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1. 发明申请

WO1997027897A1 A DEVICE, SYSTEM AND METHOD FOR INTERSTITIAL TRANSVASCULAR INTERVENTION 审中-公开
标题翻译：一种用于间质性转移性干预的装置，系统和方法
公开(公告)号：WO1997027897A1
公开(公告)日：1997-08-07
申请号：PCT/US1997001459
申请日：1997-01-31
申请人： TRANSVASCULAR, INC. , MAKOWER, Joshua
发明人： TRANSVASCULAR, INC.
IPC分类号： A61M29/00
CPC分类号： A61B17/12022 , A61B1/3137 , A61B17/00234 , A61B17/00491 , A61B17/0057 , A61B17/0643 , A61B17/11 , A61B17/12045 , A61B17/12109 , A61B17/12136 , A61B17/12181 , A61B17/1219 , A61B17/3417 , A61B17/3496 , A61B18/00 , A61B18/1445 , A61B18/1477 , A61B18/1492 , A61B18/24 , A61B90/361 , A61B90/40 , A61B2017/00243 , A61B2017/00247 , A61B2017/00252 , A61B2017/00504 , A61B2017/0641 , A61B2017/1107 , A61B2017/1139 , A61B2017/12127 , A61B2017/22038 , A61B2017/22077 , A61B2017/306 , A61B2017/347 , A61B2017/3488 , A61B2018/00392 , A61B2018/00404 , A61B2018/00869 , A61B2018/1425 , A61B2018/1475 , A61B2090/378 , A61B2090/3925 , A61B2090/3929 , A61B2090/3958 , A61F2/07 , A61F2/2493 , A61F2/90 , A61F2/95 , A61F2002/30079 , A61F2002/8486 , A61F2210/009 , A61M2025/0076 , A61M2025/0096 , A61M2025/1052
摘要： This invention is devices, systems and methods for trans-vascular interstitial interventions, including trans-vascular, catheter based vascular bypass, transmyocardial re-vascularization, bypass grafting of blood vessels, and interstitial surgical/interventional procedures wherein a catheter is advanced trans-lumenal through the vasculature (2) to a desired location (OB) and an operative instrument (5) is passed through the wall (2) of a blood vessel (2) and to a target location (3) (e.g., another blood vessel, an organ, a tumor, another anatomical structure) such that one or more operative devices may be advanced to the target location to perform the desired operative or interventional procedure.
摘要翻译：本发明是用于跨血管间质干预的装置，系统和方法，包括跨血管，基于导管的血管旁路，经心肌再血管化，血管旁路移植和间质性外科/介入手术，其中导管是跨腔内通过脉管系统（2）到达期望的位置（OB），并且手术器械（5）穿过血管（2）的壁（2）和目标位置（3）（例如，另一个血管，器官，肿瘤，另一解剖结构），使得一个或多个手术装置可以前进到目标位置以执行期望的手术或介入手术。

