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1. 发明申请

WO2005032415A3 REMOVABLE BILIARY STENT 审中-公开
标题翻译：可拆卸双子座
公开(公告)号：WO2005032415A3
公开(公告)日：2007-05-31
申请号：PCT/US2004031906
申请日：2004-09-29
申请人： ALVEOLUS INC , MANGIARDI ERIC , REYNOLDS JASON , BORG ULF , ALEXANDER TONY
发明人： MANGIARDI ERIC , REYNOLDS JASON , BORG ULF , ALEXANDER TONY
IPC分类号： A61M29/00 , A61F20060101 , A61F2/00 , A61F2/06 , A61L31/08
CPC分类号： A61L31/08 , A61F2/07 , A61F2/91 , A61F2/915 , A61F2002/041 , A61F2002/065 , A61F2002/91525 , A61F2002/91533 , A61F2002/91566 , A61F2002/91575 , A61F2230/0013 , A61F2230/0017 , A61F2250/0018 , A61F2250/0039 , A61F2250/0051
摘要： The present invention, in an exemplary embodiment, provides a stent, which combines many of the excellent characteristics of both silicone and metal stents while eliminating the undesirable ones. In particular, a principal objective in accordance with the present invention is to provide a family of stents generally and a biliary stent in particular where the relative hardness/softness of regions of the stent can differ from other regions of the stent to provide additional patient comfort and resistance to radial forces. An exemplary embodiment also provides a family of stents with novel interstice configurations that facilitate flexibility, durability and/or proper installation. Additionally, the biliary stent in accordance with the present invention provides enhanced flow mechanics to ensure the adequate clearance of viscid fluids such as bile.
摘要翻译：本发明在一个示例性实施例中提供一种支架，其结合了硅树脂和金属支架的许多优异特性，同时消除了不期望的支架。特别地，根据本发明的主要目的是提供一般的支架系列和胆管支架，特别是其中支架区域的相对硬度/柔软度可以与支架的其它区域不同以提供额外的患者舒适度和抗径向力。示例性实施例还提供了具有新颖空隙配置的支架系列，其有助于灵活性，耐久性和/或适当的安装。此外，根据本发明的胆管支架提供增强的流动力学以确保粘性流体如胆汁的足够的间隙。

2. 发明申请

WO2005025448A3 WOUND HEALING APPARATUS WITH BIOABSORBABLE MATERIAL AND SUCTION TUBES 审中-公开
标题翻译：具有生物可吸收材料和吸管的创伤治疗装置
公开(公告)号：WO2005025448A3
公开(公告)日：2007-04-12
申请号：PCT/US2004029309
申请日：2004-09-09
申请人： SPHERIC PARTNERS LTD , WATSON RICHARD L JR
发明人： WATSON RICHARD L JR
IPC分类号： A61F13/00 , A61F20060101 , A61F2/00 , A61M27/00 , A61M35/00
CPC分类号： A61M27/00
摘要： An apparatus for placement in a wound to promote healing, and a method of treating wounds using such apparatus. The apparatus comprises a bioabsorbable fabric supported by a skeleton of impervious flexible members, such as Teflon TM tubes. When placed inside the wound, the bioabsorbable fabric absorbs into the body within about 5 to 10 days. As the fabric is being absorbed, it serves as a framework for fibroblasts to bridge the gap in the wounded tissue and thereby promote healing. The tubes serve as conduits to remove excess fluids from the wound, preferably under the power of a suction device to which the tubes are connected outside the body. After the fabric is absorbed by the body, the flexible tubes are removed. An expandable embodiment may be deployed into a wound cavity via an introducer tube and plunger. The apparatus may incorporate various sensors.
摘要翻译：用于放置在伤口中以促进愈合的装置，以及使用这种装置治疗伤口的方法。该装置包括由诸如Teflon TM管之类的不透水柔性构件骨架支撑的生物可吸收织物。当放置在伤口内时，生物可吸收织物在约5至10天内吸收进入体内。当织物被吸收时，其用作成纤维细胞桥接伤口组织间隙并从而促进愈合的框架。管用作导管以从伤口除去多余的流体，优选地在吸管装置的功率下，管连接到身体外部。在织物被身体吸收之后，去除柔性管。可扩展的实施例可以经由导引管和柱塞部署到伤口腔中。该装置可以结合各种传感器。

