专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2016018939A2 METHODS FOR SEPARATING MIXTURES 审中-公开
标题翻译：分离混合物的方法
公开(公告)号：WO2016018939A2
公开(公告)日：2016-02-04
申请号：PCT/US2015/042526
申请日：2015-07-28
申请人： UNIVERSITY OF IOWA RESEARCH FOUNDATION
发明人： SCHULTZ, Michael, K. , KNIGHT, Andrew, W. , EITRHEIM, Eric, S. , ZALUPSKI, Peter, R.
IPC分类号： C01F17/00 , B01D15/08
CPC分类号： B01D59/26 , B01D15/08 , B01J20/20 , B01J20/28083 , B01J20/282 , B01J2220/52 , C01F17/0006 , C01G15/003 , C01G99/003 , C22B58/00 , G21F9/007 , G21F9/12 , G21Y2002/10 , G21Y2002/60 , G21Y2004/20
摘要： Methods to separate protactinium and gallium and isotopes thereof from mixtures are provided.
摘要翻译：提供了从混合物中分离prot ium和镓及其同位素的方法。

2. 发明申请

WO2013134251A3 ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE 审中-公开
标题翻译：阴离子交换 - 疏水混合模式
公开(公告)号：WO2013134251A3
公开(公告)日：2015-07-02
申请号：PCT/US2013029097
申请日：2013-03-05
申请人： BIO RAD LABORATORIES
发明人： LIAO JIALI , FROST RUSSELL
IPC分类号： B01D15/08 , B01J20/26
CPC分类号： B01J41/20 , B01D15/265 , B01D15/30 , B01D15/327 , B01D15/363 , B01D15/3847 , B01J20/22 , B01J20/267 , B01J20/28016 , B01J20/281 , B01J20/286 , B01J20/288 , B01J20/289 , B01J20/3208 , B01J20/3217 , B01J20/3219 , B01J20/3253 , B01J20/3265 , B01J20/3293 , B01J41/04 , B01J41/09 , B01J2220/52 , C07K1/14 , C07K1/16 , C07K1/165 , C07K16/00 , G01N30/482
摘要： Anion exchange-hydrophobic mixed mode ligands and methods of their use are provided.
摘要翻译：提供阴离子交换疏水混合模式配体及其使用方法。

3. 发明申请

WO2009099375A1 METHOD FOR PRODUCTION OF SEPARATION MEDIA 审中-公开
标题翻译：分离介质的生产方法
公开(公告)号：WO2009099375A1
公开(公告)日：2009-08-13
申请号：PCT/SE2009/000063
申请日：2009-01-30
申请人： GE HEALTHCARE BIO-SCIENCES AB , GLAD, Gunnar , JOHANSSON, Bo-Lennart , MALOISEL, Jean-Luc , NORRMAN, Nils , STENHOLM, Åke
发明人： GLAD, Gunnar , JOHANSSON, Bo-Lennart , MALOISEL, Jean-Luc , NORRMAN, Nils , STENHOLM, Åke
IPC分类号： B01J20/285 , B01J2/14
CPC分类号： B01J20/291 , B01J20/262 , B01J20/2809 , B01J20/285 , B01J20/286 , B01J20/287 , B01J20/288 , B01J20/3212 , B01J20/3268 , B01J20/3274 , B01J20/3293 , B01J39/26 , B01J41/20 , B01J2220/52
摘要： The present invention relates to a method for production of separation media using a so called Spinning Disc technology wherein the porosities of the beads are optimized in such a way that a desired biomolecule may be separated from a complex sample. The method comprises the following steps: a) feeding a 4-8% polysaccharide solution, which has a viscosity within 350-450 mPas, at 65-75°C to one or more spinning discs at 3001-3010 rpm to form polysaccharide beads; b) capturing said formed polysaccharide beads in a capturing bath; wherein the porosity of the polysaccharide beads is controlled by varying the temperature of the capturing between 15 and 27°C, preferably between 17.5 and 24.6°C. The method yields porosities that prevent molecules larger than 150 000 g/mol to diffuse into the beads. The invention also relates to separation media produced by the method and use thereof for purification of biomolecules, in particular monoclonal antibodies.
摘要翻译：本发明涉及使用所谓的旋转圆盘技术生产分离介质的方法，其中珠子的孔隙度以使得所需生物分子可以与复杂样品分离的方式进行优化。该方法包括以下步骤：a）将具有350-450mPa·s粘度的4-8％多糖溶液在65-75℃下以3001-3010rpm向一个或多个纺丝盘送入以形成多糖珠; b）在捕获浴中捕获所述形成的多糖珠粒; 其中多糖珠的孔隙率通过在15和27℃之间，优选在17.5和24.6℃之间改变捕获温度来控制。该方法产生阻止大于150000g / mol的分子扩散到珠中的孔隙率。本发明还涉及通过其用于纯化生物分子，特别是单克隆抗体的方法和用途产生的分离培养基。

