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1. 发明申请

WO2022125171A1 NON-INVASIVE BLOOD PRESSURE ESTIMATION AND BLOOD VESSEL MONITORING BASED ON PHOTOACOUSTIC PLETHYSMOGRAPHY 审中-公开
公开(公告)号：WO2022125171A1
公开(公告)日：2022-06-16
申请号：PCT/US2021/052835
申请日：2021-09-30
申请人： QUALCOMM INCORPORATED [US]/[US]
发明人： KITCHENS, Jack Conway , SCHNEIDER, John Keith , BRELOFF, Evan Michael , BROOKS, Emily Kathryn , GOJEVIC, Stephen Michael , JOHN ARCHIBALD, Fitzgerald , STOIANOV, Alexei , GORE, Shounak Uday , BUCHAN, Nicholas Ian
IPC分类号： A61B5/00 , A61B5/021 , A61B5/0285
摘要： Some disclosed methods involve controlling, via a control system, a light source system to emit a plurality of light pulses into biological tissue at a pulse repetition frequency, the biological tissue including blood and blood vessels at depths within the biological tissue. Such methods may involve receiving, by the control system, signals from the piezoelectric receiver corresponding to acoustic waves emitted from portions of the biological tissue, the acoustic waves corresponding to photoacoustic emissions from the blood and the blood vessels caused by the plurality of light pulses. Such methods may involve detecting, by the control system, heart rate waveforms in the signals, determining, by the control system, a first subset of detected heart rate waveforms corresponding to vein heart rate waveforms and determining, by the control system, a second subset of detected heart rate waveforms corresponding to artery heart rate waveforms.

2. 发明申请

WO2022030623A1 睡眠推定装置、睡眠推定システム、ウェアラブル機器、及び睡眠推定方法审中-公开
公开(公告)号：WO2022030623A1
公开(公告)日：2022-02-10
申请号：PCT/JP2021/029351
申请日：2021-08-06
申请人：京セラ株式会社 , 国立大学法人　筑波大学
发明人：阿部　高志 , 範　志偉 , 渡邉　孝浩
IPC分类号： A61B5/0285 , A61B5/11 , A61B5/16
摘要：睡眠段階を簡便に推定する。睡眠推定装置は、血流データを取得する第１取得部と、血流データに対して周波数解析処理を実行することにより、血流データの周波数スペクトルを生成する生成部と、周波数スペクトルに基づき、被検体の睡眠段階を判定する第１判定部と、を備える。

3. 发明申请

WO2021250142A1 SYSTEMS AND METHODS FOR OBTAINING A PULSE WAVE VELOCITY MEASUREMENT 审中-公开
公开(公告)号：WO2021250142A1
公开(公告)日：2021-12-16
申请号：PCT/EP2021/065551
申请日：2021-06-10
申请人： KONINKLIJKE PHILIPS N.V.
发明人： FRACKOWIAK, Bruno, Jean, François , VAN DER HORST, Arjen
IPC分类号： A61B5/02 , A61B5/021 , A61B5/0285 , A61B5/00 , A61B5/02007 , A61B5/02125 , A61B5/6852 , A61B5/7203 , A61B5/7246
摘要： The invention provides an apparatus for obtaining a pulse wave velocity measurement from a vessel of a subject. The apparatus is adapted to obtain measurement data from a vessel of a subject and an initial pulse wave velocity value. The measurement data is then separated into a forward wave component and a backward wave component, wherein the backward and forward wave components are associated with waves which propagate along the vessel in opposite directions. A final pulse wave velocity is then calculated by either: calculating a forward pulse wave velocity based on the forward wave component and determining a final pulse wave velocity measurement based on the forward pulse wave velocity; or calculating a backward pulse wave velocity based on the backward wave component and determining a final pulse wave velocity measurement based on the backward pulse wave velocity.