3. 发明申请

WO2004045451A9 APPARATUS AND METHOD FOR MAINTAINING BONES IN A HEALING POSITION 审中-公开
标题翻译：用于维持治疗位置的骨骼的装置和方法
公开(公告)号：WO2004045451A9
公开(公告)日：2007-02-22
申请号：PCT/US0336386
申请日：2003-11-13
申请人： AMEI TECHNOLOGIES INC
发明人： RUCH DAVID S , BRYANT RICHARD M
IPC分类号： A61B17/56 , A61B17/60 , A61B17/64 , A61F20060101
CPC分类号： A61B17/60 , A61B17/6425 , A61B17/6458 , A61B2017/603
摘要： An apparatus (40) is provided to reduce bony fragments and maintain a human's wrist or hand in a healing position. The apparatus (40) may include a first clamp assembly (50) operable to removably mount to an external fixator (20) when the external fixator is coupled to a first bone of a human. A second clamp assembly may be releasably engaged with at least one bone pin (66) embedded in a second bone of a human. A connector rod (42) may be provided to join the first clamp assembly (50) to the second clamp assembly (60).
摘要翻译：提供了一种装置（40），用于减少骨碎片并将人的手腕或手保持在愈合位置。当外部固定器联接到人的第一骨骼时，装置（40）可以包括可操作以可移除地安装到外部固定器（20）的第一夹具组件（50）。第二夹具组件可以与嵌入在人的第二骨中的至少一个骨销（66）可释放地接合。可以设置连接杆（42）以将第一夹具组件（50）连接到第二夹具组件（60）。

4. 发明申请

WO2005011522A3 PROSTHETIC SPINAL DISC REPLACEMENT 审中-公开
标题翻译：前列腺椎间盘置换术
公开(公告)号：WO2005011522A3
公开(公告)日：2007-01-25
申请号：PCT/US2004024933
申请日：2004-07-30
申请人： GLOBUS MEDICAL INC , PAUL DAVID C , ANGELUCCI CHRISTOPHER M , BOYER MICHAEL L II
发明人： PAUL DAVID C , ANGELUCCI CHRISTOPHER M , BOYER MICHAEL L II
IPC分类号： A61B17/56 , A61B17/00 , A61B17/02 , A61B17/16 , A61B17/17 , A61B17/90 , A61F20060101 , A61F2/00 , A61F2/02 , A61F2/30 , A61F2/44
CPC分类号： A61F2/442 , A61B17/1604 , A61B17/1671 , A61B17/1735 , A61B17/1757 , A61B2017/0046 , A61B2017/0256 , A61F2/4425 , A61F2002/30014 , A61F2002/30113 , A61F2002/30125 , A61F2002/30166 , A61F2002/302 , A61F2002/30224 , A61F2002/30365 , A61F2002/30471 , A61F2002/30545 , A61F2002/30563 , A61F2002/30568 , A61F2002/30571 , A61F2002/30579 , A61F2002/30594 , A61F2002/30604 , A61F2002/30649 , A61F2002/30662 , A61F2002/30769 , A61F2002/30772 , A61F2002/30878 , A61F2002/30884 , A61F2002/443 , A61F2002/448 , A61F2220/0033 , A61F2220/0091 , A61F2230/0006 , A61F2230/0008 , A61F2230/0028 , A61F2230/0065 , A61F2230/0069 , A61F2230/0071 , A61F2250/001 , A61F2250/0018 , A61F2310/00407 , A61F2310/00796
摘要： The present invention relates generally to a prosthetic spinal disc for replacing a damaged disc between two vertebrae of a spine. The present invention also relates to a method for implanting a prosthetic spinal disc via posterior or posterior lateral implantation. Other surgical approaches for implanting the prosthetic disc may also be used. The present invention also involves a method for implanting the prosthetic spinal disc while either avoiding or minimizing contact with the spinal cord and nerve rootlets, or reducing the time and extent that they need to be repositioned during implantation.
摘要翻译：本发明一般涉及用于替换椎骨的两个椎骨之间的受损椎间盘的假脊椎盘。本发明还涉及通过后侧或后侧植入植入假肢脊椎盘的方法。也可以使用用于植入假体盘的其它手术方法。本发明还涉及一种用于植入假肢脊椎盘的方法，同时避免或最小化与脊髓和神经根的接触，或减少在植入期间需要重新定位的时间和程度。

