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1. 发明申请

WO2017158592A2 APPARATUS AND METHODS FOR USE WITH SKELETAL PROCEDURES 审中-公开
标题翻译：用于骨骼手术的装置和方法
公开(公告)号：WO2017158592A2
公开(公告)日：2017-09-21
申请号：PCT/IL2017/050314
申请日：2017-03-13
申请人： TOLKOWSKY, David
发明人： TOLKOWSKY, David
IPC分类号： A61B6/12 , A61B6/00 , A61B17/17 , A61B17/56 , A61B17/34 , A61B34/20 , A61B90/00 , A61B8/00 , G06T7/00 , G06T7/73

2. 发明申请

WO2012014212A3 CO-USE OF ENDOLUMINAL DATA AND EXTRALUMINAL IMAGING 审中-公开
公开(公告)号：WO2012014212A3
公开(公告)日：2012-02-02
申请号：PCT/IL2011/000612
申请日：2011-07-28
申请人： SYNC-RX, LTD. , TOLKOWSKY, David , COHEN, Ran , KLAIMAN, Eldad , BARZELAY, Zohar , STEINBERG, Alexander , PHILIPP, Sagiv
发明人： TOLKOWSKY, David , COHEN, Ran , KLAIMAN, Eldad , BARZELAY, Zohar , STEINBERG, Alexander , PHILIPP, Sagiv
IPC分类号： G06K9/00
摘要： Apparatus and methods are provided for use with an endoluminal data-acquisition device (31) that acquires a set of endoluminal data-points of a lumen of a subject's body at respective locations inside the lumen, a second endoluminal device, and a display configured to display images. At least one processor includes location-association functionality that associates a given data point acquired by the endoluminal data-acquisition device with a given location within the lumen. Location-determination functionality determines, by means of image processing, in an extraluminal image of the second endoluminal device, a current location of at least a portion of the second endoluminal device. Display-driving functionality drives the display to display an indication of the endoluminal data point associated with the location, in response to determining that the portion of the second device is currently at the location. Other applications are also described.

3. 发明申请

WO2008107905A2 IMAGING AND TOOLS FOR USE WITH MOVING ORGANS 审中-公开
标题翻译：使用移动机器的成像和工具
公开(公告)号：WO2008107905A2
公开(公告)日：2008-09-12
申请号：PCT/IL2008/000316
申请日：2008-03-09
申请人： SYNC-RX, LTD. , IDDAN, Gavriel , TOLKOWSKY, David
发明人： IDDAN, Gavriel , TOLKOWSKY, David
IPC分类号： A61B5/05 , A61F2/84 , A61B17/22
CPC分类号： A61M5/007 , A61B5/02007 , A61B5/4836 , A61B5/7289 , A61B6/12 , A61B6/503 , A61B6/504 , A61B6/5217 , A61B6/541 , A61B8/0883 , A61B8/0891 , A61B8/543 , A61B17/3207 , A61B18/1492 , A61B90/37 , A61B2017/00252 , A61B2017/00694 , A61B2017/00703 , A61B2017/22044 , A61B2017/22094 , A61B2090/3735 , A61B2090/3762 , A61B2090/3782 , A61B2576/02 , A61F2/958 , A61M2210/12
摘要： Apparatus is described for use with a portion of a subject's body that moves as a result of cyclic activity of a body system. An imaging device (11) acquires a plurality of image frames of the portion. A sensor (12) senses a phase of the cyclic activity. A medical tool (67) performs a function with respect to the portion. A control unit (63) generates a stabilized set of image frames of the medical tool disposed within the portion, actuates the tool to perform the function or move, in response to the sensor sensing that the cyclic activity is at a given phase thereof, and inhibits the tool from performing the action or moving in response to the sensor sensing that the cyclic activity is not at the given phase. A display (15) facilitates use of the tool by displaying the stabilized set of image frames.
摘要翻译：描述了与身体系统的循环活动结果一起移动的受试者身体的一部分使用的装置。成像装置（11）获取该部分的多个图像帧。传感器（12）感测循环活动的相位。医疗工具（67）相对于该部分执行功能。控制单元（63）响应于传感器感测到循环活动处于给定阶段而产生设置在该部分内的医疗工具的稳定化的一组图像帧，以启动工具来执行功能或移动，以及禁止工具执行动作或响应于传感器检测到循环活动不在给定阶段而移动。显示器（15）通过显示稳定的一组图像帧来便于使用该工具。

