专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2006019533A3 IMAGE PROCESSING AND ANALYSIS OF ARRAY DATA 审中-公开
标题翻译：图像处理和阵列数据分析
公开(公告)号：WO2006019533A3
公开(公告)日：2006-04-06
申请号：PCT/US2005023193
申请日：2005-06-28
申请人： BIOARRAY SOLUTIONS LTD , XIONGWU XIA , YIPING GUAN
发明人： XIONGWU XIA , YIPING GUAN
IPC分类号： G06K9/00
CPC分类号： G06K9/3275 , G06K2209/07 , G06T7/73 , G06T2207/30072
摘要： Disclosed are methods of processing images, and in particular aligning and orienting grids from a fluorescent array of signal sources, by linking nearest neighbor sources to form a hexagon, and then using the hexagon lines for alignment and orientation of the grid. Also disclosed are methods and algorithms for aligning image with grid and correcting for signal beads which are smaller than a grid field and the shift in a grid field. These methods can be used where the signal sources are fluorescent images from a microarray. Also disclosed are methods of automated watershed clustering following transformation.
摘要翻译：公开了处理图像的方法，特别是通过链接最近邻源来形成六边形，并且然后使用六边形线来对准和定向网格，从信号源的荧光阵列对齐和定向网格的方法。还公开了用于将图像与网格对齐并校正小于网格场的信号珠和网格场中的偏移的方法和算法。这些方法可用于信号源是来自微阵列的荧光图像。还公开了转化后的自动分水岭聚类的方法。

2. 发明申请

WO2004047007A1 ANALYSIS, SECURE ACCESS TO, AND TRANSMISSION OF ARRAY IMAGES 审中-公开
标题翻译：分析，安全访问和传输阵列图像
公开(公告)号：WO2004047007A1
公开(公告)日：2004-06-03
申请号：PCT/US2003/036560
申请日：2003-11-14
申请人： BIOARRAY SOLUTIONS, LTD. , SEUL, Michael , XIA, Xiongwu , CHAU, Chiu
发明人： SEUL, Michael , XIA, Xiongwu , CHAU, Chiu
IPC分类号： G06K9/00
CPC分类号： G06T7/0012 , G01N33/566 , G06K9/00 , G06K9/00147 , G06K2209/07 , G06T7/11 , G06T7/155 , G06T7/33 , G06T2207/10064 , G06T2207/20152 , G06T2207/30072
摘要： Systems and methods are provided the autocentering, autofocusing, acquiring, decoding, aligning, analyzing and exchanging among various parties, images, where the images are of arrays of signals associated with ligand-receptor interactions, and more particularly, ligand-receptor interactions where a multitude of receptors are associated with microparticles or microbeads. The beads are encoded to indicate the identity of the receptor attached, and therefore, an assay image and a decoding image are aligned to effect the decoding. The images or data extracted from such images can be exchanged between de-centralized assay locations and a centralized location where the data are analyzed to indicate assay results. Access to data can be restricted to authorized parties in possession of certain coding information, so as to preserve confidentiality.
摘要翻译：系统和方法提供了各方之间的自动对焦，自动聚焦，获取，解码，对准，分析和交换，其中图像是与配体 - 受体相互作用相关联的信号阵列，更具体地，配体 - 受体相互作用，其中许多受体与微粒或微珠相关。编码珠以指示所连接的受体的身份，因此，分析图像和解码图像被对准以实现解码。从这些图像提取的图像或数据可以在非集中测定位置和分析数据的集中位置之间交换以指示测定结果。访问数据可以限于拥有某些编码信息的授权方，以保护机密性。

