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1. 发明申请

WO2018194980A1 LITHOTRIPSY ANGIOPLASTY DEVICES AND METHODS 审中-公开
公开(公告)号：WO2018194980A1
公开(公告)日：2018-10-25
申请号：PCT/US2018/027801
申请日：2018-04-16
申请人： BOSTON SCIENTIFIC SCIMED, INC.
发明人： EGGERT, Joel T. , PAGORIA, Douglas Dean , GESSLER, Raymond , PENNINGTON, Douglas , FOSTER, Daniel J. , ROHL, James P.
IPC分类号： A61B17/22
CPC分类号： A61B17/22012 , A61B17/22004 , A61B2017/00553 , A61B2017/22008 , A61B2017/22014 , A61B2017/22015 , A61B2017/22025 , A61B2017/22051 , A61B2017/22061 , A61B2017/22062 , A61M25/1018 , A61M25/104
摘要： Medical devices and method for making and using medical devices are disclosed. An example method for treating a blood vessel may include disposing a medical device within the blood vessel at a position adjacent to a lesion. The medical device may include an elongate shaft having a distal end region, a balloon coupled to the distal end region, and a cavitation member disposed within the balloon. The method may also include inflating the balloon to a first pressure, activating the cavitation member, and inflating the balloon to a second pressure greater than the first pressure.

2. 发明申请

WO2017147493A1 ENHANCED FLEXIBILITY NEUROVASCULAR CATHETER 审中-公开
标题翻译：增强的灵活性神经血管导管
公开(公告)号：WO2017147493A1
公开(公告)日：2017-08-31
申请号：PCT/US2017/019453
申请日：2017-02-24
申请人： INCEPT, LLC
发明人： YANG, Yi , KHOSRAVI, Fred , RIMSA, Joseph
IPC分类号： A61B17/00 , A61M25/00 , A61M25/01 , A61M29/00
CPC分类号： A61M25/0053 , A61B6/481 , A61B17/12022 , A61B17/12168 , A61B17/12186 , A61B17/22 , A61B17/22012 , A61B17/2202 , A61B17/22031 , A61B17/3203 , A61B17/32037 , A61B17/320758 , A61B2017/00398 , A61B2017/00526 , A61B2017/00734 , A61B2017/00862 , A61B2017/00867 , A61B2017/00898 , A61B2017/00955 , A61B2017/22025 , A61B2017/22034 , A61B2017/22038 , A61B2017/22062 , A61B2017/22067 , A61B2017/22079 , A61B2017/22084 , A61B2017/320733 , A61B2017/320775 , A61B2217/005 , A61F2/95 , A61F7/12 , A61F2007/126 , A61L29/02 , A61L29/041 , A61L29/06 , A61L29/14 , A61L2400/10 , A61L2400/16 , A61M1/0035 , A61M1/0066 , A61M1/008 , A61M1/32 , A61M5/007 , A61M25/0009 , A61M25/0012 , A61M25/0023 , A61M25/0045 , A61M25/005 , A61M25/007 , A61M25/0074 , A61M25/01 , A61M25/0102 , A61M25/0108 , A61M25/0147 , A61M25/0662 , A61M25/09 , A61M25/10 , A61M25/1027 , A61M39/06 , A61M2025/0046 , A61M2025/0059 , A61M2025/0175 , A61M2039/062 , A61M2205/0216 , A61M2205/0266 , A61M2205/3344 , A61M2210/12 , B29C41/14 , B29K2027/18 , B29K2075/00 , B29L2031/7542
摘要： A catheter is provided, such as for distal neurovascular access or aspiration. The catheter includes an elongate flexible body, having a proximal end, a distal end and a side wall defining a central lumen. A distal zone of the side wall includes a tubular inner liner, a tie layer separated from the lumen by the inner liner, a helical coil surrounding the tie layer, adjacent windings of the coil spaced progressively further apart in the distal direction. An outer jacket surrounds the helical coil. The outer jacket is formed from a plurality of tubular segments positioned end to end, coaxially about the coil. The flexural load profile of the catheter as a function of catheter length is configured to provide enhanced distal flexibility while maintaining high backup support.
摘要翻译：提供导管，例如用于远端神经血管通路或抽吸。导管包括细长柔性主体，其具有限定中央内腔的近端，远端和侧壁。侧壁的远侧区域包括管状内衬，通过内衬与内腔隔开的连接层，围绕连接层的螺旋线圈，线圈的相邻绕圈在远侧方向上逐渐进一步间隔开。外套围绕螺旋线圈。外护套由多个管状部分形成，首尾相连，同轴环绕线圈。导管的弯曲载荷曲线作为导管长度的函数被配置为提供增强的远端柔性，同时保持高度的后备支撑。

