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    • 1. 发明申请
    • AN IMPROVEMENT ON IP FRAGMENTATION IN GTP TUNNEL
    • GTP隧道知识产权分类改进
    • WO2012083482A1
    • 2012-06-28
    • PCT/CN2010/002102
    • 2010-12-21
    • TELEFONAKTIEBOLAGET L M ERICSSON (PUBL)GU, WeiGUO, LeiLI, XiaoLIU, DiSUN, LirongXIA, Qi
    • GU, WeiGUO, LeiLI, XiaoLIU, DiSUN, LirongXIA, Qi
    • H04L12/56
    • H04L45/74H04L47/36H04W28/06H04W76/12H04W80/04
    • The present invention relates to a method for improving IP fragmentation and transmission of user payload between a User Equipment, UE (10), and a Peer Node, PN (14). The payload is transmitted through a transmission path enabled by at least a first (17,18) and a second (17,18) established tunnel, said tunnels connecting a first (11), (13) and a second (11, 13) node in a Packet Core Network, PCN. The method comprises the steps of: - The first node (11,13) fragments (19) at least one received payload packet (15) into fragments (16) on the basis of a minimum Maximum Transmission Unit, MTU, for an upper IP layer of the transmission path. - The first node (11,13) encapsulates (20) said fragments at the entry of the first tunnel (17, 18). What particularly characterizes the method is that it further comprises a step where the first node (11,13) determines (21) the MTU for the upper IP layer of the transmission path on the basis of an MTU of a lower IP layer of the transmission path and on the basis of the size of at least one additional tunnel header for the encapsulated fragments (16).
    • 本发明涉及一种用于改善用户设备,UE(10)和对等节点(PN)(14)之间的用户有效载荷的IP分段和传输的方法。 有效载荷通过至少第一(17,18)和第二(17,18)建立的隧道启用的传输路径传输,所述隧道连接第一(11),(13)和第二(11,13) 分组核心网络中的节点,PCN。 该方法包括以下步骤: - 第一节点(11,13)根据用于较高IP的最小最大传输单元MTU将至少一个接收到的有效载荷分组(15)分段(19)成片段(16) 传输路径层。 - 第一节点(11,13)在第一隧道(17,18)的入口处封装(20)所述片段。 该方法的特征在于,其还包括步骤,其中第一节点(11,13)基于传输的较低IP层的MTU来确定(21)传输路径的上层IP的MTU 并且基于用于封装的片段(16)的至少一个附加隧道头部的大小。
    • 3. 发明申请
    • DIMMER CONTROL LEAKAGE PULL DOWN USING MAIN POWER DEVICE IN FLYBACK CONVERTER
    • 使用主电源设备在闪回转换器中使用DIMMER控制漏电
    • WO2010068568A1
    • 2010-06-17
    • PCT/US2009/066861
    • 2009-12-04
    • LINEAR TECHNOLOGY CORPORATIONNEGRETE, Michael, GeorgeGU, Wei
    • NEGRETE, Michael, GeorgeGU, Wei
    • G05F1/00H05B37/02
    • H05B33/0845H05B33/0815Y02B20/346Y02B20/347
    • A flyback controller may include a dimmer input configured to receive a chopped and rectified AC voltage Each cycle of the signal may have an off period which is substantially attenuated but not always zero due to leakage of a dimmer control from which the chopped AC voltage originates, and an on period which substantially tracks the AC voltage The flyback controller may include a control circuit configured to generate a switching signal based on the signal from the dimmer input The switching signal may controllably oscillate between its on and off states during the on periods of the chopped and rectified AC voltage The switching signal may be in the on state during the off periods of the chopped and rectified AC voltage, thereby preventing a voltage build up from the dimmer control leakage
