专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2014048564A8 "NOVEL CROSS-LINKERS FOR HYDROGELS, HYDROGELS INCLUDING THESE CROSS-LINKERS AND APPLICATIONS THEREOF" 审中-公开
标题翻译： “HYDROGELS，HYDROGELS，包括这些交叉连接器及其应用的新交叉连接器”
公开(公告)号：WO2014048564A8
公开(公告)日：2014-05-30
申请号：PCT/EP2013002876
申请日：2013-09-25
申请人： MAX PLANCK GES ZUR FÖRDERUNG DER WISSENSCHAFTEN E V
发明人： BÖHM HEIKE , HAGEL VALENTIN , MUNDINGER TABEA , NUSS ISABELL , WEGNER SERAPHINE VALESKA , LASCHAT SABINE , MATEESCU MARKUS MANFRED
IPC分类号： C07D213/80 , A61K31/4425 , A61P43/00 , C07D213/82 , C08B37/08
CPC分类号： C08J3/24 , C07D213/80 , C07D213/82 , C08B37/0072 , C08J3/075 , C08J2305/08 , C08L5/08 , C08L1/02 , C08L5/02 , C08L5/04 , C08L53/00 , C08L67/04 , C08L71/02
摘要： The present invention relates to novel cross-linkers for hydrogels, in particular for hyaluronan hydrogels, corresponding hydrogels including said cross-linkers and various applications thereof. The cross linker of the invention is a bi- or multifunctional cross-linker comprising or consisting of an aromatic or heteroaromatic ring system with 3-6 C atoms which is coupled via functional groups on at least 2 ring positions with at least 2 terminal groups capable to form a covalent bond with thiol or amino groups, in particular with thiol groups in a thiol-en reaction. The cross-linker may be charged or uncharged. In a specific embodiment, the terminal groups are coupled to carboxy groups of the aromatic or heteroaromatic ring system via an ester or amide bond. More specifically, the cross-linker of the invention is a derivative of pyridine-3, 5-dicarboxylic acid or a corresponding pyridinium salt thereof wherein 2 terminal groups are coupled to the carboxy groups of the pyridine or pyridinium core via an ester or amide bond. In a preferred embodiment, the cross-linker is N3,N5-bis(2-acrylamidoethyl) pyridine-3, 5-dicarboxamide or a 3,5-bis((2-acrylamidoethyl) carbamoyl) -1-methylpyridin-l-ium-halogenide.
摘要翻译：本发明涉及用于水凝胶，特别是透明质酸水凝胶的新型交联剂，包括所述交联剂的相应水凝胶及其各种应用。本发明的交联剂是包含或由具有3-6个C原子的芳族或杂芳族环系统组成的双官能或多功能交联剂，其通过官能团在至少2个环位置与至少2个具有端基的基团与硫醇或氨基形成共价键，特别是在硫醇-en反应中与硫醇基形成共价键。交联剂可以带电或不带电。在具体实施方案中，末端基团通过酯或酰胺键与芳族或杂芳族环系的羧基偶联。更具体地，本发明的交联剂是吡啶-3,5-二羧酸或其相应的吡啶鎓盐的衍生物，其中2个末端基通过酯或酰胺键与吡啶或吡啶鎓核心的羧基偶联。在优选的实施方案中，交联剂是N 3，N 5 - 双（2-丙烯酰胺基乙基）吡啶-3,5-二甲酰胺或3,5-双（（2-丙烯酰胺基乙基）氨基甲酰基）-1-甲基吡啶-1- -halogenide。

