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1. 发明申请

WO2018226643A1 METHODS AND DEVICES FOR TREATING PANCREATITIS 审中-公开
公开(公告)号：WO2018226643A1
公开(公告)日：2018-12-13
申请号：PCT/US2018/035985
申请日：2018-06-05
申请人： UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
发明人： GITTES, George K.
IPC分类号： A61B1/00 , A61B17/00 , A61B17/12 , A61M25/00 , A61M25/01 , A61M25/09
CPC分类号： A61B17/12131 , A61B1/00098 , A61B1/00177 , A61B1/05 , A61B1/0615 , A61B17/12099 , A61B17/12136 , A61B17/12159 , A61B17/12172 , A61B17/12177 , A61B2017/0034 , A61B2017/00818 , A61B2017/00876 , A61B2017/00898 , A61B2217/005
摘要： Disclosed herein are methods and devices for treating pancreatitis. In the methods described herein, the distal portion of a catheter is routed into the pancreatic duct. The catheter delivers to the pancreatic duct an effective amount of a composition at an effective infusion pressure, wherein the amount and infusion pressure of the composition are effective to decrease the secretion of digestive enzymes from one or more exocrine tissues of the pancreas. The reduction of digestive enzymes may reduce damage to the islet cells typically seen in chronic pancreatitis. Backflow of the composition out of the pancreatic duct is limited, for example, by an occluding system, and aspiration system, or both.

2. 发明申请

WO2016161344A1 SYSTEMS AND METHODS FOR DELIVERY OF GEL EMBOLICS 审中-公开
标题翻译：用于输送凝胶的系统和方法
公开(公告)号：WO2016161344A1
公开(公告)日：2016-10-06
申请号：PCT/US2016/025669
申请日：2016-04-01
申请人： BOSTON SCIENTIFIC SCIMED, INC. , CONNOLLY, Joseph Michael , PEDERSON, Gary John Jr. , ANDERSON, Mary-Claire , HAVERKOST, Patrick A. , RAAB, David , SMITH, Mark
发明人： CONNOLLY, Joseph Michael , PEDERSON, Gary John Jr. , ANDERSON, Mary-Claire , HAVERKOST, Patrick A. , RAAB, David , SMITH, Mark
IPC分类号： A61B17/12
CPC分类号： A61B17/1219 , A61B17/12022 , A61B17/12113 , A61B17/12159 , A61B17/12172 , A61B17/12186 , A61B2017/1205 , A61B2017/12054 , A61B2017/12063 , A61B2017/12068
摘要： Delivery systems for liquid embolics and methods of using them are disclosed. The devices generally include a catheter and one or more retention elements to limit migration of the liquid embolic to non-target sites.
摘要翻译：公开了用于液体栓塞的输送系统及其使用方法。装置通常包括导管和一个或多个保留元件，以限制液体栓塞到非目标部位的迁移。

3. 发明申请

WO2015006999A1 泪小管阻芯审中-公开
公开(公告)号：WO2015006999A1
公开(公告)日：2015-01-22
申请号：PCT/CN2013/080552
申请日：2013-07-31
申请人：广州卫视博生物科技有限公司
发明人：高前应 , 李玉洁
IPC分类号： A61F9/007
CPC分类号： A61F9/00772 , A61B17/12036 , A61B17/12099 , A61B17/12159 , A61B2017/00849 , A61B2017/00893
摘要：一种泪小管阻芯，包括阻芯管体（1）,所述阻芯管体（1）一端具有锥形尖端（3），另一端具有阻芯头端（2）。所述泪小管阻芯不仅能够方便、安全地治疗干眼症，还能预防酸碱烧伤后的泪道变窄，所述阻芯头端（2）能够方便镊子取出或植入泪道。

