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1. 发明申请

WO2010096651A2 DRUG DELIVERY DEVICE WITH IN-PLANE BANDPASS REGULATION CHECK VALVE IN HEAT-SHRINK PACKAGING 审中-公开
标题翻译：具有平面内压力调节装置的药物输送装置在热收缩包装中检查阀
公开(公告)号：WO2010096651A2
公开(公告)日：2010-08-26
申请号：PCT/US2010024730
申请日：2010-02-19
申请人： UNIV SOUTHERN CALIFORNIA , MENG ELLIS , MANN RONALEE LO
发明人： MENG ELLIS , MANN RONALEE LO
IPC分类号： A61M37/00 , A61M5/14 , A61M31/00 , A61M39/22
CPC分类号： A61M5/00 , A61F9/0017 , A61M5/14276 , A61M5/16881 , A61M2039/2413 , A61M2039/242 , A61M2210/0612
摘要： A drug delivery device may include a drug reservoir configured to contain and controllably deliver a fluidic drug. A tube may be configured to deliver the fluid from the drug reservoir through a lumen in the tube to another location. A valve wholly within the lumen of the tube may regulates the flow of the fluid through the tube without substantially diverting the direction in which the fluid flows through the tube. The valve may contain only a single member which moves during operation of the valve. The valve may be configured to regulate the flow of fluid in a bandpass manner by allowing fluid to flow through the valve only when the pressure of the fluid is above a minimum and below a maximum. The valve may be held in place within the tube solely by frictional force between the valve and a wall of the tube.
摘要翻译：药物递送装置可以包括被配置为容纳和可控地递送流体药物的药物储存器。管可以被配置成将来自药物储存器的流体通过管中的管腔输送到另一位置。完全在管腔中的阀可以调节流体通过管的流动，而不会使流体流过管的方向基本上转向。阀可以仅包含在阀操作期间移动的单个构件。阀可以被配置为通过仅当流体的压力高于最小值并且低于最大值时允许流体流过阀门才能以带通方式调节流体的流动。阀可以仅通过阀和管壁之间的摩擦力保持在管内的适当位置。

2. 发明申请

WO2016063710A1 バルブ、流体制御装置および血圧計审中-公开
标题翻译：阀，流体控制装置和血压计
公开(公告)号：WO2016063710A1
公开(公告)日：2016-04-28
申请号：PCT/JP2015/078139
申请日：2015-10-05
申请人：株式会社村田製作所
发明人：川村憲一郎
IPC分类号： A61B5/0235 , F04B43/04 , F16K7/17 , F16K15/14
CPC分类号： A61B5/0235 , A61M39/24 , A61M2039/2406 , A61M2039/2413 , A61M2039/2493 , F04B43/04 , F04B43/046 , F04B45/047 , F04B53/06 , F04B53/1087 , F16K7/17 , F16K15/144
摘要：　血圧計装置（１００）は、圧電ポンプ（１０）とバルブ（１０１）とカフ（１０９）とを備える。バルブ（１０１）は、第１弁筐体（１９１）とダイヤフラム（１２０）と第２弁筐体（１９２）とを備える。ダイヤフラム（１２０）は、弁座（１３９）と離間し、ダイヤフラム（１２０）における開口部（１２１）の周囲が弁座（１３８）を与圧して接触するよう、第２弁筐体（１９２）及び第１弁筐体（１９１）に固定されている。これにより、ダイヤフラム（１２０）は、第１通気孔（１１１）に連通する下バルブ室（１３１）と、第２通気孔（１１２）に連通する上バルブ室（１３３）と、第１通気孔（１１０）に連通する下バルブ室（１３２）と、上バルブ室（１３３）に連通する上バルブ室（１３４）とを、第２弁筐体（１９２）及び第１弁筐体（１９１）とともに構成する。
摘要翻译：血压计装置（100）装备有压电泵（10），阀（101）和袖带（109）。阀（101）配备有第一阀壳体（191），隔膜（120）和第二阀壳体（192）。膜片（120）固定到第二阀壳体（192）和第一阀壳体（191）上，使得隔膜（120）与阀座（139）和开口部分（121）的周边分开，隔膜（120）与阀座（138）接触并施加压力。由于这种结构，隔膜120与第二阀壳192和第一阀壳191一起构成与第一气孔111连通的下阀室131，与第二空气孔（112）连通的上部阀室（133），与第一空气孔（110）连通的下部阀室（132），以及上部阀室（134）与上阀室（133）连通。

