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1. 发明申请

WO2010120694A1 ELECTRICAL CONTACT FOR OCCLUSIVE DEVICE DELIVERY SYSTEM 审中-公开
标题翻译：电气设备输送系统的电气接触
公开(公告)号：WO2010120694A1
公开(公告)日：2010-10-21
申请号：PCT/US2010/030753
申请日：2010-04-12
申请人： BOSTON SCIENTIFIC SCIMED, INC. , CHEN, Hancun , GUO, Lantao , DAO, Jimmy , VO, Justin , WILLIAMS, Michael , MURPHY, Richard
发明人： CHEN, Hancun , GUO, Lantao , DAO, Jimmy , VO, Justin , WILLIAMS, Michael , MURPHY, Richard
IPC分类号： A61B17/12
CPC分类号： A61B17/12022 , A61B17/12109 , A61B17/12145 , A61B17/1215 , A61B2017/12063
摘要： A delivery wire assembly for delivery of an occlusive device to a location in a patient's vasculature includes a delivery wire conduit having a proximal tubular portion coupled to a distal coil portion, the respective tubular and coil portions defining a conduit lumen. A core wire is disposed in the conduit lumen and having a distal end coupled to an occlusive device, wherein an elongate electrical contact body at least partially seated in the conduit lumen and coupled to a proximal end of the core wire, the electrical contact body and the proximal tubular portion forming a junction. A coil collar is disposed around the electrical contact body near the junction.
摘要翻译：用于将闭塞装置输送到患者脉管系统中的位置的输送线组件包括输送线导管，其具有联接到远端线圈部分的近端管状部分，相应的管状部分和线圈部分限定导管腔。芯线布置在导管管腔中并且具有联接到闭塞装置的远端，其中细长电接触体至少部分地位于导管管腔中并且联接到芯线的近端，电接触体和近端管状部分形成结。在接头附近的电接触体周围设置线圈套圈。

2. 发明申请

WO2010120653A1 DELIVERY WIRE FOR OCCLUSIVE DEVICE DELIVERY SYSTEM AND METHOD OF MANUFACTURE 审中-公开
标题翻译：用于交付设备传送系统的交付线及其制造方法
公开(公告)号：WO2010120653A1
公开(公告)日：2010-10-21
申请号：PCT/US2010/030620
申请日：2010-04-09
申请人： BOSTON SCIENTIFIC SCIMED, INC. , CHEN, Hancun , DAO, Jimmy , MURPHY, Richard
发明人： CHEN, Hancun , DAO, Jimmy , MURPHY, Richard
IPC分类号： A61B17/12
CPC分类号： A61B17/12022 , A61B17/12109 , A61B17/12145 , A61B17/1215 , A61B2017/12063 , Y10T29/49826
摘要： A delivery wire assembly for delivery of an occlusive device to a location in a patient's vasculature includes a delivery wire conduit having a proximal tubular portion coupled to a distal coil portion, the respective tubular and coil portions defining a conduit lumen, a plug at least partially seated in the conduit lumen and coupled to an interior surface of the coil portion so as to form a substantially fluid tight seal of the conduit lumen, and a core wire disposed in the conduit lumen, the core wire having a distal end extending through the plug and coupled to an occlusive device.
摘要翻译：用于将闭塞装置输送到患者脉管系统中的位置的输送线组件包括输送线导管，其具有联接到远端线圈部分的近端管状部分，相应的管状部分和线圈部分限定导管管腔，塞子至少部分地位于导管管腔中并联接到线圈部分的内表面，以便形成导管管腔的基本上流体密封的密封，以及设置在导管管腔中的芯线，芯线具有延伸穿过插塞的远端并耦合到闭塞装置。