4. 发明申请

WO2006081002A2 CHROMATOGRAPHIC MEDIA 审中-公开
标题翻译：色谱介质
公开(公告)号：WO2006081002A2
公开(公告)日：2006-08-03
申请号：PCT/US2005/045710
申请日：2005-12-16
申请人： MALLINCKRODT BAKER, INC. , DEORKAR, Nandu , BUSS, Robert, C. , MLADOSICH, Joseph, M. , BOUIS, Paul, A.
发明人： DEORKAR, Nandu , BUSS, Robert, C. , MLADOSICH, Joseph, M. , BOUIS, Paul, A.
CPC分类号： B01J41/14 , B01D15/327 , B01D15/363 , B01D15/364 , B01J20/261 , B01J20/262 , B01J20/265 , B01J20/28004 , B01J20/285 , B01J20/288 , B01J20/3092 , B01J20/321 , B01J20/3255 , B01J20/3272 , B01J20/328 , B01J20/3285 , B01J2220/52 , B01J2220/54 , B01J2220/58 , C07K1/165
摘要： This invention concerns the preparation and use of novel polymeric chromatographic media and preferably mixed mode polymeric chromatographic media. In accordance with the present invention, polymeric media is prepared using polymeric particles derivatized with polyethyleneimine, and preferably such polyethyleneimine derivatized polymeric particles further functionalized with appropriate reactants. The polymeric chromatographic media is especially useful for bioseparations.
摘要翻译：本发明涉及新型聚合物色谱介质和优选混合模式聚合物色谱介质的制备和使用。根据本发明，使用用聚乙烯亚胺衍生的聚合物颗粒制备聚合物介质，并且优选用适当的反应物进一步官能化的这种聚乙烯亚胺衍生的聚合物颗粒。高分子色谱介质特别适用于生物分离。

5. 发明申请

WO2005106454A1 被検抗原内の生菌を特異的に標識化して検出する検出方法及び検出装置审中-公开
标题翻译：用于通过特异性标签检测受试者抗原中活体细胞的方法和装置
公开(公告)号：WO2005106454A1
公开(公告)日：2005-11-10
申请号：PCT/JP2005/003584
申请日：2005-03-03
申请人：御子柴徹 , 佐々木哲朗 , 円城寺隆治
发明人：御子柴徹 , 佐々木哲朗 , 円城寺隆治
IPC分类号： G01N30/48
CPC分类号： G01N33/56911 , B01J20/286 , B01J20/3242 , B01J2220/52 , B01J2220/54 , B01J2220/58 , G01N21/6428 , G01N21/78 , G01N33/58
摘要：　被抗原内の生菌を特異的に標識化することによって、抗原としての微生物のうちの生菌を短時間で迅速に検出することができ、加えて検査の確実性をも担保し得る検出方法及び検出装置を提供する。大腸菌などの被検抗原に、その被検抗原内の生菌（標的菌１２）によって酵素分解される標識化物質１３を作用させた標識化抗原１４を生成した後、被検抗原に特異的に結合し得る特異的結合抗体を固定化してなる固定相において、その標識化抗原１４を捕捉することを特徴とする。
摘要翻译：一种用于检测的方法和装置，其中通过特异性标记测试受试者抗原内的活细菌，可以在短时间内快速检测作为抗原的微生物中的活细菌，并且由此可以确保测试保证。该方法和装置的特征在于，通过动作，在测试对象抗原例如大肠杆菌上，通过活体细菌（靶细菌（12））酶活化的标记物质（13）在受试对象抗原内形成标记的抗原（14），并将所得标记的抗原（14）捕获在其上固定有能够特异性结合测试受试者抗原的特异性结合抗体的固定相上。