3. 发明申请

WO2009062915A1 A VACUUM REGULATOR VALVE 审中-公开
标题翻译：真空调节阀
公开(公告)号：WO2009062915A1
公开(公告)日：2009-05-22
申请号：PCT/EP2008/065250
申请日：2008-11-10
申请人： IBERHOSPITEX, S.A. , DUOCASTELLA CODINA, Lluís , IDELSOHN ZIELONKA, Sebastián , FERNÁNDEZ SÁNCHEZ, David , LÓPEZ RODRÍGUEZ, Aniceto
发明人： DUOCASTELLA CODINA, Lluís , IDELSOHN ZIELONKA, Sebastián , FERNÁNDEZ SÁNCHEZ, David , LÓPEZ RODRÍGUEZ, Aniceto
IPC分类号： A61M1/00
CPC分类号： A61M1/0011 , A61M1/0035 , A61M2039/2413
摘要： It comprises a variable volume chamber (2) having a first opening (3) connectable to a vacuum source (40) and a second opening (4) connectable to a suction conduit (52; 36), such that, in use, the chamber (2) may be put in fluid communication with the vacuum source (40) and vacuum may be generated in the chamber to cause suction through the suction conduit (52; 36); the valve comprises a bellows (1; 1a) with at least one pleat, arranged to define the chamber (2) and operable to move, in use, between an expanded condition in which the first opening (3) of the chamber (2) remains open, and a contracted condition in which it causes the closure of the first opening (3). It constitutes a very simple and trouble-free device for draining a wound at a relatively low vacuum level using a high vacuum suction bottle.
摘要翻译：其包括具有可连接到真空源（40）的第一开口（3）和可连接到吸入管道（52; 36）的第二开口（4））的可变容积室（2），使得在使用中，室（2）可以与真空源（40）流体连通，并且可能在室中产生真空以通过吸入管道（52; 36）引起吸入; 所述阀包括具有至少一个褶皱的波纹管（1a; 1a），其布置成限定所述腔室（2）并且可操作以在使用中在所述腔室（2）的第一开口（3）的膨胀状态之间移动，保持开放状态，并导致关闭第一个开口（3）的合同条件。它构成了一种非常简单且无故障的装置，用于使用高真空抽吸瓶在相对较低的真空度下排出伤口。

4. 发明申请

WO2013135365A3 HOSE ADAPTER FOR INFLUENCING THE PRESSURE INSIDE A HOSE SECTION DURING A MEDICAL TREATMENT 审中-公开
标题翻译：软管接头影响到内管部分的压力。在医学治疗
公开(公告)号：WO2013135365A3
公开(公告)日：2014-04-03
申请号：PCT/EP2013000714
申请日：2013-03-11
申请人： FRESENIUS MEDICAL CARE DE GMBH
发明人： KLEWINGHAUS JUERGEN
IPC分类号： A61M39/22 , A61M1/16 , A61M5/168 , A61M39/10 , A61M39/24
CPC分类号： A61M39/10 , A61M1/166 , A61M5/16813 , A61M39/22 , A61M39/24 , A61M2039/2413 , A61M2039/242 , F04C2270/0421
摘要： The present invention relates to a hose adapter (100) for connection to at least one hose section (200) of a medical device. The invention further relates to a dialysate hose system having such a hose adapter, to a medical device having such a dialysate hose system, to a method for using the hose adapter according to the invention and to a method for preventing the occurrence of a pressure below a minimum pressure in a dialysate hose system.
摘要翻译：本发明涉及一种用于与医疗装置的至少一个管段（200）连接的软管接头（100）。本发明还涉及一种包括这种软管接头透析流体管道系统，具有这样的透析液管系统，根据本发明的和用于防止压力躺在下面在透析流体回路中的最小压力的发生的方法，使用的软管接头的方法的医疗装置。

