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1. 发明申请

WO2018005043A1 ELECTROLYTIC DETACHMENT FOR IMPLANTABLE DEVICES 审中-公开
标题翻译：可植入设备的电解分离
公开(公告)号：WO2018005043A1
公开(公告)日：2018-01-04
申请号：PCT/US2017/036699
申请日：2017-06-09
申请人： COVIDIEN LP
发明人： RHEE, Richard , KADAM, Madhur , DIVINO, Vincent
IPC分类号： A61B17/12
CPC分类号： A61B17/1214 , A61B17/12099 , A61B17/12113 , A61B17/12172 , A61B2017/00526 , A61B2017/12063
摘要： Delivery and detachment of an implant (20) can be enhanced by a retraction mechanism to secure portions of a delivery wire (44) within an interior space of the implant (20). A delivery system (10) can include an implant (20) having a proximal end portion (50). A delivery wire (44) can include (i) a detachment zone (30) proximal to the proximal end portion (50) and (ii) a distal region (80) distal to the proximal end portion. An expansion member (60) can be located between the proximal end portion (50) and the distal region (80) of the delivery wire. The expansion member (60) can be biased to move the distal region (80) of the delivery wire (44) distally away from the proximal end portion (50) when severed at the detachment zone (30).
摘要翻译：植入物（20）的递送和分离可通过回缩机构来增强，以将递送线（44）的部分固定在植入物（20）的内部空间内。递送系统（10）可以包括具有近端部分（50）的植入物（20）。输送线（44）可以包括（i）靠近近端部分（50）的分离区（30）和（ii）远端区域（80）。扩张构件（60）可以位于输送线的近端部分（50）和远端区域（80）之间。当在分离区（30）处切断时，扩张构件（60）可被偏压以使输送线（44）的远侧区域（80）向远侧远离近侧端部分（50）移动。

2. 发明申请

WO2014111911A1 MONOFILAMENT IMPLANTS AND SYSTEMS FOR DELIVERY THEREOF 审中-公开
标题翻译：用于交付的单体植入物和系统
公开(公告)号：WO2014111911A1
公开(公告)日：2014-07-24
申请号：PCT/IL2013/050981
申请日：2013-11-27
申请人： JAVELIN MEDICAL LTD.
发明人： SHINAR, Guy , YODFAT, Ofer
IPC分类号： A61F2/82 , A61F2/88 , A61F2/844
CPC分类号： A61F2/01 , A61B17/12031 , A61B17/12036 , A61B17/12109 , A61B17/12145 , A61B17/3468 , A61B90/39 , A61B2017/00004 , A61B2017/00398 , A61B2017/1205 , A61B2017/12063 , A61F2/88 , A61F2002/011 , A61F2002/016 , A61F2220/0008 , A61F2220/0016 , A61F2230/0071 , A61F2230/0091 , A61F2250/0098
摘要： Systems, devices and methods are presented for embolic protection. In some embodiments, a device for implantation in a patient's vessel containing a fluid flow is provided which comprises proximal and distal ends, an undeployed, substantially linear state, and a deployed, spring-like (helical) state comprising windings. When the device is deployed, the line segment connecting the proximal and distal ends is approximately perpendicular to the majority of the windings and to the fluid flow. In some embodiments, a delivery device for the monofilament device is provided. The delivery device comprises a needle having a lumen, a sharp distal end, and a pusher slidable within the needle. A method for deploying the monofilament device using the delivery device is provided.
摘要翻译：系统，设备和方法用于栓塞保护。在一些实施例中，提供了用于植入包含流体流动的患者容器中的装置，其包括近端和远端，未部署的，基本上线性的状态，以及包括绕组的展开的弹簧状（螺旋状）状态。当设备被部署时，连接近端和远端的线段大致垂直于大部分绕组和流体流。在一些实施例中，提供了用于单丝装置的输送装置。递送装置包括具有内腔，尖锐远端和在针内可滑动的推动器的针。提供了使用输送装置来展开单丝装置的方法。