2. 发明申请

WO1997027898A1 METHODS AND APPARATUS FOR CONNECTING OPENINGS FORMED IN ADJACENT BLOOD VESSELS OR OTHER ANATOMICAL STRUCTURES 审中-公开
标题翻译：用于连接相邻血管或其他解剖结构中形成的开口的方法和装置
公开(公告)号：WO1997027898A1
公开(公告)日：1997-08-07
申请号：PCT/US1997001468
申请日：1997-01-31
申请人： TRANSVASCULAR, INC. , EVARD, Philip, C. , FLAHERTY, J., C. , GARIBOTTO, John, T. , MACAULAY, Patrick, E. , MACHOLD, Timothy, R. , MAKOWER, Joshua , WHITT, Jason, B. , ROTH, Alex, T.
发明人： TRANSVASCULAR, INC.
IPC分类号： A61M29/00
CPC分类号： A61B1/3137 , A61B17/00234 , A61B17/00491 , A61B17/0643 , A61B17/11 , A61B18/00 , A61B18/1445 , A61B18/1477 , A61B18/1492 , A61B18/24 , A61B90/361 , A61B90/40 , A61B2017/00243 , A61B2017/00247 , A61B2017/00252 , A61B2017/00504 , A61B2017/0641 , A61B2017/0647 , A61B2017/0649 , A61B2017/1107 , A61B2017/1139 , A61B2017/22038 , A61B2017/22077 , A61B2018/00392 , A61B2018/00404 , A61B2018/00869 , A61B2018/1425 , A61B2018/1475 , A61B2090/378 , A61B2090/3925 , A61B2090/3929 , A61B2090/3958 , A61F2/07 , A61F2/2493 , A61F2/90 , A61F2/95 , A61F2/958 , A61F2002/30079 , A61F2002/8486 , A61F2210/009 , A61F2230/001 , A61M2025/0076 , A61M2025/0096 , A61M2025/1052
摘要： This invention is methods and apparatus for connecting two anatomical passageways, such as blood vessels, in side-to-side fashion. Openings are formed in the sidewalls of the passageways, and a connector apparatus (10) of the present invention is implanted within such openings, and extends between the passageways or blood vessels (BV1, BV2) so as to connect the passageways or blood vessels (BV1, BV2) such that the openings are held in direct alignment with one another, thereby allowing body fluids to pass from one passageway into the other.
摘要翻译：本发明是用于连接诸如血管的两个解剖通道的方法和装置。开口形成在通道的侧壁中，并且本发明的连接器装置（10）植入在这些开口内，并且在通道或血管（BV1，BV2）之间延伸，以便连接通道或血管 BV1，BV2），使得开口保持彼此直接对准，从而允许体液从一个通道进入另一个通道。

3. 发明申请

WO1997027893A1 METHODS AND APPARATUS FOR BLOCKING FLOW THROUGH BLOOD VESSELS 审中-公开
标题翻译：通过血管阻塞流动的方法和装置
公开(公告)号：WO1997027893A1
公开(公告)日：1997-08-07
申请号：PCT/US1997001463
申请日：1997-01-31
申请人： TRANSVASCULAR, INC. , EVARD, Philip, C. , FLAHERTY, J., C. , GARIBOTTO, John, T. , MACAULAY, Patrick, E. , MACHOLD, Timothy, R. , MAKOWER, Joshua , WHITT, Jason, B. , JENSEN, Marc
发明人： TRANSVASCULAR, INC.
IPC分类号： A61M19/00
CPC分类号： A61B1/3137 , A61B17/00234 , A61B17/00491 , A61B17/0643 , A61B17/11 , A61B17/12022 , A61B17/12045 , A61B17/12109 , A61B17/12131 , A61B17/12136 , A61B17/12159 , A61B17/12172 , A61B17/12186 , A61B17/1219 , A61B17/3417 , A61B17/3496 , A61B18/00 , A61B18/1445 , A61B18/1477 , A61B18/1492 , A61B18/24 , A61B90/361 , A61B90/40 , A61B2017/00243 , A61B2017/00247 , A61B2017/00252 , A61B2017/00504 , A61B2017/0641 , A61B2017/0647 , A61B2017/0649 , A61B2017/1107 , A61B2017/1139 , A61B2017/1205 , A61B2017/12127 , A61B2017/22038 , A61B2017/22077 , A61B2017/306 , A61B2017/347 , A61B2017/3488 , A61B2018/00392 , A61B2018/00404 , A61B2018/00869 , A61B2018/1425 , A61B2018/1475 , A61B2090/378 , A61B2090/3925 , A61B2090/3929 , A61B2090/3958 , A61F2/07 , A61F2/2493 , A61F2/90 , A61F2/95 , A61F2002/075 , A61F2002/30079 , A61F2002/8486 , A61F2210/009 , A61M2025/0076 , A61M2025/0096 , A61M2025/1052
摘要： This invention is methods and apparatus for occluding blood flow within a blood vessel (22). In a first series of embodiments, the present invention comprises a plurality of embolic devices (16) deployable through the lumen (12) of a conventional catheter (10) such that when deployed, said embolic devices (16) remain resident and occlude blood flow at a specific site within the lumen of the blood vessel (22). Such embolic devices (16) comprise either mechanical embolic devices that become embedded within or compress against the lumen of the vessel or chemical vaso-occlusive agents that seal off blood flow at a given site. A second embodiment of the present invention comprises utilization of a vacuum/cauterizing device capable of sucking in the lumen of the vessel about the device to maintain the vessel in a closed condition where there is then applied a sufficient amount of energy to cause the tissue collapsed about the device to denature into a closure. In a third series of embodiments, the present invention comprises the combination of an embolization facilitator coupled with the application of an energy force to form an intraluminal closure at a specified site within a vessel.
摘要翻译：本发明是用于阻塞血管内血流的方法和装置（22）。在第一系列实施例中，本发明包括可以通过常规导管（10）的内腔（12）展开的多个栓塞装置（16），使得当展开时，所述栓塞装置（16）保持驻留并阻塞血流在血管（22）的内腔内的特定部位。这种栓塞装置（16）包括机械栓塞装置，其将嵌入或挤压在容器的内腔或封闭给定部位的血流的化学血管闭塞剂。本发明的第二个实施方案包括使用能够吸收容器内腔的设备的真空/烧灼装置，以将容器保持在闭合状态，在那里然后施加足够量的能量以使组织折叠关于器件变性成闭合。在第三系列实施方案中，本发明包括栓塞促进剂与施加能量力的组合，以在血管内的指定部位形成腔内闭合。

