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1. 发明申请

WO2018075724A1 POWER NOISE REDUCTION FOR AN INTEGRATED BATTERY 审中-公开
标题翻译：降低集成电池的功率噪声
公开(公告)号：WO2018075724A1
公开(公告)日：2018-04-26
申请号：PCT/US2017/057307
申请日：2017-10-19
申请人： CARDIAC PACEMAKERS, INC.
发明人： BALCZEWSKI, Ron A. , LINDER, William J.
IPC分类号： A61N1/378 , A61B5/00 , A61N1/39 , A61B5/053 , A61B5/042
CPC分类号： A61B5/7217 , A61B5/0022 , A61B5/0031 , A61B5/0205 , A61B5/04017 , A61B5/042 , A61B5/0422 , A61B5/0809 , A61B5/1112 , A61B5/1116 , A61B5/1118 , A61B5/14542 , A61B5/4866 , A61B5/686 , A61B2560/0214 , A61B2560/0468 , A61B2562/0204 , A61B2562/0209 , A61B2562/0219 , A61B2562/166 , A61N1/0504 , A61N1/3754 , A61N1/378 , A61N1/3956 , A61N1/3975 , G16H40/67 , H01M2/0202 , H01M10/4257 , H01M2010/4271
摘要： A medical device includes a case and a core assembly. The core assembly includes operational circuitry enclosed within a core assembly housing. The medical device also includes a battery assembly, which includes a battery enclosed within a battery housing. The case includes the core assembly housing and the battery housing. A first electrode is coupled to, and electrically isolated from, the case; and a second electrode is electrically coupled to the case. The second electrode is electrically coupled to the operational circuitry via a sensing pathway that includes a portion of the case. The battery is electrically coupled to the operational circuitry via an energy supply pathway that includes the portion of the case.
摘要翻译：医疗装置包括外壳和核心组件。芯组件包括封闭在芯组件外壳内的操作电路。医疗设备还包括电池组件，其包括封装在电池壳体内的电池。外壳包括核心组件外壳和电池外壳。第一电极连接至壳体并且与壳体电隔离; 并且第二电极电耦合到壳体。第二电极经由包括壳体的一部分的感测路径电耦合到操作电路。电池通过包括壳体部分的能量供应路径电耦合到操作电路。

2. 发明申请

WO2017011240A1 EXTRAVASCULAR MEDICAL ACCESS TOOLS HAVING BORING TIP AND METHODS OF USING SUCH TOOLS 审中-公开
标题翻译：具有镗孔尖端的超声医疗辅助工具及使用这些工具的方法
公开(公告)号：WO2017011240A1
公开(公告)日：2017-01-19
申请号：PCT/US2016/041091
申请日：2016-07-06
申请人： MEDTRONIC, INC.
发明人： DRAKE, Ronald A. , STENER, Lester O. , LANGE, John A. , MACIVER, Mitchell R.
IPC分类号： A61B17/34 , A61N1/05 , A61B17/32 , A61B18/14 , A61B17/00
CPC分类号： A61B17/3468 , A61B17/1691 , A61B17/32002 , A61B2017/00243 , A61B2017/320044 , A61B2017/320056 , A61N1/05 , A61N1/0504
摘要： This disclosure describes various tools and associated methods suitable for gaining access to extravascular spaces. The various tools and associated methods utilize a boring tip that may rotate to aid in safely and effectively crossing diaphragmatic attachments. The boring tip may, in some instances not have any sharp edge. For example, the boring tip may have a dome shape but including at least one surface recessed and offset from a summit of the dome shape. Various mechanisms may be used to control rotation of the boring tip as described herein.
摘要翻译：本公开描述适于获得进入血管外空间的各种工具和相关方法。各种工具和相关方法利用可以旋转的镗孔，以有助于安全和有效地穿过膈肌附件。在某些情况下，无聊尖端可能没有任何尖锐的边缘。例如，镗尖可以具有圆顶形状，但是包括至少一个凹陷并偏离圆顶形状的顶点的表面。可以使用各种机构来控制如本文所述的钻尖的旋转。