2. 发明申请

WO2014147525A3 PERYLENEMONOIMIDE AND NAPHTHALENEMONOIMIDE DERIVATIVES AND THEIR USE IN DYE-SENSITIZED SOLAR CELLS 审中-公开
标题翻译：环戊二烯和萘磺隆衍生物及其在染料敏化太阳能电池中的应用
公开(公告)号：WO2014147525A3
公开(公告)日：2015-04-16
申请号：PCT/IB2014059678
申请日：2014-03-12
申请人： BASF SE , BASF CHINA CO LTD , MAX PLANCK GES ZUR FÖRDERUNG DER WISSENSCHAFTEN E V
发明人： WONNEBERGER HENRIKE , PSCHIRER NEIL GREGORY , BENEDITO FLAVIO LUIZ , BRUDER INGMAR , SEND ROBERT , ZAGRANYARSKI YULIAN , LI CHEN , MÜLLEN KLAUS , CHEN LONG , SKABEEV ARTEM NIKOLAEVICH
IPC分类号： C07C15/56 , C07D403/12 , C07D413/12 , H01L51/00 , H01L51/50
CPC分类号： C07D491/06 , C07D221/04 , C07D471/06 , C07D493/06 , C07D495/06 , C09B5/62 , C09B57/08 , H01G9/2031 , H01G9/2059 , H01L51/0053 , H01L51/006 , H01L51/0061 , H01L51/4226 , Y02E10/542 , Y02E10/549 , Y02P70/521
摘要： Disclosed is the use of compounds of general foRmula (I), wherein the variables have the meaning given in the description in dye-sensitized solar cells; to compounds of general formula (I'), wherein the variables have the meaning given in the description; to compounds of general formula (I"), wherein the variables have the meaning given in the description; to the use of compounds of general formula (II), in the case of q equal to 0 or 1 : as precursor compounds for the manufacture of compounds of general formula (I) and in the case of q equal to 1: as precursor compounds for the manufacture of compounds of general formula (I') wherein the remaining variables have the meaning given in the description; to compounds of general formula (III), wherein the variables have the meaning given in the description; to the use of compounds of general formula (I), (I') or (I") as sensitizers in dye-sensitized solar cells; and to such dye-sensitized solar cells per se.
摘要翻译：公开了一般化合物（I）的化合物的用途，其中变量具有染料敏化太阳能电池中描述中给出的含义; 到通式（I'）的化合物，其中变量具有在说明书中给出的含义; 对于通式（I“）的化合物，其中变量具有说明书中给出的含义;在q等于0或1的情况下使用通式（II）的化合物作为制备的前体化合物的通式（I）的化合物和q等于1的情况下作为用于制备通式（I'）的化合物的前体化合物，其中剩余的变量具有本说明书给出的含义;通式（III），其中变量具有说明书中给出的含义;在染料敏化太阳能电池中使用通式（I），（I'）或（I“）的化合物作为敏化剂; 以及染料敏化太阳能电池本身。

