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1. 发明申请

WO2017024258A1 AXIALLY LENGTHENING THROMBUS CAPTURE SYSTEM 审中-公开
标题翻译：轴向增加血栓捕获系统
公开(公告)号：WO2017024258A1
公开(公告)日：2017-02-09
申请号：PCT/US2016/045862
申请日：2016-08-05
申请人： KP MEDCURE, INC.
发明人： NGUYEN, Thanh, Van , NGUYEN, Duy , NGO, Tung, H.
IPC分类号： A61B17/22 , A61F2/00 , A61M25/00
CPC分类号： A61B17/221 , A61B17/320758 , A61B2017/00867 , A61B2017/00871 , A61B2017/00893 , A61B2017/00938 , A61B2017/00942 , A61B2017/22038 , A61B2017/22079 , A61B2017/22081 , A61B2017/22084 , A61B2017/2212 , A61B2017/2217 , A61B2017/320052 , A61B2017/320716 , A61B2017/320775 , A61F2/013 , A61F2002/011 , A61F2002/016
摘要： Disclosed herein are systems and methods to remove material of interest, including blood clots, from a body region, including but not limited to the circulatory system for the treatment of pulmonary embolism (PE), deep vein thrombosis (DVT), cerebrovascular embolism, and other vascular occlusions.
摘要翻译：本文公开了从身体区域中除去包括血凝块在内的感兴趣材料（包括血块）的系统和方法，包括但不限于用于治疗肺栓塞（PE），深静脉血栓形成（DVT），脑血管栓塞的循环系统其他血管闭塞。

2. 发明申请

WO2005034793A2 APPARATUS AND METHOD FOR AN ULTRASONIC MEDICAL DEVICE WITH A NON-COMPLIANT BALLOON 审中-公开
标题翻译：具有非合并气囊的超声医疗装置的装置和方法
公开(公告)号：WO2005034793A2
公开(公告)日：2005-04-21
申请号：PCT/US2004/015331
申请日：2004-05-14
申请人： OMNISONICS MEDICAL TECHNOLOGIES, INC. , HARE, Bradley, A. , RABINER, Robert, A.
发明人： HARE, Bradley, A. , RABINER, Robert, A.
IPC分类号： A61F
CPC分类号： A61B17/22004 , A61B17/22012 , A61B17/320068 , A61B2017/00137 , A61B2017/00274 , A61B2017/00778 , A61B2017/22007 , A61B2017/22008 , A61B2017/22015 , A61B2017/22018 , A61B2017/22028 , A61B2017/22051 , A61B2017/22081 , A61B2017/320084 , A61B2018/00547 , A61B2018/00982 , A61B2217/005 , A61B2217/007 , A61M1/0084 , A61N7/022
摘要： The present invention provides an apparatus and a method for an ultrasonic medical device (11) with a non-compliant balloon (41) used to ablate a biological material. The ultrasonic medical device (11)comprises an ultrasonic probe (15), a catheter (36) surrounding the ultrasonic probe (15), a balloon (41) supported by the catheter (36) and an inflation lumen (85) located along a longitudinal axis of the catheter (36). The ultrasonic probe (15) is inserted into a vasculature (44) and the catheter (36) comprising the balloon (41) is advanced until the balloon (41) is adjacent to the biological material. The balloon (41) is inflated until at least a portion of an outer surface (53) of the balloon (41) engages the biological material. The ultrasonic probe (15) is energized to produce a transverse ultrasonic vibration that vibrates at least a portion of the balloon (41) to ablate the biological material into a particulate.
摘要翻译：本发明提供一种具有用于烧蚀生物材料的非顺应性球囊（41）的超声波医疗装置（11）的装置和方法。超声波医疗装置（11）包括超声波探头（15），围绕超声波探头（15）的导管（36），由导管（36）支撑的球囊（41）和沿着导管（36）的纵向轴线。将超声波探头（15）插入脉管系统（44）中，并且包括球囊（41）的导管（36）前进直到球囊（41）与生物材料相邻。气球（41）被充气，直到球囊（41）的外表面（53）的至少一部分与生物材料接合。超声波探头（15）被通电以产生横向超声波振动，该振动振动至少一部分球囊（41）以将生物材料烧蚀成颗粒。

