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1. 发明申请

WO2012058682A1 SELECTIVE TISSUE REMOVAL TOOL FOR USE IN MEDICAL APPLICATIONS AND METHODS FOR MAKING AND USING 审中-公开
标题翻译：用于医疗应用的选择性组织移除工具及其制造和使用方法
公开(公告)号：WO2012058682A1
公开(公告)日：2012-05-03
申请号：PCT/US2011/058635
申请日：2011-10-31
申请人： MICROFABRICA INC. , SCHMITZ, Gregory, P. , MILLER, Eric, C. , CHEN, Richard, T. , WU, Ming, T.
发明人： SCHMITZ, Gregory, P. , MILLER, Eric, C. , CHEN, Richard, T. , WU, Ming, T.
IPC分类号： A61B17/50
CPC分类号： A61B17/3205 , A61B17/00234 , A61B17/16 , A61B17/1671 , A61B17/22031 , A61B17/221 , A61B17/32002 , A61B90/361 , A61B2017/00261 , A61B2017/003 , A61B2017/00553 , A61B2017/1602 , A61B2017/22039 , A61B2017/22044 , A61B2017/22077 , A61B2017/2927 , A61B2017/320048 , A61B2017/320775 , A61M1/0056 , A61M2210/1025 , A61M2210/1042
摘要： The present disclosure relates generally to the field of tissue removal and more particularly to methods and devices for use in medical applications involving selective tissue removal. One exemplary method includes the steps of providing a tissue cutting instrument capable of distinguishing between target tissue to be removed and non- target tissue, urging the instrument against the target tissue and the non-target tissue, and allowing the instrument to cut the target tissue while automatically avoiding cutting of non-target tissue. Various tools for carrying out this method are also described.
摘要翻译：本公开一般涉及组织去除领域，更具体地涉及用于涉及选择性组织去除的医学应用中的方法和装置。一个示例性方法包括以下步骤：提供能够区分要移除的目标组织和非目标组织的组织切割仪器，将仪器推向目标组织和非目标组织，并允许仪器切割靶组织同时自动避免切割非目标组织。还描述了用于执行该方法的各种工具。

2. 发明申请

WO2011106735A1 SYSTEMS AND METHODS FOR ENDOLUMINAL VALVE CREATION 审中-公开
标题翻译：用于内膜瓣创建的系统和方法
公开(公告)号：WO2011106735A1
公开(公告)日：2011-09-01
申请号：PCT/US2011/026370
申请日：2011-02-25
申请人： THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY , WILSON, Fletcher T. , YU, Rhunjay James , AFSHAR, Pedram , RAY, Partha P.
发明人： WILSON, Fletcher T. , YU, Rhunjay James , AFSHAR, Pedram , RAY, Partha P.
IPC分类号： A61M25/01
CPC分类号： A61B90/02 , A61B17/0644 , A61B17/22031 , A61B17/320016 , A61B17/3203 , A61B17/320783 , A61B17/3209 , A61B2017/00783 , A61B2017/00867 , A61B2017/22052 , A61B2017/22069 , A61B2017/22071 , A61B2017/22077 , A61B2017/22095 , A61B2017/306 , A61B2017/320044 , A61B2017/320048 , A61B2017/320056 , A61B2017/32006 , A61B2017/320064 , A61B2017/320741 , A61M25/0147 , A61M25/1002 , A61M2025/1047
摘要： A device for manipulating tissue at a vessel includes an elongated member having a proximal end and a distal end, a guide member at the distal end of the elongated member, the guide member having a blunt distal tip for engagement against an interior wall of the vessel, and a tissue cutting device at the distal end of the elongated member, wherein the tissue cutting device has a sharp tip that is proximal to the blunt distal tip of the guide member.
摘要翻译：用于在容器处操作组织的装置包括具有近端和远端的细长构件，在细长构件的远端处的引导构件，引导构件具有用于与容器的内壁接合的钝的远端，以及在所述细长构件的远端处的组织切割装置，其中所述组织切割装置具有靠近所述引导构件的钝的远侧末端的尖端。