3. 发明申请

WO2014096136A3 REACTION VESSEL FOR SAMPLE PREPARATION 审中-公开
标题翻译：用于样品制备的反应容器
公开(公告)号：WO2014096136A3
公开(公告)日：2014-09-04
申请号：PCT/EP2013077297
申请日：2013-12-19
申请人： MAX PLANCK GES ZUR FÖRDERUNG DER WISSENSCHAFTEN E V
发明人： KULAK NILS A , MANN MATTHIAS , AZIMIFAR SEYED BABAK , NAGARAJ NAGARJUNA
IPC分类号： B01L3/00 , B01D15/22 , G01N30/02 , G01N30/60
CPC分类号： G01N1/405 , B01D15/12 , B01D15/125 , B01D15/22 , B01L3/502 , B01L2200/0631 , B01L2300/042 , B01L2300/044 , B01L2300/047 , B01L2300/069 , C12N15/101 , G01N33/6842
摘要： The present invention relates to sample preparation container for purification and/or enrichment of bio-organic compounds from cellular material, viruses and/or sub-components of said cellular material and/or viruses, the container comprising a reaction chamber and a chromatography medium; wherein said reaction chamber is for holding said cellular material, viruses and/or sub-components of said cellular material and/or viruses and is configured such that at least one of the following reactions can be performed therein: lyis, e.g. by sonication and/or boiling; chromatographic purification; reduction; alkylation; and enzymatic reactions such as proteolysis; wherein said chromatography medium is configured to purify and/or enrich said bio-organic compounds; wherein (a) said chromatography medium is located at a wall of said reaction chamber, and said wall is closed or sealed and configured to be opened for obtaining purified and/or enriched bio-organic compounds; or (b) said sample preparation container further comprises a receiving chamber for receiving said bio-organic compounds, said receiving chamber being adjacent to said chromatography medium such that said chromatography medium separates said reaction chamber from said receiving chamber, and the outer face of said receiving chamber is closed and configured to be opened for obtaining purified and/or enriched bio-organic compounds.
摘要翻译：本发明涉及用于从所述细胞材料和/或病毒的细胞材料，病毒和/或亚组分纯化和/或富集生物有机化合物的样品制备容器，所述容器包括反应室和色谱介质; 其中所述反应室用于保持所述细胞材料，所述细胞材料和/或病毒的病毒和/或亚组分，并且被配置为使得可以在其中进行至少一个以下反应：通过超声处理和/或煮沸; 色谱纯化; 减少; 烷基化; 和酶反应如蛋白水解; 其中所述色谱介质被配置为净化和/或富集所述生物有机化合物; 其中（a）所述色谱介质位于所述反应室的壁处，并且所述壁被封闭或密封并构造成打开以获得纯化和/或富集的生物有机化合物; 或（b）所述样品制备容器还包括用于接收所述生物有机化合物的接收室，所述接收室与所述色谱介质相邻，使得所述色谱介质将所述反应室与所述接收室分离，并且所述接收室被关闭并被构造成打开以获得纯化和/或富集的生物有机化合物。

4. 发明申请

WO2013167661A3 DISASTER ALERT MEDIATION USING NATURE 审中-公开
标题翻译：使用自然的灾难警报调解
公开(公告)号：WO2013167661A3
公开(公告)日：2014-05-01
申请号：PCT/EP2013059606
申请日：2013-05-08
申请人： MAX PLANCK GES ZUR FÖRDERUNG DER WISSENSCHAFTEN E V
发明人： WIKELSKI MARTIN , MÜLLER USCHI , HEIDRICH WOLFGANG ARNE , KÜMMETH FRANZ XAVER
IPC分类号： G01V1/00
CPC分类号： G01W1/10 , A61B5/02055 , A61B5/0476 , A61B5/16 , A61B5/42 , G01V1/008 , G06Q50/265
摘要： The present invention relates to a method for forecasting an environmental event/a type of environmental event comprising the steps of: acquiring at least one test data set of at least one behavioural and/or physiological parameter of a population of animals; generating a test profile based on said at least one test data set, representing behaviour and/or physiological status of the population of animals; calculating a ratio between the test profile and a first reference profile; and setting an alert, if said ratio reaches a predefined threshold value. The present invention further relates to a system for forecasting an environmental event/a type of environmental event comprising at least one data acquisition unit configured to acquire at least one data set of at least one behavioural and/or physiological parameter of a population of animals; at least one profile generation unit configured to generate at least one first reference profile and / or at least one test profile wherein each profile is based on at least one data set; at least one ratio calculation unit configured to calculate at least one ratio between the at least one test profile and one of the at least one first reference profile; at least one alert unit configured to raise an alert if at least one of the at least one calculated ratio reaches a predefined threshold value. The present invention also relates to a computer program product comprising one or more computer readable media having computer executable instructions for performing the steps of the method for forecasting an environmental event/a type of environmental event.
摘要翻译：本发明涉及一种用于预测环境事件/环境事件的类型的方法，包括以下步骤：获取动物群体的至少一个行为和/或生理参数的至少一个测试数据集; 基于所述至少一个测试数据集生成表示动物群体的行为和/或生理状态的测试概况; 计算测试轮廓和第一参考轮廓之间的比率; 并且如果所述比率达到预定义的阈值，则设置警报。本发明还涉及一种用于预测环境事件/一种环境事件的系统，该系统包括：至少一个数据获取单元，被配置为获取至少一个动物群体的行为和/或生理参数的数据集; 至少一个简档生成单元被配置为生成至少一个第一参考简档和/或至少一个测试简档，其中每个简档基于至少一个数据集; 至少一个比率计算单元，被配置为计算所述至少一个测试轮廓与所述至少一个第一参考轮廓中的一个之间的至少一个比率; 至少一个警报单元，被配置为如果所述至少一个所计算的比率中的至少一个达到预定义的阈值，则提醒警报。本发明还涉及一种包括具有计算机可执行指令的一个或多个计算机可读介质的计算机程序产品，用于执行用于预测环境事件/环境事件类型的方法的步骤。

