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1. 发明授权

US4804782A Branched amides of L-aspartyl-D-amino acid dipeptides 失效
公开(公告)号：US4804782A
公开(公告)日：1989-02-14
申请号：US796173
申请日：1985-11-08
申请人： Thomas M. Brennan , Michael E. Hendrick
发明人： Thomas M. Brennan , Michael E. Hendrick
IPC分类号： A23L27/30 , C07C45/00 , C07C45/29 , C07C45/61 , C07C45/63 , C07C45/64 , C07C45/68 , C07C45/75 , C07C233/00 , C07C323/25 , C07D307/22 , C07D307/32 , C07D331/04 , C07D333/32 , C07D333/36 , C07D335/02 , C07K5/072 , C07C103/37 , A23L1/236 , C07C103/52
CPC分类号： C07D307/32 , A23L27/32 , C07C323/00 , C07C323/25 , C07C45/004 , C07C45/292 , C07C45/61 , C07C45/63 , C07C45/64 , C07C45/68 , C07C45/75 , C07D307/22 , C07D331/04 , C07D333/32 , C07D333/36 , C07D335/02 , C07K5/06113
摘要： Amides of L-aspartyl-D-amino acid dipeptides of the formula ##STR1## and physiologically acceptable cationic and acid addition salts thereof wherein R.sup.a is methyl, ethyl, n-propyl or isopropyl; R is a branched member selected from the group consisting of fenchyl, diisopropylcarbinyl, d-methyl-t-butylcarbinyl, d-ethyl-t-butylcarbinyl, di-t-butylcarbinyl, 2-methylthio-2,4-dimethylpentan-3-yl, ##STR2## where at least one of R.sup.3, R.sup.4, R.sup.5, R.sup.6 is alkyl having from one to four carbon atoms and the remainder are hydrogen or alkyl having from one to four carbon atoms, X is O, S, SO, SO.sub.2, C.dbd.O or CHOH; m is zero or 1-4, n and p are each zero, 1, 2 or 3 where the sum of n+p is not greater than 3 and the sum of the carbon atoms in R.sup.3, R.sup.4, R.sup.5 and R.sup.6 is not greater than six, and when both of R.sup.3 and R.sup.4 or R.sup.5 and R.sup.6 are alkyl they are methyl or ethyl, ##STR3## where one of R.sup.7, R.sup.8, R.sup.9 is alkyl having from one to four carbon atoms and the remainder are hydrogen or alkyl having from one to four carbon atoms and the sum of the carbon atoms in R.sup.7, R.sup.8 and R.sup.9 is not greater than six, m and q are the same or different and each have the values previously defined for m; ##STR4## where each of R.sup.12 and R.sup.13 are methyl or ethyl, or R.sup.12 is hydrogen and R.sup.13 is alkyl having from one to four carbon atoms, Z is O or NH and t is 1 or 2, ##STR5## where w is 1-4, R.sup.14 and R.sup.16 are each alkyl having from one to four carbon atoms, R.sup.15 is H, OH, methyl or ethyl and the sum of the carbon atoms in R.sup.14, R.sup.15 and R.sup.16 is not greater than six and when both of R.sup.14 and R.sup.15 are alkyl they are methyl or ethyl, and where R.sup.17 and R.sup.19 are alkyl having from one to four carbon atoms, R.sup.18 and R.sup.20 are H or alkyl having one to two carbon atoms, A is OH and B is H, OH or CH.sub.3 and taken together A and B are ##STR6## where the sum of the carbon atoms in R.sup.17, R.sup.18, R.sup.19 and R.sup.20 is not greater than six and when both of R.sup.17 and R.sup.18 or R.sup.19 and R.sup.20 are alkyl they are methyl or ethyl;said amides are potent sweetners having advantages over the prior art, edible compositions containing them, methods for their use in edible compositions and novel amine and amide intermediates useful in their production.