5. 发明申请

WO2004110308A3 OSTEOIMPLANTS AND METHODS FOR THEIR MANUFACTURE 审中-公开
标题翻译： OSTEOIMPLANTS及其制造方法
公开(公告)号：WO2004110308A3
公开(公告)日：2006-10-26
申请号：PCT/US2004018618
申请日：2004-06-10
申请人： OSTEOTECH INC , BUREL MARC HENRY , CLARK CHRIS H , FORSYTH NANETTE , MORRIS JOHN W , QUACKENBUSH DAVID F , TRAIANEDES KATHY , WATSON KIMBERLY D , YONCAK RICHARD ANTHONY
发明人： BUREL MARC HENRY , CLARK CHRIS H , FORSYTH NANETTE , MORRIS JOHN W , QUACKENBUSH DAVID F , TRAIANEDES KATHY , WATSON KIMBERLY D , YONCAK RICHARD ANTHONY
IPC分类号： A61F2/28 , A61F20060101 , A61F2/00 , A61F2/30 , A61F2/44 , A61F2/46
CPC分类号： A61F2/28 , A61F2/4455 , A61F2/4644 , A61F2002/2817 , A61F2002/2835 , A61F2002/30059 , A61F2002/30075 , A61F2002/30153 , A61F2002/30329 , A61F2002/30593 , A61F2002/30677 , A61F2002/30805 , A61F2002/30957 , A61F2002/30975 , A61F2002/4649 , A61F2210/0061 , A61F2220/0025 , A61F2230/0019 , A61F2310/00293 , A61F2310/00329 , A61F2310/00365 , A61L27/3608 , A61L27/365 , A61L27/3658 , A61L27/38 , A61L31/005 , A61L2430/02
摘要： An osteoimplant is made up of a coherent aggregate of elongate bone particles.
摘要翻译：骨植入物由细长骨颗粒的粘附聚集体组成。

6. 发明申请

WO2005058193A3 NON-SURGICALLY CORRECTING ABNORMAL KNEE LOADING 审中-公开
标题翻译：非正常矫正异常卡尼装载
公开(公告)号：WO2005058193A3
公开(公告)日：2006-09-14
申请号：PCT/US2004041304
申请日：2004-12-10
申请人： UNIV COLORADO , GAMADA KAZUYOSHI
发明人： GAMADA KAZUYOSHI
IPC分类号： A61F20060101 , A61F5/00
CPC分类号： A61F5/0123 , A61F2005/0146
摘要： The invention provides hinges (2) for use in knee braces to correct and prevent knee pathology. Further provided are knee braces comprising the hinges of the present invention to correct and prevent knee pathology including osteoarthritis. Also provided are methods of treating knee pathology by using the hinges and braces of the present invention to apply a corrective rotational force and an off-loading force to the affected knee compartment.
摘要翻译：本发明提供了用于膝关节支架的铰链（2），用于矫正和预防膝关节病理学。还提供了包括本发明的铰链的膝盖支架，用于矫正和预防包括骨关节炎的膝盖病变。还提供了通过使用本发明的铰链和支架来治疗膝关节病理学的方法，以向受影响的膝盖室施加矫正旋转力和卸载力。