4. 发明申请

WO2008107905A3 IMAGING AND TOOLS FOR USE WITH MOVING ORGANS 审中-公开
标题翻译：使用移动机器的成像和工具
公开(公告)号：WO2008107905A3
公开(公告)日：2010-02-18
申请号：PCT/IL2008000316
申请日：2008-03-09
申请人： SYNC RX LTD , IDDAN GAVRIEL , TOLKOWSKY DAVID
发明人： IDDAN GAVRIEL , TOLKOWSKY DAVID
IPC分类号： A61B1/00
CPC分类号： A61M5/007 , A61B5/02007 , A61B5/4836 , A61B5/7289 , A61B6/12 , A61B6/503 , A61B6/504 , A61B6/5217 , A61B6/541 , A61B8/0883 , A61B8/0891 , A61B8/543 , A61B17/3207 , A61B18/1492 , A61B90/37 , A61B2017/00252 , A61B2017/00694 , A61B2017/00703 , A61B2017/22044 , A61B2017/22094 , A61B2090/3735 , A61B2090/3762 , A61B2090/3782 , A61B2576/02 , A61F2/958 , A61M2210/12
摘要： Apparatus is described for use with a portion of a subject's body that moves as a result of cyclic activity of a body system. An imaging device (11) acquires a plurality of image frames of the portion. A sensor (12) senses a phase of the cyclic activity. A medical tool (67) performs a function with respect to the portion. A control unit (63) generates a stabilized set of image frames of the medical tool disposed within the portion, actuates the tool to perform the function or move, in response to the sensor sensing that the cyclic activity is at a given phase thereof, and inhibits the tool from performing the action or moving in response to the sensor sensing that the cyclic activity is not at the given phase. A display (15) facilitates use of the tool by displaying the stabilized set of image frames.
摘要翻译：描述了与身体系统的循环活动结果一起移动的受试者身体的一部分使用的装置。成像装置（11）获取该部分的多个图像帧。传感器（12）感测循环活动的相位。医疗工具（67）相对于该部分执行功能。控制单元（63）响应于传感器感测到循环活动处于给定阶段而产生设置在该部分内的医疗工具的稳定化的一组图像帧，以启动工具执行功能或移动，以及禁止工具执行动作或响应于传感器检测到循环活动不在给定阶段而移动。显示器（15）通过显示稳定的一组图像帧来便于使用该工具。