4. 发明申请

WO2014128455A1 MEDICAL DEVICE FOR REDUCING BLEEDING 审中-公开
标题翻译：用于减少放血的医疗装置
公开(公告)号：WO2014128455A1
公开(公告)日：2014-08-28
申请号：PCT/GB2014/050479
申请日：2014-02-19
申请人： COOMARASAMY, Arri
发明人： COOMARASAMY, Arri , JAMESON, Richard
IPC分类号： A61B17/42 , A61B17/12 , A61B19/04 , A61M25/10 , A61B17/00 , A61M25/00
CPC分类号： A61B17/42 , A61B17/1204 , A61B17/12099 , A61B17/12136 , A61B17/12159 , A61B17/4241 , A61B42/00 , A61B50/30 , A61B2017/00557 , A61B2017/12004 , A61B2017/4216 , A61M27/00 , A61M2205/3344 , A61M2210/1433
摘要： A medical device (20) is disclosed for reducing bleeding comprising an outer flexible membrane (21) and an inner flexible membrane (22), an inflatable region (25), an inflow channel (23) and an interior region (29). The inflatable region (25) is defined between the between the inner and outer flexible membrane (22, 21). The inflow channel (23) is for inflation of the inflatable region (25) by communicating a fluid thereto. The interior region (29) is within the inflatable region (25), and is defined by the inner flexible membrane (22). The interior region (29) is configured to receive an insertion means (9,22) for positioning the medical device (20). The medical device (20) may be used to reduce post-partum haemorrhage (PPH). A method of using the medical device to reduce PPH is disclosed.
摘要翻译：公开了一种用于减少出血的医疗装置（20），其包括外柔性膜（21）和内柔性膜（22），可充气区域（25），流入通道（23）和内部区域（29）。可膨胀区域（25）被限定在内部和外部柔性膜（22,21）之间。流入通道（23）用于通过将流体连通到充气区域（25）来使其膨胀。内部区域（29）在可充气区域（25）内，并且由内部柔性膜（22）限定。内部区域（29）构造成容纳用于定位医疗装置（20）的插入装置（9,22）。医疗装置（20）可用于减少产后出血（PPH）。公开了一种使用该医疗装置来减少PPH的方法。

5. 发明申请

WO2013109398A1 SYSTEMS AND METHODS FOR TREATING FISTULAS IN THE LUNG AND TRACHEA 审中-公开
标题翻译：用于处理肺和血液中的模拟物的系统和方法
公开(公告)号：WO2013109398A1
公开(公告)日：2013-07-25
申请号：PCT/US2012/071832
申请日：2012-12-27
申请人： SPIRATION, INC.
发明人： SHEA, Richard, O. , SIROKMAN, William, A. , DILLARD, David, H. , GONZALES, Hugo, Xavier , SHUMAN, Brandon, James
IPC分类号： A61B17/08
CPC分类号： A61B17/0057 , A61B17/12104 , A61B17/12145 , A61B17/1215 , A61B17/12159 , A61B17/12172 , A61B17/12177 , A61B2017/00575 , A61B2017/00579 , A61B2017/00584 , A61B2017/00588 , A61B2017/00592 , A61B2017/00597 , A61B2017/00606 , A61B2017/00619 , A61B2017/00623
摘要： In certain embodiments, a device is configured to be compressed and inserted into the distal end of an endoscope. The delivery device can be configured to deliver the delivery catheter to the site of one or more fistulas in the wall of a body cavity or lumen within a patient. The delivery catheter is configured to deliver the device to the site of the one or more fistulas. The device is configured to expand at the site of the one or more fistulas and substantially seal the fistula in one or more directions. In some embodiments, at least a portion of the device is coated with and/or constructed of biocompatible material. In some configurations, the device is configured to be implanted for an extended period of time or even permanently. In some embodiments, at least a portion of the device is constructed of biodegradable, dissolvable and/or bioabsorbable material.
摘要翻译：在某些实施例中，设备被配置为被压缩并插入到内窥镜的远端中。递送装置可以被配置为将输送导管递送到患者体内或体腔的壁中的一个或多个瘘的部位。输送导管被配置为将装置递送到一个或多个瘘的部位。该装置构造成在一个或多个瘘的部位处膨胀并且在一个或多个方向上基本上密封瘘。在一些实施例中，装置的至少一部分用生物相容性材料涂覆和/或构造。在一些配置中，该设备被配置为长时间地甚至永久地植入。在一些实施方案中，装置的至少一部分由可生物降解，可溶解和/或生物吸收材料构成。