2. 发明授权

US4894464A Branched amides of L-aspartyl-D-amino acid dipeptides 失效
公开(公告)号：US4894464A
公开(公告)日：1990-01-16
申请号：US262627
申请日：1988-10-26
申请人： Thomas M. Brennan , Michael E. Hendrick
发明人： Thomas M. Brennan , Michael E. Hendrick
IPC分类号： A23L27/30 , C07C45/00 , C07C45/29 , C07C45/61 , C07C45/62 , C07C45/63 , C07C45/64 , C07C45/67 , C07C45/68 , C07C45/74 , C07C45/75 , C07C49/16 , C07C49/17 , C07C49/173 , C07C49/293 , C07C49/39 , C07C49/395 , C07C49/403 , C07C49/413 , C07C49/523 , C07C49/647 , C07C323/25 , C07D307/22 , C07D307/32 , C07D331/04 , C07D333/32 , C07D333/36 , C07D335/02 , C07K5/072
CPC分类号： C07D307/32 , A23L27/32 , C07C323/00 , C07C323/25 , C07C45/00 , C07C45/004 , C07C45/292 , C07C45/61 , C07C45/62 , C07C45/63 , C07C45/64 , C07C45/673 , C07C45/68 , C07C45/74 , C07C45/75 , C07C49/16 , C07C49/17 , C07C49/173 , C07C49/293 , C07C49/39 , C07C49/395 , C07C49/403 , C07C49/413 , C07C49/523 , C07C49/647 , C07D307/22 , C07D331/04 , C07D333/32 , C07D333/36 , C07D335/02 , C07K5/06113
摘要： Amides of L-aspartyl-D-amino acid dipeptides of the formula ##STR1## and physiologically acceptable cationic and acid addition salts thereof wherein R.sup.a is methyl, ethyl, n-propyl or isopropyl; R is a branched member selected from the group consisting of fenchyl, diisopropylcarbinyl, d-methyl-t-butylcarbinyl, d-ethyl-t-butylcarbinyl, di-t-butylcarbinyl, 2-methylthio-2,4-dimethylpentan-3-yl, ##STR2## where at least one of R.sup.3, R.sup.4, R.sup.5, R.sup.6 is alkyl having from one to four carbon atoms and the remainder are hydrogen or alkyl having from one to four carbon atoms, X is O, S, SO, SO.sub.2 C.dbd.O or CHOH; m is zero or 1-4, n and p are each zero, 1, 2 or 3 where the sum of n+p is not greater than 3 and the sum of the carbon atoms in R.sup.3, R.sup.4, R.sup.5 and R.sup.6 is not greater than six, and when both of R.sup.3 and R.sup.4 or R.sup.5 and R.sup.6 are alkyl they are methyl or ethyl, ##STR3## where one of R.sup.7, R.sup.8, R.sup.9 is alkyl having from one to four carbon atoms and the remainder are hydrogen or alkyl having from one to four carbon atoms and the sum of the carbon atoms in R.sup.7, R.sup.8 and R.sup.9 is not greater than six, m and q are the same or different and each have the values previously defined for m; ##STR4## where each of R.sup.12 and R.sup.13 are methyl or ethyl, or R.sup.12 is hydrogen and R.sup.13 is alkyl having from one to four carbon atoms, Z is O or NH and t is 1 or 2, ##STR5## where w is 1-4, R.sup.14 and R.sup.16 are each alkyl having from one to four carbon atoms, R.sup.15 is H, OH, methyl or ethyl and the sum of the carbon atoms in R.sup.14, R.sup.15 and R.sup.16 is not greater than six and when both of R.sup.14 and R.sup.15 are alkyl they are methyl or ethyl, and ##STR6## where R.sup.17 and R.sup.19 are alkyl having from one to four carbon atoms, R.sup.18 and R.sup.20 are H or alkyl having one to two carbon atoms, A is OH and B is H, OH or CH.sub.3 and taken together A and B are ##STR7## where the sum of the carbon atoms in R.sup.17, R.sup.18, R.sup.19 and R.sup.20 is not greater than six and when both of R.sup.17 and R.sup.18 or R.sup.19 and R.sup.20 are alkyl they are methyl or ethyl; said amides are potent sweeteners having advantages over the prior art, edible compositions containing them, methods for their use in edible compositions and novel amine and amide intermediates useful in their production.