3. 发明申请

WO2011137183A1 METHOD AND SYSTEM FOR ACCURATE ALIGNMENT AND REGISTRATION OF ARRAY FOR DNA SEQUENCING 审中-公开
标题翻译：用于DNA序列的精确对准和阵列注册的方法和系统
公开(公告)号：WO2011137183A1
公开(公告)日：2011-11-03
申请号：PCT/US2011/034178
申请日：2011-04-27
申请人： COMPLETE GENOMICS, INC. , STAKER, Bryan P.
发明人： STAKER, Bryan P.
IPC分类号： C40B20/02 , C40B40/06
CPC分类号： C12Q1/6874 , G06K9/32 , G06K9/42 , G06K2209/07 , G06T7/0012 , G06T7/32 , G06T7/337 , G06T7/74 , G06T2207/10056 , G06T2207/30072
摘要： In a genome sequencing system and methodology, a protocol is provided to precisely and accurately align and register an image of a planar array of nanoballs for optical analysis. Minimization techniques and Moire averaging are used to correct or errors In subperiod x-y offset, scale, and rotation. In Moire averaging, magnification is set so that the pixel period of the imaging element is a noninteger multiple of the site period. Accurate registration is achieved by providing for pre-defined pseudo-random sets of sites, where nanoballs are prevented from attachment to the substrate so that the sites of the array can be used in a pattern matching scheme as registration markers for absolute location identification. Information can be extracted with a high degree of confidence that it is correlated to a known location, while at the same time the amount of information that can be packed on a chip is maximized.
摘要翻译：在基因组测序系统和方法学中，提供了一种协议，用于精确和准确地对准和注册用于光学分析的纳米壁的平面阵列的图像。最小化技术和莫尔平均用于校正或误差在次周期x-y偏移，刻度和旋转。在莫尔平均中，设置放大倍率，使得成像元件的像素周期是站点周期的非整数倍。通过提供预定义的伪随机集合的位置来实现准确的注册，其中防止了纳米线附着到基底，使得阵列的位置可以以模式匹配方案用作绝对位置识别的登记标记。可以高信度地提取信息，使其与已知位置相关联，同时可将芯片上打包的信息量最大化。

4. 发明申请

WO01069534A2 METHODS AND APPARATUS FOR IMAGE ANALYSIS 审中-公开
标题翻译：图像分析方法与装置
公开(公告)号：WO01069534A2
公开(公告)日：2001-09-20
申请号：PCT/US2001/007711
申请日：2001-03-09
IPC分类号： G06K9/36 , G06K9/46 , G06K9/66 , G06T5/00 , G06T7/00
CPC分类号： G06K9/00 , G06K2209/07 , G06T7/0012 , G06T7/11 , G06T7/73 , G06T2207/10064 , G06T2207/30072
摘要： Image analysis techniques may be provided. Location of objects in an image may be determined based on intensity characteristics of pixels in the image. Objects that have been located may be mapped to a source for the objects based for example, on a grid structure that may have been used to place the objects. Differential analysis of objects of two source materials in images may be determined based on aligned versions of the images. Filtering may be used to weigh pixel characteristics. Such object analysis techniques may have been encoded into a set of machine-executable instructions and stored on a machine-readable storage medium for use by equipment that is to perform the techniques.
摘要翻译：可以提供图像分析技术。可以基于图像中的像素的强度特性来确定图像中的对象的位置。已经定位的对象可以被映射到例如基于可能已经用于放置对象的网格结构的对象的源。可以基于图像的对准版本来确定图像中的两个源材料的对象的差分分析。滤波可用于权重像素特性。这样的对象分析技术可能已被编码成一组机器可执行指令，并且存储在机器可读存储介质上，供由要执行技术的设备使用。