3. 发明申请

WO2010117883A1 DELIVERY WIRE FOR OCCLUSIVE DEVICE DELIVERY SYSTEM 审中-公开
标题翻译：用于交付设备传送系统的交付线
公开(公告)号：WO2010117883A1
公开(公告)日：2010-10-14
申请号：PCT/US2010/029700
申请日：2010-04-01
申请人： BOSTON SCIENTIFIC SCIMED, INC. , CHEN, Hancun , DAO, Jimmy , MURPHY, Richard
发明人： CHEN, Hancun , DAO, Jimmy , MURPHY, Richard
IPC分类号： A61B17/12
CPC分类号： A61B17/12113 , A61B17/12022 , A61B17/12109 , A61B17/1214 , A61B17/12145 , A61B17/1215 , A61B90/39 , A61B2017/12063 , A61B2017/12068 , A61M2025/09133 , A61M2025/0915
摘要： A delivery wire assembly for delivery of an occlusive device to a location in a patient's vasculature includes a delivery wire conduit having a proximal tubular portion connected to a distal coil portion, and a conduit lumen extending through the proximal tubular portion and the distal coil portion. The delivery wire assembly also includes a core wire disposed in the conduit lumen and having a distal end coupled to an occlusive device. The distal coil portion of the delivery wire assembly includes a plurality of zones and the plurality of zones decrease in stiffness distally along the length of the distal coil portion of the delivery wire assembly.
摘要翻译：用于将闭塞装置输送到患者脉管系统中的位置的输送线组件包括输送线导管，其具有连接到远侧线圈部分的近端管状部分和延伸穿过近端管状部分和远端线圈部分的管腔。输送线组件还包括设置在导管管腔中并且具有联接到闭塞装置的远端的芯线。输送线组件的远端线圈部分包括多个区域，并且多个区域沿着输送线组件的远端线圈部分的长度向远侧减小。

4. 发明申请

WO2011060128A2 DELIVERY WIRE ASSEMBLY FOR OCCLUSIVE DEVICE DELIVERY SYSTEM 审中-公开
标题翻译：交付设备传送系统的交付线组件
公开(公告)号：WO2011060128A2
公开(公告)日：2011-05-19
申请号：PCT/US2010/056330
申请日：2010-11-11
申请人： BOSTON SCIENTIFIC SCIMED, INC. , CHEN, Hancun , MURPHY, Richard , DAO, Jimmy
发明人： CHEN, Hancun , MURPHY, Richard , DAO, Jimmy
IPC分类号： A61B17/12 , A61B17/00
CPC分类号： A61B17/12022 , A61B17/12109 , A61B17/12145 , A61B17/1215 , A61B17/12154 , A61B2017/0088 , A61B2017/12063 , A61B2018/00083
摘要： A core wire of a delivery wire assembly for delivery of an occlusive device to a location in a patient's vasculature, includes a wire having a polyimide coating, with a polymer jacket disposed around the polyimide coating, and a hypotube disposed around the polymer jacket. The delivery wire assembly further comprises a delivery wire conduit including a coil disposed around the wire, wherein a proximal end of the coil is connected to a distal end of the hypotube. The polyimide coating may be enhanced with a nano-particle or micro-fiber ceramic, such as yttria-stabilized zirconia.
摘要翻译：用于将闭塞装置输送到患者脉管系统中的位置的输送线组件的芯线包括具有聚酰亚胺涂层的线，聚酰亚胺涂层周围设置聚合物护套，以及设置在聚合物护套周围的海波管。输送线组件还包括输送线导管，其包括设置在线周围的线圈，其中线圈的近端连接到海波管的远端。聚酰亚胺涂层可以用纳米颗粒或微纤维陶瓷如氧化钇稳定的氧化锆来增强。

5. 发明申请

WO2011126946A1 VASO-OCCLUSIVE DEVICES 审中-公开
标题翻译： VASO-OCCLUSIVE设备
公开(公告)号：WO2011126946A1
公开(公告)日：2011-10-13
申请号：PCT/US2011/030972
申请日：2011-04-01
申请人： BOSTON SCIENTIFIC SCIMED, INC. , CHEN, Hancun , MURPHY, Richard
发明人： CHEN, Hancun , MURPHY, Richard
IPC分类号： A61B17/12 , A61B17/00
CPC分类号： A61B17/12022 , A61B17/12113 , A61B17/1214 , A61B17/12145 , A61B17/12154 , A61B2017/00831 , A61B2017/12054 , A61B2017/12063 , A61B2090/3966
摘要： Vaso-occlusive device includes a coil having a proximal and a distal end; the coil comprises a helically wounded elongated member having a core and an outer layer, the outer layer made from a metal or alloy that has a different stiffness than a core's stiffness. Vaso-occlusive device includes a first coil and a second coil coupled to each other such that at least one loop from the first coil is between two adjacent loops from the second coil; the first coil is made from a first material, and the second coil is made from a second material stiffer than the first material. Vaso-occlusive device includes an outer coil having a plurality of loops that define a lumen therethrough, and an inner coil located within the lumen of the outer coil; each of the outer and the inner coils is made from a metal or an alloy.
摘要翻译：血管闭塞装置包括具有近端和远端的线圈; 线圈包括具有芯和外层的螺旋形受伤的细长构件，外层由具有与芯刚度不同的刚度的金属或合金制成。血管闭塞装置包括彼此联接的第一线圈和第二线圈，使得来自第一线圈的至少一个回路位于来自第二线圈的两个相邻的回路之间; 第一线圈由第一材料制成，并且第二线圈由比第一材料更硬的第二材料制成。血管闭塞装置包括具有限定通过其中的腔的多个环的外部线圈和位于外部线圈的内腔内的内部线圈; 外线圈和内线圈均由金属或合金制成。