5. 发明申请

WO2009153794A1 STEPWISE ADVANCEMENT OF A MEDICAL TOOL 审中-公开
标题翻译：医疗工具的步骤推进
公开(公告)号：WO2009153794A1
公开(公告)日：2009-12-23
申请号：PCT/IL2009/000610
申请日：2009-06-18
申请人： SYNC-RX, LTD. , IDDAN, Gavriel , TOLKOWSKY, David , COHEN, Ran , BLANK, Jacob
发明人： IDDAN, Gavriel , TOLKOWSKY, David , COHEN, Ran , BLANK, Jacob
IPC分类号： A61M25/01
CPC分类号： A61B5/06 , A61B6/503 , A61B6/5217 , A61B6/541 , A61B8/02 , A61B2017/00252 , A61B2017/00694 , A61B2017/00703 , A61B2017/22044 , A61B2017/22094 , A61F2/958 , A61F2002/9517 , A61M25/09041 , A61M2025/09116
摘要： Apparatus is provided, including a sensor for sensing a phase of cyclic activity of a body system of the subject. A tool modulator of the apparatus includes a gate configured: in a first cycle of the cyclic activity, to allow movement of a tool, in response to the cyclic activity being at a first given phase thereof, following the given phase in the first cycle and prior to an occurrence of the given phase in a subsequent cycle of the cyclic activity, to inhibit the movement of the tool, and in a second cycle of the cyclic activity, subsequent to the inhibiting of the movement, to allow movement of the tool, in response to the second cycle of the cyclic activity being at the given phase thereof. An accumulation facilitator facilitates an accumulation of the tool in the tool modulator, and/or an accumulation of energy in the tool.
摘要翻译：提供了一种装置，包括用于感测对象的身体系统的循环活动的相位的传感器。该装置的工具调制器包括：门，其配置为：在循环活动的第一周期中，响应于循环活动处于其第一给定阶段，允许工具移动，遵循第一周期中的给定阶段，以及在循环活动的随后循环中发生给定阶段之前，为了抑制工具的移动，并且在循环活动的第二循环中，在阻止运动之后，允许工具移动，响应于循环活性在其给定阶段的第二循环。累积促进器促进工具在工具调制器中的积累和/或能量在工具中的累积。

6. 发明申请

WO2008111070A2 DEVICES AND METHODS FOR PERFORMING MEDICAL PROCEDURES IN TREE-LIKE LUMINAL STRUCTURES 审中-公开
标题翻译：用于在树状结构中执行医疗程序的设备和方法
公开(公告)号：WO2008111070A2
公开(公告)日：2008-09-18
申请号：PCT/IL2008000344
申请日：2008-03-12
申请人： TOLKOWSKY DAVID
发明人： TOLKOWSKY DAVID
IPC分类号： A61B8/00
CPC分类号： A61B5/066 , A61B1/0052 , A61B1/018 , A61B1/2676 , A61B5/064 , A61B5/7285 , A61B5/742 , A61B6/03 , A61B6/466 , A61B6/5247 , A61B6/541 , A61B8/12 , A61B8/4254 , A61B8/5238 , A61B8/543 , A61B17/00491 , A61B17/12104 , A61B17/12159 , A61B34/20 , A61B90/36 , A61B90/361 , A61B2017/1205 , A61B2034/105 , A61B2034/2051 , A61B2090/364 , A61B2090/365 , A61B2090/3735 , A61B2090/378
摘要： Apparatus is described for use with an imaging device (31) that acquires a pre-procedure image of a portion of a subject's body disposed at a pre-procedure position. An input unit receives from a user an indication of two or more lines within the image that correspond to respective branches of a multi-branch luminal structure. A probe (1) moves within the portion along two or more lines in the structure that respectively correspond to the two or more lines within the image. A location sensor (18) coupled to the probe senses location coordinates along the two or more lines, while the portion is at a current position. A control unit (34) registers the image of the portion with the portion's current position by registering (a) the two or more lines within the image, with (b) the location coordinates along the two or more lines. Other embodiments are also described.
摘要翻译：描述了与成像装置（31）一起使用的装置，该成像装置（31）获取被布置在预处理位置的对象身体的一部分的预过程图像。输入单元从用户接收对应于多分支管腔结构的相应分支的图像内的两行或更多行的指示。探针（1）在该结构内沿着分别对应于图像内的两条或更多条线的两条或多条线的部分内移动。耦合到探头的位置传感器（18）感测沿着两条或更多条线的位置坐标，同时该部分处于当前位置。控制单元（34）通过在（b）沿着两条或更多条线的位置坐标登记（a）图像中的两条或更多条线来将该部分的图像登记该部分的当前位置。还描述了其它实施例。