3. 发明申请

WO2008070262B1 APPARATUS AND METHOD FOR TARGETING A BODY TISSUE 审中-公开
标题翻译：装置和方法来达到身体组织
公开(公告)号：WO2008070262B1
公开(公告)日：2008-12-04
申请号：PCT/US2007080516
申请日：2007-10-05
申请人： CLEVELAND CLINIC FOUNDATION
发明人： KAPADIA SAMIR
IPC分类号： A61B17/34
CPC分类号： A61B17/3478 , A61B34/20 , A61B2017/00243 , A61B2017/00247 , A61B2017/00252 , A61B2017/00278 , A61B2017/22038 , A61B2017/22077 , A61B2017/22095 , A61B2017/3484 , A61B2018/00392 , A61B2090/3929 , A61B2090/3958 , A61N1/06
摘要： An apparatus for targeting a desired target site on a body tissue that separates a first body cavity from a second body cavity of a patient includes a catheter having a longitudinally extending catheter lumen and adapted to provide access to the first body cavity. A framing member has a collapsed condition in which the framing member is adapted for insertion into the first body cavity through the catheter lumen and an expanded condition in which the framing member is adapted for placement within the first body cavity. At least one target point is carried by the framing member and is adapted for placement adjacent the body tissue to indicate the desired target site. A method of using the apparatus is also described.
摘要翻译：用于对准将第一体腔与患者的第二体腔分离的身体组织上的期望目标部位的装置包括具有纵向延伸的导管内腔并适于提供对第一体腔的通路的导管。框架构件具有折叠状态，其中框架构件适于通过导管腔插入第一体腔中，并且扩张状态，其中框架构件适于放置在第一体腔内。至少一个目标点由框架构件承载并且适于邻近身体组织放置以指示期望的目标位置。还描述了使用该装置的方法。

4. 发明申请

WO2005044079A2 APPARATUS AND METHOD FOR ENDOSCOPIC CARDIAC MAPPING AND LEAD PLACEMENT 审中-公开
标题翻译：用于内镜心脏图谱和引导放置的装置和方法
公开(公告)号：WO2005044079A2
公开(公告)日：2005-05-19
申请号：PCT/US2004/034538
申请日：2004-10-19
申请人： ORIGIN MEDSYSTEMS, INC. , CHIN, Albert, K. , DAVIS, John , WESTLUND, Randy
发明人： CHIN, Albert, K. , DAVIS, John , WESTLUND, Randy
IPC分类号： A61B
CPC分类号： A61B17/3421 , A61B1/00094 , A61B17/00008 , A61B17/320068 , A61B17/3403 , A61B17/3417 , A61B17/3468 , A61B17/3478 , A61B18/1482 , A61B90/11 , A61B90/39 , A61B2017/00243 , A61B2017/00247 , A61B2017/061 , A61B2017/22077 , A61B2017/306 , A61B2017/308 , A61B2017/320044 , A61B2017/3445 , A61B2017/3488 , A61B2018/00291 , A61B2018/00392 , A61B2018/00982 , A61B2090/036 , A61B2090/062
摘要： Apparatus and surgical methods establish temporary suction attachment to a target site on the surface of a beating heart for analyzing electrical signals or hemodynamic responses to applied signals at the target sites for enhancing the accuracy of placement of cardiac electrodes at selected sites and for enhancing accurate placement of a surgical instrument maintained in alignment with the suction attachment. A suction port on the distal end of a supporting cannula carries surface-contacting electrodes and provides suction attachment to facilitate temporary positioning of the electrodes in contact with tissue at the target site, and a clamping and release mechanism to facilitate anchoring a cardiac electrode on the moving surface of a beating heart at a selected site. Analyses of sensed signals or responses to applied signals at target sites promote epicardial mapping of a patient's heart for determining optimum sites at which to attach cardiac electrodes.
摘要翻译：装置和手术方法建立临时抽吸附着到跳动心脏表面上的目标部位，用于分析电信号或对目标部位施加的信号的血液动力学反应，以提高心脏电极在选定部位的放置准确度，并提高准确放置保持与抽吸附件对齐的手术器械。在支撑套管的远端上的吸入口携带表面接触电极并且提供吸附附件，以便于电极与目标部位的组织接触的临时定位，以及夹持和释放机构，以便于将心电极固定在跳动心脏在选定的地点的移动表面。感测信号的分析或对目标位置的应用信号的响应促进患者心脏的心外膜映射，以确定附着心脏电极的最佳位置。

