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1. 发明申请

WO2019133187A1 MOBILE SMART DEVICE WITH INTEGRATED DAWN SIMULATION 审中-公开
公开(公告)号：WO2019133187A1
公开(公告)日：2019-07-04
申请号：PCT/US2018/063512
申请日：2018-12-01
申请人： MICROSOFT TECHNOLOGY LICENSING, LLC
发明人： KEMPER, Jeremiah William , WALDBAUM, Brett Alan , KOON, Joshua Christopher
IPC分类号： G04G11/00 , G04G13/02
CPC分类号： G04G11/00 , A61M2021/0027 , A61M2021/0044 , A61M2021/0083 , F21V23/0485 , F21V33/0024 , G04G9/10 , G04G13/02
摘要： The disclosed technology is generally directed to mobile clock devices. In one example of the technology, a device includes a first screen, a second screen, and a controller. The second screen is physically coupled to the first screen, and is facing a different direction than the first screen. The controller is configured to cause the first screen to operate as a clock display. The controller is further configured to cause the second screen to provide indirect light such that the indirect light gradually increases beginning at a time proximate to a predetermined time until the predetermined time is reached.

2. 发明申请

WO2019115412A1 SYSTEM AND METHOD FOR DETERMINING SLEEP ONSET LATENCY 审中-公开
公开(公告)号：WO2019115412A1
公开(公告)日：2019-06-20
申请号：PCT/EP2018/084071
申请日：2018-12-10
申请人： KONINKLIJKE PHILIPS N.V.
发明人： TSONEVA, Tsvetomira Kirova , GARCIA MOLINA, Gary Nelson
IPC分类号： A61B5/048 , A61B5/11 , A61B5/00 , A61M21/02
CPC分类号： A61B5/4809 , A61B5/0476 , A61B5/048 , A61B5/1103 , A61B5/4812 , A61B5/4836 , A61B5/6804 , A61M21/00 , A61M21/02 , A61M2021/0016 , A61M2021/0022 , A61M2021/0027 , A61M2021/0044 , A61M2021/0055 , A61M2021/0072 , A61M2205/3313 , A61M2205/3375 , A61M2205/3553 , A61M2205/3561 , A61M2205/3569 , A61M2205/3584 , A61M2205/3592 , A61M2205/502 , A61M2209/088 , A61M2210/06 , A61M2230/04 , A61M2230/10 , A61M2230/14 , A61M2230/20 , A61M2230/40 , A61M2230/50 , A61M2230/63 , A61M2230/005
摘要： The present disclosure pertains to a system and method for determining sleep onset latency in a subject. The system is configured to generate output signals conveying information related to brain activity in the subject, determine sleep stages of the subject based on the output signals, determine a sleep onset moment in the subject based on the determined sleep stages, determine a sleep intention moment for the subject by: (i) detecting eye blinks in the subject based on the output signals, and determining the sleep intention moment responsive to the detected eye blinks ceasing for a predetermined period of time; and/or (ii) determining whether brain activity power in a target frequency band has breached a threshold power level based on the output signals, and determining the sleep intention moment responsive to a breach; and determine the sleep onset latency based on the sleep onset moment and the sleep intention moment.

3. 发明申请

WO2018094232A1 METHODS AND SYSTEMS FOR NEURAL STIMULATION VIA VISUAL, AUDITORY AND PERIPHERAL NERVE STIMULATIONS 审中-公开
公开(公告)号：WO2018094232A1
公开(公告)日：2018-05-24
申请号：PCT/US2017062335
申请日：2017-11-17
申请人： COGNITO THERAPEUTICS INC
发明人： MALCHANO ZACHARY JOHN HAMBRECHT , WILLIAMS MARTIN WARREN
IPC分类号： A61N1/36
CPC分类号： A61M21/00 , A61B3/113 , A61B5/024 , A61B5/0482 , A61B5/0484 , A61B5/0496 , A61B5/05 , A61B5/16 , A61B5/163 , A61B5/168 , A61B5/4836 , A61B5/4848 , A61B5/6803 , A61M2021/0027 , A61M2021/0044 , A61M2021/0072 , A61M2205/3375 , A61N1/0456 , A61N1/36025 , A61N1/36092 , A61N1/36132 , A61N5/0618 , A61N2005/0626 , A61N2005/0627 , A61N2005/0629 , A61N2005/0648 , A61N2005/0652 , A61N2005/0663 , A61N2005/0667 , G02C11/10 , G02C2200/10 , H05B37/0227
摘要： Systems and methods of the present disclosure are directed to systems and methods for treating cognitive dysfunction in a subject in need thereof. The system can include a light source and a speaker. A visual neural stimulation system provides, via the light source, visual stimulation having a first value of a first parameter. An auditory neural stimulation system provides, via the speaker, audio stimulation having a second value of the second parameter. A stimuli orchestration component selects, for a first time interval, one of the visual stimulation or the audio stimulation to vary based on a policy, selects, for the first time interval, the other of the visual stimulation or the audio stimulation to keep constant based on the policy, and provides causes the one of the visual neural stimulation system or the auditory neural stimulation system to vary the one of the visual stimulation or the audio stimulation.

