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1. 发明申请

WO02069689A3 GSSP4 POLYNUCLEOTIDES AND POLYPEPTIDES AND USES THEREOF 审中-公开
标题翻译： GSSP4多核苷酸和多肽及其用途
公开(公告)号：WO02069689A3
公开(公告)日：2003-02-06
申请号：PCT/IB0201514
申请日：2002-02-07
申请人： GENSET SA , BOUR BARBARA A , CHICCA JOHN , DENISON BLAKE , YEN-POTIN FRANCES , BIHAIN BERNARD , BEJANIN STEPHANE , TANAKA HIROAKI , JOBERT SEVERIN , GIORDANO JEAN-YVES , DUMAS MILNE EDWARDS JEAN-BAPTI
发明人： BOUR BARBARA A , CHICCA JOHN , DENISON BLAKE , YEN-POTIN FRANCES , BIHAIN BERNARD , BEJANIN STEPHANE , TANAKA HIROAKI , JOBERT SEVERIN , GIORDANO JEAN-YVES , DUMAS MILNE EDWARDS JEAN-BAPTI
IPC分类号： A61K38/00 , A61P3/04 , C07K14/575 , C07K14/775
CPC分类号： C07K14/5759 , A61K38/00 , C07K14/775
摘要： The present invention relates to the field of metabolic research. Metabolic disorders, such as obesity, are a public health problem that is serious and widespread. GSSP4 polypeptides have been identified that are believed to be beneficial in the treatment of metabolic disorders. These compounds should be effective for reducing cholesterol levels, body mass, body fat, and for treating metabolic-related diseases and disorders. The metabolic-related diseases or disorders envisioned to be treated by the methods of the invention include, but are not limited to, obesity, hyperlipidemia, hypercholesterolemia, atherosclerosis, diabetes, glucose intolerance, insulin resistance and hypertension.
摘要翻译：本发明涉及代谢研究领域。代谢紊乱，如肥胖，是一个严重而广泛的公共卫生问题。已经鉴定出GSSP4多肽被认为在治疗代谢紊乱中是有益的。这些化合物应有效降低胆固醇水平，体重，体脂肪，以及治疗与代谢有关的疾病和病症。预期通过本发明的方法治疗的代谢相关疾病或病症包括但不限于肥胖症，高脂血症，高胆固醇血症，动脉粥样硬化，糖尿病，葡萄糖不耐受，胰岛素抵抗和高血压。

2. 发明申请

WO02055694A3 DISCRIMINATIVE NUCLEIC ACID ANALYSIS USING CLONE SEQUENCE SIGNATURES 审中-公开
标题翻译：使用克隆序列识别的鉴定性核酸分析
公开(公告)号：WO02055694A3
公开(公告)日：2004-03-18
申请号：PCT/IB0201215
申请日：2002-01-15
申请人： GENSET SA , ERICKSON MARY RUTH , BOUR BARBARA A , BIHAIN BERNARD , TANAKA HIROAKI
发明人： ERICKSON MARY RUTH , BOUR BARBARA A , BIHAIN BERNARD , TANAKA HIROAKI
IPC分类号： C12N15/09 , A61K31/7088 , A61K31/7105 , A61K31/711 , A61K38/00 , A61K48/00 , A61P3/00 , A61P3/04 , A61P3/06 , A61P3/10 , A61P9/10 , A61P9/12 , A61P13/12 , A61P27/02 , C07K14/47 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/12 , A61K31/713 , A61K38/17 , C07K14/435
CPC分类号： A61K38/1709 , A01K2217/05 , A01K2217/075 , C07K14/47
摘要： The present invention relates to the field of metabolic research. Metabolic disorders, such as obesity, are a public health problem that is serious and widespread. GMG-3, GMG-4, Cluster 1, GMG-6A, or GMG-6B polypeptides have been identified that are beneficial in the treatment of metabolic disorders. These compounds should be effective for reducing body mass and for treating metabolic-related diseases and disorders. These metabolic-related diseases and disorders include hyperlipidemias, atherosclerosis, diabetes, and hypertension.
摘要翻译：本发明涉及代谢研究领域。代谢紊乱，如肥胖，是一个严重而广泛的公共卫生问题。已经鉴定出有益于治疗代谢紊乱的GMG-3，GMG-4，簇1，GMG-6A或GMG-6B多肽。这些化合物应该有效减少体重和治疗与代谢有关的疾病和病症。这些代谢相关的疾病和病症包括高脂血症，动脉粥样硬化，糖尿病和高血压。

