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1. 发明申请

WO2004097416A1 MAGNETIC SUBSTANCE-BIOSUBSTANCE COMPLEX STRUCTURE, PEPTIDE FRAGMENT CAPABLE OF LINKING TO MAGNETIC SUBSTANCE AND GENE THEREFOR, AND PROCESS FOR STRUCTURE 审中-公开
标题翻译：磁性物质 - 生物传感器复合结构，能够连接到磁性物质及其基因的肽片段和结构过程
公开(公告)号：WO2004097416A1
公开(公告)日：2004-11-11
申请号：PCT/JP2004/006350
申请日：2004-04-30
申请人： CANON KABUSHIKI KAISHA , IMAMURA, Takeshi , YANO, Tetsuya , NOMOTO, Tsuyoshi , KOZAKI, Shinya , HONMA, Tsutomu , TSUCHITANI, Akiko
发明人： IMAMURA, Takeshi , YANO, Tetsuya , NOMOTO, Tsuyoshi , KOZAKI, Shinya , HONMA, Tsutomu , TSUCHITANI, Akiko
IPC分类号： G01N33/543
CPC分类号： C12N9/1025 , C07K2319/00 , C12N11/06 , C12N11/14 , C12N15/1013 , G01N33/54326 , G01N33/54353 , Y10S530/811
摘要： A magnetic substance-biosubstance complex structure comprises a magnetic substance-containing carrier and a biosubstance immobilized on the carrier, the biosubstance being immobilized through a spacer comprising an amino acid sequence on a surface of the carrier.
摘要翻译：磁性物质 - 生物物质复合物结构包括含磁性物质的载体和固定在载体上的生物体，生物质通过包含载体表面上的氨基酸序列的间隔物固定化。

2. 发明申请

WO2004097417A1 STRUCTURED CONSTRUCT AND PRODUCING METHOD THEREFOR 审中-公开
标题翻译：结构构造及其生产方法
公开(公告)号：WO2004097417A1
公开(公告)日：2004-11-11
申请号：PCT/JP2004/006420
申请日：2004-05-06
申请人： CANON KABUSHIKI KAISHA , IMAMURA, Takeshi , YANO, Tetsuya , HONMA, Tsutomu , KOZAKI, Shinya , NOMOTO, Tsuyoshi , TSUCHITANI, Akiko
发明人： IMAMURA, Takeshi , YANO, Tetsuya , HONMA, Tsutomu , KOZAKI, Shinya , NOMOTO, Tsuyoshi , TSUCHITANI, Akiko
IPC分类号： G01N33/543
CPC分类号： C12N9/93 , C07K2319/23 , C09D167/04 , C12N11/08 , C12P7/625 , G01N33/54326 , G01N33/54393 , G01N2333/21 , G01N2333/245
摘要： There is provided a construct in which at least a part of the magnetic material is coated with polyhydroxyalkanoate (PHA), and a method for producing a construct by immobilizing a PHA synthesizing enzyme on the surface of the magnetic material thereby biosynthesizing a PHAand coatingsuch PHA on the material.
摘要翻译：提供了其中至少一部分磁性材料涂覆有聚羟基链烷酸酯（PHA）的构造，以及通过将PHA合成酶固定在磁性材料的表面上从而生物合成PHA并将其涂覆在PHA上的方法材料。