4. 发明申请

WO2017099974A8 SYSTEMS FOR BRAIN STIMULATION DURING SLEEP AND METHODS OF USE THEREOF 审中-公开
标题翻译：用于睡眠期间脑刺激的系统及其使用方法
公开(公告)号：WO2017099974A8
公开(公告)日：2017-07-06
申请号：PCT/US2016062794
申请日：2016-11-18
申请人： XIA JUN
发明人： XIA JUN
IPC分类号： A61M21/00
CPC分类号： A61M21/00 , A61M21/02 , A61M35/00 , A61M2021/0016 , A61M2021/0022 , A61M2021/0027 , A61M2021/0044 , A61M2021/0066 , A61M2230/10 , A61M2230/18
摘要： The present invention relates to systems for brain stimulation during sleep and methods for increasing vividness of a subject's dreams or for directing the subject matter of a subject's dreams. The system comprises a brain stimulation module and at least one of a brain energy source, a hypnotic source, or both. The methods involve administering to a subject a brain energy molecule, a hypnotic, or both and providing to the subject during restorative sleep a sensory stimulation.
摘要翻译：本发明涉及用于睡眠期间脑刺激的系统和用于增加受试者梦想的生动性或用于指导受试者梦想的主题的方法。该系统包括脑刺激模块以及脑能量源，催眠源或两者中的至少一个。该方法涉及向受试者施用脑能量分子，催眠药或两者并在恢复性睡眠期间向受试者提供感官刺激。

5. 发明申请

WO2017101907A2 VORRICHTUNG ZUR NEURO-VASKULÄREN STIMULATION 审中-公开
标题翻译：神经血管刺激装置
公开(公告)号：WO2017101907A2
公开(公告)日：2017-06-22
申请号：PCT/DE2016/100580
申请日：2016-12-13
申请人： OTTO-VON-GUERICKE-UNIVERSITÄT MAGDEBURG, TTZ, PATENTWESEN
发明人： REHSE, Chris , DÜZEL, Emrah
IPC分类号： A61B5/0205 , A61B5/024 , A61B5/048 , A61B5/16 , A61B5/00 , A61M21/00 , A63B24/00 , A61B3/113 , A61B5/021 , A61B5/0482 , G09B7/02
CPC分类号： A61B5/0205 , A61B3/113 , A61B5/0022 , A61B5/021 , A61B5/02438 , A61B5/048 , A61B5/0482 , A61B5/16 , A61B5/4836 , A61B5/4839 , A61B5/6803 , A61B5/6817 , A61B5/6898 , A61B5/7405 , A61B5/7445 , A61B5/7455 , A61M21/00 , A61M2021/0016 , A61M2021/0022 , A61M2021/0027 , A61M2021/005 , A61M2021/0072 , A61M2205/3306 , A61M2205/3375 , A61M2205/3553 , A61M2205/3569 , A61M2205/3584 , A61M2205/3592 , A61M2205/505 , A61M2205/507 , A61M2209/088 , A61M2230/04 , A61M2230/06 , A61M2230/10 , A61M2230/18 , A61M2230/205 , A61M2230/30 , A61M2230/432 , A61M2230/65 , A61N1/0452 , A61N1/36 , A61N1/36003 , A63B22/0048 , A63B22/0076 , A63B22/02 , A63B22/0605 , A63B71/0619 , A63B2071/0625 , A63B2220/806 , A63B2220/807 , A63B2220/808 , A63B2220/836 , A63B2225/50 , A63B2230/06 , A63B2230/10 , A63B2230/30 , A63B2230/65 , G09B7/02 , G09B19/00 , G09B23/28 , A61M2230/005
摘要： Es wird eine Vorrichtung zur neuro-vaskulären Stimulation zumindest umfassend zumindest einen Gehirnaktivitätssensor, zumindest einen kardio-vaskulären Sensor, zumindest eine Recheneinheit und zumindest eine Ausgabeeinheit vorgeschlagen. Die Recheneinheit weist zumindest einen Aufgabenalgorithmus auf, wobei mittels der Recheneinheit Signale zumindest des Gehirnaktivitätssensors und des kardio-vaskulären Sensors empfangbar sind und eine Aufgabe, die in Korrelation mit zumindest den Signalen zumindest des Gehirnaktivitätssensors und den Signalen des kardio-vaskulären Sensors steht, mittels des Aufgabenalgorithmus' ermittelbar und mittels der Ausgabeeinheit ausgebbar ist.
摘要翻译：提出了一种用于神经血管刺激的装置，其至少包括至少一个脑活动传感器，至少一个心血管传感器，至少一个计算单元和至少一个输出单元。计算单元包括至少一个任务的算法，由运算单元的信号的装置中的至少所述Gehirnaktivit BEAR tssensors和心血管＆AUML;任传感器可以接收和任务，在与至少所述Gehirnaktivit BEAR tssensors的至少所述信号和治疗心的信号的相关 vaskular传感器，可以通过任务算法确定，并可以通过输出单元输出。

