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1. 发明申请

WO2019055719A1 METHODS AND APPARATUS FOR INDUCING OR MODIFYING SLEEP 审中-公开
公开(公告)号：WO2019055719A1
公开(公告)日：2019-03-21
申请号：PCT/US2018/050974
申请日：2018-09-13
申请人： MASSACHUSETTS INSTITUTE OF TECHNOLOGY , NUVU, LLC
发明人： GOSSMAN, Nir , WANG, David , BOYDEN, Edward S.
IPC分类号： A61M21/00
CPC分类号： A61M21/00 , A61M2021/0027 , A61M2021/0044 , A61M2021/0055 , A61M2205/3375 , A61M2205/3561 , A61M2205/50 , A61M2205/52 , A61M2230/06 , A61M2230/10 , A61M2230/14 , A61M2230/42 , A61M2230/63
摘要： A neuromodulator may output stimuli that causes a user to fall asleep faster than the user would in the absence of the stimuli. Alternatively, the stimuli may modify a sleep state or behavior associated with a sleep state, or may cause or hinder a transition from a waking state to a sleep state or from a sleep state to another sleep state. The neuromodulator may take electroencephalography measurements. Based on these measurements, the neuromodulator may detect, in real time, instantaneous amplitude and instantaneous phase of an endogenous brain signal. The neuromodulator may output stimulation that is, or that causes sensations which are, phase-locked with the endogenous brain signal. In the course of calculating instantaneous phase and amplitude, the neuromodulator may perform an endpoint-corrected Hilbert transform. The stimuli may comprise auditory, visual, electrical, magnetic, vibrotactile or haptic stimuli.

2. 发明申请

WO2019016768A1 DEVICE FOR SIGHTLESS PEOPLE DROPPER 审中-公开
公开(公告)号：WO2019016768A1
公开(公告)日：2019-01-24
申请号：PCT/IB2018/055410
申请日：2018-07-20
申请人： BIOCUBICA S.R.L.
发明人： SALITO, Caterina , BOVIO, Dario , UVA, Barbara , CARDANI, Matteo , QUINZI, Mauro
IPC分类号： A61M5/168 , G01F23/26
CPC分类号： A61M5/1689 , A61M2205/3317 , A61M2205/3561 , A61M2205/3584 , A61M2205/505 , A61M2205/52 , A61M2205/581 , G01F13/008 , G01F15/0755 , G01F23/263
摘要： A universal dropper device for vision-impaired people, suitable for providing a sound or vocal indication of the drop count of a liquid substance, for example a medicinal substance, while being poured into a container; the dropper device comprises a container 10 provided with a capacitive sensor 15 on the bottom 14, adapted to supply detection signals SR for detecting the drops 11; the capacitive sensor 15 is operatively connected to a process unit 16 suitable to generate SC counting signals co-related to the detection signals SR of the drops 11 emitted by the sensor 15; a sound module 18 comprising a sound transducer 19 provides sound signals or vocal information SO / SV co-related to the drop counting signals SC generated by the process unit 16. The container 10 for collecting the drops 11 may consist of a glass, a cup, a spoon, or may have any other suitable configuration.

3. 发明申请

WO2018201018A1 ALARM SYSTEM FOR INTRAVENOUS PUMP OR CATHETER BASED UPON FUZZY LOGIC 审中-公开
公开(公告)号：WO2018201018A1
公开(公告)日：2018-11-01
申请号：PCT/US2018/029901
申请日：2018-04-27
申请人： UNIVERSITY OF WASHINGTON
发明人： BOSQUE, Elena, M.
IPC分类号： A61B5/00 , A61B5/0215 , A61B5/03 , A61B5/145 , A61B5/20 , A61M25/00
CPC分类号： A61B5/03 , A61B5/0002 , A61B5/0205 , A61B5/021 , A61B5/02141 , A61B5/0215 , A61B5/02152 , A61B5/14539 , A61B5/14551 , A61B5/4836 , A61B5/4839 , A61B5/6852 , A61B5/7264 , A61B5/746 , A61B2503/04 , A61B2503/06 , A61B2562/0247 , A61M5/14212 , A61M2005/16868 , A61M2005/1726 , A61M2205/18 , A61M2205/3561 , A61M2205/505 , A61M2205/52
摘要： In some embodiments, a self-monitoring intravenous catheter system is provided. An alarm controller is provided that receives signals representing a pH value, an oxygen saturation value, and a pressure value in proximity to the distal end of the catheter. By performing a fuzzy logic analysis of the values, the alarm controller is able to detect that the catheter is about to fail or has failed, and can cause alerts to be presented. In some embodiments, an intravenous catheter is provided that has a pH sensor and an oximeter disposed at a distal end of the catheter to obtain the pH value and oxygen saturation values analyzed by the alarm controller. Embodiments of the catheter and self- monitoring intravenous catheter system may be particularly useful in treating neonates, who are sensitive to catheter failure and are not capable of detecting the signs of failure themselves.

