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1. 发明申请

WO2017205809A1 NON-CONTACT ACOUSTIC RADIATION FORCE BASED (ARF-BASED) GENERATION OF BROAD BANDWIDTH MECHANICAL WAVES USING AIR-COUPLED ULTRASOUND 审中-公开
标题翻译：基于非接触声辐射力（基于ARF）使用空气耦合超声波产生宽带机械波
公开(公告)号：WO2017205809A1
公开(公告)日：2017-11-30
申请号：PCT/US2017/034801
申请日：2017-05-26
申请人： UNIVERSITY OF WASHINGTON
发明人： AMBROZINSKI, Lukasz , O'DONNELL, Matthew , PELIVANOV, Ivan , YOON, Soon Joon , LI, David , SONG, Shaozhen , WANG, Ruikang K. , SHEN, Tueng T. , GAO, Liang
IPC分类号： A61B5/00 , A61B8/08 , A61B8/10 , G01N29/00 , G01N29/26 , G01N29/06
CPC分类号： A61B5/442 , A61B5/0051 , A61B5/0066 , A61B8/10 , A61B8/485 , G01N29/0654 , G01N29/221 , G01N29/2456 , G01N29/26 , G01N2291/02475 , G10K11/26
摘要： Methods and systems for measuring one or more properties of a soft material employ air transmitted ultrasound that is reflected from the soft material to generate a mechanical wave in the soft material. A method of measuring one or more properties of a soft material includes transmitting ultrasound through air to an interface boundary between the soft material and air. Force is applied to the soft material by reflecting the ultrasound from the soft material. A mechanical wave is generated in the soft material as a result of the force applied to the soft material. Propagation of the mechanical wave in the soft material is measured with an imaging system. One or more properties of the soft material is determined based on the measured propagation of the mechanical wave in the soft material.
摘要翻译：用于测量软材料的一个或多个性质的方法和系统采用由软材料反射的空气传播超声波以在软材料中产生机械波。测量软材料的一种或多种性质的方法包括将超声波通过空气传输到软材料和空气之间的界面边界。通过反射来自软材料的超声波，将力施加到软材料上。由于施加到软材料上的力，在软材料中产生机械波。用成像系统测量软质材料中机械波的传播。软材料的一种或多种性质是根据测量的软材料中机械波的传播来确定的。

2. 发明申请

WO2015142331A8 EYE IMAGING APPARATUS AND SYSTEMS 审中-公开
标题翻译：眼睛成像装置和系统
公开(公告)号：WO2015142331A8
公开(公告)日：2016-10-20
申请号：PCT/US2014031263
申请日：2014-03-19
申请人： VISUNEX MEDICAL SYSTEMS CO LTD , SU WEI
发明人： SU WEI , XU LI
IPC分类号： A61B3/10 , A61B3/14
CPC分类号： A61B3/14 , A61B3/1208 , A61B3/132 , A61B8/10
摘要： Various embodiments of an eye imaging apparatus are disclosed. In some embodiments, the eye imaging apparatus may comprise a light source, an image sensor, a hand-held computing device, and an adaptation module. The adaptation module comprises a microcontroller and a signal processing unit configured to adapt the hand¬ held computing device to control the light source and the image sensor. In some embodiments, the imaging apparatus may comprise an exterior imaging module to image an anterior segment of the eye and/or a front imaging module to image a posterior segment of the eye. The eye imaging apparatus may be used in an eye imaging medical system. The images of the eye may be captured by the eye imaging apparatus, transferred to an image computing module, stored in an image storage module, and displayed in an image review module.
摘要翻译：公开了一种眼睛成像设备的各种实施例。在一些实施例中，眼睛成像设备可以包括光源，图像传感器，手持计算设备和适配模块。适配模块包括微控制器和信号处理单元，其被配置为使手持计算设备适配以控制光源和图像传感器。在一些实施例中，成像设备可以包括外部成像模块以对眼睛的前部和/或前部成像模块进行成像以对眼睛的后部成像。眼睛成像装置可以用于眼睛成像医疗系统。眼睛的图像可以由眼睛成像装置捕获，转移到存储在图像存储模块中的图像计算模块，并且被显示在图像审查模块中。