6. 发明申请

WO2017091758A1 METHODS AND SYSTEMS FOR PROVIDING STIMULI TO THE BRAIN 审中-公开
标题翻译：用于向大脑提供刺激的方法和系统
公开(公告)号：WO2017091758A1
公开(公告)日：2017-06-01
申请号：PCT/US2016/063651
申请日：2016-11-23
申请人： SANA HEALTH, INC.
发明人： HANBURY, Richand
IPC分类号： A61B5/00 , G02B27/01 , G02B27/02 , G06F3/01 , G08B6/00 , G09G5/00 , H04R1/00
CPC分类号： A61M21/02 , A61M2021/0022 , A61M2021/0027 , A61M2021/005 , A61M2205/3569 , A61M2205/3592 , A61M2205/505 , A61M2209/088
摘要： Visual and auditory stimuli are provided to a patient to treat various neurological disorders or conditions. The visual and auditory stimuli are provided by a wearable headset or sleep mask that may be comfortably worn by a user, such as in bed to induce sleep. The wearable headset or sleep mask is operated by a personal computing device of the user, such as smartphone, having downloaded and active thereon a control application or app for the therapy. The wearable headset or sleep mask also concurrently provides tactile stimuli, and the tactile stimulus is provided from bone conduction transducers that concurrently provides the auditory stimuli.
摘要翻译：向患者提供视觉和听觉刺激以治疗各种神经疾病或病症。视觉和听觉刺激由佩戴式耳机或睡眠面罩提供，佩戴式耳机或睡眠面罩可以由使用者舒适地佩戴，例如在床上诱导睡眠。可穿戴耳机或睡眠面罩由用户的个人计算设备（例如智能手机）操作，该用户的个人计算设备已经下载并在其上激活用于治疗的控制应用或应用。可穿戴耳机或睡眠面罩也同时提供触觉刺激，并且从骨传导传感器提供触觉刺激，其同时提供听觉刺激。

7. 发明申请

WO2017085083A1 AN APPARATUS AND METHOD FOR TREATING A NEUROLOGICAL DISORDER OF THE AUDITORY SYSTEM 审中-公开
标题翻译：一种治疗听力系统神经系统疾病的装置和方法
公开(公告)号：WO2017085083A1
公开(公告)日：2017-05-26
申请号：PCT/EP2016/077781
申请日：2016-11-15
申请人： NEUROMOD DEVICES LIMITED
发明人： HUGHES, Stephen , O'NEILL, Ross , CONLON, Brendan , HAMILTON, Caroline , D'ARCY, Shona
IPC分类号： A61F11/04 , A61B5/00 , A61M21/00 , H04R25/00
CPC分类号： A61B5/128 , A61B5/4833 , A61B5/4848 , A61B5/7455 , A61F11/04 , A61M21/02 , A61M2021/0027 , A61M2021/0072 , A61N1/0456 , A61N1/0548 , A61N1/36014 , A61N1/36034 , A61N1/36036 , A61N1/361 , H04R25/75 , H04R2460/13
摘要： An apparatus for use in treating a neurological disorder of the auditory system, comprising a stimulus generation unit (101) and a somatosensory stimulation unit (102); the stimulus generation unit operable to analyse an audio signal, said audio signal comprising a first component comprising a broadband or white noise component and a second component comprising a plurality of complex tone bursts, and generate a plurality of actuation signals representative of at least one of the first or second component of said audio signal and further to spectrally modify said audio signal to generate a binaural modified audio signal for delivery to a subject; and wherein said somatosensory stimulation unit comprises: an array of stimulators each of which can be independently actuated to apply a somatosensory stimulation to the subject with the modified audio signal, and an input for receiving the plurality of actuation signals from said stimulus generation unit and directing individual actuation signals in a predetermined pattern to individual stimulators in the array, the stimulus generation unit being further configured to introduce a delay between the plurality of actuation signals representative of said audio signal and the binaural modified audio signal.
摘要翻译：一种用于治疗听觉系统神经紊乱的设备，包括刺激产生单元（101）和体感刺激单元（102）所述刺激生成单元可操作以分析音频信号，所述音频信号包括包含宽带或白噪声分量的第一分量和包含多个复调音丛集的第二分量，并且生成表示以下中的至少一个的多个致动信号：所述音频信号的第一或第二分量，并且还用于对所述音频信号进行频谱修改以生成双耳修改的音频信号以传送至对象; 并且其中所述体感刺激单元包括：刺激器阵列，其中的每一个可以被独立地致动以将体感刺激应用于具有修改的音频信号的对象;以及输入，用于从所述刺激生成单元接收多个致动信号并且引导以预定模式将单独致动信号提供给阵列中的各个刺激器，所述刺激生成单元进一步被配置为在表示所述音频信号的所述多个致动信号和所述双耳修改的音频信号之间引入延迟。