3. 发明申请

WO2004097530A1 STRUCTURE AND METHOD FOR PRODUCING STRUCTURE, TONER CONTAINING STRUCTURE, IMAGE FORMING METHOD AND DEVICE USING TONER 审中-公开
标题翻译：用于生成结构的结构和方法，包含结构的图像，图像形成方法和使用调色剂的设备
公开(公告)号：WO2004097530A1
公开(公告)日：2004-11-11
申请号：PCT/JP2004/006349
申请日：2004-04-30
申请人： CANON KABUSHIKI KAISHA , YANO, Tetsuya , NOMOTO, Tsuyoshi , KOZAKI, Shinya , IMAMURA, Takeshi , HONMA, Tsutomu
发明人： YANO, Tetsuya , NOMOTO, Tsuyoshi , KOZAKI, Shinya , IMAMURA, Takeshi , HONMA, Tsutomu
IPC分类号： G03G9/093
CPC分类号： C12N9/93 , C07K2319/23 , C09D167/04 , C12N11/08 , C12P7/625 , G01N33/54326 , G01N33/54393 , G01N2333/21 , G01N2333/245
摘要： A structure, comprising a base material, coated with polymer which can be compatible with reduced load against environment and living organisms and various functionalities is provided. The base material is covered with polyhydroxyalkanoate (PHA). The invention also relates to a method for production of the structure comprising immobilizing the enzyme which synthesize PHA on the surface of the base material, biosynthesizing the PHA and coating the base material. The invention also provides toner containing such the structure and production thereof. Further, the invention relates to an image forming method comprising forming the image by providing such toner to the medium to be recorded.
摘要翻译：提供一种结构，其包括涂覆有聚合物的基材，该聚合物可以与降低的环境负荷和生物体相容并具有各种功能。基材用聚羟基链烷酸酯（PHA）覆盖。本发明还涉及一种用于生产该结构的方法，包括将在基材表面上合成PHA的酶固定化，生物合成PHA并涂覆该基材。本发明还提供含有这种结构和其制备的调色剂。此外，本发明涉及一种图像形成方法，包括通过向要记录的介质提供这种调色剂来形成图像。

4. 发明申请

WO2004096188A1 POLYHYDROXYALKANOATE-CONTAINING MAGNETIC STRUCTURE, AND MANUFACTURING METHOD AND USE THEREOF 审中-公开
标题翻译：含聚羟基烷酸钾的磁性结构及制造方法及其应用
公开(公告)号：WO2004096188A1
公开(公告)日：2004-11-11
申请号：PCT/JP2004/006296
申请日：2004-04-30
申请人： CANON KABUSHIKI KAISHA , YANO, Tetsuya , NOMOTO, Tsuyoshi , KOZAKI, Shinya , IMAMURA, Takeshi , HONMA, Tsutomu
发明人： YANO, Tetsuya , NOMOTO, Tsuyoshi , KOZAKI, Shinya , IMAMURA, Takeshi , HONMA, Tsutomu
IPC分类号： A61K9/50
CPC分类号： A61K9/5094 , A61K49/226 , Y10T428/12014
摘要： A structure containing polyhydroxyalkanoate and a magnetic substance includes an external phase part containing polyhydroxyalkanoate and an internal phase part contained in the external phase part, at least one of the external phase part and the internal phase part containing a magnetic substance. Accordingly, provided is a microcapsule, which can be suitably used for formation of an active ingredient of a sustained release pharmaceutical preparation or an ultrasonic contrast agent.
摘要翻译：包含聚羟基链烷酸酯和磁性物质的结构包括含有聚羟基链烷酸酯的外部部分和包含在外部相部分中的内相部分，外部相部分和内部相中的至少一个含有磁性物质。因此，提供了可适用于形成持续释放药物制剂或超声造影剂的活性成分的微胶囊。