5. 发明申请

WO2010048414A3 MINIATURE PUMP DEVICE WITH AN ANTI-FREE FLOW VALVE 审中-公开
标题翻译：具有防静电流量阀的微型泵装置
公开(公告)号：WO2010048414A3
公开(公告)日：2010-08-05
申请号：PCT/US2009061696
申请日：2009-10-22
申请人： STERLING INVEST LC , JACOBSEN STEPHEN C , OLSEN SHANE
发明人： JACOBSEN STEPHEN C , OLSEN SHANE
IPC分类号： A61M39/22 , A61M1/00
CPC分类号： A61M39/24 , A61M5/14216 , A61M5/16881 , A61M39/281 , A61M2039/2413 , F04B19/006 , F04B23/02 , F04B53/10 , F16K7/17 , Y10T137/7836
摘要： A miniature unidirectional valve configured to restrict the free flow of fluid through the valve includes a valve body having an inlet and an outlet. A flexible membrane is movably disposed over the inlet and outlet, and movable between an open position and a closed position. The flexible membrane is movable by a pressure from the inlet to move the membrane to the open position. A control chamber is disposed in the valve body adjacent the fluid flow path, and configured to apply a pressure against the membrane to move the membrane to the closed position to restrict fluid flow through the valve. A preload structure is associated with the flexible membrane, and biases the flexible membrane toward the closed position.
摘要翻译：构造成限制流体通过阀的自由流动的微型单向阀包括具有入口和出口的阀体。柔性膜可移动地设置在入口和出口上方，并且可在打开位置和关闭位置之间移动。柔性膜可以通过来自入口的压力移动以将膜移动到打开位置。控制室设置在阀体中邻近流体流动路径，并被配置为向膜施加压力以将膜移动到关闭位置以限制流过阀的流体流动。预加载结构与柔性膜相关联，并且将柔性膜偏向闭合位置。

6. 发明申请

WO2010048414A2 MINIATURE PUMP DEVICE WITH AN ANTI-FREE FLOW VALVE 审中-公开
标题翻译：微型泵装置，带有防自由流动阀
公开(公告)号：WO2010048414A2
公开(公告)日：2010-04-29
申请号：PCT/US2009/061696
申请日：2009-10-22
申请人： STERLING INVESTMENTS LC , JACOBSEN, Stephen, C. , OLSEN, Shane
发明人： JACOBSEN, Stephen, C. , OLSEN, Shane
IPC分类号： A61M39/22 , A61M1/00
CPC分类号： A61M39/24 , A61M5/14216 , A61M5/16881 , A61M39/281 , A61M2039/2413 , F04B19/006 , F04B23/02 , F04B53/10 , F16K7/17 , Y10T137/7836
摘要： A miniature unidirectional valve configured to restrict the free flow of fluid through the valve includes a valve body having an inlet and an outlet. A flexible membrane is movably disposed over the inlet and outlet, and movable between an open position and a closed position. The flexible membrane is movable by a pressure from the inlet to move the membrane to the open position. A control chamber is disposed in the valve body adjacent the fluid flow path, and configured to apply a pressure against the membrane to move the membrane to the closed position to restrict fluid flow through the valve. A preload structure is associated with the flexible membrane, and biases the flexible membrane toward the closed position.
摘要翻译：配置成限制流体通过阀的自由流动的微型单向阀包括具有入口和出口的阀体。柔性膜可移动地设置在入口和出口上方，并且可在打开位置和关闭位置之间移动。柔性膜可通过来自入口的压力移动，以将膜移动到打开位置。控制室邻近流体流动路径设置在阀体中，并配置成对膜施加压力以将膜移动到关闭位置以限制流体流过阀。预加载结构与柔性膜相关联，并将柔性膜偏向闭合位置。