5. 发明申请

WO2014033622A3 CONVENIENTLY PREPARED NAPHTHALENE AND PERYLENE DERIVATIVES AS BUILDING BLOCKS FOR ORGANIC ELECTRONIC MATERIALS AND DYESTUFF 审中-公开
标题翻译：方便制备的萘和芘衍生物作为建筑块用于有机电子材料和染料
公开(公告)号：WO2014033622A3
公开(公告)日：2014-04-24
申请号：PCT/IB2013058009
申请日：2013-08-27
申请人： BASF SE , MAX PLANCK GES ZUR FÖRDERUNG DER WISSENSCHAFTEN E V , BASF CHINA CO LTD
发明人： GESSNER THOMAS , REICHELT HELMUT , ZAGRANYARSKI YULIAN , CHEN LONG , LI CHEN , MÜLLEN KLAUS
IPC分类号： C07C13/32 , C07C43/18 , C07C69/753 , C07C211/42 , C07C255/47 , C07C319/14 , C07C321/22 , C07D339/00
CPC分类号： C07D495/06 , C07C25/22 , C07C41/01 , C07C41/16 , C07C41/22 , C07C43/29 , C07C67/08 , C07C69/76 , C07C253/30 , C07C255/52 , C07C2603/52 , C07F7/0818 , C09B1/00 , C09B3/14 , C09B3/18 , C09B3/20 , C09B5/026 , H01L51/0055 , H01L51/0074 , H01L51/0094 , H01L51/05 , H01L51/42 , H01L51/50
摘要： The present invention provides the compounds of formulae ( 3 ) and (1), wherein n is 0 or 1, R11 and R12 are the same and are selected from the group consisting of CN, OR300, Si(R301)3, NHR302, NR303R304, SR305 and R306, or R11 and R12 together are selected from the group consisting of (a), (b), and (c) and X is Cl, Br or I, and a process for the preparation of compounds of formula (3) comprising the compounds of formula (1) as key intermediates.
摘要翻译：本发明提供了式（3）和（1）的化合物，其中n是0或1，R 11和R 12是相同的并且选自CN，OR 300，Si（R 301）3，NHR 302，NR 303 R 304 ，SR305和R306或R11和R12一起选自（a），（b）和（c）且X为Cl，Br或I，以及制备式（3））包含式（1）的化合物作为关键中间体。

