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31. 发明授权

US4085272A 11-(2-Hydroxyethylthio)prostenoic acid E.sub.2 series derivatives 失效
标题翻译： 11-（2-羟乙硫基）前列腺酸E {HD 2 {B系列衍生物
公开(公告)号：US4085272A
公开(公告)日：1978-04-18
申请号：US782853
申请日：1977-03-30
申请人： Martin Joseph Weiss , Gerald Joseph Siuta
发明人： Martin Joseph Weiss , Gerald Joseph Siuta
IPC分类号： A61K31/557 , C07C29/09 , C07C29/10 , C07C29/40 , C07C29/42 , C07C29/62 , C07C31/133 , C07C35/06 , C07C35/17 , C07C45/00 , C07C45/41 , C07C45/45 , C07C49/293 , C07C405/00 , C07F7/08 , C07F7/18 , C07F7/22 , C07C177/00
CPC分类号： C07F7/2212 , A61K31/557 , C07C29/095 , C07C29/10 , C07C29/40 , C07C29/42 , C07C29/62 , C07C31/1336 , C07C35/06 , C07C35/17 , C07C405/0033 , C07F7/0812 , C07F7/0818 , C07F7/1852 , C07B2200/07 , C07B2200/09 , C07C2101/02 , C07C2101/04 , C07C2101/08 , C07C2101/14
摘要： This disclosure describes certain 11-(2-hydroxyethylthio)-9-keto-prostenoic acid E series derivatives, and their intermediates, useful as bronchodilators and inflammatory medeator release inhibitors.
摘要翻译：本公开描述了可用作支气管扩张剂和炎症介质释放抑制剂的某些11-（2-羟乙基硫代）-9-酮 - 前列腺酸E系列衍生物及其中间体。

32. 发明申请

US20050222274A1 Hyperforin halogenated derivatives, the use thereof and formulations containing them 失效
标题翻译： Hyperforin卤化衍生物，其使用和含有它们的制剂
公开(公告)号：US20050222274A1
公开(公告)日：2005-10-06
申请号：US10511894
申请日：2003-04-15
申请人： Ezio Bombardelli , Paolo Morazzoni , Antonella Riva , Nicola Fuzzati
发明人： Ezio Bombardelli , Paolo Morazzoni , Antonella Riva , Nicola Fuzzati
IPC分类号： A61K36/18 , A61K31/122 , A61P25/24 , A61P25/28 , C07C45/51 , C07C45/62 , C07C45/63 , C07C45/78 , C07C49/477 , C07C49/507 , C07C49/513 , C07C49/693 , C07C49/713 , C07C49/743 , C07C49/293 , A61K31/12
CPC分类号： C07C49/743 , C07C45/512 , C07C45/62 , C07C45/63 , C07C45/78 , C07C49/477 , C07C49/513 , C07C49/693 , C07C49/713
摘要： Hyperforin and adhyperforin halogenated derivatives of general formula (I) in which X, R and R1 have the meanings as defined in the disclosure, the process for the preparation thereof and the use thereof in the pharmaceutical and/or nutritional field, in particular in the treatment of depression, and Alzheimer's disease.
摘要翻译：其中X，R和R 1具有如本公开内容中所定义的含义的通式（I）的高效蛋白和高效皂化衍生物，其制备方法及其在药物和/ 或营养场，特别是治疗抑郁症和阿尔茨海默病。