5. 发明申请

WO2004028233A3 METHODS AND DEVICES FOR ABLATION 审中-公开
标题翻译：用于排除的方法和装置
公开(公告)号：WO2004028233A3
公开(公告)日：2004-06-24
申请号：PCT/US0330163
申请日：2003-09-23
申请人： EPICOR MEDICAL INC , VASKA MATTHIAS , CROWE JOHN E , MILLER GARY HENRY , PODMORE JONATHAN , CHAMPSAUR GERARD , HOFFMAN DREW , TANSEY CASEY
发明人： VASKA MATTHIAS , CROWE JOHN E , MILLER GARY HENRY , PODMORE JONATHAN , CHAMPSAUR GERARD , HOFFMAN DREW , TANSEY CASEY
IPC分类号： A61B5/042 , A61B17/00 , A61B17/22 , A61B17/34 , A61B18/00 , A61B18/02 , A61B18/14 , A61B18/18 , A61B19/00 , A61M25/14 , A61N1/06 , A61N1/362 , A61N7/02
CPC分类号： A61B17/22012 , A61B5/0422 , A61B17/2202 , A61B17/2251 , A61B18/00 , A61B18/02 , A61B18/1402 , A61B18/148 , A61B18/1482 , A61B18/1492 , A61B34/20 , A61B2017/00243 , A61B2017/00247 , A61B2017/00252 , A61B2017/003 , A61B2017/22077 , A61B2017/2253 , A61B2017/3419 , A61B2018/00023 , A61B2018/0016 , A61B2018/00232 , A61B2018/00261 , A61B2018/00285 , A61B2018/00291 , A61B2018/00351 , A61B2018/00363 , A61B2018/00375 , A61B2018/00392 , A61B2018/00577 , A61B2018/00654 , A61B2018/00797 , A61B2018/00839 , A61B2018/142 , A61B2018/1467 , A61B2018/1472 , A61B2090/3614 , A61B2090/3782 , A61B2090/395 , A61B2218/002 , A61B2218/007 , A61M25/0041 , A61M25/0084 , A61M25/04 , A61M25/1002 , A61M25/1011 , A61M2025/0293 , A61M2025/1072 , A61N1/06 , A61N1/362 , A61N7/02
摘要： An ablating device and method. The method includes providing an ablating device (38) having a plurality of ultrasound ablating elements (76) into an epicardal space, directing ultrasound energy at a first frequency for a first plurality of time periods, and directing ultrasound energy for a second plurality of time periods. Also, devices and methods for measuring a cardiac ablation length, and a device a movable cover with a flowable substance are disclosed.
摘要翻译：一种消融装置和方法。该方法包括提供具有多个超声消融元件（76）的消融装置（38）进入心外膜空间，将第一频率的超声能量引导第一多个时间段，以及将超声能量引导第二多个时间周期。此外，公开了用于测量心脏消融长度的装置和方法，以及具有可流动物质的可移动盖的装置。