5. 发明申请

WO2013040448A1 SIMULTANEOUS ACQUISITION OF BIOMETRIC DATA AND NUCLEIC ACID 审中-公开
标题翻译：同时获取生物量数据和核酸
公开(公告)号：WO2013040448A1
公开(公告)日：2013-03-21
申请号：PCT/US2012/055560
申请日：2012-09-14
申请人： LIFE TECHNOLOGIES CORPORATION , HARROLD, Michael , HENNESSY, Lori , LAGACE, Robert
发明人： HARROLD, Michael , HENNESSY, Lori , LAGACE, Robert
IPC分类号： G06K9/00 , A61B5/15 , A61B5/151 , A61B5/157 , A61B5/145
CPC分类号： G06K9/00013 , A61B5/1172 , A61B5/1174 , A61B5/1176 , A61B5/14546 , A61B5/150022 , A61B5/150099 , A61B5/150229 , A61B5/150267 , A61B5/150305 , A61B5/150396 , A61B5/150404 , A61B5/150419 , A61B5/150427 , A61B5/150435 , A61B5/150511 , A61B5/150748 , A61B5/150755 , A61B5/150786 , A61B5/150847 , A61B5/150954 , A61B5/15109 , A61B5/1519 , A61B5/157 , A61B10/0045 , A61B10/02 , G05B1/00 , G06K9/00006 , G06K9/0008 , G06K9/00107 , G06K9/00892 , G06K2209/07
摘要： Disclosed are devices and methods for collection and analyzing biological samples containing nucleic acid in conjunction with collecting at least one ridge and valley signature of a test subject, while keeping the sample and signature associated with each other. Such devices and methods are used in forensic, human identification, screening, and access control technologies to rapidly process an individual's identity or determine the identity of an individual.
摘要翻译：公开了用于收集和分析含有核酸的生物样品的装置和方法，并结合收集测试对象的至少一个脊和谷签名，同时保持样品和签名彼此相关联。这些设备和方法用于法医，人类识别，筛查和访问控制技术，以快速处理个人的身份或确定个人的身份。

6. 发明申请

WO2010047055A1 車両の周辺監視装置审中-公开
标题翻译：用于监测车辆周边区域的装置
公开(公告)号：WO2010047055A1
公开(公告)日：2010-04-29
申请号：PCT/JP2009/005261
申请日：2009-10-08
申请人：本田技研工業株式会社 , 松田幸大 , 長岡伸治 , 高津戸泉
发明人：松田幸大 , 長岡伸治 , 高津戸泉
IPC分类号： G08G1/16 , B60R1/00 , B60R11/02 , G06T1/00 , H04N7/18
CPC分类号： B60R1/00 , B60R2300/105 , B60R2300/205 , B60R2300/301 , B60R2300/307 , B60R2300/70 , B60R2300/8033 , G06K9/00369 , G06K9/00805 , G06K2209/07 , G06T7/11 , G06T7/136 , G06T2207/10048 , G06T2207/20132 , G06T2207/30196 , G06T2207/30261
摘要：　車両周辺の対象物をより良好な精度で背景と分離して抽出する。車両の周辺を監視する装置は、車両の外気温を検出し、該外気温に基づいて推定された対象物の表面温度と該外気温との温度差を求める。赤外線カメラによって得られた撮像画像における背景の輝度値および該温度差に対応する輝度差に基づいて、対象物の輝度値を算出する。該対象物の輝度値を閾値として撮像画像を２値化し、対象物を抽出する。外気温と対象物の表面温度との関係に基づいて２値化の閾値を設定するので、より良好な精度で背景と分離して対象物を抽出することができる。　
摘要翻译：提供了用于监视车辆的周围区域的装置。该设备从背景中更精确地分离并提取车辆周围的物体。该装置检测车辆的环境温度，并且确定环境温度和基于环境温度估计的物体表面温度之间的温度差。基于由红外线摄像机获得的拍摄图像的背景的亮度值和对应于温度差的亮度差，计算对象的亮度值。通过使用对象的亮度值作为阈值对拍摄图像进行二值化处理，并提取对象。由于根据环境温度和物体表面温度之间的关系来设定二值阈值，所以可以从背景中以更好的精度分离和提取物体。