6. 发明申请

WO2011062844A1 DELIVERY WIRE ASSEMBLY FOR OCCLUSIVE DEVICE DELIVERY SYSTEM 审中-公开
标题翻译：交付设备传送系统的交付线组件
公开(公告)号：WO2011062844A1
公开(公告)日：2011-05-26
申请号：PCT/US2010/056483
申请日：2010-11-12
申请人： BOSTON SCIENTIFIC SCIMED, INC. , CHEN, Hancun , MURPHY, Richard , CASTELLI, Shana
发明人： CHEN, Hancun , MURPHY, Richard , CASTELLI, Shana
IPC分类号： A61B17/12 , A61B17/00 , A61F2/82
CPC分类号： A61B17/12022 , A61B17/12031 , A61B17/12109 , A61B17/12145 , A61B17/1215 , A61B2017/00292 , A61B2017/00734 , A61B2017/12063
摘要： A delivery wire assembly for delivery of an occlusive device to a location in a patient's vasculature, the assembly having a distal end portion comprising a proximal rigid segment, a distal rigid segment, and a flexible segment disposed between the proximal and distal rigid segments. The assembly also has a delivery wire conduit having a proximal tubular portion coupled to a distal coil portion, the respective tubular and coil portions defining a conduit lumen. A plug is seated in the conduit lumen and secured to an interior surface of the delivery wire conduit. A core wire is disposed in the conduit lumen and having a distal end extending through the plug, so that the plug secures the core wire to the delivery wire conduit. The plug may form a substantially fluid tight seal of the conduit lumen.
摘要翻译：用于将闭塞装置输送到患者脉管系统中的位置的输送线组件，所述组件具有包括近端刚性段，远侧刚性段和设置在近端和远端刚性段之间的柔性段的远端部分。组件还具有输送线导管，其具有联接到远端线圈部分的近端管状部分，相应的管状部分和线圈部分限定导管腔。塞子位于导管管腔中并固定到输送线管道的内表面。芯线设置在导管管腔中并且具有延伸穿过插塞的远端，使得插头将芯线固定到输送线导管。塞子可以形成导管管腔的基本上流体密封的密封。

7. 发明申请

WO2012109388A1 VASO-OCCLUSIVE DEVICE 审中-公开
标题翻译： VASO-OCCLUSIVE设备
公开(公告)号：WO2012109388A1
公开(公告)日：2012-08-16
申请号：PCT/US2012/024377
申请日：2012-02-08
申请人： STRYKER CORPORATION , STRYKER NV OPERATIONS LIMITED , CHEN, Hancun , MURPHY, Richard , DAO, Jimmy
发明人： CHEN, Hancun , MURPHY, Richard , DAO, Jimmy
IPC分类号： A61B17/12
CPC分类号： A61B17/12022 , A61B17/12109 , A61B17/12113 , A61B17/1214 , A61B17/12145 , A61B17/1215
摘要： A vaso-occlusive device includes a first wire having a first cross-sectional geometry and a second wire having a second cross-sectional geometry, where the first cross-sectional geometry is different from the second cross-sectional geometry. The first wire may be wound to form a first coil, where the second wire is wound to form a second coil defining a lumen therein, and where the first coil is disposed at least partially in the lumen. The first wire and the second wire may be co-wound to form a single coil.
摘要翻译：血管闭塞装置包括具有第一横截面几何形状的第一线和具有第二横截面几何形状的第二线，其中第一横截面几何形状不同于第二横截面几何形状。第一线可以被缠绕以形成第一线圈，其中第二线被缠绕以形成在其中限定内腔的第二线圈，并且其中第一线圈至少部分地设置在内腔中。第一线和第二线可以共同缠绕以形成单个线圈。