4. 发明申请

WO1997013471A1 A DEVICE, SYSTEM AND METHOD FOR INTERSTITIAL TRANSVASCULAR INTERVENTION 审中-公开
标题翻译：一种用于间质性转移性干预的装置，系统和方法
公开(公告)号：WO1997013471A1
公开(公告)日：1997-04-17
申请号：PCT/US1996016268
申请日：1996-10-11
申请人： TRANSVASCULAR, INC.
发明人： TRANSVASCULAR, INC. , MAKOWER, Joshua
IPC分类号： A61B19/00
CPC分类号： A61B17/12022 , A61B1/3137 , A61B17/00234 , A61B17/00491 , A61B17/0057 , A61B17/0643 , A61B17/11 , A61B17/12045 , A61B17/12109 , A61B17/12131 , A61B17/12136 , A61B17/12181 , A61B17/1219 , A61B17/320725 , A61B17/3417 , A61B17/3496 , A61B18/00 , A61B18/1445 , A61B18/1477 , A61B18/1492 , A61B18/24 , A61B90/361 , A61B90/40 , A61B2017/00243 , A61B2017/00247 , A61B2017/00252 , A61B2017/003 , A61B2017/00504 , A61B2017/00641 , A61B2017/0641 , A61B2017/1107 , A61B2017/1139 , A61B2017/12127 , A61B2017/22038 , A61B2017/22077 , A61B2017/306 , A61B2017/347 , A61B2017/3488 , A61B2018/00392 , A61B2018/00869 , A61B2018/1425 , A61B2090/378 , A61B2090/3925 , A61B2090/3929 , A61B2090/3958 , A61F2/07 , A61F2/2493 , A61F2/90 , A61F2/95 , A61F2002/30079 , A61F2002/8486 , A61F2210/009 , A61M2025/0076 , A61M2025/018 , A61M2025/1052
摘要： Method and apparatus for utilizing the vascular system as a conduit to reach other vascular and extravascular locations within the body. Included are methods for revascularization wherein the extravascular passageways are formed to permit blood flow between vascular locations. Also included are methods for performing transvascular interstitial surgery (TVIS) wherein extravascular passageways are formed from a blood vessel to another vascular or non-vascular intracorporeal location. Also disclosed are devices usable for forming extravascular passageways in accordance with the invention, or for modifying, valving, maintaining or closing such passageways.
摘要翻译：用于利用血管系统作为导管到达体内其它血管和血管外位置的方法和装置。包括血管重建的方法，其中形成血管外通道以允许血管位置之间的血液流动。还包括执行经血管间质手术（TVIS）的方法，其中血管内通道由血管形成至另一血管或非血管体内位置。还公开了可用于形成根据本发明的血管外通道或用于修改，阀门，维持或关闭这种通道的装置。

