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1. 发明申请

WO2023085144A1 投与装置审中-公开
公开(公告)号：WO2023085144A1
公开(公告)日：2023-05-19
申请号：PCT/JP2022/040617
申请日：2022-10-31
申请人：テルモ株式会社
发明人：吉川　弘樹 , 畑　優 , 山本　聡
IPC分类号： A61M31/00 , A61M5/142
摘要：【課題】生体管腔内に留置する際に、十分な投与物の収容量を確保しつつ生体管腔を損傷することなく目的の留置位置まで容易に搬送すること。【解決手段】生体管腔内に留置され、収容する投与物Ｘを放出する装置であって、投与物Ｘを収容する内腔１１を有し、外力に抗して内腔１１の形状が保持可能に構成される筒状の本体部１０と、内腔１１内を液密に摺動可能な押出部４０と、を備え、本体部１０は、少なくとも一部が生体管腔の形状に沿って変形可能な変形部材で構成される。

2. 发明申请

WO2023073176A1 DRUG DELIVERY DEVICE WITH OFFSET ACTUATOR MECHANISM 审中-公开
公开(公告)号：WO2023073176A1
公开(公告)日：2023-05-04
申请号：PCT/EP2022/080211
申请日：2022-10-28
申请人： BIOGRAIL APS
发明人： SKAK, Nikolaj , LINDHARDT, Karsten , ERICHSEN, Kamille Majken Dumong
IPC分类号： A61M31/00 , A61M5/142
摘要： A drug delivery device comprising a central axis extending from a first longitudinal end of the drug delivery device to a second longitudinal end of the drug delivery device, a first body part, a second body part, an attachment part connected to the first body part, and an actuator mechanism configured to rotate one of the first body part and/or the second body part, wherein the actuator mechanism is located more towards the first longitudinal end than the second longitudinal end along the central axis.

3. 发明申请

WO2023071022A1 植入式液体转运装置及液体转运控制系统审中-公开
公开(公告)号：WO2023071022A1
公开(公告)日：2023-05-04
申请号：PCT/CN2022/080798
申请日：2022-03-14
申请人：浙江清华柔性电子技术研究院 , 上海歌瑞盟医疗器械技术有限公司
发明人：曾金 , 付际 , 王智勇
IPC分类号： A61M1/00 , A61M27/00 , A61M31/00 , A61B10/00
摘要：一种植入式液体转运装置及液体转运控制系统，植入式液体转运装置包括泵体(11)、控制阀(101)、进液管(15)以及出液管(16)，控制阀(101)包括第一控制阀(13)和第二控制阀(14)，进液管(15)的一端与泵体(11)的一端连接，出液管(16)的一端与泵体(11)的另一端连接，泵体(11)用于驱动体液从进液管(15)流向出液管(16)，出液管(16)的另一端设有多个分歧管(160)，第一控制阀(13)设于进液管(15)上，第二控制阀(14)设于出液管(16)上，第二控制阀(14)为多通阀并用于控制出液管(16)与分歧管(160)导通，多个分歧管(160)分别设于不同的组织处。植入式液体转运装置避免了反复穿刺的感染，对腹水患者的普适性较好；而且多个分歧管(160)的设计可用于转运液体，给药治疗或取样检测，及对肿瘤等恶化及含炎性因子的液体，引流至体外。

4. 发明申请

WO2023049095A1 REFILLABLE IMPLANTABLE DEVICE FOR DELIVERING A DRUG COMPOUND 审中-公开
公开(公告)号：WO2023049095A1
公开(公告)日：2023-03-30
申请号：PCT/US2022/044081
申请日：2022-09-20
申请人： CELANESE EVA PERFORMANCE POLYMERS LLC
发明人： GYANANI, Vijay , HALEY, Jeffrey , HENRY, Keith , WELSH, Kevin
IPC分类号： A61K9/00 , A61M31/00 , A61M37/00 , A61F2/02
摘要： An implantable and refillable device for delivering a drug compound is provided. The device comprises a reservoir within which the drug compound is capable of being retained, wherein the reservoir defines a first surface and a second surface opposing the first surface. A release structure comprising a hydrophobic polymer surrounds at least a portion of the reservoir. The release structure is in communication with the reservoir such that the drug compound can pass from the reservoir through the release structure. A septum is positioned adjacent to the first surface of the reservoir and a backing layer is positioned adjacent to the second surface of the reservoir.

5. 发明申请

WO2023043908A1 BIOACTIVE RELEASING MEMBRANE FOR ANALYTE SENSOR 审中-公开
公开(公告)号：WO2023043908A1
公开(公告)日：2023-03-23
申请号：PCT/US2022/043641
申请日：2022-09-15
申请人： WANG, Shanger , AVULA, Mahender Nath , DRING, Chris , LEE, Ted Tang , LIU, Xiangyou , PARNELL, Shane Richard , ZOU, Jiong , DEXCOM, INC.
发明人： WANG, Shanger , AVULA, Mahender Nath , DRING, Chris , LEE, Ted Tang , LIU, Xiangyou , PARNELL, Shane Richard , ZOU, Jiong
IPC分类号： A61B5/145 , A61B5/1459 , A61B5/1473 , A61B5/1486 , A61L31/10 , A61L31/16 , A61K9/00 , A61M31/00
摘要： The present disclosure relates generally to bioactive releasing membranes utilized with implantable devices, such as devices for the detection of analyte concentrations in a biological sample. More particularly, the disclosure relates to novel bioactive releasing membranes, to devices and implantable devices including these membranes, methods for forming the bioactive releasing membranes on or around the implantable devices, and to methods for monitoring analyte levels in a biological fluid sample using an implantable analyte detection device.