3. 发明授权

US4855454A Branched amides of L-aspartyl-D-amino acid dipeptides 失效
公开(公告)号：US4855454A
公开(公告)日：1989-08-08
申请号：US218245
申请日：1988-07-13
申请人： Thomas M. Brennan , Michael E. Hendrick
发明人： Thomas M. Brennan , Michael E. Hendrick
IPC分类号： A23L27/30 , C07C45/00 , C07C45/29 , C07C45/61 , C07C45/63 , C07C45/64 , C07C45/68 , C07C45/75 , C07C323/25 , C07D307/22 , C07D307/32 , C07D331/04 , C07D333/32 , C07D333/36 , C07D335/02 , C07K5/072
CPC分类号： C07D307/32 , A23L27/32 , C07C323/00 , C07C323/25 , C07C45/004 , C07C45/292 , C07C45/61 , C07C45/63 , C07C45/64 , C07C45/68 , C07C45/75 , C07D307/22 , C07D331/04 , C07D333/32 , C07D333/36 , C07D335/02 , C07K5/06113
摘要： Amides of L-aspartyl-D-amino acid dipeptides of the formula ##STR1## and physiologically acceptable cationic and acid addition salts thereof wherein R.sup.a is methyl, ethyl, n-propyl or isopropyl; R is a branched member selected from the group consisting of fenchyl, diisopropylcarbinyl, d-methyl-t-butylcarbinyl, d-ethyl-t-butylcarbinyl, di-t-butylcarbinyl, 2-methylthio-2,4-dimethylpentan-3-yl, ##STR2## where at least one of R.sup.3, R.sup.4, R.sup.5, R.sup.6 is alkyl having from one to four carbon atoms and the remainder are hydrogen or alkyl having from one to four carbon atoms, X is O, S, SO, SO.sub.2, C.dbd.O or CHOH; m is zero or 1-4, n and p are each zero, 1, 2 or 3 where the sum of n+p is not greater than 3 and the sum of the carbon atoms in R.sup.3, R.sup.4, R.sup.5 and R.sup.6 is not greater than six, and when both of R.sup.3 and R.sup.4 or R.sup.5 and R.sup.6 are alkyl they are methyl or ethyl, ##STR3## where one of R.sup.7, R.sup.8, R.sup.9 is alkyl having from one to four carbon atoms and the remainder are hydrogen or alkyl having from one to four carbon atoms and the sum of the carbon atoms in R.sup.7, R.sup.8 and R.sup.9 is not greater than six, m and q are the same or different and each have the values previously defined for m; ##STR4## where each of R.sup.12 and R.sup.13 are methyl or ethyl, or R.sup.12 is hydrogen and R.sup.13 is alkyl having from one to four carbon atoms, Z is O or NH and t is 1 or 2, ##STR5## where w is 1-4, R.sup.14 and R.sup.16 are each alkyl having from one to four carbon atoms, R.sup.15 is H, OH, methyl or ethyl and the sum of the carbon atoms in R.sup.14, R.sup.15 and R.sup.16 is not greater than six and when both of R.sup.14 and R.sup.15 are alkyl they are methyl or ethyl, and ##STR6## where R.sup.17 and R.sup.19 are alkyl having from one to four carbon atoms, R.sup.18 and R.sup.20 are H or alkyl having one to two carbon atoms, A is OH and B is H, OH or CH.sub.3 and taken together A and B are ##STR7## where the sum of the carbon atoms in R.sup.17, R.sup.18, R.sup.19 and R.sup.20 is not greater than six and when both of R.sup.17 and R.sup.18 or R.sup.19 and R.sup.20 are alkyl they are methyl or ethyl; said amides are potent sweetners having advantages over the prior art, edible compositions containing them, methods for their use in edible compositions and novel amine and amide intermediates useful in their production.