7. 发明申请

WO2010017206A1 IMAGE ANALYSIS 审中-公开
标题翻译：图像分析
公开(公告)号：WO2010017206A1
公开(公告)日：2010-02-11
申请号：PCT/US2009/052718
申请日：2009-08-04
申请人： HELICOS BIOSCIENCES CORPORATION , EMHOFF, John , HEALY, John , MOULTON, Keith
发明人： EMHOFF, John , HEALY, John , MOULTON, Keith
IPC分类号： G06K9/00
CPC分类号： G06K9/00 , G06K2209/07
摘要： Image processing for certain sequencing technologies requires data processing algorithms that provide fast sequence detection with low error rates. Methods and apparatus for performing image analysis for identifying nucleotide incorporations includes performing an image segmentation procedure on a plurality of data sets to identify sample objects and to create segmented data sets for each of the data sets. Each data set represents a sample image that includes a plurality of pixel locations and intensity data associated with each of the pixel locations. The segmented data sets represent identified sample objects for each one of the sample image data sets. An image registration procedure is performed on the segmented data sets to align the identified sample objects and to create data representative of the aligned identified sample objects. A strand formation procedure is then performed on the data representative of the aligned identified sample objects to identify nucleotide incorporations.
摘要翻译：某些测序技术的图像处理需要数据处理算法，可以提供具有低错误率的快速序列检测。用于进行用于识别核苷酸掺入的图像分析的方法和装置包括对多个数据集执行图像分割过程以识别样本对象，并为每个数据集创建分段数据集。每个数据集表示包括与每个像素位置相关联的多个像素位置和强度数据的样本图像。分段数据集表示每个样本图像数据集的标识样本对象。对分割的数据集执行图像注册过程以对准所识别的样本对象并创建表示对准的识别的样本对象的数据。然后对表示对准的鉴定的样本对象的数据进行链形成程序以鉴定核苷酸掺入。

8. 发明申请

WO2009032509A1 NUCLEIC ACID SEQUENCING BY SELECTIVE EXCITATION OF MICROPARTICLES 审中-公开
标题翻译：通过选择性激活微阵列进行核酸序列测序
公开(公告)号：WO2009032509A1
公开(公告)日：2009-03-12
申请号：PCT/US2008/073349
申请日：2008-08-15
申请人： LIGHTSPEED GENOMICS, INC. , HONG, Stanley, S. , RYU, Jekwan , PARK, Jong, Buhm
发明人： HONG, Stanley, S. , RYU, Jekwan , PARK, Jong, Buhm
IPC分类号： C12Q1/68 , G01N21/45
CPC分类号： G06K9/00 , C12Q1/6869 , G01N21/6428 , G06K2209/07 , Y10T436/143333 , C12Q2563/107 , C12Q2563/149
摘要： Nucleic acid microparticles are sequenced by performing a sequencing reaction on the microparticles using one or more reagents, selectively exciting the microparticles in an excitation pattern, optically imaging the microparticles at a resolution insufficient to resolve individual microparticles, and processing the optical images of the microparticles using information on the excitation pattern to determine the presence or absence of the optical signature, which indicates the sequence information of the nucleic acid. An apparatus for optical excitation of the microparticles comprises an optical fiber delivering a first laser beam, and an interference pattern generation module coupled to the optical fiber. The interference pattern generation module splits the first laser beam into second and third laser beams and generates the excitation pattern for selectively exciting the microparticles by interference between the second and third laser beams.
摘要翻译：通过使用一种或多种试剂对微粒进行测序反应来对核酸微粒进行测序，选择性地以激发图案激发微粒，以不足以分辨各个微粒的分辨率光学成像微粒，并使用以下方式处理微粒的光学图像关于激发模式的信息以确定光学特征的存在或不存在，其指示核酸的序列信息。用于微粒的光激发的装置包括传送第一激光束的光纤和耦合到光纤的干涉图案生成模块。干涉图案生成模块将第一激光束分割成第二和第三激光束，并产生用于通过第二和第三激光束之间的干涉选择性地激发微粒的激励图案。

