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1. 发明申请

WO2019152376A1 ARRHYTHMIAS DETECTION AND REPORTING SYSTEM 审中-公开
公开(公告)号：WO2019152376A1
公开(公告)日：2019-08-08
申请号：PCT/US2019/015584
申请日：2019-01-29
申请人： CARDIAC PACEMAKERS, INC.
发明人： PERSCHBACHER, David L. , SAHA, Sunipa , MAHAJAN, Deepa
IPC分类号： A61B5/02 , A61B5/0245 , A61B5/046 , A61N1/365 , A61N1/37 , A61B5/0432 , A61B5/0404 , A61B5/0464 , A61B5/044
CPC分类号： A61B5/046 , A61B5/0006 , A61B5/0031 , A61B5/0205 , A61B5/0215 , A61B5/02405 , A61B5/02438 , A61B5/0245 , A61B5/04012 , A61B5/042 , A61B5/0464 , A61B5/0816 , A61B5/1118 , A61B5/14542 , A61B5/6823 , A61B5/7264 , A61B5/7275 , A61B5/7282 , A61N1/0504 , A61N1/08 , A61N1/3624 , A61N1/365 , A61N1/36521 , A61N1/36535 , A61N1/3655 , A61N1/36564 , A61N1/36578 , A61N1/37 , A61N1/3704 , A61N1/395 , A61N1/3956 , A61N1/39622 , A61N1/3987 , G16H15/00 , G16H40/63 , G16H50/30
摘要： Systems and methods for managing cardiac arrhythmias are discussed. A data management system receives a first detection algorithm including a detection criterion for detecting a cardiac arrhythmia. An arrhythmia detector detects arrhythmia episodes from a physiologic signal using a second detection algorithm that is different from and has a higher sensitivity for detecting the cardiac arrhythmia than the first detection algorithm. The arrhythmia detector assigns a detection indicator to each of the detected arrhythmia episodes. The detection indicator indicates a likelihood that the detected arrhythmia episode satisfies the detection criterion of the first detection algorithm. The system prioritizes the detected arrhythmia episodes according to the assigned detection indicators, and outputs the arrhythmia episodes to a user or a process according to the episode prioritization.

2. 发明申请

WO2019118309A1 METHOD, MODULE AND SYSTEM FOR ANALYSIS OF PHYSIOLOGICAL SIGNAL 审中-公开
公开(公告)号：WO2019118309A1
公开(公告)日：2019-06-20
申请号：PCT/US2018/064644
申请日：2018-12-10
申请人： ADAPTIVE, INTELLIGENT AND DYNAMIC BRAIN CORPORATION (AIDBRAIN) , HUANG, Norden, E.
发明人： HUANG, Norden, E.
IPC分类号： A61B5/0402 , A61B5/00 , A61B5/02 , A61B5/04
CPC分类号： A61B5/048 , A61B5/0006 , A61B5/021 , A61B5/04008 , A61B5/044 , A61B5/0488 , A61B5/4088 , A61B5/72 , A61B5/7253 , A61B5/743
摘要： The present disclosure provides a non-transitory computer program product embodied in a comparer-readable medium, and when executed' by one or more analysis module, providing a visual output for presenting physiological signals of a cardiovascular system. The non- transitory computer program product comprises a first axis representing subsets of intrinsic mode functions (IMFs); a second axis representing a function of signal strength in a time interval; and a plurality of visual elements, each of the visual elements being defined by the first axis and the second axis, and each of the visual elements comprising a plurality of analyzed data units collected over the time interval.

3. 发明申请

WO2019113323A1 SYSTEM TO IMPROVE CLINICAL WORKFLOW 审中-公开
公开(公告)号：WO2019113323A1
公开(公告)日：2019-06-13
申请号：PCT/US2018/064260
申请日：2018-12-06
申请人： CARDIAC PACEMAKERS, INC.
发明人： MAHAJAN, Deepa , SEN, Bhaskar , SAHA, Sunipa , PERSCHBACHER, David L.
IPC分类号： G16H50/70 , G16H50/20 , A61B5/00 , A61B5/046 , A61N1/372 , A61B5/0402
CPC分类号： G16H50/20 , A61B5/0006 , A61B5/0245 , A61B5/046 , A61B5/7267 , A61N1/37258 , G06N20/00 , G16H10/60 , G16H50/30 , G16H50/70
摘要： Described herein are systems and methods for classifying clinical episodes in order to more accurately generate alerts for those episodes that warrant them. In some embodiments, alerts are only generated for those episodes that are new or different from previous episodes, where the previous episodes have been found to be not significant enough to warrant an alert.