6. 发明申请

WO2004030740A1 FLEXIBLE POLYMER NEEDLE CATHETER 审中-公开
标题翻译：柔性聚合物针导管
公开(公告)号：WO2004030740A1
公开(公告)日：2004-04-15
申请号：PCT/US2003/030464
申请日：2003-09-26
申请人： ADVANCED CARDIOVASCULAR SYSTEMS, INC.
发明人： GONZALEZ, Fernando , WEBLER, William, E.
IPC分类号： A61M25/00
CPC分类号： A61B17/3478 , A61B2017/00247 , A61B2017/22077 , A61B2018/00392 , A61M2025/0086 , A61M2025/0089
摘要： A catheter device having an elongated tubular member with a proximal end and a distal end, and a needle disposed near the distal end. In one embodiment, the needle has a rigid, penetrating tip coupled to a flexible portion by an overlapping joint. The flexible portion enables the needle to bend to a penetrating angle relative to the distal end of the elongated tubular member and penetrate a body tissue without kinking.
摘要翻译：导管装置，其具有带近端和远端的细长管状构件，以及设置在远端附近的针。在一个实施例中，针具有通过重叠接头联接到柔性部分的刚性的穿透尖端。柔性部分使得针能够相对于细长管状构件的远端弯曲成穿透角度并穿透身体组织而不会扭结。

7. 发明申请

WO2004028233A2 METHODS AND DEVICES FOR ABLATION 审中-公开
标题翻译：用于排除的方法和装置
公开(公告)号：WO2004028233A2
公开(公告)日：2004-04-08
申请号：PCT/US2003/030163
申请日：2003-09-23
申请人： EPICOR MEDICAL, INCORPORATED , VASKA, Matthias , CROWE, John, E. , MILLER, Gary, Henry , PODMORE, Jonathan , CHAMPSAUR, Gerard , HOFFMAN, Drew , TANSEY, Casey
发明人： VASKA, Matthias , CROWE, John, E. , MILLER, Gary, Henry , PODMORE, Jonathan , CHAMPSAUR, Gerard , HOFFMAN, Drew , TANSEY, Casey
IPC分类号： A61B5/042 , A61B17/00 , A61B17/22 , A61B17/34 , A61B18/00 , A61B18/02 , A61B18/14 , A61B18/18 , A61B19/00 , A61M25/14 , A61N1/06 , A61N1/362 , A61N7/02
CPC分类号： A61B17/22012 , A61B5/0422 , A61B17/2202 , A61B17/2251 , A61B18/00 , A61B18/02 , A61B18/1402 , A61B18/148 , A61B18/1482 , A61B18/1492 , A61B34/20 , A61B2017/00243 , A61B2017/00247 , A61B2017/00252 , A61B2017/003 , A61B2017/22077 , A61B2017/2253 , A61B2017/3419 , A61B2018/00023 , A61B2018/0016 , A61B2018/00232 , A61B2018/00261 , A61B2018/00285 , A61B2018/00291 , A61B2018/00351 , A61B2018/00363 , A61B2018/00375 , A61B2018/00392 , A61B2018/00577 , A61B2018/00654 , A61B2018/00797 , A61B2018/00839 , A61B2018/142 , A61B2018/1467 , A61B2018/1472 , A61B2090/3614 , A61B2090/3782 , A61B2090/395 , A61B2218/002 , A61B2218/007 , A61M25/0041 , A61M25/0084 , A61M25/04 , A61M25/1002 , A61M25/1011 , A61M2025/0293 , A61M2025/1072 , A61N1/06 , A61N1/362 , A61N7/02
摘要： An ablating device has a cover which holds an interface material such as a gel. The cover contains the interface material during initial placement of the device. The ablating device may also have a removable tip or a membrane filled with fluid. In still another aspect, the ablating device may be submerged in liquid during operation.
摘要翻译：消融装置具有保持诸如凝胶的界面材料的盖。在设备的初始放置期间，盖子包含界面材料。烧蚀装置还可以具有可移除的尖端或填充有流体的膜。在另一方面，在操作期间，烧蚀装置可以浸没在液体中。