4. 发明申请

WO2018172935A1 VERFAHREN ZUM BETREIBEN VON ZUMINDEST EINEM BEATMUNGSGERÄT IN EINEM KOMMUNIKATIONSNETZWERK 审中-公开
公开(公告)号：WO2018172935A1
公开(公告)日：2018-09-27
申请号：PCT/IB2018/051862
申请日：2018-03-20
申请人： IASSET AG
发明人： FRIBERG, Harri , DAESCHER, Jakob
IPC分类号： G16H40/67 , G16H20/40 , A61M16/00
CPC分类号： G16H20/40 , A61B5/0002 , A61B5/0205 , A61B5/021 , A61B5/0402 , A61M16/0051 , A61M16/022 , A61M2205/3553 , A61M2205/3561 , A61M2205/3584 , A61M2205/3592 , A61M2205/505 , A61M2205/52 , A61M2209/01 , A61M2230/04 , A61M2230/30 , A61M2230/50 , G16H40/67
摘要： Die Erfindung betrifft ein Verfahren zum Betreiben von zumindest einem Beatmungsgerät (12) in einem Kommunikationsnetzwerk (11), wobei das Kommunikationsnetzwerk (11) zumindest eine Verarbeitungseinheit (30) aufweist, vorteilhaft eine Cloud, und die zumindest eine Verarbeitungseinheit (30) eine Recheneinheit (32) aufweist, sowie das zumindest eine Beatmungsgerät (12) über ein Kommunikationsmodul (25) mit dem Kommunikationsnetzwerk (11) verbunden ist. Dabei werden die Beatmungsgerätdaten von dem zumindest einen Beatmungsgerät (12) an das Kommunikationsmodul (25) übermittelt (Schritt a)) und anschliessend werden die übermittelten Beatmungsgerätdaten vom Kommunikationsmodul (25) an die zumindest eine Verarbeitungseinheit (30) gesendet (Schritt b)). Weiters werden die gesendeten Beatmungsgerätdaten in der zumindest einen Verarbeitungseinheit (30) analysiert (Schritt c)), die analysierten Beatmungsgerätdaten in der Recheneinheit (32) überarbeitet (Schritt d)) und anschliessend von der zumindest einen Verarbeitungseinheit (30) auf ein Kommunikationsmodul (25) und/oder von der zumindest einen Verarbeitungseinheit (30) auf zumindest ein externes Empfangsgerät (40, 41) übertragen (Schritt e)). Anschliessend werden die übertragenen Beatmungsgerätdaten verwendet (Schritt f)).