4. 发明申请

WO2019108416A1 DIRECT ELECTROCARDIOGRAPHY MONITORING FOR ATRIAL FIBRILLATION DETECTION 审中-公开
公开(公告)号：WO2019108416A1
公开(公告)日：2019-06-06
申请号：PCT/US2018/061555
申请日：2018-11-16
申请人： EDWARDS LIFESCIENCES CORPORATION
发明人： SCHWARTZ, Robert, S. , ROWE, Stanton, J. , BAK-BOYCHUK, Gregory
IPC分类号： A61B5/00 , A61B5/042 , A61B5/046 , A61B5/07 , A61N1/372 , A61N1/362 , A61N1/375 , A61B5/029 , A61N1/05
CPC分类号： A61B5/0422 , A61B5/0006 , A61B5/0031 , A61B5/029 , A61B5/046 , A61B5/076 , A61B5/4836 , A61B5/686 , A61B5/746 , A61B2560/0412 , A61N1/059 , A61N1/0597 , A61N1/3624 , A61N1/36507 , A61N1/37205 , A61N1/37518 , A61N2001/058
摘要： A direct-implantable electrocardiographic (ECG) probe device includes a biocompatible housing, a battery disposed within the housing, one or more electrodes including an ECG electrode configured to sense an electrical signal in tissue of an atrium of a heart, circuitry disposed at least partially within the housing and configured to generate an ECG signal and wirelessly transmit the ECG signal through a chest wall, and an attachment structure configured to facilitate the attachment of the ECG probe device to a surface of the atrium.

5. 发明申请

WO2019011021A1 用于屏蔽电磁波的生物电信号采集装置及生物电信号采集装置审中-公开
公开(公告)号：WO2019011021A1
公开(公告)日：2019-01-17
申请号：PCT/CN2018/082697
申请日：2018-04-11
申请人：陈晓苏
发明人：陈晓苏 , 柳仁松 , 徐大智
IPC分类号： A61B5/04
CPC分类号： A61B5/0006 , A61B5/04 , A61B5/0402 , A61B5/0476 , H01B11/06
摘要：一种用于屏蔽电磁波的生物电信号采集装置及生物电信号采集装置，包括：生物电极（1），具有屏蔽结构的信号传输线（2）；其中，信号传输线（2）的一端与生物电极（1）电连接，另一端与信号处理装置电连接；生物电极（1）配置成采集生物信号；信号传输线（2）配置成传输生物信号以及屏蔽电磁波。用于屏蔽电磁波的生物电信号采集装置及生物电信号采集装置能够对电磁波进行屏蔽，使所测得的生物信号免受电磁波的干扰。

6. 发明申请

WO2018040680A1 METHOD AND APPARATUS FOR DETERMINING BLOOD PRESSURE 审中-公开
标题翻译：确定血压的方法和设备
公开(公告)号：WO2018040680A1
公开(公告)日：2018-03-08
申请号：PCT/CN2017/089150
申请日：2017-06-20
申请人： BOE TECHNOLOGY GROUP CO., LTD.
发明人： WANG, Guohe
IPC分类号： A61B5/021
CPC分类号： A61B5/04011 , A61B5/0006 , A61B5/02108 , A61B5/02125 , A61B5/0245 , A61B5/0402 , A61B5/0456 , A61B5/6801 , A61B5/6898 , A61B5/7278
摘要： A method for determining a blood pressure of a user includes: collecting an electrocardiography (ECG) signal and a pulse wave signal from the user (S101), extracting characteristic parameters of the user from the ECG signal and the pulse wave signal (S102), establishing a characteristic vector of the user based on personal information of the user and the characteristic parameters of the user (S103), and determining the blood pressure of the user based on the characteristic vector of the user and a characteristic-vector-and-blood-pressure relational model (S104). A blood pressure determining apparatus based on the method is also provided, which includes an acquisition portion (401), a characteristic parameter determination portion (402), a characteristic vector determination portion (403), and a blood pressure determination portion (404).
摘要翻译：用于确定用户的血压的方法包括：收集来自用户的心电图（ECG）信号和脉搏波信号（S101），从ECG信号中提取用户的特征参数以及脉波信号（S102），基于用户的个人信息和用户的特征参数建立用户的特征向量（S103），并基于用户的特征向量确定用户的血压，以及特征向量和血压关系模型（S104）。还提供了基于该方法的血压确定装置，其包括获取部分（401），特征参数确定部分（402），特征向量确定部分（403）以及血压确定部分（404）。