8. 发明申请

WO2016149416A1 METHODS AND SYSTEMS FOR DIAGNOSING AND TREATING HEALTH AILMENTS 审中-公开
标题翻译：用于诊断和治疗健康用品的方法和系统
公开(公告)号：WO2016149416A1
公开(公告)日：2016-09-22
申请号：PCT/US2016/022710
申请日：2016-03-16
申请人： MAGIC LEAP, INC.
发明人： SAMEC, Nicole, Elizabeth , MACNAMARA, John, Graham , HARRISES, Christopher, M. , SCHOWENGERDT, Brian, T. , ABOVITZ, Rony , BAERENRODT, Mark
IPC分类号： G02B27/22 , G02B6/26
CPC分类号： G02B27/0172 , A61B3/0008 , A61B3/0025 , A61B3/0033 , A61B3/005 , A61B3/0058 , A61B3/0091 , A61B3/022 , A61B3/024 , A61B3/028 , A61B3/032 , A61B3/063 , A61B3/066 , A61B3/08 , A61B3/085 , A61B3/09 , A61B3/10 , A61B3/1005 , A61B3/1015 , A61B3/102 , A61B3/103 , A61B3/1035 , A61B3/112 , A61B3/113 , A61B3/12 , A61B3/1216 , A61B3/1241 , A61B3/13 , A61B3/135 , A61B3/14 , A61B3/16 , A61B3/165 , A61B5/0059 , A61B5/0066 , A61B5/0077 , A61B5/01 , A61B5/0476 , A61B5/0496 , A61B5/14532 , A61B5/1455 , A61B5/14552 , A61B5/14555 , A61B5/4064 , A61B5/6803 , A61B8/10 , A61B8/4483 , A61B8/461 , A61B8/5207 , A61B2562/0204 , A61B2562/0219 , A61B2562/0238 , A61B2562/0247 , A61B2562/04 , A61F7/007 , A61F7/0085 , A61F9/0026 , A61F9/00823 , A61F2007/0004 , A61F2007/006 , A61F2007/0064 , A61F2007/0086 , A61F2009/00863 , A61H1/00 , A61H5/00 , A61H2201/165 , A61M11/02 , A61M21/02 , A61M2021/0022 , A61M2021/0027 , A61M2021/0066 , A61M2205/3375 , A61M2205/507 , A61N5/0618 , A61N5/062 , A61N2005/0626 , A61N2005/0648 , A61N2005/0663 , A61N2005/067 , G02B21/0028 , G02B21/0032 , G02B21/0076 , G02B27/0093 , G02B27/0176 , G02B27/0179 , G02B2027/0138 , G02B2027/014 , G02B2027/0185 , G02C7/027 , G06K9/00671 , G06T3/40 , G06T5/008 , G06T5/009 , G06T7/0014 , G06T11/001 , G06T19/006 , G06T2207/10024 , G06T2207/10048 , G06T2207/10148 , G06T2207/10152 , G06T2207/20024 , G06T2207/20208 , G06T2207/30041
摘要： Configurations are disclosed for a health system to be used in various healthcare applications, e.g., for patient diagnostics, monitoring, and/or therapy. The health system may comprise a light generation module to transmit light or an image to a user, one or more sensors to detect a physiological parameter of the user's body, including their eyes, and processing circuitry to analyze an input received in response to the presented images to determine one or more health conditions or defects.
摘要翻译：公开了用于健康系统的配置，以用于各种保健应用，例如用于患者诊断，监测和/或治疗。卫生系统可以包括用于向用户传输光或图像的光生成模块，用于检测包括他们的眼睛的用户身体的生理参数的一个或多个传感器，以及响应于所呈现的接收到的输入来分析输入的处理电路图像确定一个或多个健康状况或缺陷。