7. 发明申请

WO2013175472A2 CO-USE OF ENDOLUMINAL DATA AND EXTRALUMINAL IMAGING 审中-公开
标题翻译：共同使用内皮细胞数据和超声成像
公开(公告)号：WO2013175472A2
公开(公告)日：2013-11-28
申请号：PCT/IL2013/050438
申请日：2013-05-21
申请人： SYNC-RX, LTD. , STEINBERG, Alexander , KLAIMAN, Eldad , COHEN, Ran , TOLKOWSKY, David , BARZELAY, Zohar
发明人： STEINBERG, Alexander , KLAIMAN, Eldad , COHEN, Ran , TOLKOWSKY, David , BARZELAY, Zohar
IPC分类号： A61B1/05
CPC分类号： A61B1/04 , A61B1/05 , A61B5/066 , A61B6/12 , A61B6/463 , A61B6/487 , A61B6/504 , A61B6/5235 , A61B6/5247 , A61B6/541 , A61B8/0841 , G06T7/73 , G06T2207/10068 , G06T2207/10121 , G06T2207/30101
摘要： Apparatus and methods are described including a processor (20) configured to receive first and second sets of extraluminal images of a lumen, the second set being acquired while an endoluminal device is being moved through the lumen. The processor designates at least one of the first set of images as a roadmap image, and designates, within the lumen in the roadmap image, a roadmap pathway (42). A plurality of features (44, 46, 48, 50) that are visible within at least some of the second set of extraluminal images are identified, and an arrangement of three or more of the features within the image are compared to a shape of at least a portion of the roadmap pathway. Based upon the comparing, the identified features are mapped to locations along the roadmap pathway within the roadmap image. Other applications are also described.
摘要翻译：描述了包括处理器（20）的装置和方法，所述处理器（20）被配置为接收管腔的第一组和第二组管腔外图像，所述第二组是在腔内装置移动通过所述内腔时获取的。处理器将第一组图像中的至少一个指定为路线图图像，并在路线图像图像的内腔内指定路线图路径（42）。识别在第二组外部图像中的至少一些中可见的多个特征（44,46,48,50），并且将图像中的三个或更多个特征的布置与图像的形状进行比较路线图路线的至少一部分。基于比较，所识别的特征被映射到路线图中的路线图路径上的位置。还描述了其它应用。

8. 发明申请

WO2012176191A1 LUMINAL BACKGROUND CLEANING 审中-公开
标题翻译：白色背景清洁
公开(公告)号：WO2012176191A1
公开(公告)日：2012-12-27
申请号：PCT/IL2012/000246
申请日：2012-06-21
申请人： SYNC-RX, LTD. , BARZELAY, Zohar , COHEN, Ran , TOLKOWSKY, David
发明人： BARZELAY, Zohar , COHEN, Ran , TOLKOWSKY, David
IPC分类号： A61B5/055
CPC分类号： G06T5/001 , A61B6/481 , A61B6/504 , A61B6/52 , A61B6/5235 , A61B6/5258 , G06T5/009 , G06T5/50 , G06T2207/10116 , G06T2207/20212 , G06T2207/30101
摘要： Apparatus and methods are described for use with an input angiogram image of a device inserted inside a portion of subject's body, the angiogram image being acquired in the presence of contrast agent. At least one processor (11) includes background-image-generation functionality (13) configured to generate a background image in which a relative value is assigned to a first pixel with respect to a second pixel, at least partially based upon relative values of surroundings of the first pixel and the surroundings of the second pixel in the input image. Cleaned-image-generation functionality (14) generates a cleaned image in which visibility of the radiopaque portions of the device is increased relative to the input image, by dividing the input image by the background image. Output-generation functionality (15) drives a display (16) to display an output based upon the cleaned image. Other applications are also described.
摘要翻译：描述了与插入受试者身体的一部分内的装置的输入血管造影图像一起使用的装置和方法，在存在造影剂的情况下获取血管造影图像。至少一个处理器（11）包括背景图像生成功能（13），其被配置为生成背景图像，其中相对于第二像素将相对值分配给第一像素，至少部分地基于周围环境的相对值的第一像素和第二像素的周围。清洁图像生成功能（14）通过将输入图像除以背景图像来生成其中相对于输入图像增加设备的不透射线部分的可视性的清洁图像。输出产生功能（15）驱动显示器（16）以基于清洁的图像显示输出。还描述了其它应用。