33. 发明申请

US20050038112A1 Simplified sarcondictyn derivatives as anti-tumor agents 审中-公开
标题翻译：简化的sarcondictyn衍生物作为抗肿瘤剂
公开(公告)号：US20050038112A1
公开(公告)日：2005-02-17
申请号：US10489508
申请日：2002-09-06
申请人： Nicola Mongelli , Maria Menichincheri , Marina Ciomei , Cesare Gennari , Joachim Telser , Raphael Beumer
发明人： Nicola Mongelli , Maria Menichincheri , Marina Ciomei , Cesare Gennari , Joachim Telser , Raphael Beumer
IPC分类号： C07D233/58 , A61K31/122 , A61K31/215 , A61K31/22 , A61K31/351 , A61K31/4172 , A61K31/4178 , A61K31/421 , A61K31/426 , A61K31/4402 , A61K31/7056 , A61P35/00 , A61P35/02 , C07B61/00 , C07C67/29 , C07C69/013 , C07C69/16 , C07C69/28 , C07C69/618 , C07D213/55 , C07D233/54 , C07D233/90 , C07D263/32 , C07D263/34 , C07D277/20 , C07D277/24 , C07D277/30 , C07D309/10 , C07D405/12 , C07H15/26 , C07C69/74 , A61K31/12 , C07C49/293
CPC分类号： C07D263/34 , C07C69/013 , C07C69/618 , C07C2602/32 , C07D233/90 , C07D277/30
摘要： There are provided sarcodictyin derivatives or pharmaceutically acceptable salts thereof, which are characterized by a simplified chemical structure and have anti-tumor activity. A process for their preparation, the pharmaceutical compositions containing them, and their use in the prevention, control and treatment of cancer are also provided.
摘要翻译：提供了莽草苷衍生物或其药学上可接受的盐，其特征在于化学结构简单并具有抗肿瘤活性。还提供了其制备方法，含有它们的药物组合物及其在预防，控制和治疗癌症中的用途。

34. 发明授权

US6002046A Process for the preparation of cyclopropyl alkyl ketones 失效
标题翻译：制备环丙基烷基酮的方法
公开(公告)号：US6002046A
公开(公告)日：1999-12-14
申请号：US263876
申请日：1999-03-08
申请人： Manfred Kaufhold , Wolfgang Kleemiss , Udo Jegelka , Michael Korell
发明人： Manfred Kaufhold , Wolfgang Kleemiss , Udo Jegelka , Michael Korell
IPC分类号： C07B61/00 , C07C45/59 , C07C45/67 , C07C45/82 , C07C45/85 , C07C49/293 , C07C45/54
CPC分类号： C07C45/82 , C07C45/676 , C07C45/85
摘要： Cyclopropyl alkyl ketones are separated from 3-acyltetrahydrofuran-2-ones by adding an alcohol, water or a water/alcohol mixture to a reaction product containing C.sub.1-4 -alkyl cyclopropyl ketone and 4,5-dihydro-2-alkylfuran by-product and an acid catalyst and reacting the by-product with the added alcohol, water of water/alcohol mixture before, during or after distilling said reaction product; and effectively separating C.sub.1 -.sub.4 -alkyl cyclopropyl ketone from reaction by-products.In the preparation of cyclopropyl alkyl ketones from 3-acyltetrahydrofuran-2-ones very reactive 4,5-dihydro-2-alkylfurans are also produced. By reacting such compounds with nucleophilic compounds, such as alcohols or water, before, during or after distillation of the reaction products, it is possible reliably to separate off the 4,5-dihydro-2-alkylfurans as high-boiling addition compounds. The offgas which is produced in the production process for cyclopropyl alkyl ketones can be simply and reliably purified by reactive washing. The byproducts, which are difficult to handle for a production process, can thus be reliably eliminated.
摘要翻译：通过向含有C 1-4 - 烷基环丙基酮和4,5-二氢-2-烷基呋喃副产物的反应产物中加入醇，水或水/醇混合物将环丙基烷基酮与3-酰基四氢呋喃-2-酮分离和酸催化剂，在蒸馏所述反应产物之前，期间或之后使副产物与所加入的醇，水/醇混合物的水反应; 并有效地将C1-4烷基环丙基酮与反应副产物分离。在制备3-酰基四氢呋喃-2-酮的环丙基烷基酮时，也产生非常活泼的4,5-二氢-2-烷基呋喃。通过使这些化合物与亲核化合物如醇或水反应，在反应产物蒸馏之前，期间或之后，可以可靠地将4,5-二氢-2-烷基呋喃分离成高沸点加成化合物。在环丙基烷基酮的生产过程中生产的废气可以通过反应性洗涤简单可靠地纯化。因此，可以可靠地消除对生产过程难以处理的副产物。