4. 发明授权

US4454328A Branched amides of L-aspartyl-D-amino acid dipeptides 失效
公开(公告)号：US4454328A
公开(公告)日：1984-06-12
申请号：US481495
申请日：1983-04-01
申请人： Thomas M. Brennan , Michael E. Hendrick
发明人： Thomas M. Brennan , Michael E. Hendrick
IPC分类号： A23L27/30 , C07C45/00 , C07C45/29 , C07C45/61 , C07C45/62 , C07C45/63 , C07C45/64 , C07C45/67 , C07C45/68 , C07C45/74 , C07C45/75 , C07C49/16 , C07C49/17 , C07C49/173 , C07C49/293 , C07C49/39 , C07C49/395 , C07C49/403 , C07C49/413 , C07C49/523 , C07C49/647 , C07D307/22 , C07D307/32 , C07D331/04 , C07D333/32 , C07D333/36 , C07D335/02 , C07D333/48
CPC分类号： C07D307/32 , A23L27/32 , C07C45/00 , C07C45/292 , C07C45/61 , C07C45/62 , C07C45/63 , C07C45/64 , C07C45/673 , C07C45/68 , C07C45/74 , C07C45/75 , C07C49/16 , C07C49/17 , C07C49/173 , C07C49/293 , C07C49/39 , C07C49/395 , C07C49/403 , C07C49/413 , C07C49/523 , C07C49/647 , C07D307/22 , C07D331/04 , C07D333/32 , C07D333/36 , C07D335/02
摘要： Amides of L-aspartyl-D-amino acid dipeptides of the formula ##STR1## and physiologically acceptable cationic and acid addition salts thereof wherein R.sup.a is CH.sub.2 OH or CH.sub.2 OCH.sub.3 ; R is a branched member selected from the group consisting of fenchyl, diisopropylcarbinyl, d-methyl-t-butylcarbinyl, d-ethyl-t-butylcarbinyl, di-t-butylcarbinyl, 2-methylthio-2,4-dimethylpentan-3-yl, ##STR2## where at least one of R.sup.3, R.sup.4, R.sup.5, R.sup.6 is alkyl having from one to four carbon atoms and the remainder are hydrogen or alkyl having from one to four carbon atoms, X is O, S, SO, SO.sub.2, C.dbd.O or CHOH; m is zero or 1-4, n and p are each zero, 1, 2 or 3 where the sum of n+p is not greater than 3 and the sum of the carbon atoms in R.sup.3, R.sup.4, R.sup.5 and R.sup.6 is not greater than six, and when both of R.sup.3 and R.sup.4 or R.sup.5 and R.sup.6 are alkyl they are methyl or ethyl, ##STR3## where one of R.sup.7, R.sup.8, R.sup.9 is alkyl having from one to four carbon atoms and the remainder are hydrogen or alkyl having from one to four carbon atoms and the sum of the carbon atoms in R.sup.7, R.sup.8 and R.sup.9 is not greater than six, m and q are the same or different and each have the values previously defined for m; ##STR4## where each of R.sup.12 and R.sup.13 are methyl or ethyl, or R.sup.12 is hydrogen and R.sup.13 is alkyl having from one to four carbon atoms, Z is O or NH and t is 1 or 2, ##STR5## where W is 1-4, R.sup.14 and R.sup.16 are each alkyl having from one to four carbon atoms, R.sup.15 is H, OH, methyl or ethyl and the sum of the carbon atoms in R.sup.14, R.sup.15 and R.sup.16 is not greater than six and when both of R.sup.14 and R.sup.15 are alkyl they are methyl or ethyl, and ##STR6## where R.sup.17 and R.sup.19 are alkyl having from one to four carbon atoms, R.sup.18 and R.sup.20 are H or alkyl having one to two carbon atoms, A is OH and B is H, OH or CH.sub.3 and taken together A and B are ##STR7## where the sum of the carbon atoms in R.sup.17, R.sup.18, R.sup.19 and R.sup.20 is not greater than six and when both of R.sup.17 and R.sup.18 or R.sup.19 and R.sup.20 are alkyl they are methyl or ethyl;said amides are potent sweeteners having advantages over the prior art, edible compositions containing them, methods for their use in edible compositions and novel amide intermediates useful in their production.