3. 发明申请

WO2016149428A1 AUGMENTED REALITY PULSE OXIMETRY 审中-公开
标题翻译：增强现实脉冲氧化
公开(公告)号：WO2016149428A1
公开(公告)日：2016-09-22
申请号：PCT/US2016/022724
申请日：2016-03-16
申请人： MAGIC LEAP, INC.
发明人： SAMEC, Nicole Elizabeth , KAEHLER, Adrian
IPC分类号： A61B5/1455 , A61B3/12
CPC分类号： G02B27/0172 , A61B3/0008 , A61B3/0025 , A61B3/0033 , A61B3/005 , A61B3/0058 , A61B3/0091 , A61B3/022 , A61B3/024 , A61B3/028 , A61B3/032 , A61B3/063 , A61B3/066 , A61B3/08 , A61B3/085 , A61B3/09 , A61B3/10 , A61B3/1005 , A61B3/1015 , A61B3/102 , A61B3/103 , A61B3/1035 , A61B3/112 , A61B3/113 , A61B3/12 , A61B3/1216 , A61B3/1241 , A61B3/13 , A61B3/135 , A61B3/14 , A61B3/16 , A61B3/165 , A61B5/0059 , A61B5/0066 , A61B5/0077 , A61B5/01 , A61B5/0476 , A61B5/0496 , A61B5/14532 , A61B5/1455 , A61B5/14552 , A61B5/14555 , A61B5/4064 , A61B5/6803 , A61B8/10 , A61B8/4483 , A61B8/461 , A61B8/5207 , A61B2562/0204 , A61B2562/0219 , A61B2562/0238 , A61B2562/0247 , A61B2562/04 , A61F7/007 , A61F7/0085 , A61F9/0026 , A61F9/00823 , A61F2007/0004 , A61F2007/006 , A61F2007/0064 , A61F2007/0086 , A61F2009/00863 , A61H1/00 , A61H5/00 , A61H2201/165 , A61M11/02 , A61M21/02 , A61M2021/0022 , A61M2021/0027 , A61M2021/0066 , A61M2205/3375 , A61M2205/507 , A61N5/0618 , A61N5/062 , A61N2005/0626 , A61N2005/0648 , A61N2005/0663 , A61N2005/067 , G02B21/0028 , G02B21/0032 , G02B21/0076 , G02B27/0093 , G02B27/0176 , G02B27/0179 , G02B2027/0138 , G02B2027/014 , G02B2027/0185 , G02C7/027 , G06K9/00671 , G06T3/40 , G06T5/008 , G06T5/009 , G06T7/0014 , G06T11/001 , G06T19/006 , G06T2207/10024 , G06T2207/10048 , G06T2207/10148 , G06T2207/10152 , G06T2207/20024 , G06T2207/20208 , G06T2207/30041
摘要： One embodiment is directed to a system comprising a head-mounted member removably coupleable to the user's head; one or more electromagnetic radiation emitters coupled to the head-mounted member and configured to emit light with at least two different wavelengths toward at least one of the eyes of the user; one or more electromagnetic radiation detectors coupled to the head-mounted member and configured to receive light reflected after encountering at least one blood vessel of the eye; and a controller operatively coupled to the one or more electromagnetic radiation emitters and detectors and configured to cause the one or more electromagnetic radiation emitters to emit pulses of light while also causing the one or more electromagnetic radiation detectors to detect levels of light absorption related to the emitted pulses of light, and to produce an output that is proportional to an oxygen saturation level in the blood vessel.
摘要翻译：一个实施例涉及一种系统，包括可拆卸地与使用者头部连接的头戴式部件; 一个或多个电磁辐射发射器，其耦合到所述头部安装构件并且被配置为朝向所述用户的眼睛中的至少一个发射具有至少两个不同波长的光; 一个或多个电磁辐射探测器，其耦合到所述头部安装构件并且被配置为接收在遇到所述眼睛的至少一个血管之后反射的光; 以及控制器，其可操作地耦合到所述一个或多个电磁辐射发射器和检测器，并且被配置为使所述一个或多个电磁辐射发射器发出光脉冲，同时还使所述一个或多个电磁辐射检测器检测与发出的光脉冲，并且产生与血管中的氧饱和度水平成比例的输出。