3. 发明申请

WO02066505A3 GMG-3, GMG-4, AND GMG-6 POLYNUCLEOTIDES AND POLYPEPTIDES AND USES THEREOF 审中-公开
标题翻译： GMG-3，GMG-4和GMG-6多核苷酸多肽及其用途
公开(公告)号：WO02066505A3
公开(公告)日：2003-02-20
申请号：PCT/IB0201461
申请日：2002-01-15
申请人： GENSET SA , ERICKSON MARY RUTH , BOUR BARBARA A , BIHAIN BERNARD , TANAKA HIROAKI , CHU TOM , DIALYNAS DENO , SCALIA AARON
发明人： ERICKSON MARY RUTH , BOUR BARBARA A , BIHAIN BERNARD , TANAKA HIROAKI , CHU TOM , DIALYNAS DENO , SCALIA AARON
IPC分类号： C12N15/09 , A61K38/00 , A61K38/17 , A61P3/04 , A61P3/06 , A61P3/10 , A61P9/10 , A61P9/12 , C07K14/47 , C07K14/705 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C07K14/435 , A61K38/04 , C12N15/11 , C12N15/63
CPC分类号： A61K38/1709 , A01K2217/05 , A01K2217/075 , C07K14/47
摘要： The present invention relates to the field of metabolic research. Metabolic disorders, such as obesity, are a public health problem that is serious and widespread. GMG-3, GMG-4, Cluster 1, GMG-6A, or GMG-6B polypeptides have been identified that are beneficial in the treatment of metabolic disorders. These compounds should be effective for reducing body mass and for treating metabolic-related diseases and disorders. These metabolic-related diseases and disorders include hyperlipidemias, atherosclerosis, diabetes, and hypertension.
摘要翻译：本发明涉及代谢研究领域。代谢紊乱，如肥胖，是一个严重而广泛的公共卫生问题。已经鉴定出有益于治疗代谢紊乱的GMG-3，GMG-4，簇1，GMG-6A或GMG-6B多肽。这些化合物应该有效减少体重和治疗与代谢有关的疾病和病症。这些代谢相关的疾病和病症包括高脂血症，动脉粥样硬化，糖尿病和高血压。

4. 发明申请

WO02094864A3 HUMAN CDNAS AND PROTEINS AND USES THEREOF 审中-公开
标题翻译：人类CDNAS和蛋白质及其用途
公开(公告)号：WO02094864A3
公开(公告)日：2003-06-19
申请号：PCT/IB0101715
申请日：2001-08-06
申请人： GENSET SA , BEJANIN STEPHANE , TANAKA HIROAKI
发明人： BEJANIN STEPHANE , TANAKA HIROAKI
IPC分类号： G01N33/50 , A61K38/00 , A61K45/00 , A61K48/00 , A61P35/00 , A61P35/02 , A61P35/04 , A61P43/00 , C07K14/47 , C07K16/18 , C12N15/09 , C12N15/12 , C12P21/02 , C12Q1/68 , G01N33/15 , G01N33/53 , G01N33/566 , C12N9/00 , C12N15/52
CPC分类号： C07K14/4711 , A01K2217/05 , A61K38/00 , A61K48/00 , C07K14/47 , C07K2319/02 , C12Q1/6883 , G01N33/5023 , G01N33/6896 , G01N2800/2821
摘要： The invention concerns GENSET polynucleotides and polypeptides. Such GENSET products may be used as reagents in forensic analyses, as chromosome markers, as tissue/cell/organelle-specific markers, in the production of expression vectors. In addition, they may be used in screening and diagnosis assays for abnormal GENSET expression and/or biological activity and for screening compounds that may be used in the treatment of GENSET-related disorders.
摘要翻译：本发明涉及GENSET多核苷酸和多肽。在产生表达载体中，这种GENSET产品可用作法医分析中的试剂，作为染色体标记物，作为组织/细胞/细胞器特异性标志物。此外，它们可用于异常GENSET表达和/或生物活性的筛选和诊断测定，并用于筛选可用于治疗GENSET相关疾病的化合物。

