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1. 发明申请

WO2017083753A1 COMPOSITIONS AND METHODS FOR VAS-OCCLUSIVE CONTRACEPTION AND REVERSAL THEREOF 审中-公开
标题翻译： VAS闭塞性收缩的组合物和方法及其逆转
公开(公告)号：WO2017083753A1
公开(公告)日：2017-05-18
申请号：PCT/US2016/061671
申请日：2016-11-11
申请人： HERR, John C. , KLIBANOV, Alexander L. , EISENFRATS, Kevin Simon
发明人： HERR, John C. , KLIBANOV, Alexander L. , EISENFRATS, Kevin Simon
IPC分类号： A61F6/00 , A61F6/02 , A61F6/20 , A61F6/22
CPC分类号： A61L24/06 , A61B8/0833 , A61B8/0841 , A61B8/085 , A61B8/0891 , A61B8/481 , A61B8/488 , A61B17/12 , A61B17/12022 , A61B17/12186 , A61B17/3403 , A61B2017/3413 , A61F6/22 , A61K49/223 , A61K49/226 , A61L24/001 , A61L24/0015 , A61L24/0031 , A61L24/0036 , A61L27/52 , A61L27/54 , A61L2300/626 , A61L2400/06 , A61L2430/36
摘要： Disclosed are methods of delivering an agent to the lumen of the vas deferens under guidance of ultrasound imaging. The methods include vas-occlusive contraception in which the vas deferens is non-surgically isolated and an occlusive substance is percutaneously administered into the lumen of the vas deferens under ultrasound. Also disclosed are methods of reversal of vas-occlusive contraception and methods of delivering an agent to the lumen of the vas deferens. Also disclosed are compositions for use in the methods of the invention.
摘要翻译：公开了在超声成像的指导下将药剂递送至输精管腔的方法。该方法包括输精管避孕法，其中输精管是非手术分离的，并且在超声下经皮输入闭合物质到输精管腔中。还公开了逆转血管闭塞避孕的方法和将药剂递送至输精管腔的方法。还公开了用于本发明方法的组合物。

2. 发明申请

WO2016154633A1 SYSTEMS AND METHODS FOR VASCULAR OCCLUSION 审中-公开
标题翻译：用于血管闭塞的系统和方法
公开(公告)号：WO2016154633A1
公开(公告)日：2016-09-29
申请号：PCT/US2016/024584
申请日：2016-03-28
申请人： BOSTON SCIENTIFIC SCIMED, INC. , SQUIRE, Robert , MUNSINGER, Joel , LARSON, Derek , WILLARD, Martin , CONNOLLY, Joseph
发明人： SQUIRE, Robert , MUNSINGER, Joel , LARSON, Derek , WILLARD, Martin , CONNOLLY, Joseph
IPC分类号： A61B17/12 , A61B17/42
CPC分类号： A61B17/12172 , A61B17/12022 , A61B17/12109 , A61B17/12113 , A61B17/12186 , A61B2017/00867 , A61B2017/1205 , A61B2017/12054 , A61B2017/4216 , A61B2090/3966
摘要： Expandable occlusive plugs and methods of using them are disclosed. The devices generally include an expandable framework at least partially covered by a membrane. The occlusive plugs can be used for occlusion of body lumens and/or to limit migration of embolic agents to non-target sites.
摘要翻译：公开了可扩展闭塞插头及其使用方法。这些装置通常包括至少部分被膜覆盖的可膨胀框架。闭塞塞可用于闭合体腔和/或限制栓塞剂向非靶位点的迁移。

3. 发明申请

WO2016154632A1 EMBOLIC COIL DELIVERY SYSTEM WITH EASY-RELEASE KNOT 审中-公开
标题翻译：具有易于释放的手套的嵌入式线圈输送系统
公开(公告)号：WO2016154632A1
公开(公告)日：2016-09-29
申请号：PCT/US2016/024581
申请日：2016-03-28
申请人： BOSTON SCIENTIFIC SCIMED, INC. , ANDERSON, Mary-Claire , TASSONI, Nicholas , GUPTA, Ajay
发明人： ANDERSON, Mary-Claire , TASSONI, Nicholas , GUPTA, Ajay
IPC分类号： A61B17/12
CPC分类号： A61B17/1214 , A61B17/12022 , A61B17/12031 , A61B17/12036 , A61B17/12109 , A61B2017/00867 , A61B2017/12054
摘要： The present disclosure relates to the field of embolic coil delivery. In particular, the present disclosure provides a delivery system that allows an embolic coil, retained on a delivery tube outside of the microcatheter, to be positioned within a target occlusion area of a patient prior to being controllably deployed, or retracted into the microcatheter for repositioning. The delivery system is particularly useful for minimizing embolic coil kickback.
摘要翻译：本发明涉及栓塞线圈输送领域。特别地，本公开提供了一种输送系统，其允许保持在微导管外部的输送管上的栓塞线圈在被可控地展开之前被定位在患者的目标闭塞区域内，或者缩回到微导管中用于重新定位。输送系统对于最小化栓塞线圈反冲特别有用。