9. 发明申请

WO2010058398A3 IMAGE PROCESSING AND TOOL ACTUATION FOR MEDICAL PROCEDURES 审中-公开
标题翻译：医疗程序的图像处理和工具激励
公开(公告)号：WO2010058398A3
公开(公告)日：2010-07-22
申请号：PCT/IL2009001089
申请日：2009-11-18
申请人： SYNC RX LTD , COHEN RAN , STEINBERG ALEXANDER , PHILIPP SAGIV , TOLKOWSKY DAVID , KLAIMAN ELDAD , BLANK JACOB
发明人： COHEN RAN , STEINBERG ALEXANDER , PHILIPP SAGIV , TOLKOWSKY DAVID , KLAIMAN ELDAD , BLANK JACOB
IPC分类号： G06K9/40
CPC分类号： A61B5/0044 , A61B5/7285 , A61B5/7289 , A61B6/12 , A61B6/469 , A61B6/481 , A61B6/501 , A61B6/503 , A61B6/504 , A61B6/5217 , A61B6/5247 , A61B6/541 , A61B8/0883 , A61B8/0891 , A61B8/543 , A61B17/12036 , A61B17/1204 , A61B17/12136 , A61B18/02 , A61B18/1492 , A61B18/24 , A61B34/10 , A61B34/20 , A61B34/25 , A61B2017/00252 , A61B2017/00694 , A61B2017/00703 , A61B2017/1205 , A61B2017/22044 , A61B2017/22094 , A61B2034/105 , A61B2034/107 , A61B2034/254 , A61B2090/365 , A61F2/958 , G06K9/00369 , G06K2209/057 , G06T5/001 , G06T7/0012 , G06T7/0014 , G06T7/13 , G06T7/246 , G06T7/62 , G06T11/60 , G06T2207/10121 , G06T2207/30048 , G06T2207/30101
摘要： Apparatus and methods are provided for receiving into at least one processor a set of images of blood vessels of a subject. A road map of the subject's blood vessels is generated, by automatically (a) deriving at least one image from the set of images of the blood vessels, based upon visibility of at least a portion of the blood vessels in the set of images, and (b) in the derived image, determining a location of edge lines (24) of at least some of the portion of the blood vessels in the image. An output is generated by the processor, based on the road map. Other applications are also described.
摘要翻译：提供了用于将至少一个处理器接收对象血管的一组图像的设备和方法。通过自动地（a）基于该组图像中的血管的至少一部分的可见性从该组血管图像中导出至少一个图像，来生成该对象的血管的路线图，以及（b）在所述导出的图像中，确定所述图像中的所述血管的所述部分中的至少一些的边缘线（24）的位置。输出由处理器根据路线图生成。其他应用也被描述。

10. 发明申请

WO0117579A3 Steering configuration for catheter with rigid distal device 审中-公开
标题翻译：具有刚性远端装置的导管的转向结构
公开(公告)号：WO0117579A3
公开(公告)日：2001-08-02
申请号：PCT/IL0000537
申请日：2000-09-07
申请人： GILBOA PINHAS , TOLKOWSKY DAVID , BLECHER DANNY , SUPER DIMENSION LTD
发明人： GILBOA PINHAS , TOLKOWSKY DAVID , BLECHER DANNY
IPC分类号： A61M25/01 , A61M25/08
CPC分类号： A61M25/0144 , A61M25/0147
摘要： A steering configuration for facilitating steering of a catheter or the like provided with a rigid distal device (1000) employs a flexible support element (230) to which a rigid device (1000) is attached at its distal end. At least one elongated flexible control element (150) is configured such that tension applied to the control element (150) causes flexing of the flexible support element (230). The control element (150) is directly attached to the rigid device (1000), thereby rendering the rigid device (1000) an operative extension of the steering mechanism.

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