5. 发明授权

US4411925A Branched amides of L-aspartyl-d-amino acid dipeptides 失效
标题翻译： L-天冬氨酰基-d-氨基酸二肽的分支酰胺
公开(公告)号：US4411925A
公开(公告)日：1983-10-25
申请号：US201745
申请日：1980-11-05
申请人： Thomas M. Brennan , Michael E. Hendrick
发明人： Thomas M. Brennan , Michael E. Hendrick
IPC分类号： A23L27/30 , C07C45/00 , C07C45/29 , C07C45/61 , C07C45/62 , C07C45/63 , C07C45/64 , C07C45/67 , C07C45/68 , C07C45/74 , C07C45/75 , C07C49/16 , C07C49/17 , C07C49/173 , C07C49/293 , C07C49/39 , C07C49/395 , C07C49/403 , C07C49/413 , C07C49/523 , C07C49/647 , C07C323/25 , C07D307/22 , C07D307/32 , C07D331/02 , C07D331/04 , C07D333/32 , C07D333/36 , C07D335/02 , C07K5/072 , C07K5/075 , A23L1/236
CPC分类号： C07D307/32 , A23L27/32 , C07C323/00 , C07C323/25 , C07C45/00 , C07C45/004 , C07C45/292 , C07C45/61 , C07C45/62 , C07C45/63 , C07C45/64 , C07C45/673 , C07C45/68 , C07C45/74 , C07C45/75 , C07C49/16 , C07C49/17 , C07C49/173 , C07C49/293 , C07C49/39 , C07C49/395 , C07C49/403 , C07C49/413 , C07C49/523 , C07C49/647 , C07D307/22 , C07D331/04 , C07D333/32 , C07D333/36 , C07D335/02 , C07K5/06113 , Y10S426/804 , Y10S530/801
摘要： Amides of L-aspartyl-D-amino acid dipeptides of the formula ##STR1## and physiologically acceptable cationic and acid addition salts thereof wherein R.sup.a is methyl, ethyl, n-propyl or isopropyl; R is a branched member selected from the group consisting of fenchyl, diisopropylcarbinyl, d-methyl-t-butylcarbinyl, d-ethyl-t-butylcarbinyl, di-t-butylcarbinyl, 2-methylthio-2,4-dimethylpentan-3-yl, ##STR2## said amides are potent sweeteners having advantages over the prior art, edible compositions containing them, methods for their use in edible compositions and novel amine and amide intermediates useful in their production.
摘要翻译：式（I）的L-天冬氨酰-D-氨基酸二肽和其生理上可接受的阳离子和酸加成盐的酰胺，其中R a是甲基，乙基，正丙基或异丙基; R是选自偕基，二异丙基甲脒基，二甲基 - 叔丁基咔inyl基，二乙基 - 叔丁基咔inyl基，二 - 叔丁基咔inyl基，2-甲硫基-2,4-二甲基戊-3-基所述酰胺是具有优于现有技术的有用甜味剂，含有它们的食用组合物，它们在可食用组合物中的用途及其生产中可用的新型胺和酰胺中间体。

6. 发明授权

US5356644A Low calorie fat substitute 失效
标题翻译：低热量脂肪替代品
公开(公告)号：US5356644A
公开(公告)日：1994-10-18
申请号：US957648
申请日：1992-10-06
申请人： Michael E. Hendrick , Robert A. Reimer
发明人： Michael E. Hendrick , Robert A. Reimer
IPC分类号： A23D9/05 , A23L1/00 , A23L1/24 , A23L1/308 , A23L1/307
CPC分类号： A23D9/05 , A23L27/60 , A23L33/21 , A23L33/26 , A23P10/35 , Y10S426/804
摘要： There is disclosed a low calorie fat substitute comprising an outer coating of a digestible fat surrounding an inner core of a low caloric or non-caloric material.
摘要翻译：公开了一种低热量脂肪替代物，其包括围绕低热量或非热量材料的内核的可消化脂肪的外涂层。