35. 发明授权

US5079374A Fungicidal and plant growth-regulating hydroxyalkyl-azolyl derivatives 失效
标题翻译：杀菌剂和植物生长调节性羟基喹啉衍生物
公开(公告)号：US5079374A
公开(公告)日：1992-01-07
申请号：US464510
申请日：1990-01-12
申请人： Klaus Stroech , Monika Frie , Thomas Himmler , Wilhelm Brandes , Stefan Dutzmann , Gerd Hanssler
发明人： Klaus Stroech , Monika Frie , Thomas Himmler , Wilhelm Brandes , Stefan Dutzmann , Gerd Hanssler
IPC分类号： A01N31/04 , A01N31/14 , A01N43/32 , A01N43/50 , A01N43/653 , C07C33/50 , C07C45/62 , C07C45/74 , C07C49/163 , C07C49/225 , C07C49/237 , C07C49/293 , C07C49/327 , C07C49/457 , C07C49/467 , C07C49/533 , C07C49/563 , C07C49/567 , C07C49/657 , C07C49/687 , C07C49/693 , C07C49/753 , C07C317/24 , C07C323/22 , C07D20060101 , C07D233/60 , C07D233/61 , C07D249/08 , C07D303/08 , C07D303/22 , C07D303/34 , C07D319/16 , C07D319/18 , C07D319/20 , C07D405/06 , C07D407/06 , C07D521/00
CPC分类号： C07D303/22 , A01N43/653 , C07C321/00 , C07C33/50 , C07C45/62 , C07C45/74 , C07C49/457 , C07C49/467 , C07C49/567 , C07C49/657 , C07C49/687 , C07C49/693 , C07C49/753 , C07D231/12 , C07D233/56 , C07D249/08 , C07D303/08 , C07D303/34 , C07D407/06
摘要： Fungicidal and plant growth-regulating hydroxyalkyl-azolyl derivatives of the formula ##STR1## in which R represents hydrogen, alkyl or acyl,R.sup.1 represents halogen, optionally substituted phenyl or the grouping --z--R.sup.3, whereinz represents oxygen, sulphur, SO or SO.sub.2 andR.sup.3 represents optionally substituted alkyl, optionally substituted phenyl or optionally substituted phenylalkyl,R.sup.2 represents optionally substituted alkyl, optionally substituted cycloalkyl, optionally substituted naphthyl or the radical of the formula ##STR2## m represents the numbers 0, 1, 2 or 3, or R.sup.2 represents the radical or the formula ##STR3## X represents nitrogen or a CH group and Y represents the groupings --CH.sub.2 --CH.sub.2 --, --CH.dbd.CH--, --C.tbd.C--, ##STR4## and their addition products with acids and metal salts. Intermediates of the formulas ##STR5## are also new.