3. 发明申请

WO2016168789A1 SYSTEMS, DEVICES, AND METHODS FOR CONTACT MEASUREMENT AND MODULATION OF MATERIAL PROPERTIES 审中-公开
标题翻译：用于接触测量和材料性质调节的系统，装置和方法
公开(公告)号：WO2016168789A1
公开(公告)日：2016-10-20
申请号：PCT/US2016/028017
申请日：2016-04-17
申请人： THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA , THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS
发明人： DAGDEVIREN, Canan , ROGERS, John, A. , SLEPIAN, Marvin, J.
IPC分类号： A61B5/03 , A61B5/00 , A61B5/0205
CPC分类号： A61B5/0205 , A61B5/0051 , A61B5/442 , A61B5/444 , A61B2562/02 , A61B2562/0261 , A61B2562/12 , A61N1/0492 , A61N1/0504 , B81C1/00031 , G16H20/17
摘要： Materials and devices are provided for the sensing and manipulation of biomechanical and physiochemical properties of tissues or tissue surfaces. Examples of use include soft tissues such as skin or adipose tissues or more dense tissues such as muscle or heart or dense tissues such as bone. The materials and devices provide for in vivo measurements of biomechanical properties at the tissue surface, e.g. near surface regions of the epidermis or dermis or underlying structures. The devices can be non-invasive and/or non-destructive to the material and, especially for the biomaterials, can be biocompatible and/or biodegradable. The materials and devices can use ultrathin, stretchable networks of mechanical actuators and sensors constructed with nanoribbons of piezoelectric materials.
摘要翻译：提供材料和装置用于感测和操纵组织或组织表面的生物力学和物理化学性质。使用的实例包括软组织如皮肤或脂肪组织或更致密的组织如肌肉或心脏或致密组织如骨。材料和装置提供体内测量组织表面的生物力学性质，例如，表皮或真皮或底层结构的近表面区域。该装置可以是非侵入性的和/或非破坏性的材料，特别是生物材料可以是生物相容的和/或可生物降解的。材料和器件可以使用机械致动器的超薄可拉伸网络和由压电材料的纳米带构成的传感器。

4. 发明申请

WO2016055513A1 IMPLANTIERBARE ANORDNUNG 审中-公开
标题翻译：可植入装置
公开(公告)号：WO2016055513A1
公开(公告)日：2016-04-14
申请号：PCT/EP2015/073131
申请日：2015-10-07
申请人： NEUROLOOP GMBH
发明人： PLACHTA, Dennis , GIERTHMÜHLEN, Mortimer , STIEGLITZ, Thomas , ZENTNER, Josef
IPC分类号： A61N1/36 , A61N1/05
CPC分类号： A61N1/36175 , A61N1/0504 , A61N1/0556 , A61N1/36117 , A61N1/36125 , A61N1/36139 , A61N1/372 , A61N1/3782
摘要： Implantierbare Anordnung zur ortsselektiven Erfassung neuronaler elektrischer Signale, sowie zur selektiven elektrischen Nervenstimulation, umfassend folgende Komponenten: • Implantierbare Elektrodenanordnung (E) zur ortsselektiven Erfassung der neuronalen elektrischen Signale, selektiven elektrischen Stimulation und zur Erfassung eines EKG-Signals, • eine Auswerte-/Steuereinheit (A/S), in der die Signale zeitaufgelöst derart auswertbar sind, dass ein zu einem physiologischen Parameter, vorzugsweise Blutdruck, korreliertes neuronales Zeitsignal ableitbar ist, • eine Komparatoreinheit (Kl), in der ein Zeitversatz zwischen dem EKG-Signal und dem mit dem physiologischen Parameter korrelierten, neuronalen Zeitsignal ermittelbar ist, • ein Funktionsgenerator (Fl), der innerhalb eines durch die Auswerte-/Steuereinheit (A/S) unter Zugrundelegung des relativen Zeitversatzes ermittelten Zeitfensters sich aus einer Vielzahl n Einzelpulsen (EP) zusammensetzenden und in Phase und zeitlichen Amplitudenverlauf an das abgeleitete, mit dem physiologischen Parameter korrelierte, neuronale Zeitsignal angepasstes Stimulationssignal generiert sowie • einen Signal-Strom-Wandler (SSWl), der das Stimulationssignal zur selektiven elektrischen Stimulation an die Elektrodenanordnung (2) leitet.
摘要翻译：对神经元的电信号，和用于选择性电神经刺激，其包含以下组分的位置的选择性检测植入装置：•为神经元的电信号的位置的选择性检测，选择性电刺激以及用于检测ECG信号，●评估/控制单元的可植入电极组件（E）（A / S），其中，所述信号的时间分辨是这样评价为生理参数，优选血压相关的神经元时间信号可以源自，•比较器（KI），其中，所述ECG信号之间以及与偏移的时间相关的生理参数，神经元时间信号可以被确定，•一个函数发生器（FL），所确定的一个由多个n个单独的脉冲（EP）的相对时间偏移的时间窗口的基础上，所述评估/控制单元（A / S）中构成和相位和时间烯在与生理参数的导出相关产生的振幅曲线，神经刺激信号适配的时间信号，以及·所述刺激信号的信号至电流转换器（SSWL）用于选择性电刺激到电极组件（2）通过。

