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1. 发明申请

WO9846907A2 METHOD AND APPARATUS FOR OPERATING A CLUTCH IN AN AUTOMATED MECHANICAL TRANSMISSION 审中-公开
标题翻译：用于在自动机械传动中操作离合器的方法和装置
公开(公告)号：WO9846907A2
公开(公告)日：1998-10-22
申请号：PCT/US9807606
申请日：1998-04-15
申请人： TRANSMISSION TECHNOLOGIES CORP , PATEL ANAND C , WHEELER JAMES A , SZYMANSKI PETER T
发明人： PATEL ANAND C , WHEELER JAMES A , SZYMANSKI PETER T
IPC分类号： B60W10/02 , B60W10/06 , B60W30/18 , F16D48/06 , F16H61/66 , F16H
CPC分类号： B60W10/06 , B60W10/02 , B60W10/10 , B60W30/18 , B60W2510/0216 , B60W2510/0638 , B60W2510/0657 , B60W2710/023 , F16D48/066 , F16D2500/10412 , F16D2500/1083 , F16D2500/3026 , F16D2500/30401 , F16D2500/30415 , F16D2500/3065 , F16D2500/3067 , F16D2500/30825 , F16D2500/3144 , F16D2500/7041 , F16D2500/70454 , F16H61/66
摘要： An apparatus and method for controlling the operation of a clutch in a partially or fully automated mechanical transmission which is responsive to the actual load on the vehicle engine for varying the engagement rate of release bearing during re-engagement of the clutch. The apparatus includes an electronic controller which initially sets a desired speed for the vehicle engine during the shifting process, determines a rate of engagement movement of a release bearing of the clutch, and actuates appropriate valves to initiate the gradual engagement of the clutch. The electronic controller sets a first lower engine speed threshold and a second lower engine speed threshold. In a first embodiment, the magnitude of the first lower engine speed threshold varies with the actual load on the engine. If the actual speed of the engine remains above both the first lower engine speed threshold and the second lower engine speed threshold, the engagement process is continued without interruption. If the actual speed of the engine drops below the first lower engine speed threshold but remains above the second lower engine speed threshold, the release bearing is held in its current position until the actual speed of the engine recovers above the first lower engine speed threshold. If the actual speed of the engine drops below both the first lower engine speed threshold and the second lower engine speed threshold, the engagement process is aborted, and the release bearing is returned to the disengaged position until the actual speed of the engine recovers above an engagement re-start speed threshold. In a second embodiment, the magnitude of the first lower engine speed threshold varies with both the actual load on the engine and the amount of depression of an accelerator pedal of the vehicle.
摘要翻译：一种用于控制部分或全自动机械变速器中的离合器的操作的装置和方法，其响应于车辆发动机上的实际负载，以在离合器的再接合期间改变释放轴承的接合速率。该装置包括电子控制器，其在换档过程期间初始设定车辆发动机的期望速度，确定离合器的释放轴承的接合运动速率，并且启动适当的阀以启动离合器的逐渐接合。电子控制器设置第一较低的发动机转速阈值和第二较低的发动机转速阈值。在第一实施例中，第一较低发动机转速阈值的大小随着发动机上的实际负载而变化。如果发动机的实际速度保持高于第一较低发动机速度阈值和第二较低发动机转速阈值，则接合过程继续而不间断。如果发动机的实际速度低于第一较低的发动机速度阈值，但是保持在第二较低的发动机速度阈值之上，则释放轴承保持在其当前位置，直到发动机的实际速度恢复到高于第一较低的发动机转速阈值。如果发动机的实际速度低于第一较低发动机速度阈值和第二较低发动机速度阈值，则接合过程被中止，并且释放轴承返回到脱离位置，直到发动机的实际速度恢复到高于接合重启速度阈值。在第二实施例中，第一较低发动机速度阈值的大小随着发动机上的实际负载和车辆的加速器踏板的下压量而变化。