4. 发明申请

WO2016092563A2 SMART EYE SYSTEM FOR VISUOMOTOR DYSFUNTION DIAGNOSIS AND ITS OPERANT CONDITIONING 审中-公开
标题翻译：智能眼睛系统用于视力机能障碍诊断及其操作条件
公开(公告)号：WO2016092563A2
公开(公告)日：2016-06-16
申请号：PCT/IN2015000448
申请日：2015-12-11
申请人： INDIAN INST OF TECHNOLOGY GANDHINAGAR
发明人： UTTAMA LAHIRI , ANIRBAN DUTTA , ABHIJIT DAS
IPC分类号： A61B5/00
CPC分类号： A61B3/113 , A61B3/14 , A61B5/0075 , A61B5/0205 , A61B5/04012 , A61B5/0402 , A61B5/0476 , A61B5/04842 , A61B5/04845 , A61B5/0488 , A61B5/0507 , A61B5/055 , A61B5/1103 , A61B5/4023 , A61B5/4064 , A61B5/7278 , A61B8/10
摘要： Disclosed herein is a system that uses an eye tracker for diagnosing and facilitating rehabilitation therapy of a patient suffering from disability. The system creates a human machine interface (HMI) that integrates various low cost biosensors and artificial sensors for conducting rehabilitation therapy. The system combines spinal and supra-spinal feedback of the patient with the operant conditioning to facilitate visuomotor balance therapy (VBT), thereby reducing fall risk in disability survivors. The operant conditioning setup for shaping of visuomotor learning to bring about new behavior or to modify a certain aspect of an existing behavior is used for rehabilitation therapy that includes a behaviour response apparatus, a reward delivery system, a stimulus delivery system, and a behaviour control system. The system can also be extended to the patient's home for providing telerehabilitation therapy.
摘要翻译：本文公开了一种使用眼动仪用于诊断和促进患有残疾的患者的康复治疗的系统。该系统创建了一个人机界面（HMI），集成了各种低成本生物传感器和人造传感器，用于进行康复治疗。该系统将患者的脊柱和超脊柱反馈与手术调理相结合，以促进视觉运动平衡疗法（VBT），从而减少残疾幸存者的跌倒风险。用于矫正视觉运动学习以产生新行为或修改现有行为的某一方面的操作性调节设置用于包括行为反应设备，奖励传递系统，刺激传递系统和行为控制的康复治疗系统。该系统还可以扩展到病人的家中，提供远程康复治疗。

5. 发明申请

WO2016077173A1 OPTICAL COHERENCE ELASTOGRAPHY TO ASSESS BIOMECHANICS AND DETECT PROGRESSION OF OCULAR AND OTHER TISSUES DEGENERATIVE DISEASES 审中-公开
标题翻译：评估生物力学的光学相干弹性学和检测其他组织变性疾病的进展
公开(公告)号：WO2016077173A1
公开(公告)日：2016-05-19
申请号：PCT/US2015/059472
申请日：2015-11-06
申请人： UNIVERSITY OF HOUSTON SYSTEM
发明人： LARIN, Kirill V. , LI, Jiasong , SINGH, Manmohan , WU, Chen , AGLYAMOV, Salavat
IPC分类号： A61B3/10 , A61B5/00
CPC分类号： A61B3/0025 , A61B3/102 , A61B3/16 , A61B3/165 , A61B5/0051 , A61B5/0053 , A61B5/0066 , A61B5/0093 , A61B5/0097 , A61B8/10 , A61B8/485 , A61B2576/00
摘要： An excitation force (internal or external) and phase-sensitive optical coherence elastography (OCE) system, used in conjunction with a data analyzing algorithm, is capable of measuring and quantifying biomechanical parameters of tissues in situ and in vivo . The method was approbated and demonstrated on an example of the system that combines a pulsed ultrasound system capable of producing an acoustic radiation force on the crystalline lens surface and a phase-sensitive optical coherence tomography (OCT) system for measuring the lens displacement caused by the acoustic radiation force. The method allows noninvasive and nondestructive quantification of tissue mechanical properties. The noninvasive measurement method also utilizes phase-stabilized swept source optical coherence elastography (PhS-SSOCE) to distinguish between tissue stiffness, such as that attributable to disease, and effects on measured stiffness that result from external factors, such as pressure applied to the tissue. Preferably, the method is used to detect tissue stiffness and to evaluate the presence of its stiffness even if it is affected by other factors such as intraocular pressure (IOP) in the case of cornea, sclera, or the lens. This noninvasive method can evaluate the biomechanical properties of the tissues in vivo for detecting the onset and progression of degenerative or other diseases (such as keratoconus).
摘要翻译：与数据分析算法结合使用的激发力（内部或外部）和相敏光学相干弹性成像（OCE）系统能够测量和定量原位和体内组织的生物力学参数。该方法被认为并证明了该系统的一个实例，其结合了能够在晶状体表面上产生声辐射力的脉冲超声系统和相敏光学相干断层扫描（OCT）系统，用于测量由声辐射力。该方法允许组织机械性质的无创和非破坏性定量。非侵入性测量方法还利用相位稳定扫描光学相干弹性成像（PhS-SSOCE）来区分组织刚度，例如可归因于疾病的组织刚度，以及由外部因素（例如施加到组织上的压力）引起的测量刚度的影响。优选地，该方法用于检测组织刚度并评估其刚度的存在，即使其受角膜，巩膜或透镜的情况下的其他因素如眼内压（IOP）的影响。这种非侵入性方法可以评估体内组织的生物力学性质，以检测退行性或其他疾病（如圆锥角膜）的发生和发展。

