546 , A61M5/14566 , A61M5/20 , A61M5/3135 , A61M5/31515 , A61M5/31578 , A61M2005/3114 , A61M2005/31588
摘要： An adapter (14) for use with a syringe and a power injector includes an outer ring (1) having a first end configured for passage of an end of a syringe (19) having at least one flange (12). An inner ring (2) is disposed coaxially within the outer ring. The inner ring has a first end including at least one flange slot. A magnet (3) fixed relative to the inner ring such that when the syringe end is disposed in the outer ring and the at least one flange engages the at least one flange slot, rotation of the syringe causes rotation of the inner ring and magnet relative to the outer ring.
摘要翻译：用于注射器和动力注射器的适配器（14）包括外环（1），其具有构造成用于通过具有至少一个凸缘（12）的注射器（19）的端部的第一端。内圈（2）同轴地设置在外圈内。内圈具有包括至少一个凸缘槽的第一端。相对于内圈固定的磁体（3），使得当注射器端部设置在外圈中并且至少一个凸缘接合至少一个凸缘槽时，注射器的旋转引起内环和磁体相对的旋转到外圈。

6. 发明申请

WO2015074983A2 DRUG DELIVERY DEVICE WITH DOSE DELIVERY CLICKER 审中-公开
标题翻译：药量递送设备与药量交付玩具
公开(公告)号：WO2015074983A2
公开(公告)日：2015-05-28
申请号：PCT/EP2014074709
申请日：2014-11-17
申请人： SANOFI AVENTIS DEUTSCHLAND
发明人： BLANCKE STEFAN , TEUCHER AXEL , JUGL MICHAEL , SCHNEIDER CHRISTIANE
IPC分类号： A61M5/315
CPC分类号： A61M5/31551 , A61M5/24 , A61M5/3146 , A61M5/31505 , A61M5/3157 , A61M5/31575 , A61M5/31578 , A61M5/3158 , A61M5/31593 , A61M2005/3104 , A61M2205/581 , A61M2205/582
摘要： A drug delivery device comprises a lead screw (22) having a longitudinal axis, a distal end and a proximal end that is axially movable in a distal direction relative to a mid-body (20), the lead screw (22) including a threaded shaft (33), wherein the lead screw (22) has a keyway (32) positioned parallel to the longitudinal axis and containing a first section of a dose dispensing feedback component (80); the mid-body (20) being designed to prevent rotation of the lead screw (22) with respect to the mid-body (20), where the mid-body (20) contains a second section (81 ) of the dose dispensing feedback component.
摘要翻译：药物输送装置包括具有纵向轴线，远端和近端的导螺杆（22），所述近端可相对于中间体（20）沿远端方向轴向移动，所述导螺杆（22）包括螺纹（33），其中所述导螺杆（22）具有平行于所述纵向轴线定位的键槽（32）并且包含剂量分配反馈部件（80）的第一部分; 所述中间主体20设计成防止所述导螺杆22相对于所述中间主体20旋转，其中所述中间主体20包含所述剂量分配反馈的第二部分81，零件。