6. 发明申请

WO2023037373A1 DEVICE FOR VAGINAL TISSUE TREATMENT 审中-公开
公开(公告)号：WO2023037373A1
公开(公告)日：2023-03-16
申请号：PCT/IL2022/050985
申请日：2022-09-12
申请人： REDDRESS LTD.
发明人： KUSHNIR, Alon , KUSHNIR, Igal
IPC分类号： A61M31/00 , A61B17/00 , A61B17/42
摘要： The present invention relates to a device (100) for treating a vaginal lesion, by forming a coagulated blood mass, which is introduced by the device (100) into the vagina. The device (100) comprises an elongated guiding tube (102) having a lumen (104) for receiving whole blood and a plunger (112) having a piston element (114) fitted within the lumen (104) thus defining a blood coagulating space (109) between it and a blood-introducing end (106). The guiding tube (102) is configured for being introduced into the vagina and to discharge a coagulating blood mass formed within the lumen (104), in result of displacement of the displaceable piston (114) element.The coagulated blood mass may be maintained in the vagina by an anchoring element (122) configured to expand within the vagina and maintain there for a desired time and then be retrieved. Methods of treatment are also disclosed.

7. 发明申请

WO2023036296A1 一种给药胶囊审中-公开
公开(公告)号：WO2023036296A1
公开(公告)日：2023-03-16
申请号：PCT/CN2022/118123
申请日：2022-09-09
申请人：安翰科技（武汉）股份有限公司
发明人：杨戴天杙 , 包宇晖 , 明繁华 , 彭航宇 , 王新宏 , 段晓东 , 肖国华
IPC分类号： A61M31/00
摘要：一种给药胶囊，具有药仓(10)的壳体(1)、设置在药仓(10)内的软囊(11)、给药通道(2)和给药控制模块(3)；给药控制模块(3)用于向药仓(10)内充填流体以实现对软囊(11)的挤压，从而采用以置换的方式给药，通过控制进入到药仓(10)内流体的量进而实现控制给药的量，通过控制进入到药仓(10)内的流体的速度进而实现给药的速度的控制。

8. 发明申请

WO2023031711A1 CURED RING SEAL 审中-公开
公开(公告)号：WO2023031711A1
公开(公告)日：2023-03-09
申请号：PCT/IB2022/057557
申请日：2022-08-12
申请人： COCHLEAR LIMITED
发明人： KIRK, Jonathon
IPC分类号： A61N1/375 , A61N1/36 , A61N1/05 , A61M31/00
摘要： Presented herein are cured ring seals and related methods for at least temporarily sealing openings in fluidically-sealed body chambers. The cured ring seals include a body that is formed from a hydrophilic or hygroscopic polymer, such as polyvinyl alcohol (PVA), that is cured prior to implantation into the body of a recipient (e.g., pre-cured). The cured ring seals are substantially pliable to facilitate positioning around an outer surface of an implantable component and are configured to expand following implantation.

9. 发明申请

WO2023026240A1 INNER EAR ACCESS DETERMINATION 审中-公开
公开(公告)号：WO2023026240A1
公开(公告)日：2023-03-02
申请号：PCT/IB2022/057989
申请日：2022-08-26
申请人： COCHLEAR LIMITED
发明人： DUECK, Wolfram Frederik , SMYTH, Daniel
IPC分类号： A61M31/00 , A61F2/18 , G16H20/17
摘要： A method including entering a fluid containing cavity in a human with an artificial device, verifying that a portion of the artificial device has entered the fluid containing cavity based on an electrical phenomenon indicative of a sensor component supported by and/or part of the artificial device being located in the fluid containing cavity.

10. 发明申请

WO2023009150A1 THERAPEUTIC SWABS FOR TREATING UPPER RESPIRATORY INFECTIONS 审中-公开
公开(公告)号：WO2023009150A1
公开(公告)日：2023-02-02
申请号：PCT/US2021/049986
申请日：2021-09-13
申请人： DHAWAN, Subhash
发明人： DHAWAN, Subhash
IPC分类号： A61J7/00 , A61M31/00
摘要： The present invention offers Therapeutic Swabs device system as the first therapeutic approach intended to deliver plurality of antiviral, antimicrobial, cytoproteclive, anti-inflammatory, and low- or non-anticoagulant drugs to the nasal and oral cavities, nasopharynx, and posterior pharynx, the primary sites of upper respiratory infections. This invention enables an ideal multiprong therapeutic approach for effective targeting of serious upper respiratory infections in the humans and in animals. By virtue of the unique configuration of the Therapeutic Swabs device system comprising multiple drugs with distinctive functions, this system is highly desirable to maximize protection against deadly respiratory infections, including SARS-CoV-2, yet alleviating the undesired adverse side effects associated with systemic absorption of drugs administered via other routes. Since the upper respiratory disease-causing pathogens spread primarily through breathing, droplets of saliva, discharge from nasal secretions, or via other direct contacts, this invention offers a useful broadly applicable therapeutic approach to effectively control the current out-of-control COVID-19 pandemic and future viral outbreaks, and can be utilized by healthcare professionals, other individuals, friends and family members, or even by self-administration on a mass-scale.

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