6. 发明申请

WO2013070838A1 OBSTRUCTION DEVICE 审中-公开
标题翻译：实施装置
公开(公告)号：WO2013070838A1
公开(公告)日：2013-05-16
申请号：PCT/US2012/064050
申请日：2012-11-08
申请人： EASYNOTES LTD. , KLEIN, David
发明人： KLEIN, David , FABIAN, Izhak , ALTMAN, Nir , HAAS, Steven , HIRSCH, Yoav
IPC分类号： A61B17/00
CPC分类号： A61B17/12159 , A61B17/12031 , A61B17/12036 , A61B17/12099 , A61B17/12172 , A61B2017/00592 , A61B2017/00615 , A61B2017/00818 , A61B2017/1205
摘要： An obstruction device (10) including an obstruction disc (12) mounted on a proximal portion of a shaft (14), the disc including an inner radial portion (16) and an outer radial portion (18), wherein the outer radial portion is more bendable than the inner radial portion.
摘要翻译：一种阻塞装置（10），包括安装在轴（14）的近端部分上的阻塞盘（12），所述盘包括内部径向部分（16）和外径向部分（18），其中所述外部径向部分比内径向部分更弯曲。

7. 发明申请

WO2013016098A2 PERSONALIZABLE SYSTEM AND METHOD FOR ANESTHETIZING THE TYMPANIC MEMBRANE 审中-公开
标题翻译：个性化系统及其方法
公开(公告)号：WO2013016098A2
公开(公告)日：2013-01-31
申请号：PCT/US2012/047179
申请日：2012-07-18
申请人： ACCLARENT, INC. , ANDREAS, Bernard H. , SALEKI, Mansour , GIROTRA, Rohit , CANTU, Alfredo , BHAT, Nikhil
发明人： ANDREAS, Bernard H. , SALEKI, Mansour , GIROTRA, Rohit , CANTU, Alfredo , BHAT, Nikhil
IPC分类号： A61F11/00 , A61F11/12
CPC分类号： A61M11/006 , A61B17/12159 , A61F11/00 , A61F11/004 , A61F11/12 , A61F2011/085 , A61M19/00 , A61M31/00 , A61M2210/0662
摘要： Systems and methods are provided for anesthetizing a tympanic membrane of an ear. The systems are personalizable to ensure proper anesthetizing solution administration. The systems and methods may also be useful for administering a solution to the ear canal of a human patient and for maintaining the solution therein.
摘要翻译：提供用于麻醉耳朵鼓膜的系统和方法。这些系统是可个性化的，以确保适当的麻醉溶液给药。所述系统和方法还可用于将人体患者的耳道的溶液施用并将其溶解于其中。

8. 发明申请

WO2010093873A3 DRUG DELIVERY THROUGH HYDROGEL PLUGS 审中-公开
标题翻译：药物通过HYDROGEL PLUG递送
公开(公告)号：WO2010093873A3
公开(公告)日：2011-04-14
申请号：PCT/US2010024029
申请日：2010-02-12
申请人： INCEPT LLC , SAWHNEY AMARPREET S , JARRETT PETER , BASSETT MICHAEL , BLIZZARD CHARLES D
发明人： SAWHNEY AMARPREET S , JARRETT PETER , BASSETT MICHAEL , BLIZZARD CHARLES D
IPC分类号： A61M31/00 , A61F2/02 , A61F9/007 , A61K9/06 , A61K31/437 , A61K47/30 , A61M5/00 , A61P27/02
CPC分类号： A61K9/0051 , A61B17/12099 , A61B17/12159 , A61B17/1219 , A61F9/00772 , A61F2250/0067 , A61K31/135 , A61K31/437
摘要： An embodiment is a medical prosthesis for blocking or reducing tear flow through a punctum or canaliculus of a human eye and delivering a drug to the eye that comprises a dehydrated covalently crosslinked synthetic hydrophilic polymer hydrogel with dimensions to pass through a puncta lacrimali, with the dehydrated hydrogel absorbing physiological water to swell to at least 1 mm in cross-sectional width and conformably fit a canaliculus, with the hydrogel comprising a therapeutic agent dispersed through the hydrogel for release to an eye, with the hydrogel having a water content of at least about 50% by weight or volume when allowed to fully hydrate in vitro in physiological saline.
摘要翻译：一个实施方案是用于阻断或减少穿过人眼的泪点或泪管的泪液的药物假体，并将药物递送至眼睛，该药物包括脱水的共价交联的合成亲水性聚合物水凝胶，其尺寸通过泪点，脱水水凝胶吸收生理水以横截面宽度膨胀至至少1mm，并且顺应地配合小孔，其中水凝胶包含分散在水凝胶中的治疗剂以释放至眼睛，水凝胶的水含量至少约为当在生理盐水中体外充分水合时，其重量为50％或体积。