4. 发明申请

WO2021124071A1 IMPROVED PERSONAL HEALTH DATA COLLECTION 审中-公开
公开(公告)号：WO2021124071A1
公开(公告)日：2021-06-24
申请号：PCT/IB2020/061894
申请日：2020-12-14
申请人： LEMAN MICRO DEVICES SA
发明人： ELLIOTT, Christopher , JONES, Mark-Eric , GAWAD, Shady , KLEIN, Gabriel , CLERK, Didier , BAUSER, Phillippe
IPC分类号： A61B5/02 , A61B5/026 , A61B5/0285 , A61B5/107 , A61B5/021 , A61B5/0225 , A61B5/00 , A61B5/01 , A61B5/024 , A61B5/145 , A61B5/1455 , A61B2562/0209 , A61B2562/0219 , A61B2562/0233 , A61B2562/0247 , A61B5/0008 , A61B5/0053 , A61B5/02007 , A61B5/02035 , A61B5/02116 , A61B5/02125 , A61B5/02255 , A61B5/02433 , A61B5/02438 , A61B5/0261 , A61B5/1079 , A61B5/14542 , A61B5/14552 , A61B5/349 , A61B5/486 , A61B5/6844 , A61B5/6898 , A61B5/7207 , A61B5/7267 , A61B5/7278
摘要： The invention disclosed herein relates to improvements in the collection personal health data. It further relates to a Personal Health Monitor (PHM), which may be a Personal Hand Held Monitor (PHHM), that incorporates a Signal Acquisition Device (SAD) and a processor with its attendant screen and other peripherals. The SAD is adapted to acquire signals which can be used to derive one or more measurements of parameters related to the health of a user. The computing and other facilities of the PHM with which the SAD is integrated are adapted to control and analyse signals received from the SAD. The personal health data collected by the SAD may include data related to one or more of blood pressure, pulse rate, blood oxygen level (SpO2), body temperature, respiration rate, ECG, cardiac output, heart function timing, arterial stiffness, tissue stiffness, hydration, blood viscosity, blood pressure variability, the concentration of constituents of the blood such as glucose or alcohol and the identity of the user.

5. 发明申请

WO2020126337A2 INTEGRATED BIOSENSING SYSTEMS 审中-公开
公开(公告)号：WO2020126337A2
公开(公告)日：2020-06-25
申请号：PCT/EP2019/082484
申请日：2019-11-25
申请人： AMS AG
发明人： GRUBER, Bernhard , PAURITSCH, Manfred , DEDEK, Martin
IPC分类号： A61B5/026 , A61B5/0285
摘要： An integrated sensing system for characterizing blood flow in a subject includes a light source assembly including a light source configured to emit light of a particular wavelength. The integrated sensing system includes an integrated circuit electrically connected to the light source assembly. The integrated circuit includes a light detector assembly including multiple light detectors configured to detect light of the particular wavelength; and a correlator configured to determining a delay between optical signals detected by respective light detectors of the light detector assembly.

6. 发明申请

WO2019013418A1 혈류의 물리량 산출 방법 및 장치 审中-公开
公开(公告)号：WO2019013418A1
公开(公告)日：2019-01-17
申请号：PCT/KR2018/000722
申请日：2018-01-16
申请人： 사회복지법인 삼성생명공익재단 , 고려대학교 산학협력단
发明人： 문영준 , 한창균 , 박승우
IPC分类号： A61B5/0285 , A61B5/00
摘要： 본 발명의 일 실시예에 따른 혈류의 제1 방향으로의 속도 정보로부터 상기 혈류(血流)의 적어도 하나의 물리량(物理量)을 산출하는 방법은, 대상체 내의 각 지점에서 혈류의 제1 방향으로의 속도 정보를 포함하는 제1 데이터 및 상기 대상체의 외경계선의 위치 정보를 획득하는 단계; 상기 대상체 내의 어느 하나의 지점에서의 혈류의 제1 방향으로의 속도와 상기 어느 하나의 지점과 인접하는 적어도 하나의 지점에서의 혈류의 제1 방향으로의 속도들이 제1 방향으로의 속도를 높이값으로 하는 3차원 공간상에서 연속하는 곡면을 형성하도록 상기 제1 데이터를 보정하여 제4 데이터를 생성하는 단계; 상기 대상체 내의 어느 하나의 지점에서의 혈류의 제1 방향으로의 속도와 상기 어느 하나의 지점과 인접하는 적어도 하나의 지점에서의 혈류의 제1 방향으로의 속도들에 의해 형성되는 파동에서 기 설정된 주파수 이상의 주파수 성분이 제거되도록 제4 데이터를 보정하여 제5 데이터를 생성하는 단계; 및 상기 제5 데이터 및 상기 대상체의 외경계선의 위치 정보에 기초하여 상기 혈류의 제2 방향으로의 속도를 산출하는 단계;를 포함 할 수 있다.