7. 发明申请

WO2017174814A1 BLOOD PRESSURE AND CARDIAC MONITORING SYSTEM AND METHOD THEREOF 审中-公开
标题翻译：血压和心脏监测系统及其方法
公开(公告)号：WO2017174814A1
公开(公告)日：2017-10-12
申请号：PCT/EP2017/058487
申请日：2017-04-10
申请人： ROBERT BOSCH GMBH
发明人： ABRAHAM, Zubin , PETERS, Christian , ROCZNIK, Thomas , YEE, Seow Yuen , LAERMER, Franz , SHAH, Mohak , WALDMANN, Jan , HENRICI, Fabian
IPC分类号： A61B5/021 , A61B5/0285 , A61B5/0456 , A61B5/00 , A61B5/11 , A61B5/024
CPC分类号： A61B5/021 , A61B5/0002 , A61B5/0006 , A61B5/0022 , A61B5/0205 , A61B5/02108 , A61B5/02125 , A61B5/02416 , A61B5/0285 , A61B5/0295 , A61B5/04012 , A61B5/0402 , A61B5/0456 , A61B5/1102 , A61B5/1107 , A61B5/72 , A61B8/04 , A61B2562/0219
摘要： A blood pressure and cardiac monitoring system includes a sensing assembly, which comprises a first sensor (102a) located at a first axis of a target generating a first time-dependent motion waveform (302) representative of one or more contractile properties of the target's heart and a second sensor (102b) located at a second axis of the target generating a second time dependent motion waveform (304). The processor is configured to determine a first time difference between a vital sign present in the first time dependent motion waveform and the second time dependent motion waveform. A third sensor (102c) located either at the first or the second axis of the target generates a third time dependent waveform (300) representative of the electrical potential due to the depolarization of heart muscle. At least one of the sensors may be configured to either remove motion artifacts (as a reference sensor) or detect attributes from the environment for providing context awareness information.
摘要翻译：血压和心脏监测系统包括感测组件，该感测组件包括位于目标的第一轴处的第一传感器（102a），该第一传感器（102a）生成代表一个第一时间相关运动波形（302）的第一传感器或更多的目标心脏和位于目标的第二轴处的第二传感器（102b）产生第二时间相关运动波形（304）的可收缩属性。处理器被配置为确定存在于第一时间相关运动波形中的生命体征与第二时间相关运动波形之间的第一时间差。位于目标的第一轴或第二轴处的第三传感器（102c）生成表示由于心肌去极化引起的电势的第三时间相关波形（300）。至少一个传感器可以被配置为去除运动伪影（作为参考传感器）或者检测来自环境的用于提供情境感知信息的属性。

8. 发明申请

WO2017136421A1 COMBINING ELECTRONIC MONITORING WITH INHALED PHARMACOLOGICAL THERAPY TO MANAGE CARDIAC ARRHYTHMIAS INCLUDING ATRIAL FIBRILLATION 审中-公开
标题翻译：联合电子监测与吸入药物疗法治疗包括心房颤动在内的心律失常
公开(公告)号：WO2017136421A1
公开(公告)日：2017-08-10
申请号：PCT/US2017/016018
申请日：2017-02-01
申请人： INCARDA THERAPEUTICS, INC.
发明人： NARASIMHAN, Rangachari , BELARDINELLI, Luiz , SCHULER, Carlos A.
IPC分类号： A61K31/4458 , A61B5/0464 , A61B5/046 , A61M15/00
CPC分类号： A61B5/7405 , A61B5/0006 , A61B5/0022 , A61B5/0031 , A61B5/0404 , A61B5/042 , A61B5/0432 , A61B5/044 , A61B5/0452 , A61B5/4839 , A61B5/6898 , A61B2562/222 , A61K9/0019 , A61K9/0078 , A61K9/008 , A61K9/08 , A61K9/10 , A61K9/19 , A61K31/4458 , A61K47/12 , A61M11/00 , A61M11/005 , A61M11/06 , A61M15/00 , A61M15/0085 , A61M15/009 , A61M2205/18 , A61M2205/3303 , A61M2205/3523 , A61M2205/3553 , A61M2205/3561 , A61M2205/3569 , A61M2205/3584 , A61M2205/3592 , A61M2205/502 , A61M2205/52 , A61M2230/04
摘要： Disclosed herein are methods of treating cardiac arrhythmia with electronic monitoring in a timely manner. Also disclosed herein are systems for electronic monitoring of cardiac arrhythmia.
摘要翻译：本文公开了通过电子监测以及时方式治疗心律失常的方法。本文还公开了用于电子监视心律失常的系统。