3. 发明申请

WO2013179137A3 SYSTEMS, METHODS AND DEVICES FOR EMBOLIC PROTECTION 审中-公开
标题翻译：用于嵌入式保护的系统，方法和装置
公开(公告)号：WO2013179137A3
公开(公告)日：2014-03-20
申请号：PCT/IB2013001336
申请日：2013-05-30
申请人： JAVELIN MEDICAL LTD
发明人： SHINAR GUY , YODFAT OFER
IPC分类号： A61F2/01
CPC分类号： A61F2/01 , A61B17/0401 , A61B17/0467 , A61B17/0487 , A61B17/12031 , A61B17/12036 , A61B17/12109 , A61B17/12145 , A61B17/122 , A61B90/39 , A61B2017/00004 , A61B2017/0409 , A61B2017/0417 , A61B2017/045 , A61B2017/0464 , A61B2017/0496 , A61B2017/12063 , A61F2002/011 , A61F2002/016 , A61F2230/0071 , A61F2230/0091 , A61F2250/0098
摘要： Embodiments of the present disclosure are directed to systems, methods and devices for providing embolic protection in a patient. In some embodiments, the device is configured for implantation in a body vessel including fluid flow. The device may assume, or be constrained to assume, an undeployed state and a deployed state. In the undeployed state, the device or a portion thereof has a substantially linear shape configured to reside in the lumen of a thin needle having a diameter of less than about 0.5 mm (for example). In the deployed state, the device has a primary axis. When the device is implanted the primary axis is approximately perpendicular to the fluid flow.
摘要翻译：本公开的实施例涉及用于在患者体内提供栓塞保护的系统，方法和装置。在一些实施例中，该装置构造成用于植入包括流体流动的身体容器中。该设备可以假设或被约束以呈现未部署状态和部署状态。在非部署状态下，该装置或其一部分具有构造成位于直径小于约0.5mm（例如）的细针的内腔中的基本线性形状。在部署状态下，设备具有主轴。当装置被植入时，主轴线近似垂直于流体流动。

4. 发明申请

WO2012118957A3 ENDOVASCULAR CLOSURE SYSTEM 审中-公开
标题翻译： ENDOVASCULAR封闭系统
公开(公告)号：WO2012118957A3
公开(公告)日：2012-11-01
申请号：PCT/US2012027259
申请日：2012-03-01
申请人： ESKRIDGE JOE MICHAEL
发明人： ESKRIDGE JOE MICHAEL
IPC分类号： A61B17/122 , A61F2/04 , A61F2/06 , A61L27/02
CPC分类号： A61B18/08 , A61B17/12022 , A61B17/12113 , A61B17/12172 , A61B2017/00327 , A61B2017/00336 , A61B2017/00477 , A61B2017/00526 , A61B2017/00849 , A61B2017/00853 , A61B2017/00867 , A61B2017/00942 , A61B2017/12063 , A61B2090/3966 , A61L31/022 , A61L31/048 , A61L31/10 , A61L2400/16 , Y10T156/10 , C08L27/18 , C08L83/00
摘要： An aneurysm closure device (10) having a pair of retention clips (16A, 18A and 16B, 18B) joined together. Each of the clips (16A, 18A and 16B, 18B) has an aneurysm (16A and 16B) anchor joined to a root-vessel anchor (18A and 18B), and is made of material having a resilient installed state, in which the aneurysm anchor and the root -vessel anchor are urged together, thereby squeezing and being retained by interposed tissue. Also, an aneurysm seal bridges the clips, sealing the aneurysm when the device is implanted, thereby causing the aneurysm to atrophy.
摘要翻译：动脉瘤闭合装置（10）具有结合在一起的一对保持夹（16A，18A和16B，18B）。每个夹子（16A，18A和16B，18B）具有连接到根管锚（18A和18B）的动脉瘤（16A和16B）锚，并且由具有弹性安装状态的材料制成，其中动脉瘤锚和锚根锚被一起推压，从而挤压并由插入的组织保持。此外，动脉瘤密封件桥接夹子，当装置植入时密封动脉瘤，从而导致动脉瘤萎缩。

5. 发明申请

WO2012109367A1 VASO-OCCLUSIVE DEVICE DELIVERY SYSTEM 审中-公开
标题翻译： VASO-OCCLUSIVE设备交付系统
公开(公告)号：WO2012109367A1
公开(公告)日：2012-08-16
申请号：PCT/US2012/024349
申请日：2012-02-08
申请人： STRYKER CORPORATION , STRYKER NV OPERATIONS LIMITED , CHEN, Hancun , MURPHY, Richard
发明人： CHEN, Hancun , MURPHY, Richard
IPC分类号： A61B17/12
CPC分类号： A61B17/12022 , A61B17/1214 , A61B17/12145 , A61B17/1215 , A61B17/12154 , A61B2017/12063
摘要： A vaso-occlusive device delivery system includes a delivery wire assembly having a core wire disposed in a delivery wire lumen, and a vaso-occlusive device having a tapered proximal end and defining a vaso-occlusive device lumen, wherein a tether is disposed in the lumen and secured to the core wire. A link may be attached to each of the core wire, the proximal end of the vaso-occlusive device, and the tether. Alternatively, the system may include a transition member attached to the vaso-occlusive device and secured to the core wire.
摘要翻译：血管闭塞装置递送系统包括具有布置在输送丝腔内的芯线的输送线组件和具有锥形近端并限定血管闭塞装置内腔的血管闭塞装置，其中系绳设置在内腔并固定在芯线上。连接件可以连接到芯线，血管闭塞装置的近端和系绳中的每一个。或者，系统可以包括附接到血管闭塞装置并固定到芯线的过渡构件。