6. 发明申请

WO2016033590A1 SYSTEMS AND METHODS FOR ANALYZING THE EYE 审中-公开
标题翻译：用于分析眼睛的系统和方法
公开(公告)号：WO2016033590A1
公开(公告)日：2016-03-03
申请号：PCT/US2015/047747
申请日：2015-08-31
申请人： BERESTKA, John
发明人： BERESTKA, John , BERESTKA, Noah John
IPC分类号： A61B3/14
CPC分类号： A61B3/135 , A61B3/0025 , A61B3/0041 , A61B3/0083 , A61B3/14 , A61B8/10
摘要： Systems and methods for imaging an eye are disclosed. The systems and methods may include at least one plenoptic camera. The systems and methods may include an illumination source with a plurality of lights.
摘要翻译：公开了用于成像眼睛的系统和方法。系统和方法可以包括至少一个全光照相机。系统和方法可以包括具有多个灯的照明源。

7. 发明申请

WO2015185682A3 TOPOGRAPHY MODULE FOR OPTHALMOLOGICAL DEVICES WITH A DISTANCE-INDEPENDENT KERATOMETER AND METHOD FOR THE USE THEREOF 审中-公开
标题翻译： TOPOGRAPHIE模块与距离无关角膜曲率测量装置及其使用方法的眼科器件
公开(公告)号：WO2015185682A3
公开(公告)日：2016-01-21
申请号：PCT/EP2015062494
申请日：2015-06-04
申请人： ZEISS CARL MEDITEC AG
发明人： REICH MATTHIAS , FUCHS RICO
IPC分类号： A61B3/107
CPC分类号： A61B3/107 , A61B3/10 , A61B3/1005 , A61B3/1035 , A61B8/10 , A61F2009/00882 , G01B11/2513
摘要： The invention relates to a module for ophthalmological devices which enable said ophthalmological devices to carry out keratometry and topography measurements of the eye. The proposed topography module is provided for ophthalmological devices with a distance-in dependent keratometer. According to the invention, the topography module, which is used to generate the luminous pattern, is arranged in a fixed or moveable manner in the beam path between the ophthalmological device and the eye. The provided control unit is provided to control the topography module for generating luminous patterns. The provided evaluation unit is also suitable to carry out keratometric as well as topographic evaluations of the reflection images of an eye, captured and transmitted by the detection unit. The solution of said invention enables ophthalmological devices, which are equipped with a distance-independent keratometer, to carry out additional topographical measurements on the eye.
摘要翻译：本发明涉及一种用于通过该眼用装置然后能够实现下一个角膜曲率也地形测量在眼睛上的眼科装置的模块。所提出的地形模块提供了眼用装置与一个独立的距离角膜曲率测量装置。根据本发明，是服务地形模块固定或可移动地布置在所述眼科装置和眼睛之间的光路发光图案的产生。现有的控制单元是根据所述位置，用于产生光图案的形貌模块来控制。此外，本评估单元适于分析由所述检测单元拍摄的图像和眼睛角膜两者的发送反射图像和地形。与本解决方案是可能的具有一距离有关的角膜曲率计测定装置眼科装置附加地实现在眼睛地形测量。

8. 发明申请

WO2015127417A1 DISPOSABLE EYEPIECE SYSTEM FOR AN ULTRASONIC EYE SCANNING APPARATUS 审中-公开
标题翻译：用于超声波眼睛扫描仪的可替代眼镜系统
公开(公告)号：WO2015127417A1
公开(公告)日：2015-08-27
申请号：PCT/US2015/017213
申请日：2015-02-24
申请人： ARCSCAN, INC.
发明人： HEATH, Gary , LEVIEN, Andrew, K. , WATSON, John, D.
IPC分类号： A61B8/10
CPC分类号： A61B8/10 , A61B8/4209 , A61B8/4422
摘要： A disposable eye piece system, including the eye piece and other disposable components, for a precision ultrasonic scanning apparatus is disclosed. The eye piece includes a fill port, a vent port and a drain port molded into the base of the eye piece. An RF Identification chip may be molded into the plastic base of the eye piece or, alternately into the conformable face seal of the eye piece. The components of a disposable eye piece system form an integrated disposable package that can be assembled, packaged, transported and used while maintaining the eye piece and saline solution in a sterile condition. The protective shipping container 1) protects the eye piece from damage, human contact and exposure to ambient air during shipping and storage and 2) allows the scanning physician or technician to attach the eye piece to the scanning machine without compromising the sterile condition of the eye piece.
摘要翻译：公开了一种用于精密超声波扫描装置的包括眼部件和其它一次性部件的一次性眼罩系统。眼部件包括模制到眼部底部的填充口，排气口和排出口。 RF识别芯片可以模制到眼部件的塑料底座中，或者可以模制成眼部件的适形表面密封件。一次性眼睛片系统的组件形成一体化的一次性包装，其可以组装，包装，运输和使用，同时将眼膜和盐溶液保持在无菌状态。保护性运输容器1）保护眼部件在运输和储存过程中免受损坏，人体接触和暴露于环境空气中; 2）允许扫描医师或技术人员将眼睛部件附着在扫描机上，而不会影响眼睛的无菌状况片。