5. 发明申请

WO2018075981A2 METHOD, SYSTEM AND APPARATUS FOR CONTROLLED DELIVERY OF OPIOID AND OTHER MEDICATIONS 审中-公开
标题翻译：用于控制递送阿片类药物和其他药物的方法，系统和设备
公开(公告)号：WO2018075981A2
公开(公告)日：2018-04-26
申请号：PCT/US2017/057749
申请日：2017-10-20
申请人： SOMNIFERUM LABS LLC
发明人： LANZKOWSKY, M.D., David
IPC分类号： A61M11/04 , A61M15/00 , A61P25/04 , A61P25/30
CPC分类号： A61M11/042 , A61B5/1171 , A61B5/1172 , A61B5/14542 , A61B5/1455 , A61B5/4818 , A61G10/02 , A61K9/0043 , A61K9/007 , A61K31/485 , A61K31/675 , A61K31/7048 , A61K31/706 , A61K47/10 , A61K47/26 , A61M11/003 , A61M11/007 , A61M11/041 , A61M15/0021 , A61M15/0065 , A61M15/0066 , A61M15/008 , A61M15/0081 , A61M15/0085 , A61M15/0086 , A61M15/009 , A61M16/22 , A61M2016/0039 , A61M2202/048 , A61M2202/064 , A61M2205/18 , A61M2205/276 , A61M2205/3344 , A61M2205/3368 , A61M2205/3553 , A61M2205/3561 , A61M2205/3584 , A61M2205/36 , A61M2205/50 , A61M2205/505 , A61M2205/581 , A61M2205/582 , A61M2205/583 , A61M2205/587 , A61M2205/6009 , A61M2205/6054 , A61M2205/609 , A61M2230/04 , A61M2230/06 , A61M2230/08 , A61M2230/10 , A61M2230/20 , A61M2230/201 , A61M2230/30 , A61M2230/42 , A61M2230/432 , A61M2230/50 , A61M2230/60 , A61M2230/62 , A61M2230/65 , A61M2240/00 , A61P25/04 , A61P25/30 , A61M2202/0007 , A61M2230/005
摘要： A method, system and apparatus for administering various medicaments including those for treating pain and substance dependency are disclosed. The apparatus is a unit for heat activation of a morphine opiate liquid concentrate mixed with a carrier substance to produce inhaled gas. The method includes inhaling the heat activated gaseous vapor concentrate for pain relief, to treat substance dependency or administration of other medicaments. The system includes a heat vaporization unit with security, control and communication capability to provide effective patient care and ensure safety.
摘要翻译：公开了用于施用包括用于治疗疼痛和物质依赖性的各种药物的方法，系统和设备。该设备是用于热激活与载体物质混合的吗啡阿片剂液体浓缩物以产生吸入气体的单元。该方法包括吸入热激活的气态蒸汽浓缩物以缓解疼痛，治疗物质依赖性或其他药物的施用。该系统包括具有安全性，控制和通信能力的热汽化单元，以提供有效的患者护理并确保安全。

6. 发明申请

WO2018017391A1 PORTABLE NEGATIVE-PRESSURE WOUND CLOSURE SYSTEM 审中-公开
标题翻译：便携式负压伤口闭合系统
公开(公告)号：WO2018017391A1
公开(公告)日：2018-01-25
申请号：PCT/US2017/041945
申请日：2017-07-13
申请人： KCI LICENSING, INC.
发明人： KIESWETTER, Kristine, M. , MARCROFT, Michael , LOCKE, Christopher, Brian
IPC分类号： A61M1/00 , A61M27/00
CPC分类号： A61F13/00068 , A61F13/0216 , A61M1/0088 , A61M2205/3553 , A61M2205/3561 , A61M2205/3584 , A61M2205/3592 , A61M2209/088
摘要： A portable therapy system for treating a tissue site with negative pressure is disclosed. The therapy system includes an absorbent wound dressing, a low-profile fluid conduit, a therapy unit with a vacuum pump and a communications device for transmitting operational data of the therapy unit and for communicating wirelessly with a remote device. The therapy unit may comprise an integrated inductive coil, which may facilitate wireless charging of batteries of the therapy unit while being worn, during periods of patient rest, or both.
摘要翻译：公开了一种用于用负压治疗组织部位的便携式治疗系统。治疗系统包括吸收性伤口敷料，低剖面流体导管，具有真空泵的治疗单元以及用于传输治疗单元的操作数据并用于与远程装置无线通信的通信装置。治疗单元可以包括集成的感应线圈，其可以有助于在佩戴期间，在患者休息期间或两者期间对治疗单元的电池进行无线充电。

7. 发明申请

WO2017142874A2 ASPIRATION DEVICES AND ANCHORED FLOW DIVERTING DEVICES 审中-公开
标题翻译：吸入装置和锚定流动分流装置
公开(公告)号：WO2017142874A2
公开(公告)日：2017-08-24
申请号：PCT/US2017/017824
申请日：2017-02-14
申请人： INSERA THERAPEUTICS, INC.
发明人： JANARDHAN, Vallabh , JANARDHAN, Vikram
IPC分类号： A61M1/00
CPC分类号： A61M1/0033 , A61B17/12113 , A61M1/0023 , A61M2025/0042 , A61M2205/3561 , A61M2205/50
摘要： An aspiration system includes a pump and a control system in communication with the pump. The control system includes a microcontroller, an antenna configured to receive a signal, and a pump control board in communication with the microcontroller. The antenna is in communication with the microcontroller. Upon receiving the signal, the pump control board operates the pump to create negative pressure according to the signal.
摘要翻译：吸入系统包括泵和与泵连通的控制系统。控制系统包括微控制器，配置为接收信号的天线以及与微控制器通信的泵控制板。天线与微控制器通信。接收到信号后，泵控制板根据信号操作泵产生负压。