8. 发明申请

WO2003073358A2 DEVICES FOR APPLYING ENERGY TO TISSUE 审中-公开
标题翻译：用于施加能量组织的装置
公开(公告)号：WO2003073358A2
公开(公告)日：2003-09-04
申请号：PCT/US2003/004971
申请日：2003-02-21
申请人： BRONCUS TECHNOLOGIES, INC. , KEAST, Thomas , WILLINK, Christopher, Lee , ROSCHAK, Ed. , HAUGAARD, Dave , THOMPSON, David
发明人： KEAST, Thomas , WILLINK, Christopher, Lee , ROSCHAK, Ed. , HAUGAARD, Dave , THOMPSON, David
IPC分类号： G06K
CPC分类号： A61F2/90 , A61B5/489 , A61B8/06 , A61B8/12 , A61B8/445 , A61B17/064 , A61B17/0644 , A61B17/08 , A61B17/11 , A61B17/12104 , A61B17/22 , A61B17/320068 , A61B18/082 , A61B18/1477 , A61B18/1485 , A61B18/1492 , A61B18/1815 , A61B90/36 , A61B2017/00106 , A61B2017/00252 , A61B2017/00575 , A61B2017/1135 , A61B2017/1139 , A61B2017/22067 , A61B2017/22077 , A61B2018/00005 , A61B2018/00029 , A61B2018/00214 , A61B2018/00273 , A61B2018/00285 , A61B2018/00541 , A61B2018/00601 , A61B2018/00982 , A61B2018/1425 , A61B2018/1437 , A61B2018/1475 , A61B2090/08021 , A61B2090/3782 , A61B2090/395 , A61F2/02 , A61F2/07 , A61F2/20 , A61F2/2412 , A61F2/91 , A61F2/92 , A61F2002/043 , A61F2002/061 , A61F2002/8483 , A61N2007/0078
摘要： Disclosed herein are devices for altering gaseous flow within a lung to improve the expiration cycle of an individual, particularly individuals having Chronic Obstructive Pulmonary Disease (COPD). More particularly, devices are disclosed to produce collateral openings or channels through the airway wall so that expired air is able to pass directly out of the lung tissue to facilitate both the exchange of oxygen ultimately into the blood and/or to decompress hyper-inflated lungs.
摘要翻译：这里公开的是改变肺内的气流（118）以改善个体，特别是具有慢性阻塞性肺疾病（COPD）的个体的呼气循环的装置（200）。更具体地，公开了设备（200）以通过气道壁（106）产生旁路开口和通道（116），使得呼出空气能够直接从肺组织中通过，以便于最终将氧气交换到血液中和/或减压超膨胀的肺。

9. 发明申请

WO2003041597A1 PERCUTANEOUS CELLULITE REMOVAL SYSTEM 审中-公开
标题翻译： PERCUTANEOUSCELLULITE移除系统
公开(公告)号：WO2003041597A1
公开(公告)日：2003-05-22
申请号：PCT/US2002/036828
申请日：2002-11-14
申请人： EXPANDING CONCEPTS, L.L.C. , BRETT, Darrell, C.
发明人： BRETT, Darrell, C.
IPC分类号： A61B17/32
CPC分类号： A61B17/3478 , A61B17/32093 , A61B17/3403 , A61B17/3417 , A61B2017/22077 , A61B2017/320052 , A61M2202/08
摘要： A percutaneous cellulite removal needle (30, 30a, 30b, 30c) can be used to make the appearance of cellulite less obvious by cutting the fibrous bridges (28) that connect the skin (22) to muscle/facia (26) or fibrous septae in the subcutaneous fat in a minimally invasive manner. The percutaneous cellulite removal needle (30, 30a, 30b, 30c) preferably includes a body (32) having an internal chamber (33) that ends at a laterally disposed aperture (35). A cutting mechanism (31) is substantially positioned within the internal chamber (33) in a retracted position and at least partially protrudes through the laterally disposed aperture (35) in a cutting position. A situating mechanism (44, 44a, 44b, 44c) transitions the cutting mechanism (31) between the retracted position and the cutting position. A method in which the percutaneous cellulite removal needle (30, 30a, 30b, 30c) is inserted (104) through the skin (22) with the cutting mechanism (31) in the retracted position. The cutting mechanism (31) is then extruded (108) so that the cutting mechanism (31) is in the cutting position. Next the cutting mechanism (31) is actuated (110), for example by rotating, to cut at least one the fibrous bridge (28) or septae. These steps may be repeated to cut other fibrous bridges (28) or septae rechable by the cutting mechanism (31). The cutting mechanism (31) is then retracted (112) and the percutaneous cellulite removal needle (30, 30a, 30b, 30c) is removed.
摘要翻译：通过将连接皮肤（22）的纤维桥（28）切割成肌肉/面（26）或纤维间隔（26），可以使用经皮脂肪团去除针（30,30a，30b，30c）来使脂肪团的外观变得不明显以微创方式在皮下脂肪中。经皮脂肪去除针（30,30a，30b，30c）优选包括具有在侧向设置的孔（35）端部的内部腔室（33）的主体（32）。切割机构（31）基本上位于内部腔室（33）内处于缩回位置，并且在切割位置中至少部分地突出穿过横向设置的孔口（35）。位置机构（44,44a，44b，44c）在所述缩回位置和所述切割位置之间转动所述切割机构（31）。一种通过切割机构（31）在缩回位置通过皮肤（22）将经皮去脂针（30,30a，30b，30c）插入（104）的方法。然后将切割机构（31）挤压（108），使得切割机构（31）处于切割位置。接下来，切割机构（31）例如通过旋转来致动（110），以切割至少一个纤维桥（28）或隔片。可以重复这些步骤以切割由切割机构（31）可折叠的其它纤维桥（28）或隔片。然后将切割机构（31）缩回（112），并且去除经皮去脂针（30,30a，30b，30c）。