7. 发明申请

WO03000329A3 FLOW REGULATOR FOR AEROSOL DRUG DELIVERY DEVICE AND METHODS 审中-公开
标题翻译：用于气溶胶药物递送装置的流调节剂和方法
公开(公告)号：WO03000329A3
公开(公告)日：2003-04-10
申请号：PCT/US0219388
申请日：2002-06-18
申请人： INHALE THERAPEUTIC SYST , ALSTON WILLIAM , SMEULDERS STEPHEN
发明人： ALSTON WILLIAM , SMEULDERS STEPHEN
IPC分类号： A61M13/00 , A61M15/00 , A61M16/20 , F16K15/14 , G05D7/06
CPC分类号： G05D7/012 , A61M15/0015 , A61M15/002 , A61M15/0091 , A61M15/0093 , A61M16/208 , A61M39/228 , A61M2039/2413 , A61M2202/064 , A61M2202/30 , F16K15/147
摘要： An aerosolization device comprises a housing having a mouthpiece, and a flow path arrangement in fluid communication with the mouthpiece. The flow path arrangement has a flow regulating valve and a threshold valve, where the threshold valve is configured to open at a first vacuum level and to close at a second vacuum level that is less than the first vacuum level. The housing includes a region that is adapted to hold a powder in fluid communication with the flow path arrangement so that air drawn through the mouthpiece opens the threshold valve once the first vacuum level is exceeded and remains open until the vacuum falls below the second vacuum level. The flow rate of the air drawn through the mouthpiece is regulated by the flow regulating valve to remain within a certain range while the threshold valve remains open.
摘要翻译：雾化装置包括具有接口管的壳体和与接口管流体连通的流路装置。流动路径装置具有流量调节阀和阈值阀，其中阈值阀配置成在第一真空水平下打开并且在小于第一真空水平的第二真空水平下关闭。壳体包括适于保持与流动路径装置流体连通的粉末的区域，使得一旦超过第一真空水平，通过接口管抽出的空气打开阈值阀并保持打开，直到真空降至第二真空水平以下。通过接口管吸入的空气的流量由流量调节阀调节，保持在一定范围内，同时阈值阀保持打开。

8. 发明申请

WO2014110022A4 FLOW ACTUATED VALVE FOR IMPLANTABLE DRUG DELIVERY DEVICE 审中-公开
标题翻译：用于可植入药物输送装置的流动致动阀
公开(公告)号：WO2014110022A4
公开(公告)日：2014-09-18
申请号：PCT/US2014010465
申请日：2014-01-07
申请人： FLOWONIX MEDICAL INC
发明人： BURKE PAUL , ADLER STEVE , PIECUCH BENJAMIN , HANTMAN STEVE
IPC分类号： A61M5/14 , A61M39/22
CPC分类号： A61M5/16881 , A61M5/14276 , A61M2039/2413 , A61M2039/242 , A61M2039/2433 , A61M2039/2466 , A61M2039/2473
摘要： An "MRI-safe" implantable infusion apparatus and method that includes a flow actuated valve (FAV) that closes to prevent a free flow of infusate to a patient during an MRI procedure, and a release mechanism that opens the valve so that the device may return to normal operation following the MRI procedure. In this manner, patient safety is improved and the inconvenience of having to empty the pump reservoir before undergoing an MRI procedure may be avoided.
摘要翻译：一种“MRI安全的”植入式输注装置和方法，其包括关闭流动致动阀（FAV），以防止在MRI过程期间向患者自由流动的患者;以及释放机构，其打开所述阀，使得所述装置可 MRI程序恢复正常。以这种方式，可以改善患者的安全性，并且可以避免在经历MRI过程之前清空泵储存器的不便。