5. 发明申请

WO2004044213A1 NOVEL POLYHYDROXY ALKANOATE COPOLYMER INCLUDING WITHIN MOLECULE UNIT HAVING VINYL GROUP OR CARBOXYL GROUP IN SIDE CHAIN, AND PRODUCING METHOD THEREFOR 审中-公开
标题翻译：新型聚羟基烷基酯共聚物，包括在具有乙烯基或羧基的分子单元中，并生产其中的方法
公开(公告)号：WO2004044213A1
公开(公告)日：2004-05-27
申请号：PCT/JP2003/013531
申请日：2003-10-23
申请人： CANON KABUSHIKI KAISHA , SUGAWA, Etsuko , KENMOKU, Takashi , YANO, Tetsuya , MIHARA, Chieko , KOZAKI, Shinya , HONMA, Tsutomu , FUKUI, Tatsuki , IMAMURA, Takeshi
发明人： KENMOKU, Takashi , YANO, Tetsuya , MIHARA, Chieko , KOZAKI, Shinya , HONMA, Tsutomu , FUKUI, Tatsuki , IMAMURA, Takeshi
IPC分类号： C12P7/62
CPC分类号： C08G63/06 , C08G63/6882 , C12P7/625
摘要： The invention provides a PHA copolymer including at least a 3-hydroxy-ω-carboxyalkanoic acid represented by a formula (19) or (32) and simultaneously at least a unit represented by a formula (2) or a formula (3) in a molecule, a precursor PHA copolymer having a corresponding vinyl group or a corresponding alkoxycarbonyl group, a biosynthesis method thereof by microorganisms, and a method of producing a desired PHA copolymer from the precursor PHA copolymer: (wherein k, m, n are integers; R 18 represents H, Na, K, R¿27? represents (A); R 1 represents a substituent on a cyclohexyl group and represents H, CN, NO 2 , a halogen atom, CH 3 , C 2 H 5 , C 3 H 7 , CF 3 , C 2 F 5 , or C 3 F 7 ; R includes a residue including a phenyl structure or a thienyl structure; these being independent for each unit).
摘要翻译：本发明提供一种PHA共聚物，其包含至少一种由式（19）或（32）表示的3-羟基-ω-羧基烷酸，同时至少由式（2）或式（3）表示的单元在分子，具有相应的乙烯基或相应的烷氧基羰基的前体PHA共聚物，微生物的生物合成方法以及由前体PHA共聚物制备所需PHA共聚物的方法（其中k，m，n为整数; R18 代表H，Na，K，R表示（A）; R1表示环己基上的取代基，代表H，CN，NO2，卤素原子，CH3，C2H5，C3H7，CF3，C2F5或C3F7; R 包括残基，包括苯基结构或噻吩基结构;它们对于每个单元是独立的）。

6. 发明申请

WO2005016971A1 ORGANIC MATERIAL-IMMOBILING STRUCTURE AND METHOD FOR PRODUCTION OF THE SAME, AND PEPTIDE AND DNA THEREFOR 审中-公开
标题翻译：有机材料 - 其制造方法及其生产方法，以及肽和其他DNA
公开(公告)号：WO2005016971A1
公开(公告)日：2005-02-24
申请号：PCT/JP2004/012153
申请日：2004-08-18
申请人： CANON KABUSHIKI KAISHA , SHIOTSUKA, Hidenori , IMAMURA, Takeshi , NOMOTO, Tsuyoshi , OGAWA, Miki
发明人： SHIOTSUKA, Hidenori , IMAMURA, Takeshi , NOMOTO, Tsuyoshi , OGAWA, Miki
IPC分类号： C07K17/14
CPC分类号： C07K17/14 , C07K7/08 , C07K17/08 , C12N11/14 , G01N33/54353 , G01N33/552
摘要： The invention provides an organic material-immobilizing structure employing new immobilization means, characterized in that at least a part of the surface of the substrate is comprised of one or more members containing silicon oxide, the organic material is bound to the surface of the substrate through a binding domain bound to the organic material and containing an amino acid sequence capable of binding to silicon oxide, selected from the group consisting of amino acid sequences of SEQ ID NOS: 1 and 2: Val-Ser-Pro-Met-Arg-Ser-Ala-Thr-Thr-His-Thr-Val; and Ile-Pro-Met-His-Val-His-His-Lys-His-Pro-His-Val, and derivatives thereof.
摘要翻译：本发明提供一种使用新的固定装置的有机材料固定结构，其特征在于，基底表面的至少一部分由含有氧化硅的一个或多个构件组成，有机材料通过与有机材料结合并含有能够结合氧化硅的氨基酸序列的结合结构域，其选自SEQ ID NO：1和2的氨基酸序列：Val-Ser-Pro-Met-Arg-Ser -Ala-THR-THR-的His-THR-缬氨酸; 和Ile-Pro-Met-His-Val-His-His-Lys-His-Pro-His-Val及其衍生物。