6. 发明申请

WO2015144282A8 INORGANIC-ORGANIC HYBRID COMPOUND 审中-公开
标题翻译：无机复合有机化合物
公开(公告)号：WO2015144282A8
公开(公告)日：2016-08-04
申请号：PCT/EP2015000454
申请日：2015-02-26
申请人： KARLSRUHER INST FÜR TECHNOLOGIE , MAX PLANCK GES ZUR FÖRDERUNG DER WISSENSCHAFTEN E V , GEORG AUGUST UNIVERSITÄT STIFTUNG ÖFFENTLICHEN RECHTS UNIVERSITÄTSMEDIZIN
发明人： HECK JOACHIM , POSS MARIEKE , REICHARDT HOLGER , NAPP JOANNA , ALVES FRAUKE , STÜHMER WALTER , FELDMANN CLAUS
IPC分类号： C07F7/00 , C07C237/26 , C07C309/47 , C07C309/50 , C07D401/04 , C07D401/10 , C07D403/10 , C07D407/12 , C07D413/04 , C07D417/10 , C07D417/12 , C07D493/10 , C07F5/06 , C07F9/09 , C07F9/117 , C07F9/12 , C07F9/30 , C07F9/38 , C07F9/58 , C07F9/6503 , C07F9/6506 , C07F9/6509 , C07F9/6533 , C07F9/655 , C07F9/6558 , C07F9/6561 , C07F9/6574 , C07H19/00
CPC分类号： A61K49/0041 , A61K31/185 , A61K31/427 , A61K31/519 , A61K31/546 , A61K31/569 , A61K31/65 , A61K31/661 , A61K31/6615 , A61K31/662 , A61K31/663 , A61K31/665 , A61K31/675 , A61K31/683 , A61K31/7008 , A61K31/704 , A61K31/7056 , A61K31/7068 , A61K31/7076 , A61K38/12 , A61K47/02 , A61K49/0021 , A61K49/0032 , A61K49/0034 , A61K49/0036 , C07C237/26 , C07C309/47 , C07C2603/46 , C07D251/50 , C07D401/04 , C07D401/10 , C07D403/10 , C07D407/12 , C07D413/04 , C07D417/10 , C07D417/12 , C07D493/10 , C07F5/069 , C07F7/006 , C07F9/091 , C07F9/117 , C07F9/12 , C07F9/301 , C07F9/3813 , C07F9/3873 , C07F9/582 , C07F9/65033 , C07F9/65061 , C07F9/650958 , C07F9/65335 , C07F9/65505 , C07F9/65515 , C07F9/65517 , C07F9/65522 , C07F9/65583 , C07F9/65586 , C07F9/6561 , C07F9/65744 , C07F9/65746 , C07J1/0033 , C07J51/00 , C09B1/02 , C09B1/52 , C09B11/08 , C09B19/00 , C09B23/06 , C09B23/086 , C09B29/16 , C09B31/072 , C09B31/08 , C09B35/023 , C09B55/006 , C09B55/009 , C09B57/00 , C09B57/02 , C09B57/08 , C09B62/085 , C09B63/005
摘要： The invention relates to an inorganic-organic hybrid compound as an ion compound, composed of an inorganic cation and an organic anion active substance and optionally, an organic anion fluorescent dye.
摘要翻译：本发明涉及一种有机 - 无机混合化合物作为无机阳离子组成的离子性化合物和有机Wirkstoffanion和任选的有机Fluoreszenzfarbstoffanion。