8. 发明申请

WO2009143160A1 MEDICAL DEVICE INCLUDING A BRAID FOR CROSSING AN OCCLUSION IN A VESSEL 审中-公开
标题翻译：医疗装置，包括用于横穿血管内的血管的BRAID
公开(公告)号：WO2009143160A1
公开(公告)日：2009-11-26
申请号：PCT/US2009/044529
申请日：2009-05-19
申请人： BOSTON SCIENTIFIC SCIMED, INC. , CHEN, Hancun , ZHOU, Pu
发明人： CHEN, Hancun , ZHOU, Pu
IPC分类号： A61M25/09
CPC分类号： A61M25/09033 , A61M2025/09075 , A61M2025/09108 , A61M2025/09133 , A61M2025/09175
摘要： The application provides design, material, manufacturing method, and use alternatives for medical devices. An example medical guidewire (10) includes an elongate core member (20) including a proximal region (14) and a distal region (12), a braid member (18) disposed about at least a portion of the distal region of the elongate core member, a polymer member (24) disposed between at least a portion of the elongate core member and the braid member, and a polymer sleeve member (16) disposed about at least a portion of the braid member. The proximal region of the core member is free of the braid member.
摘要翻译：该应用程序提供医疗设备的设计，材料，制造方法和使用替代品。示例性医疗导线（10）包括细长的芯构件（20），其包括近侧区域（14）和远侧区域（12），编织构件（18）围绕细长芯的远侧区域的至少一部分构件，设置在细长芯构件和编织构件的至少一部分之间的聚合物构件（24）和围绕编织构件的至少一部分设置的聚合物套筒构件（16）。芯构件的近侧区域没有编织构件。

9. 发明申请

WO2008024593A2 MEDICAL DEVICE COATING CONFIGURATION AND METHOD FOR IMPROVED LUBRICITY AND DURABILITY 审中-公开
标题翻译：医疗设备涂层配置和改善润滑性和耐久性的方法
公开(公告)号：WO2008024593A2
公开(公告)日：2008-02-28
申请号：PCT/US2007/074563
申请日：2007-07-27
申请人： BOSTON SCIENTIFIC SCIMED, INC. , CHEN, Hancun
发明人： CHEN, Hancun
IPC分类号： A61F2/82
CPC分类号： A61M25/09
摘要： Medical devices and methods for making and using the same. An example medical device includes a slotted tubular member and a coating disposed over the tubular member. The coating may define one or more coating gaps therein.
摘要翻译：
医疗设备及其制造和使用方法。示例医疗装置包括开槽管状构件和布置在管状构件上的涂层。涂层可以在其中限定一个或多个涂层间隙。

10. 发明申请

WO2011053625A1 DELIVERY WIRE ASSEMBLY FOR OCCLUSIVE DEVICE DELIVERY SYSTEM 审中-公开
标题翻译：交付设备传送系统的交付线组件
公开(公告)号：WO2011053625A1
公开(公告)日：2011-05-05
申请号：PCT/US2010/054228
申请日：2010-10-27
申请人： BOSTON SCIENTIFIC SCIMED, INC. , CHEN, Hancun
发明人： CHEN, Hancun
IPC分类号： A61B17/12
CPC分类号： A61B17/12022 , A61B17/12109 , A61B17/12145 , A61B17/1215 , A61B17/12154 , A61B2017/12063
摘要： A delivery wire assembly for delivering an occlusive device to a location in a patient's vasculature, includes delivery wire conduit defining a conduit lumen, a core wire disposed in the conduit lumen, the core wire having a distal detachment zone, and an enhancing coil disposed around the distal detachment zone, the enhancing coil configured to transfer a distally directed force from the delivery wire assembly to objects located distal of the delivery wire assembly without damaging the distal detachment zone. In one embodiment, the enhancing coil includes a proximal section having a first diameter, a distal section having a diameter larger than the diameter of the proximal section, and a transition section connecting the respective proximal and distal sections, wherein the transition section flares radially in a distal direction.
摘要翻译：用于将闭塞装置输送到患者脉管系统中的位置的输送线组件包括限定导管腔的输送线导管，设置在导管管腔中的芯线，具有远端脱离区的芯线和围绕所述远端脱离区域，所述增强线圈被配置为将远端定向的力从所述输送线组件传递到位于所述输送线组件远侧的物体，而不损坏所述远端脱离区。在一个实施例中，增强线圈包括具有第一直径的近端部分，具有大于近端部分的直径的直径的远端部分和连接相应的近端部分和远端部分的过渡部分，其中过渡部分径向地以远端方向。

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