3. 发明申请

WO2014081892A1 METHODS AND APPARATUS FOR TREATING EMBOLISM 审中-公开
标题翻译：治疗手术的方法和装置
公开(公告)号：WO2014081892A1
公开(公告)日：2014-05-30
申请号：PCT/US2013/071101
申请日：2013-11-20
申请人： ROSENBLUTH, Robert , COX, Brian, J. , LUBOCK, Paul , QUICK, Richard
发明人： ROSENBLUTH, Robert , COX, Brian, J. , LUBOCK, Paul , QUICK, Richard
IPC分类号： A61M25/01 , A61M25/08 , A61M25/09
CPC分类号： A61B17/320725 , A61B17/22 , A61B17/22032 , A61B17/221 , A61B17/32075 , A61B2017/00809 , A61B2017/00862 , A61B2017/00867 , A61B2017/22034 , A61B2017/22038 , A61B2017/22081 , A61B2017/22094 , A61B2017/320716 , A61B2217/005 , A61M39/04
摘要： A method and apparatus for treating a clot in the blood vessel of a patient, and particularly the treatment of a pulmonary embolism is disclosed. The treatment includes restoring flow through the clot followed by clot removal, either partially or substantially completely. The clot treatment device is expandable into the blood vessel and may contain radial extensions that assist in restoring flow as well as in removing clot material.
摘要翻译：公开了一种治疗患者血管中凝块的方法和装置，特别是治疗肺栓塞。治疗包括恢复血块，然后部分或基本上完全去除血块。凝块治疗装置可扩张到血管中并且可以包含有助于恢复流动以及去除凝块材料的径向延伸部。

4. 发明申请

WO2012052922A1 AN ULTRASOUND TRANSCEIVER AND USES THEREOF 审中-公开
标题翻译：超声波收发器及其用途
公开(公告)号：WO2012052922A1
公开(公告)日：2012-04-26
申请号：PCT/IB2011/054636
申请日：2011-10-18
申请人： CARDIOSONIC LTD. , SVERDLIK, Ariel , SHABTAY, Or
发明人： SVERDLIK, Ariel , SHABTAY, Or
IPC分类号： A61B17/22 , A61N7/00 , G01S15/89
CPC分类号： A61B17/320068 , A61B17/2202 , A61B2017/00106 , A61B2017/22008 , A61B2017/22051 , A61B2017/22081 , A61B2090/378 , A61M37/0092 , A61N7/02 , A61N7/022 , A61N2007/0078
摘要： A dual use ultrasonic transceiver device for combined sensing and power transmission, comprises a first piezoelectric transceiver sized for placement in a body lumen; a power unit enabling an ultrasonic power beam for thermal tissue damage or ablation in a tissue ablation region; and a sensing unit enabling an ultrasonic sensing beam for sensing at said tissue ablation region. In one example, a single piezoelectric surface is electrically connected to a mounting; and the mounting provides a first region of the piezoelectric surface with a first relatively high level of damping and a second region of said piezoelectric surface with a second relatively low level of damping, thereby to enable sensing from said first region and power transmission from said second region. Changes in efficiency of the transceiver or the treatment during use may be inferred from changes in the impulse response or impedance or changes in the temperature of liquids that have flowed past the transceiver.
摘要翻译：一种用于组合感测和电力传输的双重用途超声波收发器装置，包括尺寸适于放置在体腔中的第一压电收发器; 功率单元，其能够使超声波功率束用于组织消融区域中的热组织损伤或消融; 以及感测单元，其使得能够在所述组织消融区域感测的超声波感测光束。在一个示例中，单个压电表面电连接到安装件; 并且所述安装件提供具有第一相对高水平的阻尼的所述压电表面的第一区域和所述压电表面的第二区域，具有第二相对低水平的阻尼，从而能够从所述第一区域感测和从所述第二区域的电力传输地区。收发器效率的变化或使用过程中的处理可以通过脉冲响应或阻抗的变化或已经流经收发器的液体的温度变化来推断。