5. 发明申请

WO03046180A3 HUMAN CDNAS AND PROTEINS AND USES THEREOF 审中-公开
标题翻译：人类CDNAS和蛋白质及其用途
公开(公告)号：WO03046180A3
公开(公告)日：2003-10-02
申请号：PCT/EP0213210
申请日：2002-11-25
申请人： GENSET SA , BEJANIN STEPHANE , TANAKA HIROAKI
发明人： BEJANIN STEPHANE , TANAKA HIROAKI
IPC分类号： G01N33/50 , A61K31/7088 , A61K45/00 , A61K48/00 , C07K14/47 , C07K16/18 , C12N15/09 , C12N15/12 , C12P21/02 , C12Q1/68 , G01N33/15 , G01N33/53 , G01N33/566
CPC分类号： C07K14/47
摘要： The invention concerns NOVEL polynucleotides and polypeptides. Such NOVEL products may be used as reagents in forensic analyses, as chromosome markers, as tissue/cell/organelle-specific markers, in the production of expression vectors. In addition, they may be used in screening and diagnosis assays for abnormal NOVEL expression and/or biological activity and for screening compounds that may be used in the treatment of NOVEL-related disorders.
摘要翻译：本发明涉及NOVEL多核苷酸和多肽。这些NOVEL产品可用作法医分析中的试剂，作为染色体标志物，作为组织/细胞/细胞器特异性标志物，用于表达载体的生产。另外，它们可用于异常NOVEL表达和/或生物学活性的筛选和诊断分析，以及用于筛选可用于治疗NOVEL相关病症的化合物。

6. 发明申请

WO03014151A3 HUMAN SECRETED PROTEINS, THEIR ENCODING POLYNUCLEOTIDES, AND USES THEREOF 审中-公开
标题翻译：人体分泌蛋白及其编码多核苷酸及其用途
公开(公告)号：WO03014151A3
公开(公告)日：2003-09-04
申请号：PCT/IB0102321
申请日：2001-10-15
申请人： GENSET SA , BEJANIN STEPHANE , TANAKA HIROAKI
发明人： BEJANIN STEPHANE , TANAKA HIROAKI
IPC分类号： G01N33/50 , A61K38/00 , C07K14/47 , C07K16/18 , C12N15/09 , C12P21/02 , C12Q1/68 , G01N33/15 , G01N33/68
CPC分类号： G01N33/50 , A61K38/00 , C07K14/47 , G01N33/5005 , G01N33/5008 , G01N33/502 , G01N33/68 , G01N33/6845 , G01N2500/00 , Y10T436/143333
摘要： The invention concerns GENSET polynucleotides and polypeptides. Such GENSET products may be used as reagents in forensic analyses, as chromosome markers, as tissue/cell/organelle-specific markers, in the production of expression vectors. In addition, they may be used in screening and diagnosis assays for abnormal GENSET expression and/or biological activity and for screening compounds that may be used in the treatment of GENSET-related disorders.
摘要翻译：本发明涉及GENSET多核苷酸和多肽。在产生表达载体中，这种GENSET产品可用作法医分析中的试剂，作为染色体标记物，作为组织/细胞/细胞器特异性标志物。此外，它们可用于异常GENSET表达和/或生物活性的筛选和诊断测定，并用于筛选可用于治疗GENSET相关疾病的化合物。

7. 发明申请

WO9953044A3 HIGH THROUGHPUT DNA SEQUENCING VECTOR 审中-公开
标题翻译：高通量DNA序列向量
公开(公告)号：WO9953044A3
公开(公告)日：1999-11-18
申请号：PCT/IB9900690
申请日：1999-04-09
申请人： GENSET SA , CHUMAKOV ILYA , TANAKA HIROAKI
发明人： CHUMAKOV ILYA , TANAKA HIROAKI
IPC分类号： C12N15/09 , C12N9/38 , C12N15/10 , C12N15/63 , C12N15/69 , C12Q1/68 , C12N15/64
CPC分类号： C12Q1/6841 , C12N9/16 , C12N9/2471 , C12N15/102 , C12N15/63 , C12N15/69 , C12Q1/6869 , C12Y302/01023
摘要： High throughput DNA sequencing vectors for generating nested deletions using enzymatic techniques and/or transposition-based techniques are disclosed. Methods of constructing contigs of long DNA sequences and methods of generating nested deletions are also disclosed. A truncated lacZ derivative useful in measuring the copy number of the lacZ derivative in a host cell is also disclosed.
摘要翻译：公开了用于使用酶技术和/或基于置换的技术产生嵌套缺失的高通量DNA测序载体。还公开了构建长DNA序列的重叠群的方法和产生嵌套缺失的方法。还公开了可用于测量宿主细胞中lacZ衍生物的拷贝数的截短的lacZ衍生物。