6. 发明申请

WO02096553A3 INORGANIC ABSORBENT COMPOSITES CONTAINING CUCURBITURILS, METHOD FOR THE PRODUCTION THEREOF AND USE OF THE SAME 审中-公开
标题翻译：无机，葫芦含有吸收性复合材料，方法制备方法和用途
公开(公告)号：WO02096553A3
公开(公告)日：2003-03-13
申请号：PCT/DE0201980
申请日：2002-05-27
申请人： SYNTEC GES FUER CHEMIE UND TEC , RICHTER ANDREAS M , FELICETTI MICHAEL
发明人： RICHTER ANDREAS M , FELICETTI MICHAEL
IPC分类号： B01J20/26 , B01J20/30 , B01J20/32 , B01J20/10
CPC分类号： G01N30/482 , B01J20/08 , B01J20/103 , B01J20/26 , B01J20/262 , B01J20/285 , B01J20/30 , B01J20/3204 , B01J20/3272 , B01J2220/46 , B01J2220/52 , B01J2220/54
摘要： The invention relates to novel inorganic absorbent composites consisting of an open-pore, solid, inorganic matrix, comprising cucurbiturils of general formula (I) which are chemically linked in the matrix. Said cucurbiturils form a macrocycle having a cage structure, consisting of n repeating units, wherein n is a whole number 5, 6, 7 or 8, R represents hydrogen or C1-C5 alkyl, and X represents O, S or N. X and R can be the same or different. Said composites are produced by reacting cucurbituril with an inorganic matrix-forming agent, such as silica gel, at 15 to 90°C in a liquid medium. The inventive composites can be used as absorption materials and catalyst supports.
摘要翻译：本发明涉及一种开孔的新颖无机吸收性复合材料，在化学结合基体固体无机基质葫芦脲通式（I），其中，所述葫芦脲形成笼形结构大环组成的重复单元n，其中n为整数5的，6，7或8，并且其中R具有的含义为氢或C1-C5烷基，且X为O，S或N，并且其中X和R可以是相同的或不同的。制备通过葫芦脲的反应与无机基质中的液体介质中进行，如硅胶，在15至90℃。用的是尽可能的吸收材料和Katalysatortrâger。