7. 发明申请

WO2004073765A3 DRUG DELIVERY DEVICE AND SYRINGE FOR FILLING THE SAME 审中-公开
标题翻译：药液递送装置和灌装装置
公开(公告)号：WO2004073765A3
公开(公告)日：2006-07-20
申请号：PCT/US2004004643
申请日：2004-02-18
申请人： EYETECH PHARMACEUTICALS INC , BREEGI WISAM , CALIAS PERICLES , ADAMIS ANTHONY P , SHIMA DAVID , CUNNINGHAM EMEMETT T
发明人： BREEGI WISAM , CALIAS PERICLES , ADAMIS ANTHONY P , SHIMA DAVID , CUNNINGHAM EMEMETT T
IPC分类号： A61F9/00 , A61F20060101 , A61K9/22 , A61M20060101 , A61M5/178
CPC分类号： A61F9/0017
摘要： The invention relates to the field of drug delivery devices. More particularly, the invention relates to implantable, refillable drug delivery devices which provide for drug delivery over sustained time periods. The present invention has particular application for ophthalmic drug delivery applications.
摘要翻译：本发明涉及药物输送装置领域。更具体地说，本发明涉及可持续的时间段提供药物输送的可植入的可重新填充的药物递送装置。本发明特别适用于眼药物递送应用。

8. 发明申请

WO2005048875A3 DELIVERY DEVICE AND METHOD OF DELIVERY 审中-公开
标题翻译：交付设备和交付方法
公开(公告)号：WO2005048875A3
公开(公告)日：2006-06-29
申请号：PCT/US2004038345
申请日：2004-11-15
申请人： MEDICAL INSTILL TECH INC , PY DANIEL C , CHAN JULIAN V , ATWOOD JEFFREY M
发明人： PY DANIEL , CHAN JULIAN V , ATWOOD JEFFREY M
IPC分类号： A61F20060101 , A61F9/00 , A61M35/00
CPC分类号： B05B11/007 , A61F9/0008 , A61M11/007 , A61M15/08 , A61M35/003 , A61M2210/0612 , B05B11/0043 , B05B11/0048 , B05B11/0056 , B05B11/0072 , B05B11/3004 , B05B11/3056 , B05B11/307 , B05B11/3074 , B05B11/3077
摘要： An ophthalmic delivery device includes a body defining a fluid reservoir and a pump in fluid communication with the reservoir. The delivery device also includes a nozzle that includes a dosage chamber for holding a dosage of fluid, a valve seat, and a valve cover. The valve cover extends about the valve seat and forms an interface therebetween and the valve seat includes an outlet aperture. The interface is in fluid communication with the outlet aperture and the dosage chamber, and at least part of the valve cover is movable between (i) a closed position with the valve cover engaging the valve seat to close the interface and form a fluid-tight seal therebetween, and (ii) an open position with at least part of the valve cover spaced away from the valve seat in response to fluid flowing through the outlet aperture at a pressure greater than a valve opening pressure to allow the passage of pressurized fluid therebetween. The valve seat and the valve cover are dimensioned to dispense the dosage of fluid through the interface at a velocity of equal to or less than 6 meters per second.
摘要翻译：眼科输送装置包括限定流体储存器的主体和与储存器流体连通的泵。输送装置还包括喷嘴，该喷嘴包括用于保持一定量的流体的剂量室，阀座和阀盖。阀盖围绕阀座延伸并且在它们之间形成界面，并且阀座包括出口孔。所述界面与所述出口孔和所述剂量室流体连通，并且所述阀盖的至少一部分可在（i）与所述阀盖接合所述阀座的关闭位置之间移动以关闭所述界面并形成流体密封密封在其间，和（ii）打开位置，其中阀盖的至少一部分响应于流体以大于阀打开压力的压力流过出口孔而与阀座间隔开，以允许加压流体在其间通过。阀座和阀盖的尺寸设计为以等于或小于6米/秒的速度通过界面分配流体的剂量。