9. 发明申请

WO2016121755A1 睡眠誘導装置、制御方法、およびコンピュータ読み取り可能な記録媒体审中-公开
标题翻译：休眠诱导装置，控制方法和计算机可读记录介质
公开(公告)号：WO2016121755A1
公开(公告)日：2016-08-04
申请号：PCT/JP2016/052177
申请日：2016-01-26
申请人：ヤマハ株式会社
发明人：森島　守人 , 山木　清志 , 川▲原▼　毅彦 , 石原　淳
IPC分类号： A61M21/02
CPC分类号： A61M21/02 , A61B5/0022 , A61B5/0205 , A61B5/02108 , A61B5/0476 , A61B5/1116 , A61B5/113 , A61B5/4812 , A61B5/486 , A61B5/6814 , A61B5/6824 , A61B5/6887 , A61B5/6891 , A61B5/7278 , A61B5/7405 , A61M2021/0027 , A61M2205/3303 , A61M2230/04 , A61M2230/10 , A61M2230/63
摘要：　睡眠誘導装置は、被験者に刺激を付与する刺激付与部を制御するものであり、被験者の生体リズムを取得し、取得した被験者の生体リズムから当該被験者の睡眠深度を推定し、取得した被験者の生体リズムと被験者について推定される現在の睡眠深度とに応じて当該被験者に刺激を付与するよう、刺激付与部を制御する。
摘要翻译：该睡眠诱导装置被配置为控制用于向对象施加刺激的刺激应用单元。睡眠诱导装置获取受试者的生殖节律，从所获取的受试者的生殖节律估计受试者的睡眠阶段，并且控制刺激应用单元，使得根据所获取的生殖节律和估计的电流对受试者施加刺激受试者的睡眠阶段。

10. 发明申请

WO2016087983A1 SYSTEM AND METHOD FOR INCREASING THE RESTORATIVE VALUE OF A NAP 审中-公开
标题翻译：增加NAP恢复价值的系统和方法
公开(公告)号：WO2016087983A1
公开(公告)日：2016-06-09
申请号：PCT/IB2015/059057
申请日：2015-11-24
申请人： KONINKLIJKE PHILIPS N.V.
发明人： GARCIA MOLINA, Gary Nelson
IPC分类号： A61N1/36 , A61B5/048 , A61M21/02
CPC分类号： A61N1/36078 , A61B5/04845 , A61B5/4812 , A61B5/4836 , A61M21/02 , A61M2021/0016 , A61M2021/0027 , A61M2021/0044 , A61M2205/52 , A61M2230/10 , A61M2230/005
摘要： The present disclosure pertains to a system configured to manage a sleep session of a subject. In some embodiments, the sleep session is a nap and the system is configured to increase the restorative value of the nap by enhancing and/or maintaining sleep slow waves (and/or slow wave activity estimated using an EEG) in the subject during the nap with sensory stimuli. The present system is configured to enhance restorative sleep during a nap by delivering sensory stimulation to the subject during lighter NREM sleep stages (e.g., during a portion of stage N2 sleep) while still avoiding arousals. In some embodiments, the system is configured to facilitate a "powernap" by delivering the sensory stimulation to the subject in such a way so as to prevent transition into deep sleep(e.g., stage N3 sleep).
摘要翻译：本公开涉及被配置为管理对象的睡眠会话的系统。在一些实施例中，睡眠会话是小睡，并且系统被配置为通过在睡眠期间增强和/或维持受试者睡眠慢波（和/或使用EEG估计的慢波活动）来增加睡眠的恢复值与感官刺激。本系统被配置为通过在较轻的NREM睡眠阶段（例如，在N2阶段的睡眠期间的一部分期间）向对象施加感觉刺激，同时仍然避免觉醒，来增强睡眠期间的恢复性睡眠。在一些实施例中，该系统被配置为通过以这样的方式将感觉刺激递送给受试者来促进“功率抽吸”，以便防止过渡到深度睡眠（例如，阶段N3睡眠）。

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