7. 发明申请

WO2002066135A1 A MICROCHIP ELECTROSPRAY DEVICE AND COLUMN WITH AFFINITY ADSORBENTS AND USE OF THE SAME 审中-公开
标题翻译： MICROCHIP ELECTROSPRAY设备和带有亲和吸附剂的柱及其使用
公开(公告)号：WO2002066135A1
公开(公告)日：2002-08-29
申请号：PCT/US2002/004700
申请日：2002-02-19
申请人： ADVION BIOSCIENCES, INC.
发明人： ZHANG, Sheng , HUANG, Xian
IPC分类号： B01D15/08
CPC分类号： G01N30/6095 , B01D15/3804 , B01J20/28042 , B01J20/285 , B01J20/286 , B01J20/321 , B01J20/3212 , B01J20/3219 , B01J20/3244 , B01J20/3251 , B01J20/3274 , B01J45/00 , B01J2220/52 , B01J2220/54 , B01J2220/58 , B01J2220/82 , G01N30/463 , G01N30/466 , G01N30/482 , G01N30/7266 , G01N2030/528 , H01J49/0018 , H01J49/167
摘要： A microchip-based electrospray ionization device and column with affinity adsorbents is disclosed. The invention includes a microchip array.(2) and a capillary tube (1) or alone or attached in combination. At least a portion of the device or column has immobilized affinity adsorbents. Methods for using the device are provided as well for affinity capture of biomolecules to meet the needs for the modern life sciences such as proteomics and drug discover.
摘要翻译：公开了一种基于微芯片的电喷雾离子化装置和具有亲和吸附剂的柱。本发明包括微芯片阵列（2）和毛细管（1），或单独或组合连接。装置或柱的至少一部分具有固定的亲和吸附剂。还提供了使用该装置的方法用于生物分子的亲和捕获以满足现代生命科学如蛋白质组学和药物发现的需要。

8. 发明申请

WO02018928A2 CHROMATOGRAPHY AND OTHER ADSORPTIONS USING MODIFIED CARBON-CLAD METAL OXIDE PARTICLES 审中-公开
标题翻译：使用改性碳酸钙金属氧化物颗粒的色谱和其他吸附
公开(公告)号：WO02018928A2
公开(公告)日：2002-03-07
申请号：PCT/US2001/027060
申请日：2001-08-31
IPC分类号： B01D15/08 , B01D57/02 , B01D67/00 , B01D69/14 , B01D71/02 , B01D71/82 , B01J20/20 , B01J20/281 , B01J20/291 , B01J20/32 , G01N27/447 , G01N30/02 , G01N30/26 , G01N30/74 , G01N30/88 , G01N30/48
CPC分类号： B01D67/0093 , B01D15/08 , B01D57/02 , B01D69/141 , B01D71/021 , B01D71/024 , B01D71/82 , B01J20/06 , B01J20/20 , B01J20/286 , B01J20/287 , B01J20/29 , B01J20/3092 , B01J20/3204 , B01J20/3227 , B01J20/3244 , B01J20/3246 , B01J20/3253 , B01J20/3255 , B01J20/3272 , B01J20/3285 , B01J2220/42 , B01J2220/52 , B01J2220/54 , B01J2220/58 , B01J2220/825 , G01N27/44747
摘要： Separation devices and systems are described which have a stationary phase and a mobile phase, wherein the stationary phase contains carbon-clad zirconium dioxide particles having attached at least one organic group. The stationary phase which is used in the present invention has the ability to dial in the selectivity by attaching the proper organic groups onto the carbon-clad zirconium dioxide particles in order to achieve the desired separation. Various separation processes are described such as chromatography, electrophoresis, magnetic separations, membrane separations, and the like. The processes to accomplish these types of separations are also described.
摘要翻译：描述了具有固定相和流动相的分离装置和系统，其中固定相含有附着有至少一个有机基团的含碳二氧化锆颗粒。在本发明中使用的固定相具有通过将适当的有机基团附着在覆碳的二氧化锆颗粒上以选择性来拨号以实现期望的分离的能力。描述了各种分离方法，例如色谱法，电泳法，磁分离法，膜分离法等。还描述了完成这些类型的分离的过程。