5. 发明申请

WO2016037145A1 DELIVERY SYSTEM FOR CARDIAC PACING 审中-公开
标题翻译： CARDIAC PACING交付系统
公开(公告)号：WO2016037145A1
公开(公告)日：2016-03-10
申请号：PCT/US2015/048717
申请日：2015-09-04
申请人： ATACOR MEDICAL, INC.
发明人： SANGHERA, Rick , MARCOVECCHIO, Alan , MCGEEHAN, Sean
IPC分类号： A61B17/34
CPC分类号： A61N1/0592 , A61B17/3468 , A61B2017/3482 , A61B2017/3488 , A61B2017/3492 , A61M25/00 , A61M25/06 , A61M2205/587 , A61N1/0504 , A61N1/0587 , A61N1/059 , A61N1/362 , A61N1/365 , A61N1/36542 , A61N1/3655 , A61N1/36564 , A61N1/37211 , A61N1/3752
摘要： A delivery device for installing a medical device in a patient comprising a body portion having a proximal end and a distal end, the distal end having a chisel shaped tip, a receptacle disposed in the distal end of the body portion for receiving a medical device for implanting in the patient, a handle disposed at the proximal end of the body portion for facilitating advancement of the proximal end of the body portion into the patient.
摘要翻译：一种用于在患者中安装医疗装置的输送装置，包括具有近端和远端的主体部分，所述远端具有凿子形尖端，设置在主体部分的远端中的接收器，用于接收用于植入患者体内，设置在主体部分的近端处的手柄，用于促进身体部分的近端进入患者体内。

6. 发明申请

WO2016020846A1 ELECTRODE LEADS FOR USE WITH IMPLANTABLE NEUROMUSCULAR ELECTRICAL STIMULATOR 审中-公开
标题翻译：电极导线与可植入神经电刺激仪一起使用
公开(公告)号：WO2016020846A1
公开(公告)日：2016-02-11
申请号：PCT/IB2015/055926
申请日：2015-08-05
申请人： MAINSTAY MEDICAL LIMITED
发明人： SHIROFF, Jason Alan , SKUBITZ, Jason John , RAWAT, Prashant Brijmohansingh
IPC分类号： A61N1/05 , A61N1/18 , A61N1/36
CPC分类号： A61N1/05 , A61N1/0504 , A61N1/0558 , A61N1/18 , A61N1/3605
摘要： An apparatus for neuromuscular electrical stimulation is provided. The apparatus may be a stimulation lead having an elongated member made up of at least one conductor and an insulative sheath surrounding at least a portion of the conductor. A distal portion of the elongated member may include one or more electrodes and at least one fixation element to secure the one or more electrodes in or adjacent to a desired anatomical site for providing stimulation thereto. The stimulation lead has a strain relief portion on the proximal side of the one or more electrodes, configured to reduce axial forces on the distal region of the elongated member, and the effects thereof, to reduce the risk of, or even prevent, displacement of the one or more electrodes and to accommodate localized flexural motion. The apparatus also may include at least one fixation element sized and configured to be deployed between muscle layers to maintain the electrode position at the stimulation site.
摘要翻译：提供神经肌肉电刺激装置。该装置可以是具有由至少一个导体构成的细长构件和围绕导体的至少一部分的绝缘护套的刺激引线。细长构件的远侧部分可以包括一个或多个电极和至少一个固定元件，以将一个或多个电极固定在期望的解剖部位中或附近，以便向其提供刺激。刺激引线在一个或多个电极的近侧具有应变消除部分，其被构造成减小细长构件的远侧区域上的轴向力及其影响，以减少或甚至防止位移的风险一个或多个电极并且适应局部弯曲运动。该装置还可以包括至少一个固定元件，其尺寸和构造为被布置在肌肉层之间以将电极位置维持在刺激部位。