2. 发明申请

WO9846908A2 METHOD AND APPARATUS FOR OPERATING A CLUTCH IN AN AUTOMATED MECHANICAL TRANSMISSION 审中-公开
标题翻译：用于在自动机械传动中操作离合器的方法和装置
公开(公告)号：WO9846908A2
公开(公告)日：1998-10-22
申请号：PCT/US9807607
申请日：1998-04-15
申请人： TRANSMISSION TECHNOLOGIES CORP , BAER KURT R , PATEL ANAND C , WHEELER JAMES A
发明人： BAER KURT R , PATEL ANAND C , WHEELER JAMES A
IPC分类号： B60W10/02 , B60W10/06 , B60W30/18 , F16D48/06 , F16H
CPC分类号： B60W10/06 , B60W10/02 , B60W10/10 , B60W30/18 , B60W2510/0216 , B60W2510/0657 , B60W2540/106 , B60W2710/023 , F16D48/066 , F16D2500/3026 , F16D2500/30415 , F16D2500/3065 , F16D2500/30825 , F16D2500/3144 , F16D2500/50251 , F16D2500/50281 , F16D2500/7041 , Y10T477/70 , Y10T477/75 , Y10T477/78
摘要： An apparatus and method for performing a kiss point determining algorithm which is responsive to the approach rate of the release bearing of a clutch for performing the algorithm only under reliable operating conditions. The apparatus includes an electronic controller which sets an approach rate for engaging the clutch in response to the amount of depression of the accelerator pedal of the vehicle by the operator. The amount of engine torque or other engine operating conditions are measured and compared against a predetermined magnitude which is indicative of the onset of engagement of the clutch. When an increase of a predetermined magnitude is detected the accelerator pedal position is compared against a predetermined value. If the accelerator pedal is depressed more than the predetermined value, the kiss point is re-defined as the current location of the release bearing. If the accelerator pedal is not depressed more than the predetermined value, the kiss point is not re-defined.
摘要翻译：一种用于执行吻点确定算法的装置和方法，其响应于仅在可靠的操作条件下执行算法的离合器的释放轴承的接近速率。该装置包括电子控制器，该电子控制器响应于操作者对车辆的加速踏板的下压量设定接合速度。测量发动机转矩或其他发动机工作条件的量，并将其与指示离合器接合开始的预定幅度进行比较。当检测到预定大小的增加时，将加速器踏板位置与预定值进行比较。如果加速踏板被压下超过预定值，则接吻点被重新定义为释放轴承的当前位置。如果加速踏板没有按压超过预定值，则不会重新定义接吻点。

3. 发明申请

WO2014015056A2 ANTI-MUCUS DRUGS AND USES THEREFOR 审中-公开
标题翻译：抗粘液药物及其用途
公开(公告)号：WO2014015056A2
公开(公告)日：2014-01-23
申请号：PCT/US2013/050921
申请日：2013-07-17
申请人： WASHINGTON UNIVERSITY , HOLTZMAN, Michael J. , ROMERO, Arthur D. , ALEVY, Yael G. , PATEL, Anand C. , BRETT, Tom J. , PATEL, Dhara
发明人： HOLTZMAN, Michael J. , ROMERO, Arthur D. , ALEVY, Yael G. , PATEL, Anand C. , BRETT, Tom J. , PATEL, Dhara
CPC分类号： C07D417/14 , C07D401/12 , C07D405/14 , C07D409/14 , C07D417/12 , C07D471/04 , C07D491/048
摘要： Disclosed are methods of identifying, generating and synthesizing compounds that inhibit MAPK13 activity. In various embodiments, compounds, salts thereof and prodrugs thereof of the present teachings can be useful for the treatment of diseases and disorders that involve excess mucus production.
摘要翻译：公开了鉴定，产生和合成抑制MAPK13活性的化合物的方法。在各种实施方案中，本教导的化合物，其盐及其前药可用于治疗涉及过量粘液产生的疾病和病症。

4. 发明申请

WO2014015056A3 ANTI-MUCUS DRUGS AND USES THEREFOR 审中-公开
标题翻译：抗神经药物及其用途
公开(公告)号：WO2014015056A3
公开(公告)日：2014-04-03
申请号：PCT/US2013050921
申请日：2013-07-17
申请人： UNIV WASHINGTON , HOLTZMAN MICHAEL J , ROMERO ARTHUR D , ALEVY YAEL G , PATEL ANAND C , BRETT TOM J , PATEL DHARA
发明人： HOLTZMAN MICHAEL J , ROMERO ARTHUR D , ALEVY YAEL G , PATEL ANAND C , BRETT TOM J , PATEL DHARA
IPC分类号： C07D401/12 , A61K31/437 , A61K31/4427 , A61K31/4439 , A61K31/5377 , A61K31/541 , A61P11/06 , A61P11/12 , C07D405/14 , C07D409/14 , C07D417/12 , C07D471/04 , C07D491/048 , C12N15/00 , G01N33/66
CPC分类号： C07D417/14 , C07D401/12 , C07D405/14 , C07D409/14 , C07D417/12 , C07D471/04 , C07D491/048
摘要： Disclosed are methods of identifying, generating and synthesizing compounds that inhibit MAPK13 activity. In various embodiments, compounds, salts thereof and prodrugs thereof of the present teachings can be useful for the treatment of diseases and disorders that involve excess mucus production.
摘要翻译：公开了鉴定，产生和合成抑制MAPK13活性的化合物的方法。在各种实施方案中，本发明的化合物，其盐和其前药可用于治疗涉及过量粘液产生的疾病和病症。

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