6. 发明申请

WO2012099910A2 BALLSTENT DEVICE AND METHODS OF USE 审中-公开
标题翻译： BALLSTENT装置及其使用方法
公开(公告)号：WO2012099910A2
公开(公告)日：2012-07-26
申请号：PCT/US2012021621
申请日：2012-01-17
申请人： NOVITA THERAPEUTICS LLC , FRANANO F NICHOLAS
发明人： FRANANO F NICHOLAS
IPC分类号： A61M25/10
CPC分类号： A61F2/958 , A61B17/12031 , A61B17/12109 , A61B17/12131 , A61B17/12136 , A61B2017/00526 , A61B2017/00893 , A61B2017/12054 , A61B2017/12059 , A61B2017/12063 , A61B2017/12068 , A61B2090/037 , A61F2/06 , A61M25/1029 , Y10T29/49826
摘要： What is disclosed are medical devices comprising a rounded, thin-walled, expandable metal structure ("ballstent") and a flexible, elongated delivery device ("delivery catheter") and systems and methods of use for treating saccular vascular aneurysms with the medical devices. Ballstents comprised of gold, platinum, or silver that can be compressed, positioned in the lumen of an aneurysm, and expanded to conform to the shape of the aneurysm are disclosed. The external surface of ballstents can be configured to promote local thrombosis and to promote the growth of tissue into and around the wall of the ballstent in order to seal the aneurysm and fix the ballstent in place in the aneurysm. The wall of the ballstent can also be configured to release drugs or pharmacologically active molecules, such as those that promote thrombosis, cell proliferation, extracellular matrix deposition, and tissue growth.
摘要翻译：公开的是包括圆形，薄壁，可扩展金属结构（“球状液体”）和柔性细长输送装置（“输送导管”）的医疗装置以及用于用医疗装置治疗囊状血管动脉瘤的系统和方法。公开了可以压缩的位于动脉瘤内腔中的金，铂或银的球状体，并且膨胀以符合动脉瘤的形状。球形体的外表面可以被配置为促进局部血栓形成并促进组织在球状体壁中和周围的生长，以便密封动脉瘤并将球状体固定在动脉瘤中的适当位置。球状体的壁还可以被配置为释放药物或药理活性分子，例如促进血栓形成，细胞增殖，细胞外基质沉积和组织生长的分子。

7. 发明申请

WO2011126946A9 VASO-OCCLUSIVE DEVICES 审中-公开
标题翻译： VASO-OCCLUSIVE设备
公开(公告)号：WO2011126946A9
公开(公告)日：2012-07-19
申请号：PCT/US2011030972
申请日：2011-04-01
申请人： BOSTON SCIENT SCIMED INC , CHEN HANCUN , MURPHY RICHARD
发明人： CHEN HANCUN , MURPHY RICHARD
IPC分类号： A61B17/12 , A61B17/00
CPC分类号： A61B17/12022 , A61B17/12113 , A61B17/1214 , A61B17/12145 , A61B17/12154 , A61B2017/00831 , A61B2017/12054 , A61B2017/12063 , A61B2090/3966
摘要： Vaso-occlusive device includes a coil having a proximal and a distal end; the coil comprises a helically wounded elongated member having a core and an outer layer, the outer layer made from a metal or alloy that has a different stiffness than a core's stiffness. Vaso-occlusive device includes a first coil and a second coil coupled to each other such that at least one loop from the first coil is between two adjacent loops from the second coil; the first coil is made from a first material, and the second coil is made from a second material stiffer than the first material. Vaso-occlusive device includes an outer coil having a plurality of loops that define a lumen therethrough, and an inner coil located within the lumen of the outer coil; each of the outer and the inner coils is made from a metal or an alloy.
摘要翻译：血管闭塞装置包括具有近端和远端的线圈; 线圈包括具有芯和外层的螺旋形受伤的细长构件，外层由具有与芯刚度不同的刚度的金属或合金制成。血管闭塞装置包括彼此联接的第一线圈和第二线圈，使得来自第一线圈的至少一个回路位于来自第二线圈的两个相邻的回路之间; 第一线圈由第一材料制成，并且第二线圈由比第一材料更硬的第二材料制成。血管闭塞装置包括具有限定通过其中的腔的多个环的外部线圈和位于外部线圈的内腔内的内部线圈; 外线圈和内线圈均由金属或合金制成。