4. 发明申请

WO2016041961A2 AN EMBOLISATION DEVICE 审中-公开
标题翻译：一种栓塞装置
公开(公告)号：WO2016041961A2
公开(公告)日：2016-03-24
申请号：PCT/EP2015071097
申请日：2015-09-15
申请人： NAT UNIV IRELAND
发明人： MULLINS LIAM , FORDE COLIN , ALLEN WAYNE , SHERIDAN WILLIAM , GILSON PAUL
IPC分类号： A61B17/12
CPC分类号： A61B17/12022 , A61B17/12031 , A61B17/12109 , A61B17/1215 , A61B17/12163 , A61B17/12177 , A61B2017/00526 , A61B2017/00867 , A61B2017/00995 , A61B2017/1205 , A61B2017/12095
摘要： An embolisation device for promoting clot formation in a lumen comprises at least two segments (3,4), each segment (3,4) comprising a stem and a plurality of flexible bristles extending outwardly from the stem. The bristles have a contracted delivery configuration and a deployed configuration in which the bristles extend generally radially outwardly from the stem to anchor the device in a lumen. In the deployed configuration bristles of one segment (3) extend partially in a first longitudinal direction and the bristles of another segment (4) extend partially in a second longitudinal direction which is opposite to the first longitudinal direction. A flow restrictor (5) is located adjacent to a proximal end of the device and/or a flow restrictor (5') is located adjacent to the distal end of the device.
摘要翻译：一种用于促进管腔中凝块形成的栓塞装置，包括至少两个区段（3,4），每个区段（3,4）包括一个杆和多个从杆向外延伸的柔性刷毛。刷毛具有收缩的输送构型和展开构型，其中刷毛从杆通常径向向外延伸以将装置锚定在内腔中。在展开构型中，一个区段（3）的刷毛部分地沿第一纵向方向延伸，并且另一个区段（4）的刷毛部分地沿与第一纵向方向相反的第二纵向方向延伸。限流器（5）位于装置的近端附近和/或限流器（5'）位于装置的远端附近。

5. 发明申请

WO2015168501A3 OCCLUDER AND ANASTOMOSIS DEVICES 审中-公开
标题翻译：监护人和解剖装置
公开(公告)号：WO2015168501A3
公开(公告)日：2015-12-17
申请号：PCT/US2015028707
申请日：2015-05-01
申请人： GORE & ASS
发明人： JOHNSON MATTHEW A , MOONEY NATHAN K , MICHALAK CHRISTOPHER S
IPC分类号： A61B17/11 , A61B17/12
CPC分类号： A61B17/0057 , A61B17/11 , A61B17/1114 , A61B17/12022 , A61B17/12031 , A61B17/12099 , A61B17/12145 , A61B2017/00592 , A61B2017/00597 , A61B2017/00615 , A61B2017/00623 , A61B2017/00632 , A61B2017/00676 , A61B2017/00818 , A61B2017/00867 , A61B2017/1103 , A61B2017/1139 , A61B2017/1205
摘要： An implantable medical device for sealing and repairing defects in a body tissue or for creating an anastomosis includes a frame (1000, 100, 1410, 1610, 1810, 1910, 191, 1, 2210, 2310, 400, 700) and a covering material (1110, 1412, 1612, 1812, 1912, 210, 2214, 2314, 510, 810). In some embodiments, the frame (1000, 100, 1410, 1610, 1810, 1910, 191, 1, 2210, 2310, 400, 700) includes a single continuously wound wire that defines an apposition portion (1020, 120, 130, 1420, 1820, 1920, 1, 420, 720), a defect-occupying portion, and a sealing portion (1030, 130, 1430, 1830, 1930, 430, 730). In some embodiments, the tissue-sealing and anastomosis devices provided herein are well-suited for use in the Gl tract including the small bowel and colon. In some embodiments, a two-part frame (1000, 100, 1410, 1610, 1810, 1910, 191, 1, 2210, 2310, 400, 700) construct facilitates independent tailoring of apposition forces and radial forces exerted on tissues by the two-part frame (1000, 100, 1410, 1610, 1810, 1910, 191, 1, 2210, 2310, 400, 700)
摘要翻译：用于密封和修复身体组织中的缺陷或用于产生吻合的可植入医疗装置包括框架（1000,100,11010,1610,1810,1910,191,1,210,2310,400,700）和覆盖材料（1110,1412,1612,1812,1912,210,2214,2134,510,810）。在一些实施例中，框架（1000,100,410,1610,1810,191,191,1610,1810,191,191,1610,1810,191,191,1610,1810,191,191,1610,1810,1910,191,1,21010,21010,700,700）包括单个连续卷绕的线，其限定了一个安置部分（1020,120,130,1420 ，1820,1920,1202,720），缺陷占据部分和密封部分（1030,130,1430,1830,1930,430,730）。在一些实施例中，本文提供的组织密封和吻合装置非常适合用于包括小肠和结肠的GI系。在一些实施例中，两部分框架（1000,100,410,1610,1810,1910,191,1610,1810,1910,191,1,210,2310,400,700）构造有助于独立调整由两者施加在组织上的叠合力和径向力 - 第一帧（1000,100,14010,1610,1810,1910,191,1,21010,2310,400,700）