8. 发明申请

WO2017132000A1 FACILITATING INTEGRITY OF TELEMETRY CONNECTIVITY BETWEEN AN IMPLANTABLE DEVICE AND A REMOTE DEVICE 审中-公开
标题翻译：促进可植入装置与远程装置之间的遥测连接的完整性
公开(公告)号：WO2017132000A1
公开(公告)日：2017-08-03
申请号：PCT/US2017/013722
申请日：2017-01-17
申请人： MEDTRONIC, INC.
发明人： YODER, Matthew R. , ZHANG, Bo , KIVI, Gary P. , SANDEN, Richard A.
IPC分类号： A61N1/372 , A61N1/37 , A61N1/39 , A61M5/14 , A61N1/05 , A61N1/36 , A61N1/362 , A61N1/365
CPC分类号： A61N1/37252 , A61M5/14276 , A61M2205/3523 , A61M2205/3561 , A61M2205/52 , A61N1/0563 , A61N1/0568 , A61N1/0573 , A61N1/36007 , A61N1/3605 , A61N1/362 , A61N1/36507 , A61N1/36564 , A61N1/37217 , A61N1/3956 , G16H40/67
摘要： Systems, apparatus, methods and computer-readable storage media that facilitate monitoring the integrity of telemetry connectivity between an implantable device and an external device are provided. In one embodiment, an implantable device includes a monitoring component that monitors advertisement signal information identifying an amount of advertisement signals transmitted to the external device within a defined time period, and telemetry session information identifying an amount of the telemetry sessions that are established between the external device and the implantable device within the defined time period. A connectivity assessment component of the implantable device further determines whether a telemetry connectivity problem exists between the external device and the implantable device based on a degree of miscorrelation between the advertisement signal information and the telemetry session information.
摘要翻译：提供了便于监测可植入设备和外部设备之间的遥测连接的完整性的系统，设备，方法和计算机可读存储介质。在一个实施例中，可植入设备包括监视组件，该监视组件监视标识在定义的时间段内向外部设备传送的广告信号的量的广告信号信息，以及遥测会话信息，标识在外部设备之间建立的遥测会话的数量装置和植入式装置在限定的时间段内。可植入设备的连接性评估组件还基于广告信号信息和遥测会话信息之间的错误相关程度来确定外部设备和可植入设备之间是否存在遥测连接性问题。

