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    • 10. 发明申请
    • HEART VALVE PROSTHESIS AND METHOD
    • 心脏瓣膜假体和方法
    • WO2010057262A1
    • 2010-05-27
    • PCT/AU2009/001513
    • 2009-11-20
    • PERCUTANEOUS CARDIOVASCULAR SOLUTIONS PTY LIMITEDTHAMBAR, SukuCOOK, Martin, ChristopherSCHRECK, StefanJAYASINGHE, Stayajit, Rohan
    • THAMBAR, SukuCOOK, Martin, ChristopherSCHRECK, StefanJAYASINGHE, Stayajit, Rohan
    • A61F2/00
    • A61B17/0057A61B2017/00575A61B2017/0061A61F2/2418A61F2/2436A61F2/2457A61F2002/8486A61F2220/0008A61F2220/0016A61F2230/0054A61F2230/0078A61F2230/008A61F2250/006
    • A heart valve prosthesis (100) comprises a housing component (110) and a valve component (130). The housing component (110) comprises a housing body (111) having a housing passage (112) extending therethrough. The housing body (111) is configured to be located in, or adjacent to and communicating with, a native valve orifice (16) of a heart (10) and to engage structure of the heart (10) to fix the housing body (111) in relation to the valve orifice (161). The housing component (111) is collapsible for delivery via catheter (2). The valve component (130) comprises a valve body (131) having a valve passage (132) extending therethrough. The valve body (131) is configured to be fixed within the housing passage (112) with the valve passage (132) extending along the housing passage (112). One or more flexible valve elements (131) is/are secured to the valve body and extend across the valve passage (132) for blocking blood flow in a first direction through the valve passage (132) whilst allowing blood flow in the opposing direction. The valve component (130) is collapsible for delivery via catheter (2) separate to the housing component (110). An associated method of replacing a failed or failing heart valve utilising the heart valve prosthesis (100) is also disclosed.
    • 心脏瓣膜假体(100)包括壳体部件(110)和阀部件(130)。 壳体部件(110)包括具有延伸穿过其中的壳体通道(112)的壳体(111)。 壳体(111)构造成位于心脏(10)的天然瓣膜(16)中或邻近并连通,并与心脏(10)的结构接合以固定壳体(111) )相对于阀孔(161)。 壳体部件(111)可折叠以便经由导管(2)输送。 阀部件(130)包括具有延伸穿过其中的阀通道(132)的阀体(131)。 阀体(131)构造成固定在壳体通道(112)内,阀通道(132)沿壳体通道(112)延伸。 一个或多个柔性阀元件(131)被固定到阀体并延伸穿过阀通道(132),用于阻止通过阀通道(132)的第一方向的血液流动,同时允许血液沿相反方向流动。 阀部件(130)可折叠以便通过分离到壳体部件(110)的导管(2)输送。 还公开了利用心脏瓣膜假体(100)代替故障或故障心脏瓣膜的相关方法。