7. 发明申请

WO2015074980A1 DRUG DELIVERY DEVICE WITH UNIDIRECTIONAL COUPLING 审中-公开
标题翻译：具有联合耦合的药物递送装置
公开(公告)号：WO2015074980A1
公开(公告)日：2015-05-28
申请号：PCT/EP2014/074705
申请日：2014-11-17
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH
发明人： BLANCKE, Stefan , TEUCHER, Axel
IPC分类号： A61M5/315
CPC分类号： A61M5/31568 , A61M5/31533 , A61M5/31545 , A61M5/31548 , A61M5/31551 , A61M5/31578 , A61M5/31593 , A61M2005/3126
摘要： A drug delivery device (1) is provided comprising a housing (4), a lead screw (22) that is rotatably fixed with respect to the housing (4) during dose setting and during dose delivery and that is axially moveable in a delivery direction relative to the housing (4) for dose delivery, a number sleeve (23) threadedly engaged with the housing (4) to be screwable relative to the housing (4), and a dial link (25a) which is axially moveable and rotatable with respect to the housing (4) for dose setting and which is prevented from rotation with respect to the housing (4) for dose delivery. The dial link (25) is rotatably fixed with the number sleeve (23) when the dial link (25a) and the number sleeve (24) are in a first arrangement, and the number sleeve (24) and the dial link (25a) are rotatable with respect to one another when the dial link (25) and the number sleeve (24) are in a second arrangement. The device (1) further comprises a unidirectional coupling (100) which is adapted and arranged to allow a relative rotation between the dial link (25a) and the number sleeve (24) in a first direction while preventing relative rotation between the dial link (25a) and the number sleeve (24) in a direction opposite to the first direction when the dial link (25a) and the number sleeve (24) are in the second arrangement.
摘要翻译：一种药物输送装置（1），其包括壳体（4），导螺杆（22），其在剂量设定期间和剂量递送期间相对于壳体（4）可旋转地固定，并且在输送方向上可轴向移动相对于用于剂量输送的壳体（4），与壳体（4）螺纹接合以相对于壳体（4）可旋转的数字套筒（23）以及可轴向移动并且可旋转的拨号连杆（25a）相对于用于剂量设定的壳体（4），并且防止相对于壳体（4）旋转用于剂量递送。当拨盘连杆（25a）和数字套筒（24）处于第一布置时，拨号连杆（25）可旋转地固定有数字套筒（23），数字套筒（24）和拨盘连杆（25a）当拨盘连杆（25）和数字套筒（24）处于第二布置时，它们可相对于彼此旋转。所述装置（1）还包括一个单向联轴器（100），其被适配和布置成允许在第一方向上在拨盘连杆（25a）和数字套管（24）之间的相对旋转，同时防止拨号连杆 25a）和数字套筒（24）在与第一方向相反的方向上，当拨盘连杆（25a）和数字套筒（24）处于第二布置时。

8. 发明申请

WO2015035379A1 SEALED SELF-ACTIVATING INJECTON DEVICE FOR DELIVERY OF MEDICINE FROM A PREFILLED CARTRIDGE OR VIAL 审中-公开
标题翻译：密封自动激活装置，用于从预制的盒子或VIAL中输送药物
公开(公告)号：WO2015035379A1
公开(公告)日：2015-03-12
申请号：PCT/US2014/054775
申请日：2014-09-09
申请人： COVIDIEN LP
发明人： STRADER, David, L.
IPC分类号： A61L2/10 , A61M5/24 , A61M5/32 , A61M5/20
CPC分类号： A61M5/2466 , A61L2/081 , A61L2/10 , A61M5/24 , A61M5/31578 , A61M5/3202 , A61M2005/2073 , A61M2005/247 , Y10T29/4984
摘要： The disclosed embodiment relates to an injection device that is a single patient use, disposable device containing a needle and a cartridge containing a drug or pharmaceutical product. The device is initially provided in a pre-armed configuration wherein the needle sheath maintains cantilever locking tabs on the housing in a position to the maintain the needle in a position separated from the septum of a cartridge. To arm the device, the practitioner removes the needle sheath and pushes down the plunger assembly. The cantilever locking tabs flex outwardly thereby allowing the cartridge-to-housing interface and the cartridge to move forward whereby the butt end of the needle punctures the septum of the cartridge. Additionally, the cantilever locking tabs form a stop configuration with the housing of the device. The disclosed embodiment is particularly adaptable to dental anesthetic applications, as well as other medical and veterinary applications.
摘要翻译：所公开的实施例涉及一种单一患者使用的注射装置，包含针的一次性装置和包含药物或药物产品的药筒。该装置最初以预先布置的配置提供，其中针护套将壳体上的悬臂锁定突片保持在将针保持在与药筒的隔膜分离的位置的位置。为了使装置固定，从业者将移除针鞘并推下柱塞组件。悬臂锁定片向外弯曲，从而允许盒与壳体之间的接口向前移动，由此针的对接端刺穿盒的隔膜。此外，悬臂锁定突片与装置的外壳形成停止构型。所公开的实施例特别适用于牙科麻醉应用以及其他医学和兽医学应用。