36. 发明授权

US4894464A Branched amides of L-aspartyl-D-amino acid dipeptides 失效
公开(公告)号：US4894464A
公开(公告)日：1990-01-16
申请号：US262627
申请日：1988-10-26
申请人： Thomas M. Brennan , Michael E. Hendrick
发明人： Thomas M. Brennan , Michael E. Hendrick
IPC分类号： A23L27/30 , C07C45/00 , C07C45/29 , C07C45/61 , C07C45/62 , C07C45/63 , C07C45/64 , C07C45/67 , C07C45/68 , C07C45/74 , C07C45/75 , C07C49/16 , C07C49/17 , C07C49/173 , C07C49/293 , C07C49/39 , C07C49/395 , C07C49/403 , C07C49/413 , C07C49/523 , C07C49/647 , C07C323/25 , C07D307/22 , C07D307/32 , C07D331/04 , C07D333/32 , C07D333/36 , C07D335/02 , C07K5/072
CPC分类号： C07D307/32 , A23L27/32 , C07C323/00 , C07C323/25 , C07C45/00 , C07C45/004 , C07C45/292 , C07C45/61 , C07C45/62 , C07C45/63 , C07C45/64 , C07C45/673 , C07C45/68 , C07C45/74 , C07C45/75 , C07C49/16 , C07C49/17 , C07C49/173 , C07C49/293 , C07C49/39 , C07C49/395 , C07C49/403 , C07C49/413 , C07C49/523 , C07C49/647 , C07D307/22 , C07D331/04 , C07D333/32 , C07D333/36 , C07D335/02 , C07K5/06113
摘要： Amides of L-aspartyl-D-amino acid dipeptides of the formula ##STR1## and physiologically acceptable cationic and acid addition salts thereof wherein R.sup.a is methyl, ethyl, n-propyl or isopropyl; R is a branched member selected from the group consisting of fenchyl, diisopropylcarbinyl, d-methyl-t-butylcarbinyl, d-ethyl-t-butylcarbinyl, di-t-butylcarbinyl, 2-methylthio-2,4-dimethylpentan-3-yl, ##STR2## where at least one of R.sup.3, R.sup.4, R.sup.5, R.sup.6 is alkyl having from one to four carbon atoms and the remainder are hydrogen or alkyl having from one to four carbon atoms, X is O, S, SO, SO.sub.2 C.dbd.O or CHOH; m is zero or 1-4, n and p are each zero, 1, 2 or 3 where the sum of n+p is not greater than 3 and the sum of the carbon atoms in R.sup.3, R.sup.4, R.sup.5 and R.sup.6 is not greater than six, and when both of R.sup.3 and R.sup.4 or R.sup.5 and R.sup.6 are alkyl they are methyl or ethyl, ##STR3## where one of R.sup.7, R.sup.8, R.sup.9 is alkyl having from one to four carbon atoms and the remainder are hydrogen or alkyl having from one to four carbon atoms and the sum of the carbon atoms in R.sup.7, R.sup.8 and R.sup.9 is not greater than six, m and q are the same or different and each have the values previously defined for m; ##STR4## where each of R.sup.12 and R.sup.13 are methyl or ethyl, or R.sup.12 is hydrogen and R.sup.13 is alkyl having from one to four carbon atoms, Z is O or NH and t is 1 or 2, ##STR5## where w is 1-4, R.sup.14 and R.sup.16 are each alkyl having from one to four carbon atoms, R.sup.15 is H, OH, methyl or ethyl and the sum of the carbon atoms in R.sup.14, R.sup.15 and R.sup.16 is not greater than six and when both of R.sup.14 and R.sup.15 are alkyl they are methyl or ethyl, and ##STR6## where R.sup.17 and R.sup.19 are alkyl having from one to four carbon atoms, R.sup.18 and R.sup.20 are H or alkyl having one to two carbon atoms, A is OH and B is H, OH or CH.sub.3 and taken together A and B are ##STR7## where the sum of the carbon atoms in R.sup.17, R.sup.18, R.sup.19 and R.sup.20 is not greater than six and when both of R.sup.17 and R.sup.18 or R.sup.19 and R.sup.20 are alkyl they are methyl or ethyl; said amides are potent sweeteners having advantages over the prior art, edible compositions containing them, methods for their use in edible compositions and novel amine and amide intermediates useful in their production.

37. 发明授权

US4742080A Therapeutic method for producing bronchodilation by administration of 15-deoxy-16-hydroxy prostaglandin esters 失效
标题翻译：通过施用15-脱氧-16-羟基前列腺素酯制备支气管扩张的治疗方法
公开(公告)号：US4742080A
公开(公告)日：1988-05-03
申请号：US712910
申请日：1985-03-15
申请人： Harold C. Kluender , Warren D. Woesner , William G. Biddlecom
发明人： Harold C. Kluender , Warren D. Woesner , William G. Biddlecom
IPC分类号： C07C29/09 , C07C29/147 , C07C29/36 , C07C29/42 , C07C29/62 , C07C45/30 , C07C45/45 , C07C45/62 , C07C47/293 , C07C47/30 , C07C49/293 , C07C49/433 , C07C49/443 , C07C51/09 , C07C51/353 , C07C51/38 , C07C61/04 , C07C61/08 , C07C405/00 , C07F1/08 , A61K31/215
CPC分类号： C07C29/147 , C07C29/095 , C07C29/36 , C07C29/42 , C07C29/62 , C07C405/00 , C07C405/0025 , C07C45/305 , C07C45/45 , C07C45/62 , C07C47/293 , C07C47/30 , C07C49/293 , C07C49/433 , C07C49/443 , C07C51/09 , C07C51/353 , C07C51/38 , C07C61/04 , C07C61/08 , C07F1/08 , C07C2101/04 , C07C2101/08 , C07C2101/14
摘要： A therapeutic method for producing bronchodilation in an individual for whom such therapy is indicated is disclosed. The method comprises administering to said individual an effective bronchodilation amount of certain derivatives of 15-deoxy-16-hydroxy-prostaglandin E.sub.1 esters.
摘要翻译：本发明公开了一种治疗方法。该方法包括向所述个体施用有效的支气管扩张剂量的15-脱氧-16-羟基 - 前列腺素E1酯的某些衍生物。