9. 发明申请

WO2013173127A1 FLOW REGULATION VALVE FOR CONTROLLING INFLATION RATE OF A BALLOON DEPLOYING A SCAFFOLD 审中-公开
标题翻译：流量调节阀，用于控制分配给SCAFFOLD的气瓶的充气速率
公开(公告)号：WO2013173127A1
公开(公告)日：2013-11-21
申请号：PCT/US2013/039980
申请日：2013-05-07
申请人： ABBOTT CARDIOVASCULAR SYSTEMS INC. , PACETTI, Stephen D. , WANG, Yunbing
发明人： PACETTI, Stephen D. , WANG, Yunbing
IPC分类号： A61F2/958 , A61M25/10
CPC分类号： A61F2/958 , A61M5/16877 , A61M25/10184 , A61M25/10185 , A61M25/104 , A61M39/24 , A61M2039/2413
摘要： An apparatus and method for controlling inflation pressure, pressurization rate, and volumetric flow rate of a balloon during deployment of a stent or scaffold is disclosed. The apparatus includes a valve (200, 300) that has a flow restrictor (228, 328) that limits flow of inflation fluid into the balloon to a maximum value and provides essentially no resistance upon deflation of the baloon.
摘要翻译：公开了一种用于在展开支架或支架期间控制气囊的充气压力，加压速率和体积流量的装置和方法。该装置包括具有限流器（228,328）的阀门（200,300），该限流器限制膨胀流体进入球囊的流量达到最大值，并且在气球放气时基本上不产生阻力。

10. 发明申请

WO2011098946A1 MICROMECHANIC PASSIVE FLOW REGULATOR 审中-公开
标题翻译：微生物被动流量调节器
公开(公告)号：WO2011098946A1
公开(公告)日：2011-08-18
申请号：PCT/IB2011/050514
申请日：2011-02-07
申请人： DEBIOTECH S.A. , CHAPPEL, Eric
发明人： CHAPPEL, Eric
IPC分类号： A61M5/168 , A61M27/00 , F15C3/04 , F15C5/00 , F16K11/00 , G05D7/01 , F16K99/00
CPC分类号： A61M5/16881 , A61M5/14276 , A61M5/145 , A61M5/16813 , A61M27/006 , A61M2039/2413 , A61M2205/0244 , F16K99/0001 , F16K99/0015 , F16K99/0057 , F16K2099/008 , F16K2099/0088 , G05D7/0635 , G05D7/0694 , Y10T137/7791 , Y10T137/86734
摘要： The invention concerns a flow regulator, made of a stack of 3 plates, respectively a top plate including a flexible membrane (1), a middle plate (2) with pillars and through holes and a bottom plate ( 3 ) with fluidic ports, micro channels and through holes (8,9,12). The principle is based on the deformation of the membrane due to the pressure of the liquid. The membrane goes in contact with the pillars of the middle plate, obstructing gradually the through holes of the pillars. The device is designed to keep the flow constant in a predefined range of pressure. The device is dedicated to ultra low flow rate up to 1 ml per day or below, typically for drug infusion. Plastic flow regulators comprise preferably several independent valves coupled in parallel. The membrane plate is therefore made of several flexible membranes obstructing gradually the flow by increasing the pressure. Stress limiters are used to avoid plastic deformation of the membrane. For implanted pump, the use of a flow regulator instead of a flow restrictor has several advantages, including the possibility to reduce significantly the reservoir pressure and to generate directly the pressure during the pump filling by using an elastic drug reservoir.
摘要翻译：本发明涉及一种流量调节器，由三个板组成，分别是包括柔性膜（1），具有支柱和通孔的中间板（2）和具有流体端口的底板（3）的顶板，微板通道和通孔（8,9,12）。该原理是基于液体由于压力引起的膜的变形。膜与中间板的支柱接触，逐渐阻塞柱的通孔。设备旨在使流量保持在预定的压力范围内。该设备专用于每天或以下超过1毫升的超低流速，通常用于药物输注。塑料流量调节器优选并联连接多个独立的阀。因此，膜片由几个柔性膜制成，通过增加压力逐渐阻塞流动。应力限制器用于避免膜的塑性变形。对于植入式泵，使用流量调节器代替限流器具有若干优点，包括显着降低储层压力并通过使用弹性药物储存器在泵填充期间直接产生压力的可能性。

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