7. 发明申请

WO2004079241A1 LIQUID DELIVERY DEVICE 审中-公开
标题翻译：液体输送装置
公开(公告)号：WO2004079241A1
公开(公告)日：2004-09-16
申请号：PCT/JP2004/002499
申请日：2004-03-01
申请人： CANON KABUSHIKI KAISHA , YAMAZAKI, Takeo , TERASAKI, Atsunori , IMAMURA, Takeshi , EZAKI, Takahiro , YASUDA, Susumu , NAKAKUBO, Toru
发明人： YAMAZAKI, Takeo , TERASAKI, Atsunori , IMAMURA, Takeshi , EZAKI, Takahiro , YASUDA, Susumu , NAKAKUBO, Toru
IPC分类号： F16K17/30
CPC分类号： H01M8/04089 , B01L3/502738 , B01L2200/0605 , B01L2300/0816 , B01L2400/0418 , B01L2400/0487 , B01L2400/0638 , F16K99/0001 , F16K99/0009 , F16K99/0028 , F16K99/0057 , F16K2099/0074 , F16K2099/008 , F16K2099/0084 , G01N30/20 , G01N2030/205 , G01N2035/00247 , H01M8/04201 , H01M8/04216 , H01M8/065 , H01M2008/1095 , Y10T137/2191 , Y10T137/7869 , Y10T137/7895 , G01N30/10
摘要： A fluid delivery device is provided which comprises a microchannel device for cutting out a certain amount of a sample from a micorochannel by controlling a valve opening. The fluid delivery device has a valve (301) for controlling a flow of a fluid, comprising a flow channel (304) for the fluid, and a valve (301) in the flow channel, wherein the valve operates in accordance with a pressure difference between the upstream side (304) and downstream side (303) of the valve caused by the flow of the fluid through the flow channel, allowing the fluid to flow when the pressure difference is lower than a prescribed value P0, and intercepting the fluid not to flow when the pressure difference is P0 or more.
摘要翻译：提供了一种流体输送装置，其包括用于通过控制阀开口从微通道切出一定量的样品的微通道装置。流体输送装置具有用于控制流体流动的阀（301），其包括用于流体的流动通道（304）和流动通道中的阀（301），其中阀根据压差在通过流路的流体流动引起的阀的上游侧（304）和下游侧（303）之间，允许流体在压力差低于规定值P0时流动，并且使流体不截止流体当压力差为P0以上时流动。

8. 发明申请

WO2004010135A1 PROCESS FOR PRODUCING MASS TRANSFER DEVICE AND APPARATUS FOR PRODUCTION THEREOF 审中-公开
标题翻译：生产大容量转移装置的方法及其生产装置
公开(公告)号：WO2004010135A1
公开(公告)日：2004-01-29
申请号：PCT/JP2003/009017
申请日：2003-07-16
申请人： CANON KABUSHIKI KAISHA , YAMAZAKI, Takeo , MIHASHI, Naoto , IMAMURA, Takeshi , OMIZU, Satoko
发明人： YAMAZAKI, Takeo , MIHASHI, Naoto , IMAMURA, Takeshi , OMIZU, Satoko
IPC分类号： G01N30/56
CPC分类号： G01N30/466 , B01D15/206 , B01J19/0093 , B01J20/283 , B01J20/287 , B01J23/72 , B01J35/04 , B01J2219/00783 , B01J2219/00835 , B01J2219/00916 , B01L3/5027 , B01L3/502707 , B01L3/502753 , B01L2200/12 , G01N30/56 , G01N30/6043 , G01N30/6086 , G01N30/6095 , G01N2030/565
摘要： A process for producing a mass transfer device is provided which enables packing of a packing material uniformly in a flow channel, and transfers a specified substance by flowing a fluid containing the specified substance through a flow channel on a substrate. A mass transfer device produced by the process is also provided. The process for producing a mass transfer device comprises steps of preparing a substrate, forming a flow channel on the surface of the substrate, applying a liquid drop composed of a packing material and a liquid medium, and packing the packing material in the flow channel by removing the liquid medium.
摘要翻译：提供一种生产传质装置的方法，其能够将包装材料均匀地包封在流动通道中，并且通过使含有特定物质的流体通过基板上的流动通道流动来转移特定物质。还提供了通过该方法生产的传质装置。制造传质装置的方法包括以下步骤：制备基材，在基材的表面上形成流动通道，施加由包装材料和液体介质组成的液滴，并将包装材料包装在流动通道中去除液体介质。