5. 发明申请

WO2008102363A2 TREATING WEAKENED VESSEL WALL SUCH AS VULNERABLE PLAQUE OR ANEURYSMS 审中-公开
标题翻译：处理弱化的船只等作为易受伤害的人群或风险
公开(公告)号：WO2008102363A2
公开(公告)日：2008-08-28
申请号：PCT/IL2008/000234
申请日：2008-02-21
申请人： RAMOT AT TEL AVIV UNIVERSITY LTD. , SVERDLIK, Ariel , EINAV, Shmuel , ARONIS, Zeev , KORNOWSKI, Ran , LEVI, Ifat
发明人： SVERDLIK, Ariel , EINAV, Shmuel , ARONIS, Zeev , KORNOWSKI, Ran , LEVI, Ifat
IPC分类号： A61F2/02
CPC分类号： A61N7/00 , A61B5/0048 , A61B8/485 , A61B2017/00106 , A61B2017/22001 , A61B2017/22081 , A61N2007/0078
摘要： Described is a method of stabilizing blood vessel wall abnormality. The method includes ultrasonically heating at least a portion of the blood vessel wall having the abnormality; monitoring a parameter related to a property of at least a portion of the heated portion of the blood vessel wall; and stopping the heating when the monitored parameter changes by a predetermined factor or after the monitored parameter changes in a slow enough rate. The slow enough rate may be, for instance, a predetermined fraction of a maximal rate change observed during heating.
摘要翻译：描述了一种稳定血管壁异常的方法。该方法包括对具有异常的血管壁的至少一部分进行超声波加热; 监测与血管壁的加热部分的至少一部分的性质相关的参数; 并且当所监视的参数改变预定因子时或在所监视的参数以足够慢的速率改变之后停止加热。足够慢的速率可以是例如在加热期间观察到的最大速率变化的预定分数。

6. 发明申请

WO2005034793A3 APPARATUS AND METHOD FOR AN ULTRASONIC MEDICAL DEVICE WITH A NON-COMPLIANT BALLOON 审中-公开
标题翻译：用于具有非符合球囊的超声医疗装置的装置和方法
公开(公告)号：WO2005034793A3
公开(公告)日：2005-08-11
申请号：PCT/US2004015331
申请日：2004-05-14
申请人： OMNISONICS MEDICAL TECH , HARE BRADLEY A , RABINER ROBERT A
发明人： HARE BRADLEY A , RABINER ROBERT A
IPC分类号： A61B20060101 , A61B17/00 , A61B17/22 , A61B17/32 , A61B18/00 , A61F20060101 , A61M1/00 , A61N7/00 , A61N7/02
CPC分类号： A61B17/22004 , A61B17/22012 , A61B17/320068 , A61B2017/00137 , A61B2017/00274 , A61B2017/00778 , A61B2017/22007 , A61B2017/22008 , A61B2017/22015 , A61B2017/22018 , A61B2017/22028 , A61B2017/22051 , A61B2017/22081 , A61B2017/320084 , A61B2018/00547 , A61B2018/00982 , A61B2217/005 , A61B2217/007 , A61M1/0084 , A61N7/022
摘要： The present invention provides an apparatus and a method for an ultrasonic medical device (11) with a non-compliant balloon (41) used to ablate a biological material. The ultrasonic medical device (11)comprises an ultrasonic probe (15), a catheter (36) surrounding the ultrasonic probe (15), a balloon (41) supported by the catheter (36) and an inflation lumen (85) located along a longitudinal axis of the catheter (36). The ultrasonic probe (15) is inserted into a vasculature (44) and the catheter (36) comprising the balloon (41) is advanced until the balloon (41) is adjacent to the biological material. The balloon (41) is inflated until at least a portion of an outer surface (53) of the balloon (41) engages the biological material. The ultrasonic probe (15) is energized to produce a transverse ultrasonic vibration that vibrates at least a portion of the balloon (41) to ablate the biological material into a particulate.
摘要翻译：本发明提供了一种用于具有用于消融生物材料的非顺应性球囊（41）的超声医疗装置（11）的设备和方法。超声波医疗装置（11）包括超声波探头（15），围绕超声波探头（15）的导管（36），由导管（36）支撑的气囊（41）和沿着导管（36）的纵向轴线。将超声探头（15）插入脉管系统（44），并且包括气囊（41）的导管（36）前进，直到气囊（41）与生物材料相邻。球囊（41）膨胀直到球囊（41）的外表面（53）的至少一部分接合生物材料。超声波探头（15）通电以产生横向超声波振动，振动至少一部分球囊（41）以将生物材料烧蚀成颗粒。