7. 发明申请

WO2016030004A3 HIGH VOLTAGE FEEDTHROUGH ASSEMBLY, TIME-RESOLVED TRANSMISSION ELECTRON MICROSCOPE AND METHOD OF ELECTRODE MANIPULATION IN A VACUUM ENVIRONMENT 审中-公开
标题翻译：高压馈电组件，时间分辨透射电子显微镜及真空环境中电极手术的方法
公开(公告)号：WO2016030004A3
公开(公告)日：2016-04-21
申请号：PCT/EP2015001685
申请日：2015-08-14
申请人： MAX PLANCK GES ZUR FÖRDERUNG DER WISSENSCHAFTEN E V
发明人： HIRSCHT JULIAN
IPC分类号： H01J37/02 , H01J37/065 , H01J37/073 , H01J37/26 , H01J37/295
CPC分类号： H01J37/023 , H01J37/065 , H01J37/073 , H01J37/26 , H01J37/295 , H01J2237/06333 , H01J2237/06341 , H01J2237/16
摘要： A high voltage feedthrough assembly (100) for providing an electric potential in a vacuum environment comprises a flange connector (10) being adapted for a connection with a vacuum vessel (201), wherein the flange connector (10) has an inner side (11) facing to the vacuum vessel (201) and an outer side (12) facing to an environment of the vacuum vessel 201, a vacuumtight insulator tube (20) having a longitudinal extension with a first end (21) facing to the flange connector (10) and a second end (22) being adapted for projecting into the vacuum vessel (201), and an electrode device (30) coupled to the second end (22) of the insulator tube (20), wherein the electrode device (30) has a front electrode (31), including a photocathode or a field emitter tip and facing to the vacuum vessel (201) and a cable adapter (32) for receiving a high-voltage cable (214), wherein a flexible tube connector (40) is provided for a vacuum-tight coupling of the insulator tube (20) with the flange connector (10), and a manipulator device (50) is connected with the insulator tube (20) for adjusting a geometrical arrangement of the insulator tube (20) relative to the flange connector (10). Furthermore, an electron diffraction or imaging apparatus (transmission electron microscope, TEM) 200 for static and/or time-resolved diffraction, including (nano-) crystallography, and real space imaging for structural investigations including the high voltage feedthrough assembly (100) and a method of manipulating an electrode device (30) in a vacuum environment are described.
摘要翻译：一种用于在真空环境中提供电势的高压馈通组件（100）包括适于与真空容器（201）连接的法兰连接器（10），其中法兰连接器（10）具有内侧（11 ）面向真空容器（201）和面向真空容器201的环境的外侧（12）;具有纵向延伸部的真空密封绝缘管（20），其第一端（21）面向法兰连接器（20）的第二端（22）连接的电极装置（30），其中所述电极装置（30）与所述绝缘管（20）的第二端）具有包括光电阴极或场发射器尖端且面向真空容器（201）的前电极（31）和用于接收高压电缆（214）的电缆适配器（32），其中柔性管连接器 40）用于绝缘管（20）与法兰连接器的真空密封连接（10），操纵器装置（50）与绝缘管（20）连接，用于调节绝缘管（20）相对于法兰连接器（10）的几何布置。此外，用于静态和/或时间分辨衍射（包括（纳米）晶体学）的电子衍射或成像装置（透射电子显微镜，TEM）200，以及用于包括高压馈通组件（100）的结构研究的真实空间成像和描述了在真空环境中操纵电极装置（30）的方法。

8. 发明申请

WO2015117748A8 METHOD AND DEVICES FOR X-RAY CRYSTALLOGRAPHY, IN PARTICULAR WITH MICROCRYSTALS OF BIOLOGICAL MACROMOLECULES 审中-公开
标题翻译：用于X射线晶体学的方法和装置，特别是具有生物大分子微晶的方法和装置
公开(公告)号：WO2015117748A8
公开(公告)日：2015-10-15
申请号：PCT/EP2015000208
申请日：2015-02-03
申请人： MAX PLANCK GES ZUR FÖRDERUNG DER WISSENSCHAFTEN E V , UNIV ARIZONA
发明人： DOAK ROBERT BRUCE , SHOEMAN ROBERT , BOTHA SABINE , SCHLICHTING ILME , BARENDS THOMAS R M , NASS KAROL
IPC分类号： G01N23/20
CPC分类号： G01N23/207 , G01N23/20 , G01N23/20008 , G01N2223/31 , G01N2223/612
摘要： A method of X-ray crystallography for investigating microscopic crystals, in particular microscopic crystals of biological macromolecules, comprises the steps of extruding a sample stream (1) with an injector nozzle device (100), wherein the sample stream (1) comprises a viscous liquid with microscopic crystals embedded therein, providing an X-ray beam (2) with a synchrotron source device (210) and irradiating the sample stream (1) with the X-ray beam (2), and collecting diffraction image data created by diffraction of the X-ray beam (2) by the microscopic crystals with a series of X-ray exposures of the sample stream (1). Furthermore, an injector nozzle device (100) and an X-ray crystallography apparatus (200) for X-ray crystallography investigations of microscopic crystals are described.
摘要翻译：用于研究微观晶体（特别是生物大分子的微观晶体）的X-射线晶体学方法包括用喷射器喷嘴装置（100）挤出样品流（1）的步骤，其中样品流（1）包括粘性在其中嵌入微晶体的液体，用同步加速器源装置（210）提供X射线束（2）并用X射线束（2）照射样品流（1），并收集由衍射产生的衍射图像数据通过样品流（1）的一系列X射线照射通过显微镜晶体检测X射线束（2）的X射线。此外，描述了用于微观晶体的X射线晶体学研究的注射器喷嘴装置（100）和X射线晶体学装置（200）。