9. 发明申请

WO2010030485A1 DEVICE FOR OCCLUDING VASCULAR DEFECTS 审中-公开
标题翻译：用于监测血管缺损的装置
公开(公告)号：WO2010030485A1
公开(公告)日：2010-03-18
申请号：PCT/US2009/054476
申请日：2009-08-20
申请人： AGA MEDICAL CORPORATION , AMPLATZ, Kurt , HEIDNER, Matthew, C. , REN, Brooke , RUSSO, Patrick , ADAMS, Daniel, O.
发明人： AMPLATZ, Kurt , HEIDNER, Matthew, C. , REN, Brooke , RUSSO, Patrick , ADAMS, Daniel, O.
IPC分类号： A61M29/00
CPC分类号： A61B17/0057 , A61B17/12022 , A61B17/12045 , A61B17/12109 , A61B17/12113 , A61B17/12122 , A61B17/12159 , A61B17/12163 , A61B17/12172 , A61B17/12177 , A61B90/39 , A61B2017/00575 , A61B2017/00601 , A61B2017/00606 , A61B2017/00831
摘要： A multi-layer occluder for treating a target site within the body is provided. The occluder may include first and second layers. For example, the first layer may include braided strands of metallic material, and the second layer may include braided strands of polymeric material. At least one of the first or second layers may be configured to facilitate thrombosis.
摘要翻译：提供了用于治疗身体内的靶部位的多层封堵器。封堵器可以包括第一和第二层。例如，第一层可以包括金属材料的编织线，并且第二层可以包括聚合材料的编织线。第一或第二层中的至少一个可以被配置为便于血栓形成。

10. 发明申请

WO2010026240A1 TEMPORARY EMBOLIC PROTECTION DEVICE AND MEDICAL PROCEDURE FOR DELIVERY THEREOF 审中-公开
标题翻译：临时手术保护装置及其输送医疗手续
公开(公告)号：WO2010026240A1
公开(公告)日：2010-03-11
申请号：PCT/EP2009/061509
申请日：2009-09-04
申请人： Karolinska Institutet Innovations AB , JÖNSSON, Anders
发明人： JÖNSSON, Anders
IPC分类号： A61F2/01
CPC分类号： A61B17/12109 , A61B17/12036 , A61B17/1204 , A61B17/12159 , A61B17/12172 , A61B2017/1205 , A61F2/01 , A61F2002/018 , A61F2230/0008 , A61F2230/0069 , A61F2230/0076 , A61F2230/0093
摘要： An embolic protection device (200) and medical procedure for positioning the device in the aortic arch (100) is disclosed. The device and method effectively prevent material (150) from entering with blood flow into side branch vessels (116, 118, 120) of the aortic arch. The device is a collapsible embolic protection device devised for temporary transvascular delivery to an aortic arch of a patient, wherein the device has a protection unit that comprises a selectively permeable unit adapted to prevent embolic material from passage with a blood flow into a plurality of aortic side branch vessels at the aortic arch. The protection unit is permanently attached to a transvascular delivery unit (130) at a connection point provided at the selectively permeable unit, and a first support member for the protection unit that is at least partly arranged at a periphery of the selectively permeable unit. In an expanded state of the device, the connection point is enclosed by the first support member or arranged at said support member.
摘要翻译：公开了用于将装置定位在主动脉弓（100）中的栓塞保护装置（200）和医疗程序。该装置和方法有效地防止物质（150）进入血流进入主动脉弓的侧分支血管（116,118,120）。该装置是一种可折叠的栓塞保护装置，其设计用于临时经血管递送至患者的主动脉弓，其中该装置具有保护单元，该保护单元包括选择性渗透单元，该单元适于防止栓塞材料通过血液流入多个主动脉主动脉弓侧支血管。保护单元在设置在选择性渗透单元处的连接点处永久地附接到经血管输送单元（130），以及用于保护单元的第一支撑构件，其至少部分地布置在选择性渗透单元的周边。在装置的展开状态下，连接点由第一支撑构件包围或设置在所述支撑构件上。

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