9. 发明申请

WO2017115376A1 APPARATUS AND METHOD FOR EARLY DETECTION, MONITORING AND TREATING SLEEP DISORDERS 审中-公开
标题翻译：用于早期检测，监测和治疗睡眠疾病的装置和方法
公开(公告)号：WO2017115376A1
公开(公告)日：2017-07-06
申请号：PCT/IL2016/051402
申请日：2016-12-29
申请人： SLEEPOW LTD.
发明人： GURIEVSKY, Yacov , RATMANSKY, Mordehai
IPC分类号： A61B5/08 , A61B5/113 , A61M21/02
CPC分类号： A61B5/4812 , A61B5/002 , A61B5/02416 , A61B5/0816 , A61B5/0873 , A61B5/1116 , A61B5/1135 , A61B5/14551 , A61B5/4818 , A61B5/4836 , A61B5/681 , A61B5/6833 , A61B7/003 , A61B2562/0204 , A61B2562/0219 , A61F5/56 , A61M21/02 , A61M2021/0016 , A61M2021/0022 , A61M2021/0027 , A61M2021/0044 , A61M2021/0061 , A61M2021/0072 , A61M2205/3303 , A61M2205/3306 , A61M2205/332 , A61M2205/3334 , A61M2205/3368 , A61M2205/3375 , A61M2205/3553 , A61M2205/3561 , A61M2205/3569 , A61M2205/3584 , A61M2205/3592 , A61M2205/50 , A61M2205/581 , A61M2205/583 , A61M2205/609 , A61M2209/088 , A61M2230/06 , A61M2230/10 , A61M2230/205 , A61M2230/42 , A61M2230/60 , A61M2230/62 , A61M2230/63 , A61M2230/65 , A61M2230/005
摘要： Devices for monitoring one or more parameters of a subject, and related methods and systems, are disclosed. The device comprises a support element configured and arranged to detachably attach over a skin region of a chest area of a subject, an optical sensor assembly mounted to said support element and configured and arranged to conduct optical measurements in said chest area and generate optical measurement data indicative of said one or more parameters of said subject, a volumetric sensor assembly mounted to said support element and configured and operable to measure chest expansions and retractions of said subject and generate volumetric measurement data indicative of the expansions and retractions of the chest of said subject, and a control unit mounted to said support element and configured and operable to process said optical and volumetric measurement data for removing interferences introduced into said optical measurements due to said chest expansions and retractions.
摘要翻译：公开了用于监视对象的一个或多个参数的设备以及相关的方法和系统。该装置包括支撑元件，该支撑元件被配置和布置成可拆卸地附接在对象的胸部区域的皮肤区域上;光学传感器组件，其安装到所述支撑元件并且被配置和布置为在所述胸部区域中进行光学测量并生成光学测量数据指示所述对象的所述一个或多个参数;体积传感器组件，其安装到所述支撑元件并且被配置和可操作以测量所述对象的胸部扩张和缩回，并生成指示所述对象的胸部的扩张和缩回的体积测量数据以及控制单元，所述控制单元安装到所述支撑元件并且被配置和可操作以处理所述光学和体积测量数据，以消除由于所述胸部扩张和缩回而引入到所述光学测量中的干扰。

10. 发明申请

WO2017106247A1 DRUG DELIVERY STORAGE DEVICE AND SYSTEM 审中-公开
标题翻译：药物递送存储装置和系统
公开(公告)号：WO2017106247A1
公开(公告)日：2017-06-22
申请号：PCT/US2016/066490
申请日：2016-12-14
申请人： AMGEN INC.
发明人： TAMTORO, Ferry , YANG, Huaying , GIBSON, Scott, R. , BUSBY, Donald , SHULTZ, Peter, V. , TAHA, Basel, Hasan , MCCULLOUGH, Adam, B.
IPC分类号： G06F19/00 , A61M5/20 , A61J1/03
CPC分类号： G06F19/3468 , A61J1/03 , A61M5/002 , A61M5/20 , A61M2205/3561 , A61M2205/6009 , G06F19/00
摘要： A drug delivery system includes a storage container defining one or more storage compartments and having at least one container sensor coupled thereto, a container condition change mechanism coupled to the storage container for imparting a change on one or more conditions of the one or more storage compartments, at least one drug delivery device adapted to deliver a drug to a user and adapted to be at least partially disposed within one or more of the one or more storage compartments, at least one delivery device sensor, a delivery device condition change mechanism coupled to the drug delivery device, and a controller coupled to the storage container. The storage container may be adapted to hold a number of drug delivery devices within a number of sealable storage compartments. The container sensor is adapted to sense a condition of the storage container, and the delivery device sensor is adapted to sense a condition of the at least one drug delivery device. The controller is adapted to instruct the container condition change mechanism and/or the delivery device change mechanism to impart a change on at least one condition of the storage container and/or the drug delivery device.
摘要翻译：药物输送系统包括：储存容器，其限定一个或多个储存室并具有至少一个与其耦合的容器传感器;容器状态改变机构，其耦合到储存容器以用于对一个或多个所述一个或多个储存室的状况，至少一个药物输送装置，所述至少一个药物输送装置适于将药物输送至使用者并且适于至少部分地布置在所述一个或多个储存室中的一个或多个储存室内;至少一个输送装置传感器，耦合到药物输送装置的输送装置状态改变机构，以及耦合到储存容器的控制器。储存容器可以适于将多个药物输送装置保持在多个可密封的储存室内。容器传感器适于感测储存容器的状况，并且递送装置传感器适于感测至少一个药物递送装置的状况。控制器适于指示容器状态改变机构和/或输送装置改变机构在储存容器和/或药物输送装置的至少一个状态上给予改变。

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