9. 发明申请

WO2017032595A1 TISSUE MICROARRAY ANALYSIS 审中-公开
标题翻译：组织微量分析
公开(公告)号：WO2017032595A1
公开(公告)日：2017-03-02
申请号：PCT/EP2016/068995
申请日：2016-08-10
申请人： KONINKLIJKE PHILIPS N.V.
发明人： WIMBERGER-FRIEDL, Reinhold , PIERIK, Anke
IPC分类号： G06K9/00 , G06T7/00 , G06T11/00
CPC分类号： G06K9/0014 , G06K9/00671 , G06K2209/07 , G06T7/337 , G06T2207/10056 , G06T2207/30024 , G06T2207/30072
摘要： The present invention relates to digital pathology. In order to facilitate analyzing a tissue microarray, an apparatus is provided for tissue examination. The apparatus comprises a data input (102), a tissue microarray analyzing unit (104), and an output (106). The data input is configured to receive a reference image of a reference slice obtained from a tissue sample block; and to receive a microarray image of a microarray slice comprising at least one tissue core obtained from at least the tissue sample block. The tissue microarray analyzing unit is configured to register tissue core images of at least one tissue core with the reference image based on a spatial arrangement of the respective tissue core within the tissue sample block. The output is configured to provide a registered result obtained from the tissue microarray analyzing unit for further analyzing purposes.
摘要翻译：本发明涉及数字病理学。为了便于分析组织微阵列，提供了用于组织检查的装置。该装置包括数据输入（102），组织微阵列分析单元（104）和输出（106）。数据输入被配置为接收从组织样本块获得的参考切片的参考图像; 以及接收微阵列切片的微阵列图像，其包含从至少所述组织样本块获得的至少一个组织芯。组织微阵列分析单元被配置为基于组织样本块内的相应组织核心的空间排列，将具有参考图像的至少一个组织核心的组织核心图像记录。输出被配置为提供从组织微阵列分析单元获得的注册结果，以进一步分析目的。

10. 发明申请

WO2012090198A3 AN APPARATUS AND METHOD FOR AUTOMATIC DETECTION OF PATHOGENS 审中-公开
标题翻译：自动检测病原体的装置和方法
公开(公告)号：WO2012090198A3
公开(公告)日：2012-11-15
申请号：PCT/IL2011000973
申请日：2011-12-29
申请人： PARASIGHT LTD , BACHELET IDO , POLLAK JOSEPH JOEL , LEVNER DANIEL , BILU YONATAN , YORAV-RAPHAEL NOAM
发明人： BACHELET IDO , POLLAK JOSEPH JOEL , LEVNER DANIEL , BILU YONATAN , YORAV-RAPHAEL NOAM
IPC分类号： G06K9/00
CPC分类号： B01L3/502715 , B01L2300/0816 , B01L2300/0864 , G01N15/1463 , G01N21/23 , G01N21/5907 , G01N21/6458 , G01N2015/008 , G01N2015/1006 , G01N2015/1465 , G01N2021/5957 , G01N2021/6419 , G01N2021/6421 , G06K2209/05 , G06K2209/07
摘要： The invention discloses an apparatus and method for automatic detection of pathogens within a sample. The apparatus and method are especially useful for high-throughput and/or low-cost detection of parasites with minimal need for trained personnel. The invention entails automated microscopic data acquisition, and performing image processing of images captured from a sample using classification algorithms. Visual classification features of structures are extracted from the image and compared to visual classification features associated with known pathogens. A determination is reached whether a pathogen is present in the sample; and if present, the pathogen may be identified to a pathogen species. Diagnosis is rapid and does not require medically trained personnel.
摘要翻译：本发明公开了用于自动检测样品内的病原体的设备和方法。该装置和方法特别适用于高通量和/或低成本的寄生虫检测，而对训练有素的人员的需求最小。本发明需要自动化的显微数据采集，并使用分类算法对从样本中捕获的图像执行图像处理。从图像中提取结构的视觉分类特征，并将其与已知病原体相关的视觉分类特征进行比较。确定样品中是否存在病原体; 并且如果存在的话，病原体可以被鉴定为病原体物种。诊断速度快，不需要经过医疗培训的人员。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式