9. 发明申请

WO2014145007A1 ULTRASOUND PROBE 审中-公开
标题翻译：超声探头
公开(公告)号：WO2014145007A1
公开(公告)日：2014-09-18
申请号：PCT/US2014/029641
申请日：2014-03-14
申请人： EAGLEYEMED
发明人： AMBLE, Ravi , RAZA, Farooq
IPC分类号： A61B8/00
CPC分类号： A61B8/5207 , A61B8/0866 , A61B8/0883 , A61B8/0891 , A61B8/10 , A61B8/145 , A61B8/4411 , A61B8/4455 , A61B8/4472 , A61B8/4488 , A61B8/4494 , A61B8/486 , A61B8/488 , A61B8/54 , A61B8/546 , A61B8/56 , G01S7/003 , G01S7/52079 , G01S7/5208 , G01S7/52082
摘要： In one general embodiment, an ultrasound probe includes a housing configured for grasping by a human hand; an array of transducers for transducing sound waves into electrical signals; a circuit board in the housing, the circuit board having a plurality of leads, each of the transducers being coupled to at least an associated one of the leads; processing circuitry in the housing and coupled to the circuit board for processing the electrical signals, or derivatives of the electrical signals, into sonogram data; and an output device for outputting the sonogram data.
摘要翻译：在一个一般实施例中，超声波探头包括构造成用于由人手抓握的壳体; 用于将声波转换成电信号的换能器阵列; 所述电路板在所述壳体中，所述电路板具有多个引线，每个所述换能器耦合到至少相关联的引线之一; 壳体中的处理电路并耦合到电路板，用于将电信号或电信号的导数处理成超声图数据; 以及用于输出声波图数据的输出装置。

10. 发明申请

WO2014127242A2 AQUABLATION AQUABEAM EYE SURGERY METHODS AND APPARATUS 审中-公开
公开(公告)号：WO2014127242A2
公开(公告)日：2014-08-21
申请号：PCT/US2014/016491
申请日：2014-02-14
申请人： PROCEPT BIOROBOTICS CORPORATION
发明人： ALJURI, Nikolai , MANTRI, Surag
IPC分类号： A61B17/3203
CPC分类号： A61B17/3203 , A61B5/0059 , A61B5/055 , A61B8/0841 , A61B8/10 , A61B8/12 , A61B8/14 , A61B8/4254 , A61B8/445 , A61B8/463 , A61B8/466 , A61B8/483 , A61B34/25 , A61B2017/32032 , A61B2034/2048 , A61B2090/3784 , A61F9/00736 , A61F2009/00844 , A61F2009/00868 , A61F2009/0087 , A61F2009/00878 , A61F2009/00887 , A61F2009/00891
摘要： A fluid jet is directed at tissue to erode tissue with a controlled amount of ablative energy of a jet. Embodiments as described herein can provide controlled removal of ocular tissue, and can remove a pre-defined volume having a pre-determined shape, for example. The accurate tissue removal as described herein can have many applications, such as removal of the lens for cataract surgery to more completely remove the cortex and nucleus of the lens and to separate layers of the lens. The length of an ablation depth extending from an opening that releases the jet can be controlled, and the angle and longitudinal position of the opening can be controlled together, in order to ablate a pre-determined volume of tissue having the surface profile.
摘要翻译：流体射流被引导到组织以用受控量的射流的烧蚀能量侵蚀组织。例如，本文所述的实施例可以提供对眼组织的受控去除，并且可以移除具有预定形状的预定体积。如本文所述的精确的组织去除可以具有许多应用，例如去除用于白内障手术的晶状体以更完全地去除晶状体的皮层和细胞核并分离晶状体层。可以控制从释放射流的开口延伸的消融深度的长度，并且可以一起控制开口的角度和纵向位置，以便消融具有表面轮廓的预定体积的组织。

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