7. 发明申请

WO2015195427A1 NEEDLE HUB FOR OVER-THE-NEEDLE CATHETER 审中-公开
标题翻译：针式针头用于过针针
公开(公告)号：WO2015195427A1
公开(公告)日：2015-12-23
申请号：PCT/US2015/035047
申请日：2015-06-10
申请人： AVENT, INC.
发明人： KHALAJ, Steve Saeed
IPC分类号： A61M25/06
CPC分类号： A61M25/0097 , A61B5/4893 , A61B5/6848 , A61M25/0606 , A61N1/0502 , A61N1/0504 , A61N1/0551
摘要： The present disclosure is directed to an over-the-needle (OTN) catheter assembly having an improved needle hub. The OTN catheter assembly includes a catheter defining a lumen extending from a proximal end to a distal end. A needle having a proximal end and a distal end is configured within the lumen of the catheter. The needle hub is configured with the proximal end of the needle and includes a bore defined therethrough. The needle hub also includes at least one cavity extending from the bore to an exterior surface of the needle hub. Thus, the needle extends at least partially through the bore of the needle hub such that the needle is exposed via the cavity from the exterior surface of the needle hub so as to engage a nerve stimulator apparatus.
摘要翻译：本公开涉及具有改进的针毂的针管（OTN）导管组件。 OTN导管组件包括限定从近端延伸到远端的内腔的导管。具有近端和远端的针构造在导管的内腔内。针座配置有针的近端，并且包括由其限定的孔。针座还包括从孔延伸到针座的外表面的至少一个腔。因此，针至少部分延伸穿过针座的孔，使得针经由空腔从针座的外表面暴露以接合神经刺激器装置。

8. 发明申请

WO2015195426A1 OVER-THE-NEEDLE EXPANDABLE CATHETER 审中-公开
标题翻译：超针头可伸缩导管
公开(公告)号：WO2015195426A1
公开(公告)日：2015-12-23
申请号：PCT/US2015/035043
申请日：2015-06-10
申请人： AVENT, INC.
发明人： KHALAJ, Steve Saeed
IPC分类号： A61M25/06
CPC分类号： A61M25/0606 , A61B5/4893 , A61B5/6848 , A61M25/0023 , A61M25/005 , A61M2025/0024 , A61M2025/0175 , A61M2205/0266 , A61N1/0502 , A61N1/0504 , A61N1/0551
摘要： The present disclosure is directed to an over-the-needle (OTN) catheter assembly having an expandable catheter. More specifically, the OTN catheter assembly includes a catheter having an expandable body with a proximal end and a distal end coaxially mounted onto a needle. The body defines a lumen extending from the proximal end to the distal end. Further, the body is expandable between a compressed length and an expanded length. The needle is configured within the lumen of the catheter and has a first length. The first length is longer than the compressed length of the catheter and shorter than the expanded length of the catheter. In addition, the body of the catheter is configured to expand from the compressed length to the expanded length when heat is applied to the catheter such that the distal end of the catheter extends past a distal end of the needle.
摘要翻译：本公开涉及具有可扩张导管的针管（OTN）导管组件。更具体地说，OTN导管组件包括具有可扩张体的导管，其具有近端和远端，其同轴地安装在针上。主体限定从近端延伸到远端的内腔。此外，主体在压缩长度和扩展长度之间是可扩展的。针被配置在导管的内腔内并具有第一长度。第一长度比导管的压缩长度长，并且短于导管的扩展长度。此外，导管的主体构造成当将热量施加到导管时使其从压缩长度膨胀到扩展长度，使得导管的远端延伸穿过针的远端。