9. 发明申请

WO2005095461A2 GOLD-BINDING PROTEIN AND USE THEREOF 审中-公开
标题翻译：金结合蛋白及其用途
公开(公告)号：WO2005095461A2
公开(公告)日：2005-10-13
申请号：PCT/JP2005/006815
申请日：2005-03-31
申请人： CANON KABUSHIKI KAISHA , SHIOTSUKA, Hidenori , IMAMURA, Takeshi , KUMAGAI, Izumi
发明人： SHIOTSUKA, Hidenori , IMAMURA, Takeshi , KUMAGAI, Izumi
IPC分类号： C07K16/44
CPC分类号： G01N33/532 , C07K16/44 , C07K2317/21 , C07K2317/56 , C07K2317/622 , C07K2317/92
摘要： A protein utilizing an anti-gold antibody and a gold-binding side which is a part of the anti-gold antibody is constructed. This protein is capable of specifically binding to gold. This protein or a complex protein containing such a protein can be used for the detection of a target substance.
摘要翻译：构建了使用抗金抗体和作为抗金抗体的一部分的金结合侧的蛋白质。该蛋白质能够特异性结合金。该蛋白质或含有这种蛋白质的复合蛋白质可用于检测目标物质。

10. 发明申请

WO2005071414A2 KIT FOR IMMOBILIZING ORGANIC SUBSTANCE, ORGANIC SUBSTANCE-IMMOBILIZED STRUCTURE, AND MANUFACTURING METHODS THEREFOR 审中-公开
标题翻译：用于固定有机物质，有机物质固定结构及其制造方法的工具包
公开(公告)号：WO2005071414A2
公开(公告)日：2005-08-04
申请号：PCT/JP2005/001316
申请日：2005-01-25
申请人： CANON KABUSHIKI KAISHA , BAN, Kazuhiro , SHIOTSUKA, Hidenori , IMAMURA, Takeshi
发明人： BAN, Kazuhiro , SHIOTSUKA, Hidenori , IMAMURA, Takeshi
IPC分类号： G01N33/543
CPC分类号： G01N33/54353 , G01N33/551
摘要： To provide an organic substance-immobilized structure employing a novel immobilizing technique and a manufacturing method thereof using the novel immobilizing technique, where, when an organic substance, particularly a biological substance is immobilized on the surface of a substrate, the organic substance, particularly the biological substance can be stably immobilized on the surface of the substrate through orientation of the organic substance, particularly the biological substance suitable for exerting physiological functions thereof. At least part of the substrate's surface is constructed of one or more substrates containing aluminum oxide. The immobilization of the organic substance to the surface of the substrate is carried out by binding at least part of the binding domain to the surface of the substrate through a binding domain containing a peptide having an affinity to aluminum oxide and composed of at least one or more amino acids, which is coupled with the organic substance.
摘要翻译：为了提供采用新型固定化技术的有机物质固定化结构及其制造方法，其中，当将有机物质，特别是生物物质固定在基材表面上时，有机物质，特别是生物物质可以通过有机物质，特别是适于发挥其生理功能的生物物质的取向，稳定地固定在基材的表面上。衬底表面的至少一部分由含有氧化铝的一个或多个衬底构成。有机物质固定到底物的表面是通过结合结构域与底物的表面结合而进行的，所述结合结构域含有与氧化铝具有亲和性的肽，并且由至少一个或多个更多的氨基酸，其与有机物质偶联。

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