38. 发明授权

US4454328A Branched amides of L-aspartyl-D-amino acid dipeptides 失效
公开(公告)号：US4454328A
公开(公告)日：1984-06-12
申请号：US481495
申请日：1983-04-01
申请人： Thomas M. Brennan , Michael E. Hendrick
发明人： Thomas M. Brennan , Michael E. Hendrick
IPC分类号： A23L27/30 , C07C45/00 , C07C45/29 , C07C45/61 , C07C45/62 , C07C45/63 , C07C45/64 , C07C45/67 , C07C45/68 , C07C45/74 , C07C45/75 , C07C49/16 , C07C49/17 , C07C49/173 , C07C49/293 , C07C49/39 , C07C49/395 , C07C49/403 , C07C49/413 , C07C49/523 , C07C49/647 , C07D307/22 , C07D307/32 , C07D331/04 , C07D333/32 , C07D333/36 , C07D335/02 , C07D333/48
CPC分类号： C07D307/32 , A23L27/32 , C07C45/00 , C07C45/292 , C07C45/61 , C07C45/62 , C07C45/63 , C07C45/64 , C07C45/673 , C07C45/68 , C07C45/74 , C07C45/75 , C07C49/16 , C07C49/17 , C07C49/173 , C07C49/293 , C07C49/39 , C07C49/395 , C07C49/403 , C07C49/413 , C07C49/523 , C07C49/647 , C07D307/22 , C07D331/04 , C07D333/32 , C07D333/36 , C07D335/02
摘要： Amides of L-aspartyl-D-amino acid dipeptides of the formula ##STR1## and physiologically acceptable cationic and acid addition salts thereof wherein R.sup.a is CH.sub.2 OH or CH.sub.2 OCH.sub.3 ; R is a branched member selected from the group consisting of fenchyl, diisopropylcarbinyl, d-methyl-t-butylcarbinyl, d-ethyl-t-butylcarbinyl, di-t-butylcarbinyl, 2-methylthio-2,4-dimethylpentan-3-yl, ##STR2## where at least one of R.sup.3, R.sup.4, R.sup.5, R.sup.6 is alkyl having from one to four carbon atoms and the remainder are hydrogen or alkyl having from one to four carbon atoms, X is O, S, SO, SO.sub.2, C.dbd.O or CHOH; m is zero or 1-4, n and p are each zero, 1, 2 or 3 where the sum of n+p is not greater than 3 and the sum of the carbon atoms in R.sup.3, R.sup.4, R.sup.5 and R.sup.6 is not greater than six, and when both of R.sup.3 and R.sup.4 or R.sup.5 and R.sup.6 are alkyl they are methyl or ethyl, ##STR3## where one of R.sup.7, R.sup.8, R.sup.9 is alkyl having from one to four carbon atoms and the remainder are hydrogen or alkyl having from one to four carbon atoms and the sum of the carbon atoms in R.sup.7, R.sup.8 and R.sup.9 is not greater than six, m and q are the same or different and each have the values previously defined for m; ##STR4## where each of R.sup.12 and R.sup.13 are methyl or ethyl, or R.sup.12 is hydrogen and R.sup.13 is alkyl having from one to four carbon atoms, Z is O or NH and t is 1 or 2, ##STR5## where W is 1-4, R.sup.14 and R.sup.16 are each alkyl having from one to four carbon atoms, R.sup.15 is H, OH, methyl or ethyl and the sum of the carbon atoms in R.sup.14, R.sup.15 and R.sup.16 is not greater than six and when both of R.sup.14 and R.sup.15 are alkyl they are methyl or ethyl, and ##STR6## where R.sup.17 and R.sup.19 are alkyl having from one to four carbon atoms, R.sup.18 and R.sup.20 are H or alkyl having one to two carbon atoms, A is OH and B is H, OH or CH.sub.3 and taken together A and B are ##STR7## where the sum of the carbon atoms in R.sup.17, R.sup.18, R.sup.19 and R.sup.20 is not greater than six and when both of R.sup.17 and R.sup.18 or R.sup.19 and R.sup.20 are alkyl they are methyl or ethyl;said amides are potent sweeteners having advantages over the prior art, edible compositions containing them, methods for their use in edible compositions and novel amide intermediates useful in their production.