7. 发明授权

US4870190A Branched amides of L-aspartyl-D-amino acid dipeptides 失效
标题翻译： L-天冬氨酰-D-氨基酸二肽的分支酰胺
公开(公告)号：US4870190A
公开(公告)日：1989-09-26
申请号：US256588
申请日：1988-10-12
申请人： Thomas M. Brennan , Michael E. Hendrick
发明人： Thomas M. Brennan , Michael E. Hendrick
IPC分类号： A23L27/30 , C07C45/00 , C07C45/29 , C07C45/61 , C07C45/63 , C07C45/64 , C07C45/68 , C07C45/75 , C07C323/25 , C07D307/22 , C07D307/32 , C07D331/04 , C07D333/32 , C07D333/36 , C07D335/02 , C07D339/02 , C07K5/072
CPC分类号： C07D307/32 , A23L27/32 , C07C323/00 , C07C323/25 , C07C45/004 , C07C45/292 , C07C45/61 , C07C45/63 , C07C45/64 , C07C45/68 , C07C45/75 , C07D307/22 , C07D331/04 , C07D333/32 , C07D333/36 , C07D335/02 , C07K5/06113
摘要： Amides of L-aspartyl-D-amino acid dipeptides of the formula ##STR1## and physiologically acceptable cationic and acid addition salts thereof wherein R.sup.a is methyl, hydroxymethyl, ethyl, n-propyl or isopropyl; R is ##STR2## where at least one of R.sup.3, R.sup.4, R.sup.5, R.sup.6 is alkyl having from one to four carbon atoms and the remainder are hydrogen or alkyl having from one to four carbon atoms, and the sum of the carbon atoms in R.sup.3, R.sup.4, R.sup.5 and R.sup.6 is not greater than six; and when both of R.sup.3 and R.sup.4 or R.sup.5 and R.sup.6 are alkyl, they are methyl or ethyl.Said amides are potent sweeteners having advantages over the prior art, edible compositions containing them, methods for their use in edible compositions and novel amine and amide intermediates useful in their production.
摘要翻译：式（I）的L-天冬氨酰-D-氨基酸二肽和其生理上可接受的阳离子和酸加成盐的酰胺，其中R a是甲基，羟甲基，乙基，正丙基或异丙基; R是R 3，R 4，R 5，R 6中的至少一个是具有1-4个碳原子的烷基，其余是氢或具有1-4个碳原子的烷基，R3中的碳原子之和，R4，R5和R6不大于6; 当R3和R4或R5和R6都是烷基时，它们是甲基或乙基。所述酰胺是具有优于现有技术的有益甜味剂，含有它们的食用组合物，它们在可食用组合物中的用途及其可用于其生产的新型胺和酰胺中间体。

8. 发明授权

US4797298A Branched amides of L-aspartyl-D-amino acid dipeptides 失效
标题翻译： L-天冬氨酰-D-氨基酸二肽的分支酰胺
公开(公告)号：US4797298A
公开(公告)日：1989-01-10
申请号：US944269
申请日：1986-12-18
申请人： Thomas M. Brennan , Michael E. Hendrick
发明人： Thomas M. Brennan , Michael E. Hendrick
IPC分类号： A23L27/30 , C07C45/00 , C07C45/29 , C07C45/61 , C07C45/63 , C07C45/64 , C07C45/68 , C07C45/75 , C07C323/25 , C07D307/22 , C07D307/32 , C07D331/04 , C07D333/32 , C07D333/36 , C07D335/02 , C07D339/04 , C07K5/072 , C07K5/075 , C07D339/02 , A23L1/236
CPC分类号： C07D307/32 , A23L27/32 , C07C323/00 , C07C323/25 , C07C45/004 , C07C45/292 , C07C45/61 , C07C45/63 , C07C45/64 , C07C45/68 , C07C45/75 , C07D307/22 , C07D331/04 , C07D333/32 , C07D333/36 , C07D335/02 , C07K5/06113
摘要： Amides of L-aspartyl-D-amino acid dipeptides of the formula ##STR1## and physiologically acceptable cationic and acid addition salts thereof wherein R.sup.a is methyl, hydroxymethyl, ethyl, n-propyl or isopropyl; R is ##STR2## where at least one of R.sup.3, R.sup.4, R.sup.5, R.sup.6 is alkyl having from one to four carbon atoms and the remainder are hydrogen or alkyl having from one to four carbon atoms, and the sum of the carbon atoms in R.sup.3, R.sup.4, R.sup.5 and R.sup.6 is not greater than six; and when both of R.sup.3 and R.sup.4 or R.sup.5 and R.sup.6 are alkyl, they are methyl or ethyl.Said amides are potent sweeteners having advantages over the prior art, edible compositions containing them, methods for their use in edible compositions and novel amine and amide intermediates useful in their production.
摘要翻译：式（I）的L-天冬氨酰-D-氨基酸二肽和其生理上可接受的阳离子和酸加成盐的酰胺，其中R a是甲基，羟甲基，乙基，正丙基或异丙基; R是R 3，R 4，R 5，R 6中的至少一个是具有1-4个碳原子的烷基，其余是氢或具有1-4个碳原子的烷基，R3中的碳原子之和，R4，R5和R6不大于6; 当R3和R4或R5和R6都是烷基时，它们是甲基或乙基。所述酰胺是具有优于现有技术的有益甜味剂，含有它们的食用组合物，它们在可食用组合物中的用途及其可用于其生产的新型胺和酰胺中间体。