3. 发明申请

WO2016089683A1 ELECTRO-HYDRAULICALLY ACTUATED LITHOTRIPTERS AND RELATED METHODS 审中-公开
标题翻译：电液压驱动器和相关方法
公开(公告)号：WO2016089683A1
公开(公告)日：2016-06-09
申请号：PCT/US2015/062476
申请日：2015-11-24
申请人： C.R. BARD, INC.
发明人： DOLGIN, Michael
IPC分类号： A61B17/00 , A61B17/22 , A61B17/32
CPC分类号： A61B17/22012 , A61B17/2202 , A61B2017/22021 , A61B2017/22025
摘要： Embodiments are directed to electro-hydraulically actuated lithotripters and methods for fragmenting stones using such lithotripters. In an embodiment, a lithotripter apparatus for fragmenting at least one stone in a body is disclosed. The lithotripter apparatus includes a chamber configured to contain an electro-conductive fluid, which includes a proximal end wall and a distal end wall spaced from the proximal end wall. A chisel is coupled to the chamber and located at least proximate to the distal end wall. A proximal electrode is located at least partially in the chamber. A distal electrode is located at least partially in the chamber and spaced from the proximal electrode. Responsive to an effective voltage applied between the proximal and distal electrodes, the proximal and distal electrodes are configured to electrically discharge into the electro-conductive fluid to generate shock waves in the chamber that accelerate the chisel toward the at least one stone.
摘要翻译：实施例涉及电液压驱动的碎石机和使用这种碎石机碎石的方法。在一个实施例中，公开了一种用于碎片体内的至少一块石块的碎石机装置。碎石机装置包括被配置为容纳导电流体的腔室，该导电流体包括近端壁和与近端壁间隔开的远端壁。凿子联接到腔室并且至少靠近远端壁定位。近端电极至少部分地位于腔室中。远端电极至少部分地位于腔室中并与近端电极间隔开。响应于施加在近端和远端电极之间的有效电压，近端电极和远端电极被配置为电放电到导电流体中，以在腔室中产生冲击波，从而将凿子朝向至少一块石头加速。

4. 发明申请

WO2014140715A3 UNFOCUSED ELECTROHYDRAULIC LITHOTRIPTER 审中-公开
标题翻译：无相关电化学提取仪
公开(公告)号：WO2014140715A3
公开(公告)日：2015-12-03
申请号：PCT/IB2014000275
申请日：2014-03-10
申请人： NORTHGATE TECHNOLOGIES INC
发明人： MANTELL ROBERT
IPC分类号： A61B17/22
CPC分类号： A61B17/22022 , A61B2017/22025 , A61B2017/22028
摘要： Electrohydraulic lithotripters comprising a plurality of electrohydraulic probes are disclosed. Each probe of the plurality of probes comprise a first electrode and a second electrode positioned at a distal end of the probe such that when the probe is discharged, an electric arc between the first electrode and the second electrode produces a Shockwave that radiates from the distal end of the probe. A first probe and a second probe of the plurality of probes may be configured to discharge simultaneously or sequentially.
摘要翻译：公开了包括多个电液探头的电液碎石机。多个探针的每个探针包括位于探针的远端处的第一电极和第二电极，使得当探针被放电时，第一电极和第二电极之间的电弧产生从远端辐射的冲击波探头末端。多个探针的第一探针和第二探针可以被配置为同时或顺序地放电。

5. 发明申请

WO2012106259A3 HIGH PRESSURE BALLOON SHOCKWAVE CATHETER AND METHOD 审中-公开
标题翻译：高压气球冲击导管及方法
公开(公告)号：WO2012106259A3
公开(公告)日：2013-01-31
申请号：PCT/US2012023172
申请日：2012-01-30
申请人： HAWKINS DANIEL , ADAMS JOHN , GOFF THOMAS
发明人： HAWKINS DANIEL , ADAMS JOHN , GOFF THOMAS
IPC分类号： A61F2/958 , A61M25/10 , A61B18/24 , A61B18/26
CPC分类号： A61B17/2202 , A61B17/22022 , A61B2017/22025 , A61B2017/22062 , A61B2017/22065
摘要： A system and method for breaking obstructions in body lumens includes a catheter including an elongated carrier, a balloon at one end of the carrier in sealed relation thereto, the carrier including a channel arranged to receive a fluid that fills and pressurizes the balloon to an internal pressure of greater than two atmospheres, and an arc generator including at least one electrode within the balloon that forms a mechanical shock wave within the balloon. The system further includes a power source that provides electrical energy to the arc generator.
摘要翻译：用于破坏体腔内的障碍物的系统和方法包括导管，其包括细长的载体，与所述载体的密封关系的一端处的气囊，所述载体包括通道，所述通道被布置成接收将气囊填充并加压到内部大于2个大气压的压力，以及包括球囊内的至少一个电极的电弧发生器，其在球囊内形成机械冲击波。该系统还包括向电弧发生器提供电能的电源。