7. 发明申请

WO2003059179A1 ASPIRATING BALLOON CATHETER FOR TREATING VULNERABLE PLAQUE 审中-公开
标题翻译：用于处理易燃液体的吸入式气体导管
公开(公告)号：WO2003059179A1
公开(公告)日：2003-07-24
申请号：PCT/US2003/000409
申请日：2003-01-07
申请人： SCIMED LIFE SYSTEMS, INC.
发明人： DOBRAVA, Eric, M. , KOKATE, Jaydeep, Y.
IPC分类号： A61B17/22
CPC分类号： A61M25/104 , A61B17/22 , A61B17/320708 , A61B2017/22079 , A61B2017/22081 , A61B2217/005 , A61M2025/1013 , A61M2025/1072 , A61M2025/1075 , A61M2025/109
摘要： Devices and methods for extracting core material contained in plaque deposits inside a blood vessel are presented. A device in accordance with one embodiment of the invention includes a catheter having an elongate shaft, a collection array of a plurality of collection lumens disposed about the distal portion of the elongate shaft, a means for radially extending and/or collapsing the collection array, and a suction means for extracting material from the lumen of the blood vessel. A method in accordance with one embodiment of the present invention includes the steps of inserting the distal portion of the catheter into a lumen of the blood vessel, positioning the distal end of the collection array proximate plaque deposits, extending the collection array to rupture the plaque deposits and urging core material therefrom, and extracting the material using a suction means fluidly coupled to the proximal end of the collection array.
摘要翻译：提出了用于提取包含在血管内的斑块沉积物中的核心材料的装置和方法。根据本发明的一个实施例的装置包括具有细长轴的导管，围绕细长轴的远端部分设置的多个收集腔的收集阵列，用于径向延伸和/或收缩收集阵列的装置，以及用于从血管的内腔提取物质的抽吸装置。根据本发明的一个实施例的方法包括以下步骤：将导管的远端部分插入血管的内腔，将收集阵列的远端靠近斑块沉积物，延伸收集阵列以破裂斑块沉积和推动芯材，并且使用流体耦合到收集阵列的近端的抽吸装置提取材料。

8. 发明申请

WO2015017499A1 DEVICE FOR GENERATING SHOCKWAVES 审中-公开
标题翻译：用于产生震荡的装置
公开(公告)号：WO2015017499A1
公开(公告)日：2015-02-05
申请号：PCT/US2014/048794
申请日：2014-07-30
申请人： SHOCKWAVE MEDICAL, INC.
发明人： HAWKINS, Daniel
IPC分类号： A61B17/22
CPC分类号： A61B17/22022 , A61B17/2202 , A61B17/22029 , A61B18/1492 , A61B2017/00526 , A61B2017/22025 , A61B2017/22027 , A61B2017/22028 , A61B2017/22062 , A61B2017/22081 , A61B2017/22098 , A61B2018/1405 , A61N7/022 , Y10T29/49201
摘要： Described here are angioplasty balloon devices for generating shock waves to break up calcified plaques along a length of a vessel and methods of making such devices. Generally, the devices may be used in angioplasty and/or valvuloplasty procedures, but may alternatively be used in other applications. In some variations, the device may include an elongate member, a plurality of electrode assemblies, and at least one tubular sleeve interposed between adjacent or neighboring electrode assemblies that form a continuous outer profile between the electrode assemblies. These devices may have a smooth, continuous outer profile without substantial profile transitions and/or may have stiffening sections between electrode assemblies.
摘要翻译：这里描述了用于产生冲击波以沿着血管长度分解钙化斑块的血管成形术球囊装置和制造这种装置的方法。通常，所述装置可用于血管成形术和/或瓣膜成形术程序中，但也可替代地用于其它应用。在一些变型中，该装置可以包括细长构件，多个电极组件和插入相邻或相邻电极组件之间的至少一个管状套管，其在电极组件之间形成连续的外部轮廓。这些装置可以具有光滑的，连续的外部轮廓，而没有实质的轮廓转移和/或可以在电极组件之间具有加强部分。