9. 发明申请

WO2006040760A2 HERNIA REPAIR DEVICE 审中-公开
标题翻译： HERNIA维修设备
公开(公告)号：WO2006040760A2
公开(公告)日：2006-04-20
申请号：PCT/IL2005/001070
申请日：2005-10-09
申请人： SHOLEV, Mordehai , MATAR, Ebrahim , TAMIR, Ziv
发明人： SHOLEV, Mordehai , MATAR, Ebrahim , TAMIR, Ziv
IPC分类号： A61F2/958 , A61F20060101 , A61F2/00
CPC分类号： A61F2/0063 , A61F2002/0072 , A61F2220/0016 , A61F2230/0006
摘要： A method of treating hernia by means of implanting at least one collapsible mesh comprising plane body at least partially enveloped by one or more elastic collar, said rolled in an elongate open-bored applicator comprising anterior portion terminated outside the body and posterior portion located inside the body, comprising: inserting the posterior end of the applicator throughout the hernia into the wall of the abdominal cavity; releasing said mesh into said cavity while helically deploying the same such that said mesh is laying in parallel to said wall; and, ejecting said applicator.
摘要翻译：一种通过植入至少一个至少部分被一个或多个弹性套环包围的平面体的可折叠网的方法来处理疝气，所述方法包括在一个细长的开孔施放器中，所述敷料器包括终端在身体外部的前部，包括：将施放器的后端插入整个疝气进入腹腔壁; 将所述网状物释放到所述腔体中，同时螺旋地展开所述孔，使得所述网格平行于所述壁铺设; 并且喷射所述施加器。

10. 发明申请

WO2004082525A3 SINUS DELIVERY OF SUSTAINED RELEASE THERAPEUTICS 审中-公开
标题翻译： SINUS递送持续释放治疗药物
公开(公告)号：WO2004082525A3
公开(公告)日：2006-04-13
申请号：PCT/US2004007828
申请日：2004-03-12
申请人： SINEXUS INC , EATON DONALD J , MORAN MARY L , BRENNEMAN RODNEY
发明人： EATON DONALD J , MORAN MARY L , BRENNEMAN RODNEY
IPC分类号： A61F13/00 , A61F20060101 , A61F2/00 , A61K9/00 , A61L27/40 , A61L27/44 , A61L27/54 , A61L27/58 , A61M31/00
CPC分类号： A61M31/007 , A61K9/0024 , A61K9/0043 , A61K31/43 , A61K31/573 , A61K31/58 , A61K47/34
摘要： The invention provides biodegradable implants for treating sinusitis. The biodegradable implants have a size, shape, density, viscosity, and/or mucoadhesiveness that prevents them from being substantially cleared by the mucociliary lining of the sinuses during the intended treatment period. The biodegradable implants include a sustained release therapeutic, e.g., an antibiotic, a steroidal anti-inflammatory agent, or both. The biodegradable implants may take various forms, such as rods, pellets, beads, strips, or microparticles, and may be delivered into a sinus in various pharmaceutically acceptable carriers.
摘要翻译：本发明提供用于治疗鼻窦炎的可生物降解植入物。可生物降解的植入物具有尺寸，形状，密度，粘度和/或粘膜粘附性，防止在预期治疗期间鼻窦的粘膜纤毛内衬基本上被其清除。可生物降解的植入物包括持续释放治疗剂，例如抗生素，甾族抗炎药或两者。可生物降解的植入物可以采取各种形式，例如棒，丸，珠，条或微粒，并且可以递送到各种药学上可接受的载体中的窦内。

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