7. 发明申请

WO2019002670A1 METHODS, APPARATUS, COMPUTER PROGRAMS, SYSTEMS FOR CALCULATING A PULSE WAVE VELOCITY OF A SUBJECT 审中-公开
公开(公告)号：WO2019002670A1
公开(公告)日：2019-01-03
申请号：PCT/FI2018/050451
申请日：2018-06-13
申请人： NOKIA TECHNOLOGIES OY
发明人： SALO, Antti Oskari , BLOMQVIST, Kim , RAJALA, Satu
IPC分类号： A61B5/021 , A61B5/02 , A61B5/00 , A61B5/024 , A61B5/0285 , A61B5/0295 , A61B5/11
CPC分类号： A61B5/02125 , A61B5/02007 , A61B5/02416 , A61B5/0285 , A61B5/0295 , A61B5/1102 , A61B5/1113 , A61B5/6892
摘要： A method comprising: determining a time difference between detecting a heart-related signal of a subject and detecting a vasculature signal of the subject at a first one of a plurality of distributed sensors; using a controller to automatically estimate an in-vivo distance from the heart of the subject to the first one of the plurality of sensors in dependence upon a determined unconstrained body position of the subject; and calculating a pulse wave velocity.

8. 发明申请

WO2018136656A1 NON-INVASIVE BLOOD PRESSURE MEASUREMENT USING PULSE WAVE VELOCITY 审中-公开
公开(公告)号：WO2018136656A1
公开(公告)日：2018-07-26
申请号：PCT/US2018/014273
申请日：2018-01-18
申请人： STRYKER CORPORATION
发明人： SIEDENBURG, Clinton, T.
IPC分类号： A61B5/021 , A61B8/06 , A61B5/0285 , A61H31/00
摘要： A method and apparatus to non-invasively measure instantaneous blood pressure using pulse wave velocity are disclosed. A measurement component is affixed to a patient proximate to a blood vessel. One or more sensors, such as an ultrasound sensor, is included in the measurement component. The measurement component substantially simultaneously measures the pulse wave velocity of the vessel and the instantaneous blood velocity within the vessel. The measurement component computes the instantaneous blood pressure of the vessel using, for example, the water hammer equation. The one or more sensors may be contained in a disposable patch or collocated with another sensor, such as a patient-monitor sensor, or the like.

9. 发明申请

WO2018132526A1 PAIN MANAGEMENT BASED ON CARDIOVASCULAR PARAMETERS 审中-公开
公开(公告)号：WO2018132526A1
公开(公告)日：2018-07-19
申请号：PCT/US2018/013251
申请日：2018-01-11
申请人： BOSTON SCIENTIFIC NEUROMODULATION CORPORATION
发明人： SRIVASTAVA, Kyle Harish , THAKUR, Pramodsingh Hirasingh , ANNONI, Elizabeth M. , GU, Jianwen , CLARK, Bryan Allen , KILMAR, Thomas Gaviao
IPC分类号： A61B5/021 , A61B5/0456 , A61B5/00 , A61B5/0285 , A61B5/029
摘要： This document discusses, among other things, systems and methods for managing pain in a subject. A system may include a sensor circuit configured to sense one or more physiological signals. A pain analyzer circuit may generate from the physiological signals cardiovascular parameters indicative of arterial pulsatile activity or cardiac electrical activity, and generate a pain score using at least the cardiovascular parameters. The system may include a neurostimulator that can adaptively control the delivery of pain therapy by adjusting stimulation parameters based on the pain score.

10. 发明申请

WO2017218818A3 METHOD FOR ELIMINATING NOISE IN SIGNAL DATA FROM A PIEZOELECTRIC DEVICE AND DETECTING STENOSIS 审中-公开
公开(公告)号：WO2017218818A3
公开(公告)日：2017-12-21
申请号：PCT/US2017/037744
申请日：2017-07-07
申请人： CVR GLOBAL, INC.
发明人： KLINE, Bret , BAKEMA, Peter , TRUONG, Young , FINLAYSON, Richard , DAY, Orville
IPC分类号： A61B5/0285 , A61B7/04
摘要： A method for eliminating noise from a data sample comprising passive noise cancellation, active noise cancellation, and a software based filtering process; said passive noise cancellation comprises collecting data from a piezo sensor that is sound isolated by a noise attenuating material surrounding said piezo sensor and forming a connection to the surface to be sampled; isolating said piezo sensor on a device comprising a membrane; said active noise cancellation comprises utilizing a second sensor adjacent to said piezo sensor to detect ambient sounds and subtracting said ambient sounds detected from said second sensor from said data; performing a wavelet analysis on said data; and performing a method selected from the group consisting Burg's method, Welch's method, and combinations thereof.

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