8. 发明申请

WO2009034461A2 SEMICONDUCTOR DEVICE AND WIRE BONDING METHOD 审中-公开
标题翻译：半导体器件和线路接合方法
公开(公告)号：WO2009034461A2
公开(公告)日：2009-03-19
申请号：PCT/IB2008002379
申请日：2008-09-12
申请人： TOYOTA MOTOR CO LTD , TANAKA HIROAKI
发明人： TANAKA HIROAKI
CPC分类号： H01L24/85 , H01L24/03 , H01L24/05 , H01L24/06 , H01L24/48 , H01L24/49 , H01L24/78 , H01L29/0615 , H01L29/0619 , H01L29/0638 , H01L29/0696 , H01L29/7397 , H01L2224/04042 , H01L2224/05552 , H01L2224/05553 , H01L2224/05554 , H01L2224/05556 , H01L2224/05599 , H01L2224/0603 , H01L2224/4807 , H01L2224/48091 , H01L2224/4813 , H01L2224/48137 , H01L2224/48458 , H01L2224/4846 , H01L2224/48471 , H01L2224/4903 , H01L2224/49051 , H01L2224/4911 , H01L2224/78313 , H01L2224/78318 , H01L2224/85181 , H01L2224/85399 , H01L2924/00014 , H01L2924/01004 , H01L2924/01005 , H01L2924/01006 , H01L2924/01015 , H01L2924/01033 , H01L2924/01082 , H01L2924/1305 , H01L2924/13055 , H01L2224/45099 , H01L2924/00 , H01L2924/00012
摘要： A semiconductor device (2) includes: a FLR (65) that is disposed on a semiconductor substrate so as to divide the semiconductor substrate into an inner region and an outer region; a first bonding pad (24a to 24d) that is disposed in the inner region and is connected to an external circuit by a wire (14a to 14d) whose one end is connected to the external circuit; and a second bonding pad (26a to 26d) that is disposed in the outer region and on which the other end of the wire is bonded.
摘要翻译：半导体器件（2）包括：FLR（65），其设置在半导体衬底上以将半导体衬底分成内部区域和外部区域; 第一焊盘（24a〜24d），其设置在所述内部区域中，并且通过一端连接到所述外部电路的导线（14a至14d）连接到外部电路; 以及设置在所述外部区域中并且所述电线的另一端接合在其上的第二接合焊盘（26a至26d）。

9. 发明申请

WO2008059350A3 SEMICONDUCTOR DEVICE AND METHOD FOR PRODUCTION THEREOF 审中-公开
标题翻译：半导体器件及其制造方法
公开(公告)号：WO2008059350A3
公开(公告)日：2008-07-10
申请号：PCT/IB2007003477
申请日：2007-11-13
申请人： TOYOTA MOTOR CO LTD , TANAKA HIROAKI
发明人： TANAKA HIROAKI
IPC分类号： H01L29/739 , H01L21/331 , H01L29/10
CPC分类号： H01L29/7397 , H01L29/1095 , H01L29/66348
摘要： A semiconductor device has a drift region (20) (third semiconductor region) of an n-type (first conductivity type); a body region (50) (second semiconductor region) of a p-type (second conductivity type) provided on the drift region (20); an emitter region (60) (first semiconductor region) of the n-type formed in the top surface of the body region (50) and separated from the drift region (20) by the body region (50); a trench (14) extending from the top surface of the emitter region (60) through the body region (50) into the drift region (20); a trench gate electrode (13) filled in the trench (14); and a semiconductor region (70) (fourth semiconductor region) of the p-type formed in contact with side faces of the trench protruding into the drift region (20). Therefore, the semiconductor device can suppress a surge voltage at turn-off, and can be produced easily.
摘要翻译：半导体装置具有n型（第1导电型）的漂移区域（20）（第3半导体区域）设置在漂移区域20上的p型（第2导电型）的体区域50（第2半导体区域）形成在本体区域50的上表面中且通过本体区域50与漂移区域20分离的n型发射极区域60（第一半导体区域）; 从发射极区域（60）的顶部表面穿过体区域（50）延伸到漂移区域（20）中的沟槽（14）; 填充在沟槽（14）中的沟槽栅电极（13）; 和形成为与突出到漂移区（20）中的沟槽的侧面接触的p型的半导体区域（70）（第四半导体区域）。因此，半导体器件可以抑制关断时的浪涌电压，并且可以容易地产生。

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