6. 发明申请

WO2009052393A1 A DEVICE FOR TRANSFECTING CELLS USING SHOCK WAVES GENERATED BY THE IGNITION OF NANOENERGETIC MATERIALS 审中-公开
标题翻译：使用由纳米材料点火产生的震动波转移细胞的装置
公开(公告)号：WO2009052393A1
公开(公告)日：2009-04-23
申请号：PCT/US2008/080332
申请日：2008-10-17
申请人： CURATORS OF THE UNIVERSITY OF MISSOURI , APPERSON, Steve , GANGOPADHYAY, Shubhra , POLO-PARADA, Luis , BEZMELNITSYN, Andrey , GANGOPADHYAY, Keshab
发明人： APPERSON, Steve , GANGOPADHYAY, Shubhra , POLO-PARADA, Luis , BEZMELNITSYN, Andrey , GANGOPADHYAY, Keshab
IPC分类号： C06B33/00
CPC分类号： A61B17/2202 , A61B17/22004 , A61B2017/22025
摘要： A miniature device for generating shock waves using the energy of combustion of a nanoenergetic material and directing the shock waves into biological tissues is described.
摘要翻译：描述了使用纳米能量材料的燃烧能量并将冲击波引导到生物组织中产生冲击波的微型装置。

7. 发明申请

WO2018026700A1 DEVICE FOR IMPROVING ELECTROHYDRAULIC LITHOTRIPSY PROBE STIFFNESS 审中-公开
标题翻译：用于改善电磁液压探测器刚度的装置
公开(公告)号：WO2018026700A1
公开(公告)日：2018-02-08
申请号：PCT/US2017/044645
申请日：2017-07-31
申请人： COOK MEDICAL TECHNOLOGIES LLC
发明人： WILLIAMS, Michael, Lee , KENNEDY, Kenneth, C. II
IPC分类号： A61B17/22
CPC分类号： A61B17/22012 , A61B17/00234 , A61B17/2202 , A61B2017/0034 , A61B2017/22021 , A61B2017/22025 , A61M25/0053 , A61M25/0102
摘要： A lithotripsy probe (10) is provided including an elongate body with a proximal end, a distal end, and a lumen extending therethrough. The lithotripsy probe (10) further includes a stiffening element (46) with a proximal end, a distal end, and a length extending from the proximal end to the distal end. The stiffening element (46) is disposed within the lumen of the elongate body. The stiffening element (46) has a stiffness that varies along the length of the stiffening element, where the stiffness of the proximal end of the stiffening element is greater than the stiffness of the distal end of the stiffening element.
摘要翻译：提供了一种碎石探针（10），其包括具有近端，远端和延伸穿过其中的内腔的细长本体。碎石探测器（10）还包括具有近端，远端和从近端延伸到远端的长度的加强元件（46）。加强元件（46）设置在细长主体的内腔内。加强元件（46）具有沿着加强元件的长度变化的刚度，其中加强元件的近端的刚度大于加强元件的远端的刚度。

8. 发明申请

WO2016109737A1 ELECTRICALLY-INDUCED FLUID FILLED BALLOON CATHETER 审中-公开
标题翻译：电动感应流体填充气泡导管
公开(公告)号：WO2016109737A1
公开(公告)日：2016-07-07
申请号：PCT/US2015/068170
申请日：2015-12-30
申请人： THE SPECTRANETICS CORPORATION
发明人： GRACE, Kenneth, P. , TRIFFO, Thomas , CEZO, James
IPC分类号： A61M25/10 , A61M25/00
CPC分类号： A61M25/104 , A61B17/22022 , A61B2017/22007 , A61B2017/22021 , A61B2017/22024 , A61B2017/22025 , A61B2017/22051 , A61M37/0092 , A61M2025/105 , A61M2025/1075 , A61M2025/1081 , A61M2025/1093 , A61M2205/054
摘要： The present disclosure relates generally to the use of medical devices for the treatment of vascular conditions. In particular, the present disclosure provides devices and methods for using electrically-induced pressure waves to disrupt vascular blockages. The present disclosure not only provides devices and methods for using electrically-induced pressure waves to disrupt vascular blockages, but the present disclosure also provides devices and method for assisting the guidewire in penetrating an occlusion, devices and method for using a sealable valve in the tip of the balloon catheter to reduce the overall size and diameter of the balloon catheter, thereby allowing the balloon catheter to penetrate smaller size blood vessels and devices. Given the persistence of coronary artery disease (CAD) and peripheral artery disease (PAD), there remains a need for improved therapeutic methods designed not only to reduce vascular blockages in the short term, but also to prevent future complications such as restenosis.
摘要翻译：本公开一般涉及医疗装置用于治疗血管病症的用途。特别地，本公开提供了使用电感应压力波来破坏血管阻塞的装置和方法。本公开不仅提供了使用电诱导的压力波来破坏血管阻塞的装置和方法，而且本公开还提供了用于辅助导丝穿透闭塞的装置和方法，用于在尖端中使用可密封的阀的装置和方法以减小气囊导管的总体尺寸和直径，从而允许气囊导管穿透较小尺寸的血管和装置。鉴于冠状动脉疾病（CAD）和外周动脉疾病（PAD）的持续存在，仍然需要改进的治疗方法，不仅在短期内设计减少血管阻塞，而且还防止未来并发症如再狭窄。