9. 发明申请

WO2015007817A1 INDICATION ASSEMBLY 审中-公开
标题翻译：指示装置
公开(公告)号：WO2015007817A1
公开(公告)日：2015-01-22
申请号：PCT/EP2014/065336
申请日：2014-07-17
申请人： SANOFI
发明人： OAKLEY, Tom , SCHUMANN, Matt , MILNE, Stuart
IPC分类号： A61M5/20 , A61M5/24 , A61M5/315 , A61M5/31
CPC分类号： A61M5/31553 , A61M5/20 , A61M5/24 , A61M5/31538 , A61M5/31578 , A61M2005/3126 , A61M2005/3154
摘要： An indication assembly (100) is presented. The indication assembly (100) comprises indication members (110, 120) further comprising interaction features (111, 121). The indication assembly (100) comprises a locking member (130) which is movable with respect to the indication members (110, 120) between a locking position and a non- locking position. The locking member (130) comprises a locking member feature (131), wherein the indication members (110, 120) are rotatable relative to the locking member (130) around an axis (x). The indication assembly (100) is configured such that when the locking member (130) is in the non-locking position, the indication members (110, 120) are rotatable by a predetermined angle in a first rotational direction. The indication assembly (100) is configured such that when the locking member (130) is in the non- locking position and the indication members (110, 120) are rotated by the predetermined angle with respect to the locking member (130), the locking member feature (131) interacts with the interaction feature (111) such that the locking member (130) is displaced into the locking position.
摘要翻译：显示指示组件（100）。指示组件（100）包括还包括交互特征（111,121）的指示构件（110,120）。指示组件（100）包括可在锁定位置和非锁定位置之间相对于指示构件（110,120）移动的锁定构件（130）。锁定构件（130）包括锁定构件特征（131），其中指示构件（110,120）可围绕轴线（x）相对于锁定构件（130）旋转。指示组件（100）构造成使得当锁定构件（130）处于非锁定位置时，指示构件（110,120）可沿第一旋转方向旋转预定角度。指示组件（100）构造成使得当锁定构件（130）处于非锁定位置并且指示构件（110,120）相对于锁定构件（130）旋转预定角度时，锁定构件特征（131）与相互作用特征（111）相互作用，使得锁定构件（130）移动到锁定位置。

10. 发明申请

WO2014093107A1 MEDICATION INJECTOR WITH NEAR-EMPTY ALERT 审中-公开
标题翻译：药物注射器具有不良警报
公开(公告)号：WO2014093107A1
公开(公告)日：2014-06-19
申请号：PCT/US2013/073212
申请日：2013-12-05
申请人： MERCK SHARP & DOHME CORP. , BASILE, Peter, A. , GIVAND, Jeffrey, C. , PERSAK, Steven, Carl
发明人： BASILE, Peter, A. , GIVAND, Jeffrey, C. , PERSAK, Steven, Carl
IPC分类号： A61M5/315
CPC分类号： A61M5/5086 , A61M5/31511 , A61M5/31535 , A61M5/31541 , A61M5/3155 , A61M5/31578 , A61M5/31583 , A61M5/32 , A61M2005/3125 , A61M2005/3126 , A61M2205/584
摘要： A medication injector that has an alert indicator that alerts the user when the medication injector is approaching near the end of its medication supply is disclosed. The alert indicator gives the user an opportunity to make preparations to obtain additional medication for the injector if there is an insufficient amount of medication in the injector to enable the user to dispense the required dosage amount with the next injection. Initially, the alert indicator is not visible to the user, but becomes visible to the user when the injector is near empty.
摘要翻译：公开了一种药物注射器，其具有警报指示器，其在药物注射器在其药物供应的末端附近接近时警告用户。如果注射器中的药物量不足以使用户能够在下一次注射中分配所需的剂量，警报指示器给予用户准备以获得用于注射器的额外药物的机会。最初，警报指示器对用户不可见，但当注射器接近空时，用户可以看到警报指示器。

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