6. 发明申请

WO2015134917A3 IMPLANTABLE MEDICAL DEVICE CONSTRAINT AND DEPLOYMENT APPARATUS 审中-公开
标题翻译：可植入医疗器械约束和部署装置
公开(公告)号：WO2015134917A3
公开(公告)日：2015-12-03
申请号：PCT/US2015019271
申请日：2015-03-06
申请人： GORE & ASS
发明人： IRWIN CRAIG W , SILVERMAN JAMES D
IPC分类号： A61F2/95 , A61F2/962
CPC分类号： A61F2/95 , A61B17/12022 , A61B2017/12054 , A61F2/962 , A61F2/966 , A61F2002/9517 , A61F2002/9522 , A61F2250/0067 , Y10T29/49872
摘要： An implantable medical device deployment system is disclosed that employs both a sheath element (26) and a constraint member (32) to protect implantable medical devices during delivery in a body while providing simple, accurate, and reliable device deployment. The delivery system is configured so that loading and deployment forces are not directly related to device diameter, length, or design, thus allowing a more universal delivery system across various delivered device configurations and product lines. The deployment system can provide numerous benefits, include better protection for drug-coated implantable devices.
摘要翻译：公开了一种植入式医疗装置展开系统，其采用护套元件（26）和约束构件（32），以在输送体内保护可植入医疗装置，同时提供简单，准确和可靠的装置部署。配送系统被配置成使得装载和展开力与设备的直径，长度或设计没有直接关系，从而允许跨越各种传送的设备配置和产品线的更通用的传送系统。部署系统可以提供许多好处，包括对药物涂层可植入装置的更好保护。

7. 发明申请

WO2014210280A3 MEDICAL DEVICE DEPLOYMENT SYSTEM 审中-公开
标题翻译：医疗器械部署系统
公开(公告)号：WO2014210280A3
公开(公告)日：2015-03-26
申请号：PCT/US2014044288
申请日：2014-06-26
申请人： GORE & ASS
发明人： CHOUINARD BRIAN D , FRIEDMAN NATHAN L , LOPEZ JOSUE , MCDANIEL THOMAS R , ZUKOWSKI STANISLAW L
IPC分类号： A61B17/12
CPC分类号： A61B17/12022 , A61B17/12145 , A61B17/12168 , A61B2017/00575 , A61B2017/12054
摘要： Deployment systems and methods are provided herein for percutaneous transcatheter deployment of medical devices. A medical device deployment system includes a body member and a body locking member that is configured to cooperatively engage along a portion of the body member such that the body member is releasably coupleable to a medical device.
摘要翻译：本文提供了用于经皮经导管部署医疗装置的部署系统和方法。医疗装置展开系统包括主体构件和主体锁定构件，其构造成沿主体构件的一部分协作地接合，使得主体构件可释放地联接到医疗装置。

8. 发明申请

WO2014152579A1 INTERFERENCE-RELIEF TYPE DELIVERY DETACHMENT SYSTEMS 审中-公开
标题翻译：干扰减免类型交付分离系统
公开(公告)号：WO2014152579A1
公开(公告)日：2014-09-25
申请号：PCT/US2014/027495
申请日：2014-03-14
申请人： COVIDIEN LP
发明人： HALDEN, Karl, S. , DEBEER, Nicholas, C. , BECKING, Frank, P.
IPC分类号： A61B17/12 , A61F2/95
CPC分类号： A61F2/06 , A61B17/0057 , A61B17/12022 , A61B17/12109 , A61B17/12113 , A61B17/12172 , A61B90/39 , A61B2017/12054
摘要： Various features are described that are adapted to improve performance of interference-relief type delivery systems. A delivery system provided herein comprises an implant comprising a socket at a proximal end of the implant; an elongate sleeve having (i) a proximal section, (ii) a distal section slidably disposed within the socket, and (iii) a window between the proximal section and the distal section, the window extending through a wall of the sleeve; and a core member having a proximal portion slidably received within the proximal section of the sleeve and a distal portion extending through the window to a space outside the sleeve and within the socket. The distal portion of the core member provides an interference fit with the distal section of the sleeve within the socket until the core member is withdrawn.
摘要翻译：描述了适于提高干扰减轻型输送系统的性能的各种特征。本文提供的递送系统包括在植入物的近端处包括插座的植入物; 细长的套筒，其具有（i）近端部分，（ii）可滑动地设置在所述插座内的远侧部分，以及（iii）所述近端部分和所述远端部分之间的窗口，所述窗口延伸穿过所述套筒的壁; 以及芯构件，其具有可滑动地容纳在所述套筒的近侧部分内的近端部分和远离所述窗口延伸到所述套筒外部且在所述插座内的空间的远端部分。芯构件的远端部分提供与插座内的套筒的远端部分的过盈配合，直到芯构件被拉出。