9. 发明申请

WO2014027240A2 ELECTROHYDRAULIC LITHOTRIPSY PROBE AND ELECTRICAL SOURCE FOR AN ELECTROHYDRAULIC LITHOTRIPSY PROBE 审中-公开
标题翻译：电驱动探测器的电液驱动探测器和电源
公开(公告)号：WO2014027240A2
公开(公告)日：2014-02-20
申请号：PCT/IB2013/001784
申请日：2013-08-15
申请人： NORTHGATE TECHNOLOGIES INC.
发明人： MANTELL, Robert , CURTIS, Chip , SOBELEVSKY, Mikhail
IPC分类号： A61B17/22
CPC分类号： A61B17/22022 , A61B2017/00154 , A61B2017/22025 , A61B2017/22062 , A61B2017/22098 , H01T2/00 , H01T14/00 , H01T15/00 , H03K3/537
摘要： A lithotripter probe system including an invasive lithotripter tip and an electrical source for the lithotripter tip are disclosed. The lithotripter tip includes a first and second electrode positioned on the lithotripter tip such that an electric arc between the ends of the first and second electrodes causes a Shockwave to radiate from the lithotripter tip. The electric source includes a first spark gap, a second park gap electrically connected in series with the first spark gap, and a storage capacitor electrically connected in parallel with the first and second spark gaps. The first electrode is electrically connected to the storage capacitor via the serially connected first and second spark gaps, and when the first and second spark gaps conduct, the storage capacitor is configured to discharge to the first electrode, thereby causing the electric arc between the ends of the first and second electrodes.
摘要翻译：公开了包括侵入式碎石器尖端和用于碎石器尖端的电源的碎石探测器系统。碎石器尖端包括定位在碎石器尖端上的第一和第二电极，使得第一和第二电极的端部之间的电弧引起冲击波从碎石器尖端辐射。电源包括第一火花间隙，与第一火花间隙串联电连接的第二停车间隙以及与第一火花间隙和第二火花间隙并联电连接的存储电容器。第一电极经由串联连接的第一火花隙和第二火花隙而电连接至存储电容器，并且当第一火花隙和第二火花隙导电时，存储电容器被配置为向第一电极放电，由此引起端部之间的电弧的第一和第二电极。

10. 发明申请

WO2012053267A1 光ファイバーおよびそれを用いた水中衝撃波発生装置审中-公开
标题翻译：光纤和水下冲击产生使用该设备的设备
公开(公告)号：WO2012053267A1
公开(公告)日：2012-04-26
申请号：PCT/JP2011/067140
申请日：2011-07-27
申请人：国立大学法人東北大学 , 高山和喜 , 山本裕朗 , 下川宏明
发明人：高山　和喜 , 山本　裕朗 , 下川　宏明
IPC分类号： A61B17/00 , A61B17/22 , A61B18/20
CPC分类号： A61B18/22 , A61B17/22012 , A61B18/26 , A61B2017/22024 , A61B2017/22025 , A61B2018/263 , G02B6/262
摘要：レーザー光の集光効率が良く、耐久性の高い光ファイバーおよびそれを用いた衝撃波発生装置を提供する。水中にレーザー光を照射して水中衝撃波を発生させる水中衝撃波発生装置１０に用いられる光ファイバー１１。光ファイバー１１は、本体部１６と、その先端に設けられたレーザー収束部１７とからなり、レーザー収束部１７が先端１８ａの径が基端１８ｂの径より小さい略円錐台の形状を呈しており、かつ、軸線断面の側辺の半径方向に対する内角θが、先に向かって徐々に小さくなるように構成されている。
摘要翻译：提供了具有良好的激光束冷凝效率和高弹性的光纤，以及采用该光纤的冲击波产生装置。在水下冲击波发生装置（10）中使用光纤（11），其在水下投影激光束并产生水下冲击波。光纤（11）包括：主体部分（16）; 以及设置在其前端的激光会聚部（17）。激光会聚部（17）构成为具有近似截头圆锥形状，其中前端（18a）的直径比基端（18b）的直径窄，并且使得内角θ 相对于轴向截面的侧面的径向方向朝向其前方逐渐减小。

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