    • 回扫控制器可以包括被配置为接收切断和整流的AC电压的调光器输入。由于来自切断的AC电压的调光器控制的泄漏,信号的每个周期可以具有基本衰减但不总是为零的关闭周期, 以及基本跟踪AC电压的导通周期。反激控制器可以包括被配置为基于来自调光器输入的信号产生开关信号的控制电路。开关信号可以在该开关信号的接通时段期间可控制地在其导通和截止状态之间振荡 斩波和整流的交流电压切断信号在斩波和整流交流电压的关闭期间可能处于导通状态,从而防止由调光器控制泄漏的电压积聚
    • 5. 发明申请
    • ARF-BP1 AS MEDIATOR OF P53-DEPENDENT AND INDEPENDENT TUMOR SUPPRESSION AND USES THEREOF
    • ARF-BP1作为P53依赖和独立肿瘤抑制的治疗方法及其用途
    • WO2006031928A2
    • 2006-03-23
    • PCT/US2005/032835
    • 2005-09-15
    • THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OFNEW YORKGU, Wei
    • GU, Wei
    • C12Q1/68G01N33/574C07H21/04C12P21/06C12N9/64
    • G01N33/57496C07K14/4747C12N9/93
    • The present invention relates to the mechanism of ARF-mediated cell growth suppression. ARF-BP1 is identified as a novel ubiquitin ligase, and a major component of ARF-containing nuclear complexes in human cells. The present invention discloses a novel mechanism of ARF-mediated p53 activation and that ARF-BP1 is a critical mediator of both p53-independent and p53-dependent tumor suppression functions of ARF. Inactivation of ARF-BP1 in normal cells stabilizes p53 and induces p53-dependent apoptosis. Inactivation of ARF-BP1, but not Mdm2, in p53-wildtype cells promotes cell growth inhibition in a manner reminiscent of ARF induction. ARF-BP1 directly binds and ubiquitinates p53 and inactivation of endogenous ARF-BP1 is crucial for ARF-mediated p53 stabilization in Mdm2-null cells. ARF-BP1 is advantageous over Mdm2 as a target for suppressing tumor cell growth regardless of p53 status.
    • 本发明涉及ARF介导的细胞生长抑制机理。 ARF-BP1被鉴定为新型泛素连接酶,是人类细胞中含有ARF的核配合物的主要成分。 本发明公开了ARF介导的p53活化的新机制,ARF-BP1是ARF的p53非依赖性和p53依赖性肿瘤抑制功能的关键介质。 正常细胞中ARF-BP1的失活使p53稳定并诱导p53依赖性细胞凋亡。 在p53野生型细胞中ARF-BP1而不是Mdm2的失活以令人联想到ARF诱导的方式促进细胞生长抑制。 ARF-BP1直接结合和泛素化p53,并且内源性ARF-BP1的失活对于在Mdm2-null细胞中的ARF介导的p53稳定是至关重要的。 ARF-BP1优于Mdm2作为抑制肿瘤细胞生长而不管p53状态如何的靶标。
    • 10. 发明申请
    • BATTERY OPERATED RAZOR
    • 电池操作RAZOR
    • WO2014067118A1
    • 2014-05-08
    • PCT/CN2012/083919
    • 2012-11-01
    • THE GILLETTE COMPANYREHBEIN, StefanSHEN, GuohuaGU, WeiSCHNAK, Fred DieterROENNEBERG, Gerrit
    • REHBEIN, StefanSHEN, GuohuaGU, WeiSCHNAK, Fred DieterROENNEBERG, Gerrit
    • B26B21/38
    • B26B21/526B26B21/222
    • Handle (10) is provided for battery (38) operated razors. In some implementations, the handle (10) includes a simple, efficient mechanism for both securing a battery cover (16) to the handle (10) of a razor and at the same time providing a high reliability electrical contact between the battery (38) and electronics of the razor. The mechanism includes a closing system including a first conductive component (50) slidably attached within the battery cover (16) and biased toward a predetermined axial position, and a second conductive component (80) secured to the interior wall of the grip portion. The first conductive component (50) is configured to interact with the second conductive component (80) and move axially within the battery cover (16) during engagement of the battery cover (16) with the grip portion.
    • 手柄(10)用于电池(38)操作的剃须刀。 在一些实施方案中,手柄(10)包括用于将电池盖(16)固定到剃刀的手柄(10)的简单有效的机构,并且同时在电池(38)之间提供高可靠性的电接触, 和剃须刀的电子产品。 该机构包括闭合系统,该闭合系统包括可滑动地附接在电池盖(16)内并朝向预定的轴向位置偏压的第一导电部件(50)和固定到把手部分的内壁上的第二导电部件(80)。 第一导电部件(50)构造成在电池盖(16)与把手部分接合期间与第二导电部件(80)相互作用并在电池盖(16)内轴向移动。