5. 发明申请

WO1998016161A1 METHODS AND APPARATUS FOR BYPASSING ARTERIAL OBSTRUCTIONS AND/OR PERFORMING OTHER TRANSVASCULAR PROCEDURES 审中-公开
标题翻译：用于穿过椎间盘手术和/或执行其他横向手术的方法和装置
公开(公告)号：WO1998016161A1
公开(公告)日：1998-04-23
申请号：PCT/US1996019093
申请日：1996-11-27
申请人： TRANSVASCULAR, INC.
发明人： TRANSVASCULAR, INC. , EVARD, Philip, C. , FLAHERTY, J., C. , GARIBOTTO, John, T. , MACAULAY, Patrick, E. , MACHOLD, Timothy, R. , MAKOWER, Joshua , WHITT, Jason, B. , VIDAL, Clade, A. , REDMOND, Russel, J. , BANKS, Thomas
IPC分类号： A61B17/36
CPC分类号： A61B17/3417 , A61B17/00491 , A61B17/0643 , A61B17/11 , A61B17/12022 , A61B17/12045 , A61B17/12109 , A61B17/12136 , A61B18/00 , A61B18/1477 , A61B18/1492 , A61B90/40 , A61B2017/00243 , A61B2017/00247 , A61B2017/00252 , A61B2017/00504 , A61B2017/1107 , A61B2017/1139 , A61B2017/12127 , A61B2017/306 , A61B2017/347 , A61B2018/00392 , A61B2018/1425 , A61F2/2493 , A61F2002/30079 , A61F2210/009 , A61M2025/0076 , A61M2025/009 , A61M2025/1052
摘要： This invention concerns methods, devices, and systems for re-vascularization, and/or performing other medical procedures at vascular or non-vascular intra-corporeal locations within a mammalian body. The methods generally comprise the formation of at least one extravascular passageway (10a) from a blood vessel to a vascular or non-vascular target location. In the re-vascularization methods the extravascular passageway is utilized for blood flow. In the medical procedure methods the extravascular passageway (10a) is utilized as a conduit for accessing or performing procedures at the vascular or non-vascular target location. Also disclosed are catheter devices and systems which are useable to form the extravascular passageways (10a, 10b) of the invention, as well as apparatus for modifying, maintaining and/or closing such extravascular passageways.
摘要翻译：本发明涉及在哺乳动物体内的血管或非血管内体内再次血管化和/或执行其它医学过程的方法，装置和系统。所述方法通常包括从血管到血管或非血管目标位置形成至少一个血管外通道（10a）。在再血管化方法中，血管外通路用于血流。在医疗程序方法中，血管外通路（10a）用作在血管或非血管目标位置处进入或执行手术的导管。还公开了可用于形成本发明的血管外通道（10a，10b）的导管装置和系统，以及用于修改，维持和/或关闭这种血管外通道的装置。

6. 发明申请

WO1997013463A1 METHODS AND APPARATUS FOR BYPASSING ARTERIAL OBSTRUCTIONS AND/OR PERFORMING OTHER TRANSVASCULAR PROCEDURES 审中-公开
标题翻译：用于穿过椎间盘手术和/或执行其他横向手术的方法和装置
公开(公告)号：WO1997013463A1
公开(公告)日：1997-04-17
申请号：PCT/US1996016483
申请日：1996-10-11
申请人： TRANSVASCULAR, INC.
发明人： TRANSVASCULAR, INC. , EVARD, Philip, C. , FLAHERTY, J., C. , GARIBOTTO, John, T. , MACAULAY, Patrick, E. , MACHOLD, Timothy, R. , MAKOWER, Joshua , WHITT, Jason, B. , VIDAL, Clade, A. , REDMOND, Russel, J. , BANKS, Thomas
IPC分类号： A61B17/00
CPC分类号： A61B1/3137 , A61B17/00234 , A61B17/00491 , A61B17/0057 , A61B17/0643 , A61B17/11 , A61B17/12022 , A61B17/12045 , A61B17/12109 , A61B17/12131 , A61B17/12136 , A61B17/320725 , A61B17/3417 , A61B17/3496 , A61B18/00 , A61B18/1445 , A61B18/1477 , A61B18/1492 , A61B18/24 , A61B90/361 , A61B90/40 , A61B2017/00243 , A61B2017/00247 , A61B2017/00252 , A61B2017/003 , A61B2017/00331 , A61B2017/00504 , A61B2017/00637 , A61B2017/00668 , A61B2017/0641 , A61B2017/1107 , A61B2017/1139 , A61B2017/12127 , A61B2017/22038 , A61B2017/22077 , A61B2017/22095 , A61B2017/306 , A61B2017/347 , A61B2017/3488 , A61B2018/00392 , A61B2018/00404 , A61B2018/00869 , A61B2018/1425 , A61B2018/1475 , A61B2090/378 , A61B2090/3925 , A61B2090/3929 , A61B2090/3958 , A61F2/07 , A61F2/2493 , A61F2/90 , A61F2/95 , A61F2002/30079 , A61F2002/8486 , A61F2210/009 , A61M2025/0076 , A61M2025/0096 , A61M2025/018 , A61M2025/1052
摘要： This invention is methods, devices, and systems for re-vascularization, and/or performing other medical procedures at a vascular or non-vascular intra-corporeal locations within a mammalian body. The methods generally comprise the formation of at least one extravascular passageway from a blood vessel to a vascular or non-vascular target location. In the re-vascularization methods the extravascular passageway is utilized as a conduit for accessing or performing procedures at the vascular or non-vascular target location. Also disclosed are catheter devices (100, 103) and systems (138) which are usable to form the extravascular passageways of the invention, as well as apparatus for modifying, maintaining and/or closing such extravascular passageways.
摘要翻译：本发明是在哺乳动物体内的血管或非血管内体内位置进行再血管化和/或执行其它医学过程的方法，装置和系统。所述方法通常包括从血管到血管或非血管目标位置形成至少一个血管内通道。在再血管化方法中，血管外通路被用作在血管或非血管目标位置进入或执行手术的导管。还公开了可用于形成本发明的血管外通道的导管装置（100,103）和系统（138），以及用于修改，维持和/或关闭这种血管外通道的装置。