9. 发明申请

WO2017075856A1 基于小波分析远程心电监护与预警系统及方法审中-公开
公开(公告)号：WO2017075856A1
公开(公告)日：2017-05-11
申请号：PCT/CN2015/096538
申请日：2015-12-07
申请人：福州大学
发明人：王量弘 , 樊明辉
IPC分类号： A61B5/0402
CPC分类号： A61B5/04018 , A61B5/0006 , A61B5/0022 , A61B5/0245 , A61B5/0432 , A61B5/044 , A61B5/046 , A61B5/6823 , A61B5/6831 , A61B5/7232 , A61B5/7275 , A61B5/746 , A61B2560/0214 , G06F19/00
摘要：一种基于小波分析远程心电监护与预警系统及方法，包括一无线心电信号采集装置（11）、一移动终端（12）以及一云存储平台（13）。无线心电信号采集装置（11）穿戴于使用者胸前，用以实时采集心电信号并将心电信号传输至移动终端（12）。移动终端（12）采用小波分析算法分析处理接收到的心电信号，并将处理后的心电信号上传至云存储平台（13）。云存储平台（13）用以存储使用者的个人信息以及心电信号分析得到心电信号的波形特征。这种远程心电监护与预警系统克服了传统心电图信号采集系统的不足，采用基于小波分析和超低功耗蓝牙技术的远程心电监护与预警系统，随时随地对心脏信号进行监护与预警。

10. 发明申请

WO2017059274A1 ENHANCED WEARABLE THERAPY DEVICE PAIRED WITH INSERTABLE CARDIAC MONITOR 审中-公开
标题翻译：增强的耐磨治疗装置与插入式心脏监护仪配对
公开(公告)号：WO2017059274A1
公开(公告)日：2017-04-06
申请号：PCT/US2016/054830
申请日：2016-09-30
申请人： CARDIAC PACEMAKERS, INC.
发明人： LUDWIG, Jacob M. , BALCZEWSKI, Ron A. , GROTBECK, Todd W. , MAILE, Keith R. , SWEENEY, Moira B.
IPC分类号： A61B5/00 , A61B5/0464 , A61B5/046 , A61N1/39 , A61B5/0205 , A61B5/11 , A61B5/08
CPC分类号： A61N1/3987 , A61B5/0006 , A61B5/002 , A61B5/0031 , A61B5/0205 , A61B5/0408 , A61B5/042 , A61B5/046 , A61B5/0464 , A61B5/0816 , A61B5/1102 , A61B5/1116 , A61B5/4836 , A61B5/6805 , A61B5/686 , A61B5/7264 , A61B5/7275 , A61B2505/01 , A61B2560/0443 , A61B2560/0468 , A61N1/3925 , G06F19/00
摘要： A medical system for providing a defibrillation therapy to a patient includes a cardiac monitoring device (CMD) configured to sense and record physiological data indicative of the patient's cardiac function. The CMD includes a communication component. The system also includes an external therapy device configured to deliver defibrillation therapy, and configured to be positioned external to and supported by the patient. The external therapy device includes an external therapy device communication component. The CMD communication component and the external therapy device communication component are configured to operatively couple the CMD and the external therapy device to one another, so as to work as a system to detect and treat fibrillation.
摘要翻译：用于向患者提供除颤疗法的医疗系统包括心脏监测装置（CMD），其被配置为感测和记录指示患者的心脏功能的生理数据。 CMD包括通信组件。该系统还包括外部治疗装置，该外部治疗装置被配置为递送除颤疗法，并且被配置为定位在患者外部并由患者支撑。外部治疗装置包括外部治疗装置通信部件。 CMD通信组件和外部治疗设备通信组件被配置为将CMD和外部治疗设备彼此可操作地耦合，以便作为检测和治疗原纤维化的系统。

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