9. 发明申请

WO2015160425A1 PACING DEVICE WITH AUTONOMOUS ANTI-TACHYCARDIA PACING 审中-公开
标题翻译：具有自动抗紫杉花的PACING设备
公开(公告)号：WO2015160425A1
公开(公告)日：2015-10-22
申请号：PCT/US2015/015614
申请日：2015-02-12
申请人： CARDIAC PACEMAKERS, INC.
发明人： LUDWIG, Jacob, M.
IPC分类号： A61N1/39 , A61N1/362 , A61B5/0402
CPC分类号： A61N1/3962 , A61B5/042 , A61B5/0464 , A61B5/4836 , A61N1/0504 , A61N1/0563 , A61N1/3621 , A61N1/3622 , A61N1/3931
摘要： In an example, an apparatus is described that includes an implantable housing, a heart signal sensing circuit configured to sense intrinsic electrical heart signals, a ventricular tachyarrhythmia (VT) detector circuit, operatively coupled to the heart signal sensing circuit, the detector circuit operable to detect a VT based on the sensed heart signals, a processor configured to control delivery of an anti-tachyarrhythmia pacing (ATP) therapy based on the detected VT, and an energy delivery circuit configured to deliver the ATP therapy in response to the detected VT, wherein the apparatus does not include a shock circuit capable of delivering a therapeutically-effective cardioverting or defibrillating shock.
摘要翻译：在一个示例中，描述了一种装置，其包括可植入壳体，被配置为感测固有电气心脏信号的心脏信号感测电路，可操作地耦合到心脏信号感测电路的心室快速性心律失常（VT）检测器电路，检测器电路可操作以基于感测到的心脏信号来检测VT;处理器，被配置为基于检测到的VT控制抗心律失常起搏（ATP）治疗的递送，以及能量递送电路，其被配置为响应于检测到的VT传送ATP治疗，其中所述装置不包括能够递送治疗有效的心律转复或去颤的休克的休克回路。

10. 发明申请

WO2015060927A3 IMPLANTABLE HEAD MOUNTED NEUROSTIMULATION SYSTEM FOR HEAD PAIN 审中-公开
公开(公告)号：WO2015060927A3
公开(公告)日：2015-07-23
申请号：PCT/US2014051235
申请日：2014-08-15
申请人： SYNTILLA MEDICAL LLC
发明人： REED KENNETH LYLE , BULGER ROBERT RAYMOND
IPC分类号： A61N1/05
CPC分类号： A61N1/3787 , A61N1/0504 , A61N1/0526 , A61N1/0529 , A61N1/0551 , A61N1/36075 , A61N1/37211 , A61N1/37229 , A61N1/375
摘要： An implantable head-mounted unibody peripheral neurostimulation system is provided for implantation in the head for the purpose of treating chronic head pain, including migraine. The system may include an implantable pulse generator (IPG) from which multiple stimulating leads may extend sufficient to allow for adequate stimulation over multiple regions of the head, preferably including the frontal, parietal and occipital regions. A lead may include an extended body, along which may be disposed a plurality of surface metal electrodes, which may be sub-divided into a plurality of electrode arrays. A plurality of internal metal wires may run a portion of its length and connect the IPG's internal circuit to the surface metal electrodes. The IPG may include a rechargeable battery, an antenna, and an application specific integrated circuit. The IPG may be capable of functional connection with an external radiofrequency unit for purposes that may include recharging, diagnostic evaluation, and programming.

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