39. 发明授权

US4411925A Branched amides of L-aspartyl-d-amino acid dipeptides 失效
标题翻译： L-天冬氨酰基-d-氨基酸二肽的分支酰胺
公开(公告)号：US4411925A
公开(公告)日：1983-10-25
申请号：US201745
申请日：1980-11-05
申请人： Thomas M. Brennan , Michael E. Hendrick
发明人： Thomas M. Brennan , Michael E. Hendrick
IPC分类号： A23L27/30 , C07C45/00 , C07C45/29 , C07C45/61 , C07C45/62 , C07C45/63 , C07C45/64 , C07C45/67 , C07C45/68 , C07C45/74 , C07C45/75 , C07C49/16 , C07C49/17 , C07C49/173 , C07C49/293 , C07C49/39 , C07C49/395 , C07C49/403 , C07C49/413 , C07C49/523 , C07C49/647 , C07C323/25 , C07D307/22 , C07D307/32 , C07D331/02 , C07D331/04 , C07D333/32 , C07D333/36 , C07D335/02 , C07K5/072 , C07K5/075 , A23L1/236
CPC分类号： C07D307/32 , A23L27/32 , C07C323/00 , C07C323/25 , C07C45/00 , C07C45/004 , C07C45/292 , C07C45/61 , C07C45/62 , C07C45/63 , C07C45/64 , C07C45/673 , C07C45/68 , C07C45/74 , C07C45/75 , C07C49/16 , C07C49/17 , C07C49/173 , C07C49/293 , C07C49/39 , C07C49/395 , C07C49/403 , C07C49/413 , C07C49/523 , C07C49/647 , C07D307/22 , C07D331/04 , C07D333/32 , C07D333/36 , C07D335/02 , C07K5/06113 , Y10S426/804 , Y10S530/801
摘要： Amides of L-aspartyl-D-amino acid dipeptides of the formula ##STR1## and physiologically acceptable cationic and acid addition salts thereof wherein R.sup.a is methyl, ethyl, n-propyl or isopropyl; R is a branched member selected from the group consisting of fenchyl, diisopropylcarbinyl, d-methyl-t-butylcarbinyl, d-ethyl-t-butylcarbinyl, di-t-butylcarbinyl, 2-methylthio-2,4-dimethylpentan-3-yl, ##STR2## said amides are potent sweeteners having advantages over the prior art, edible compositions containing them, methods for their use in edible compositions and novel amine and amide intermediates useful in their production.
摘要翻译：式（I）的L-天冬氨酰-D-氨基酸二肽和其生理上可接受的阳离子和酸加成盐的酰胺，其中R a是甲基，乙基，正丙基或异丙基; R是选自偕基，二异丙基甲脒基，二甲基 - 叔丁基咔inyl基，二乙基 - 叔丁基咔inyl基，二 - 叔丁基咔inyl基，2-甲硫基-2,4-二甲基戊-3-基所述酰胺是具有优于现有技术的有用甜味剂，含有它们的食用组合物，它们在可食用组合物中的用途及其生产中可用的新型胺和酰胺中间体。

40. 发明授权

US4165331A 11-(2-Hydroxyethylthio)prostenoic acid E series derivatives 失效
标题翻译： 11-（2-羟乙硫基）前列腺酸E系列衍生物
公开(公告)号：US4165331A
公开(公告)日：1979-08-21
申请号：US842843
申请日：1977-10-17
申请人： Martin J. Weiss , Gerald J. Siuta
发明人： Martin J. Weiss , Gerald J. Siuta
IPC分类号： C07C29/09 , C07C29/10 , C07C29/40 , C07C29/42 , C07C29/62 , C07C31/133 , C07C35/06 , C07C45/45 , C07C49/293 , C07C405/00 , C07F7/08 , C07F7/18 , C07F7/22
CPC分类号： C07F7/2212 , C07C29/095 , C07C29/10 , C07C29/40 , C07C29/42 , C07C29/62 , C07C31/1336 , C07C35/06 , C07C405/0033 , C07F7/0818 , C07F7/1804 , C07B2200/07 , C07B2200/09 , C07C2101/04 , C07C2101/08 , C07C2101/14
摘要： This disclosure describes certain 11-(2-hydroxyethylthio)-9-keto-prostenoic acid E series derivatives, and their intermediates, useful as bronchodilators and inflammatory medeator release inhibitors.
摘要翻译：本公开描述了可用作支气管扩张剂和炎症介质释放抑制剂的某些11-（2-羟乙基硫代）-9-酮 - 前列腺酸E系列衍生物及其中间体。

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