9. 发明授权

US5681601A Low calorie fat substitute 失效
标题翻译：低热量脂肪替代品
公开(公告)号：US5681601A
公开(公告)日：1997-10-28
申请号：US637463
申请日：1996-04-25
申请人： Michael E. Hendrick , Robert A. Reimer
发明人： Michael E. Hendrick , Robert A. Reimer
IPC分类号： A23G3/00 , A21D13/08 , A23D9/007 , A23D9/05 , A23G3/34 , A23L1/00 , A23L1/164 , A23L1/24 , A23L1/307 , A23L1/308 , C08B37/00
CPC分类号： A23D9/05 , A23L27/60 , A23L33/21 , A23L33/26 , A23P10/35 , Y10S426/804
摘要： There is disclosed a low calorie fat substitute comprising an outer coating of a digestible fat surrounding an inner core of a low caloric or non-caloric material.
摘要翻译：公开了一种低热量脂肪替代物，其包括围绕低热量或非热量材料的内核的可消化脂肪的外涂层。

10. 发明授权

US4399163A Branched amides of L-aspartyl-D-amino acid dipeptides 失效
标题翻译： L-天冬氨酰-D-氨基酸二肽的分支酰胺
公开(公告)号：US4399163A
公开(公告)日：1983-08-16
申请号：US276243
申请日：1981-06-26
申请人： Thomas M. Brennan , Michael E. Hendrick
发明人： Thomas M. Brennan , Michael E. Hendrick
IPC分类号： A23L27/30 , C07C45/00 , C07C45/29 , C07C45/61 , C07C45/62 , C07C45/63 , C07C45/64 , C07C45/67 , C07C45/68 , C07C45/74 , C07C49/16 , C07C49/17 , C07C49/173 , C07C49/293 , C07C49/39 , C07C49/395 , C07C49/403 , C07C49/413 , C07C49/523 , C07C49/647 , C07C323/25 , C07D307/22 , C07D307/32 , C07D331/04 , C07D333/32 , C07D333/36 , C07D335/02 , C07K5/072 , C07K5/075 , A23L1/236
CPC分类号： C07D307/32 , A23L27/32 , C07C323/25 , C07C45/00 , C07C45/004 , C07C45/292 , C07C45/61 , C07C45/62 , C07C45/63 , C07C45/64 , C07C45/673 , C07C45/68 , C07C45/74 , C07C49/16 , C07C49/17 , C07C49/173 , C07C49/293 , C07C49/39 , C07C49/395 , C07C49/403 , C07C49/413 , C07C49/523 , C07C49/647 , C07D307/22 , C07D331/04 , C07D333/32 , C07D333/36 , C07D335/02 , C07K5/06113 , Y10S426/804 , Y10S530/801
摘要： Amides of L-aspartyl-D-amino acid dipeptides of the formula ##STR1## and physiologically acceptable cationic and acid addition salts thereof wherein R.sup.a is CH.sub.2 OH or CH.sub.2 OCH.sub.3 ; R is a branched member selected from the group consisting of fenchyl, diisopropylcarbinyl, d-methyl-t-butylcarbinyl, d-ethyl-t-butylcarbinyl, di-t-butyl-carbinyl, 2-methylthio-2,4-dimethylpentan-3-yl, ##STR2## said amides are potent sweeteners having advantages over the prior art, edible compositions containing them, methods for their use in edible compositions and novel amide intermediates useful in their production.
摘要翻译：式（I）的L-天冬氨酰-D-氨基酸二肽和其生理上可接受的阳离子和酸加成盐的酰胺，其中R a是CH 2 OH或CH 2 OCH 3; R是选自偕基，二异丙基脒基，二甲基 - 叔丁基carb基，二乙基 - 叔丁基咔inyl基，二 - 叔丁基 - 碳酰基，2-甲硫基-2,4-二甲基戊烷-3 所述酰胺是具有优于现有技术的有用甜味剂，含有它们的食用组合物，它们在食用组合物中的用途及其生产中可用的新型酰胺中间体。

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