7. 发明申请

WO1998008456A1 METHODS AND APPARATUS FOR TRANSMYOCARDIAL DIRECT CORONARY REVASCULARIZATION 审中-公开
标题翻译：转移性直接冠状动脉再狭窄的方法和装置
公开(公告)号：WO1998008456A1
公开(公告)日：1998-03-05
申请号：PCT/US1997014801
申请日：1997-08-25
申请人： TRANSVASCULAR, INC.
发明人： TRANSVASCULAR, INC. , MAKOWER, Joshua , MACHOLD, Timothy , FLAHERTY, Christopher, J. , WHITT, Jason, Brian
IPC分类号： A61B19/00
CPC分类号： A61F2/94 , A61B2017/00247 , A61B2017/00252 , A61B2018/00392 , A61F2/07 , A61F2/2412 , A61F2/2493 , A61F2220/0008
摘要： This invention is methods and apparatus for direct coronary revascularization wherein a transmyocardial passageway (10) is formed between a chamber of the heart (LV) and a coronary blood vessel (CBV) to permit blood to flow therebetween. In some embodiments, the transmyocardial passageway (10) is formed between a chamber of the heart (LV) and a coronary vein (CV). The invention includes unstent transmyocardial passageways (10), as well as transmyocardial passageways (10) wherein protrusive stent devices (90) extend from the transmyocardial passageway (10) into an adjacent coronary vessel (CBV) or chamber of the heart (LV). The apparatus of the present invention includes protrusive stent devices (90) for stent of transmyocardial passageways (10), intraluminal valve devices (40) for valving of transmyocardial passageways (10), intra-cardiac valve devices (80) for valving of transmyocardial passageways (10), endogenous tissue valves (50) for valving of transmyocardial passageways (10), and ancillary apparatus for use in conjunction therewith.
摘要翻译：本发明是用于直接冠状动脉血运重建的方法和装置，其中在心脏室（LV）和冠状血管（CBV）之间形成经心肌通路（10），以允许血液在其间流动。在一些实施例中，经心肌通路（10）形成在心脏室（LV）和冠状静脉（CV）之间。本发明包括不稳定的经心肌通道（10）以及其中突出的支架装置（90）从心肌通路（10）延伸到相邻的冠状血管（CBV）或心脏室（LV）的经心肌通道（10）。本发明的装置包括用于经心肌通路（10）的支架的突出支架装置（90），用于跨心肌通道（10）阀门的腔内阀装置（40），用于跨心肌通道阀的心脏内瓣膜装置（80）（10），用于经心肌通道（10）的阀门的内源性组织瓣膜（50）以及与其结合使用的辅助装置。

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