9. 发明申请

WO2013112768A1 ENDOLUMINAL DEVICE AND METHOD 审中-公开
标题翻译：内镜装置和方法
公开(公告)号：WO2013112768A1
公开(公告)日：2013-08-01
申请号：PCT/US2013/023030
申请日：2013-01-24
申请人： INTACT VASCULAR, INC.
发明人： GIASOLLI, Robert, M. , SCHNEIDER, Peter
IPC分类号： A61F2/06
CPC分类号： A61F2/848 , A61B17/064 , A61B17/068 , A61B17/07207 , A61B2017/0641 , A61B2017/22081 , A61B2017/2937 , A61B2090/0807 , A61B2090/3966 , A61F2/82 , A61F2/844 , A61F2/86 , A61F2/91 , A61F2/915 , A61F2/92 , A61F2/962 , A61F2/966 , A61F2002/823 , A61F2002/825 , A61F2002/826 , A61F2002/8483 , A61F2002/8486 , A61F2002/91508 , A61F2002/9517 , A61F2002/9583 , A61F2220/0016 , A61F2230/0065 , A61F2250/001 , A61F2250/0039 , A61F2250/0062
摘要： An endoluminal device can be configured for precise positioning during deployment within a vessel. The endoluminal device can be a tack, stent, vascular implant or other type of implant. The endoluminal device can have circumferential member with an undulating configuration having multiple inward and outward apexes and struts extending therebetween. Two of the struts can be used to establish a foot for the precise positioning of the device during deployment. A method of placing the endoluminal device can include withdrawing an outer sheath such that a portion of the endoluminal device is expanded prior to the rest of the endoluminal device.
摘要翻译：腔内装置可以配置成在容器内部署期间进行精确定位。腔内装置可以是粘性，支架，血管植入物或其它类型的植入物。腔内装置可以具有带有多个向内和向外顶点的起伏构型的圆周构件和在它们之间延伸的支柱。两个支柱可用于在部署期间为设备的精确定位建立脚。放置腔内装置的方法可以包括抽出外护套，使得在腔内装置的其余部分之前使腔内装置的一部分膨胀。

10. 发明申请

WO2013043703A1 HARVESTING FAT TISSUE USING TISSUE LIQUEFACTION 审中-公开
标题翻译：使用组织液化收集脂肪组织
公开(公告)号：WO2013043703A1
公开(公告)日：2013-03-28
申请号：PCT/US2012/056088
申请日：2012-09-19
申请人： ANDREW TECHNOLOGIES LLC
发明人： ANDREW, Mark, S. , CHAN, Phillip, P. , GODEK, Christopher, P.
IPC分类号： A61B17/3203 , A61B17/32 , A61K35/12
CPC分类号： A61K35/35 , A61B17/320016 , A61B17/3203 , A61B17/32037 , A61B2017/00274 , A61B2017/00792 , A61B2017/00796 , A61B2017/00969 , A61B2017/22079 , A61B2017/22081 , A61B2018/00035 , A61B2018/00339 , A61B2217/005 , A61M1/0064 , A61M1/008 , A61M2202/0014 , A61M2202/08
摘要： Target tissue may be removed from a subject using a cannula (30) that has an interior cavity and an orifice (37) configured to permit material to enter the cavity. This is accomplished by generating a negative pressure in the cavity so that a portion of the tissue is drawn into the orifice. Fluid is then delivered, via a conduit (35), so that the fluid exits the conduit within the cavity and impinges against the portion of the tissue that was drawn into the orifice. The fluid is delivered at a pressure and temperature that causes the tissue to soften, liquefy, or gellify. The tissue that has been softened, liquefied, or gel I if ied is then suctioned away. The matter that was suctioned away is collected and gravity separated, and fat that is suitable for implantation in the subject is extracted from a selected layer (e.g., the top half) of the supernatant of the gravity-separated matter.
摘要翻译：可以使用具有内腔的插管（30）和构造成允许材料进入空腔的孔口（37）从对象中移除靶组织。这通过在空腔中产生负压使得组织的一部分被吸入孔中来实现。然后通过导管（35）输送流体，使得流体离开空腔内的导管并撞击被吸入孔中的组织部分。在压力和温度下输送流体，导致组织软化，液化或凝胶化。然后将已经软化，液化或凝胶化的组织吸出。被抽出的物质被收集并重力分离，并且适于植入受试者的脂肪从重力分离物质的上清液的选定层（例如，上半部分）中提取。

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