9. 发明申请

WO2014033620A3 DOUBLE DONOR FUNCTIONALISATION OF THE PERI-POSITIONS OF PERYLENE AND NAPHTHALENE MONOIMIDE VIA VERSATILE BUILDING BLOCKS 审中-公开
标题翻译：通过多层建筑块对季戊四醇和萘二甲酸单体进行双官能双功能化
公开(公告)号：WO2014033620A3
公开(公告)日：2014-04-24
申请号：PCT/IB2013058005
申请日：2013-08-27
申请人： BASF SE , MAX PLANCK GES ZUR FÖRDERUNG DER WISSENSCHAFTEN E V , BASF CHINA CO LTD
发明人： WONNEBERGER HENRIKE , REICHELT HELMUT , ZAGRANYARSKI YULIAN , LI CHEN , MÜLLEN KLAUS , CHEN LONG
IPC分类号： C07D221/14 , C07D311/94
CPC分类号： C07D491/06 , C07D221/18 , C07D239/70 , C07D311/78 , C07D311/92 , C07D471/06 , C09B5/62 , C09B57/08 , H01G9/2031 , H01G9/2059 , H01L51/0053 , H01L51/0061 , Y02B10/10 , Y02E10/542
摘要： The present invention provides the compounds of formulae (3) and (1 ) wherein n is 0 or 1, R13 and R14 are the same or different and are selected from the group consisting of NHR310, NR311R312, OR313, SR314 and R315, or R13 and R14 together are selected from the group consisting of (a), (b) and (c), and X is CI, Br ot I, and a process for the preparation of compounds of formula (3) comprising the compounds of formula (1 ) as key intermediates.
摘要翻译：本发明提供式（3）和（1）的化合物，其中n为0或1，R 13和R 14相同或不同，并且选自NHR310，NR311R312，OR313，SR314和R315或R13 和R 14一起选自（a），（b）和（c），X是Cl，Br，I和用于制备式（3）化合物的方法，其包含式（ 1）作为关键中间体。

10. 发明申请

WO2015030585A2 METHODS FOR DETECTING POST-TRANSLATIONALLY MODIFIED LYSINES IN A POLYPEPTIDE 审中-公开
标题翻译：检测多肽中经翻译后修饰的蛋白质的方法
公开(公告)号：WO2015030585A2
公开(公告)日：2015-03-05
申请号：PCT/NL2014050581
申请日：2014-08-27
申请人： ACADEMISCH ZIEKENHUIS LEIDEN , MAX PLANCK GES ZUR FÖRDERUNG DER WISSENSCHAFTEN E V
发明人： VERTEGAAL ALFREDUS CORNELIS OTTO , HENDRIKS IVO ALEXANDER , MANN MATTHIAS
IPC分类号： G01N33/68
CPC分类号： G01N33/6842 , G01N2440/36 , G01N2500/04
摘要： The invention relates to methods for detecting a post-translationally modified lysines in a polypeptide. A specific type of post-translational lysine modification can be mapped at the level of the proteome. The invention further relates to a method for detecting whether a protein contains a proteinaceous post-translational modification.
摘要翻译：本发明涉及用于检测多肽中翻译后修饰的赖氨酸的方法。可以在蛋白质组的水平上映射特定类型的翻译后赖氨酸修饰。本发明还涉及一种用于检测蛋白质是否含有蛋白质翻译后修饰的方法。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式