10. 发明申请

WO2002064045A1 DEVICES FOR CREATING COLLATERAL CHANNELS 审中-公开
标题翻译：创建通道的设备
公开(公告)号：WO2002064045A1
公开(公告)日：2002-08-22
申请号：PCT/US2002/004494
申请日：2002-02-14
申请人： BRONCUS TECHNOLOGIES, INC. , ROSCHAK, Ed , TANAKA, Don , HAUGAARD, Dave , KEAST, Thomas
发明人： ROSCHAK, Ed , TANAKA, Don , HAUGAARD, Dave , KEAST, Thomas
IPC分类号： A61B18/18
CPC分类号： A61B17/22 , A61B5/489 , A61B8/06 , A61B8/12 , A61B8/445 , A61B17/064 , A61B17/0644 , A61B17/08 , A61B17/11 , A61B18/1477 , A61B18/148 , A61B18/1485 , A61B18/1492 , A61B18/1815 , A61B90/36 , A61B2017/00106 , A61B2017/00252 , A61B2017/00575 , A61B2017/00809 , A61B2017/1135 , A61B2017/1139 , A61B2017/22067 , A61B2017/22077 , A61B2018/00005 , A61B2018/00029 , A61B2018/00214 , A61B2018/00273 , A61B2018/00285 , A61B2018/00541 , A61B2018/00898 , A61B2018/1425 , A61B2018/1437 , A61B2018/1475 , A61B2090/08021 , A61B2090/3782 , A61B2090/395 , A61F2/02 , A61F2/07 , A61F2/20 , A61F2/2412 , A61F2/2418 , A61F2/90 , A61F2/91 , A61F2/92 , A61F2002/043 , A61F2002/061 , A61F2002/072 , A61F2002/8483 , A61F2220/0008 , A61F2220/005 , A61F2220/0075 , A61F2230/005 , A61F2230/0054 , A61F2230/0058 , A61F2230/0067 , A61F2230/0076 , A61F2230/0078 , A61N2007/0078
摘要： The devices disclosed herein are directed to altering gaseous flow within a lung (118) to improve the expiration cycle of, for instance, an individual having Chronic Obstructive Pulmonary Disease. More particularly, these devices produce openings or channels (112) through the airway wall so that oxygen depleted/carbon dioxide rich air is able to pass directly out of the lung tissue to facilitate both the exchange of oxygen ultimately into the blood and/or to decompress hyper-inflated lungs.
摘要翻译：本文公开的装置旨在改变肺内的气流（118）以改善例如具有慢性阻塞性肺疾病的个体的呼气循环。更具体地，这些装置通过气道壁产生开口或通道（112），使得贫氧/富含二氧化碳的空气能够直接从肺组织中流出，以促进氧气最终进入血液和/或减压超膨胀肺。

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