9. 发明申请

WO01032760A1 A POROUS, MOLECULARLY IMPRINTED POLYMER AND A PROCESS FOR THE PREPARATION THEREOF 审中-公开
标题翻译：多分子分子量聚合物及其制备方法
公开(公告)号：WO01032760A1
公开(公告)日：2001-05-10
申请号：PCT/SE2000/002083
申请日：2000-10-26
IPC分类号： B01J20/281 , A61K9/16 , A61K9/52 , B01J20/26 , B01J20/28 , C07K17/14 , C08F6/00 , C08G85/00 , C08J9/26
CPC分类号： C08J9/26 , B01J20/268 , B01J20/28019 , B01J20/3057 , B01J2220/52 , C07K17/14 , C08J2201/0442
摘要： A porous, molecularly imprinted polymer and a process for its preparation are described. The porous, molecularly imprinted polymer is characterised in that it is obtainable by providing a porous silica; attaching a molecular template to the surface of the porous silica; filling the pores of the porous silica with a polymer; removing the silica and the molecular template, thereby leaving a porous, molecularly imprinted polymer. The process is characterised by the above defined process steps. Also described are a porous polymer vesicle and its preparation with the same features as defined for the porous, molecularly imprinted polymer and its preparation, except for the lack of the molecular template and thus the lack of the molecular imprint in the porous polymer.
摘要翻译：描述了多孔的分子印迹聚合物及其制备方法。多孔分子印迹聚合物的特征在于可通过提供多孔二氧化硅获得; 将分子模板附着到多孔二氧化硅的表面; 用聚合物填充多孔二氧化硅的孔; 除去二氧化硅和分子模板，从而留下多孔的分子印迹聚合物。该过程的特征在于上述定义的工艺步骤。还描述了多孔聚合物囊泡及其具有与多孔分子印迹聚合物及其制备所定义相同特征的制剂，不同之处在于缺少分子模板，因此在多孔聚合物中缺少分子印迹。

10. 发明申请

WO00071245A1 FOAMED MATERIAL FILLED WITH INNER MATERIAL 审中-公开
标题翻译：泡沫材料填充内部材料
公开(公告)号：WO00071245A1
公开(公告)日：2000-11-30
申请号：PCT/EP2000/004105
申请日：2000-05-08
IPC分类号： C12N11/10 , B01D15/08 , B01J20/24 , B01J20/26 , B01J20/28 , B01J20/281 , B01J20/285 , B01J20/286 , C12N11/08 , G01N30/48
CPC分类号： B01J20/286 , B01J20/26 , B01J20/28004 , B01J20/28014 , B01J20/28016 , B01J20/28023 , B01J20/28026 , B01J20/28042 , B01J20/28045 , B01J20/28085 , B01J20/28092 , B01J20/28095 , B01J20/28097 , B01J20/285 , B01J2220/52
摘要： A matrix comprising: a) a polymeric base matrix comprising macropores (pore system 1) and b) an interior material, possibly porous (pore system 2), retained within the macropores. The matrix is characterized in that there is a continuous free volume between the interior material and the pore walls of the macropores. A method for manufacturing a matrix comprising a base matrix having macropores in which an interior material is located. The method is characterized in comprising the steps: (i) providing a base matrix having macropores; (ii) filling the macropores with a soluble form of the interior material; (iii) transforming the insoluble form to an insoluble form; (iv) shrinking the insoluble form; and (v) irreversibly stabilising the material in its shrinked form. The matrix can be used in separation methods, cell culturing, solid phase synthesis of organic molecules, and in catalytic reactions (such as enzyme reactions) and other uses in which porous support matrices are used.
摘要翻译：一种基质，其包含：a）包含大孔（孔体系1）和b）保留在大孔内的内部材料（可能是多孔的（孔系统2））的聚合物基体基体。该基质的特征在于，在大孔的内部材料和孔壁之间存在连续的自由体积。一种制造基体的方法，其包括具有内部材料所在的大孔的基体基体。该方法的特征在于包括以下步骤：（i）提供具有大孔的基本矩阵; （ii）用可溶形式的内部材料填充大孔; （iii）将不溶形式转化为不溶形式; （iv）收缩不溶形式; 和（v）以其收缩的形式不可逆地稳定材料。该基质可用于分离方法，细胞培养，有机分子的固相合成，以及催化反应（如酶反应）以及使用多孔载体的其他用途。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式