9. 发明申请

WO2014078458A2 OCCLUSIVE DEVICES 审中-公开
标题翻译： OCCLUSIVE设备
公开(公告)号：WO2014078458A2
公开(公告)日：2014-05-22
申请号：PCT/US2013/069955
申请日：2013-11-13
申请人： COVIDIEN LP
发明人： DIVINO, Vincent , BARDSLEY, Earl Frederick , RHEE, Richard , KADAM, Madhur Arunrao , KULAK, Julie
IPC分类号： A61B17/12
CPC分类号： A61B17/12113 , A61B17/12022 , A61B17/12118 , A61B17/12159 , A61B17/12163 , A61B17/12186 , A61B17/1219 , A61B2017/1205 , A61F2/95
摘要： A system for treatment of an aneurysm includes an intrasaccular device that can be delivered using a catheter. The device can include at least one expandable structure adapted to transition from a compressed configuration to an expanded configuration when released into the aneurysm. The expandable structure can have a specific shape or porosity. Multiple expandable structures can also be used, in which case each of the expandable structures can have a unique shape or porosity profile. The morphology of the aneurysm and orientation of any connecting arteries can determine the type, size, shape, number, and porosity profile of the expandable structure used in treating the aneurysm.
摘要翻译：用于治疗动脉瘤的系统包括可以使用导管递送的囊内装置。该装置可以包括至少一个可释放结构，其适于在释放到动脉瘤中时从压缩构型转变成扩张构型。可膨胀结构可以具有特定的形状或多孔性。也可以使用多个可膨胀结构，在这种情况下，每个可膨胀结构可以具有独特的形状或孔隙率分布。动脉瘤的形态和任何连接动脉的取向可以确定用于治疗动脉瘤的可扩张结构的类型，大小，形状，数量和孔隙率。

10. 发明申请

WO2014022866A1 DEVICES AND METHODS FOR TREATING OCCLUSION OF THE OPHTHALMIC ARTERY 审中-公开
标题翻译：用于治疗眼科手术的装置和方法
公开(公告)号：WO2014022866A1
公开(公告)日：2014-02-06
申请号：PCT/US2013/053670
申请日：2013-08-05
申请人： J.D. FRANCO & COMPANY , FRANCO, Jeff , CALHOUN, Michael
发明人： FRANCO, Jeff , CALHOUN, Michael
IPC分类号： A61F2/14 , A61F2/06 , A61F2/02
CPC分类号： A61F9/00736 , A61B3/16 , A61B17/12022 , A61B17/221 , A61B17/320725 , A61B2017/22002 , A61B2017/22067 , A61B2017/22079 , A61F2/013 , A61F2/02 , A61F2/06 , A61F9/00781 , A61F9/008 , A61F2002/018 , A61M25/104 , A61M2210/0612 , A61M2210/12
摘要： There is provided herein a disclosure and specification of invention(s) relating to devices and methods for percutaneous access and treatment of vascular structures in the rear of the eye, including treatment for the symptoms related to Wet Age Related Macular Degeneration by removal of stenosis of the OA, thereby restoring normal, or near normal, blood flow to the rear of the eye, including the retina and associated structures. Also provided herein is a disclosure and specification of invention(s) relating to methods and devices for selective manipulation of Intraocular Pressure (IOP) be means of mechanical force for the purpose of inducing retrograde flow in the ophthalmic vasculature.
摘要翻译：本文提供了关于用于经皮进入和治疗眼后部血管结构的装置和方法的发明的公开和说明书，包括通过去除狭窄的湿疣相关性黄斑变性的相关症状的治疗 OA，从而恢复正常或接近正常的血液流到眼睛的后部，包括视网膜和相关结构。本文还提供了关于用于选择性操纵眼内压（IOP）的方法和装置的发明的公开和说明书是用于在眼科脉管系统中诱发逆行流动的机械力的手段。

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