8. 发明申请

WO2011147567A1 VORRICHTUNG ZUM EINBRINGEN EINES IMPLANTATS 审中-公开
标题翻译：装置用于引入植入物
公开(公告)号：WO2011147567A1
公开(公告)日：2011-12-01
申请号：PCT/EP2011/002592
申请日：2011-05-25
申请人： PHENOX GMBH , APORTA, Carsten , ASCHERFELD, Jörg , HANNES, Ralf , MONSTADT, Hermann
发明人： APORTA, Carsten , ASCHERFELD, Jörg , HANNES, Ralf , MONSTADT, Hermann
IPC分类号： A61F2/84 , A61B17/12
CPC分类号： A61F2/95 , A61B17/12022 , A61B17/12113 , A61B17/1214 , A61B2017/12063 , A61B2017/12072 , A61B2017/12086 , A61F2002/9505
摘要： Die Erfindung betrifft eine Vorrichtung umfassend ein endovaskuläres Implantat (1), das zur Einbringung in Blutgefäße oder Körperhohlräume des menschlichen oder tierischen Körpers vorgesehen ist, und eine Einführhilfe (2), wobei das Implantat (1) und die Einführhilfe (2) über ein Ablöseelement (3) miteinander verbunden sind, welches elektrolytisch korrodierbar ausgebildet ist, so dass nach Einbringen des Implantats (1) in den Körper durch Anlegen einer Spannung eine zumindest teilweise Auflösung des Ablöseelementes (3) und eine Ablösung des Implantats (1) von der Einführhilfe (2) erfolgt, wobei das Ablöseelement (3) aus einer Cobalt-Chrom-Legierung, enthaltend mindestens 20 Gew.-% Cobalt und 10 bis 40 Gew.-% Chrom, gefertigt ist.
摘要翻译：本发明涉及一种包括血管内移植物（1），其被提供用于插入到血管或人体或动物体的体腔的装置，和插入辅助件（2），其中，所述植入物（1）和插入辅助（2）经由一个分离元件（3）彼此连接，这是电解形成腐蚀的，从而使植入物（1）到体内的插入之后（通过施加电压的，释放元件的至少部分溶解（3）和植入物的分离（1）插入器的 2），其中所述释放元件（3）由含至少20重量％的钴 - 铬合金的是钴，铬10〜40重量％，制。

9. 发明申请

WO2010011694A1 VASCULAR REMODELING DEVICE 审中-公开
标题翻译：血管重建装置
公开(公告)号：WO2010011694A1
公开(公告)日：2010-01-28
申请号：PCT/US2009/051316
申请日：2009-07-21
申请人： MICRO THERAPEUTICS, INC.
发明人： LEVY, Elad , SLEE, Earl , SHRIVASTAVA, Sanjay , SCHUMAN, Victoria , HUYNH, Andy , LU, Wenfeng
IPC分类号： A61B17/12 , A61F2/82 , A61F2/06
CPC分类号： A61F2/86 , A61B17/12022 , A61B17/12113 , A61B17/12118 , A61B17/1214 , A61B17/12172 , A61B2017/12054 , A61B2017/12063 , A61F2/954 , A61F2002/065 , A61F2002/823 , A61F2230/005 , A61F2230/0071
摘要： A generally spherical vascular remodeling device (50, 80, 110, 130) is permanently positionable at a junction of afferent and efferent vessels of a bifurcation (60) having an aneurysm (20). After positioning the device (50, 80, 110, 130) at the junction to substantially conform the device (50, 80, 110, 130) to the shape of the junction, the device (50, 80, 110, 130) acts as a scaffolding to inhibit herniation of objects out of the aneurysm (20) and the device (50, 80, 110, 130) permits perfusion to the efferent vessels. Positioning the device (50, 80, 110, 130) may include deployment and mechanical or electrolytic release from a catheter (64, 92). Embolic material (28, 62) may be inserted in the aneurysm (20) before or after positioning the device (50, 80, 110, 130). The device (50, 80, 110, 130) may have a first end (81, 111, 131), a second end (81, 112, 132) substantially opposite to the first end (81, 111, 131), and a plurality of filaments (84, 114, 134) extending between and coupled at the first end (81, 111, 131) and the second end (82, 112, 132). Such devices (50, 80, 110, 130) may be football shaped, pumpkin shaped, or twisted. The device (50) may include a plurality of loops (52) forming a generally spherical shape.
摘要翻译：通常为球形的血管重建装置（50,80,110,130）可永久定位在具有动脉瘤（20）的分叉（60）的传入和传出血管的交界处。在器件（50,80,110,130）在接合处定位以将器件（50,80,110,130）基本上符合结的形状之后，器件（50,80,110,130）充当用于抑制从动脉瘤（20）和装置（50,80,110,130）中的物体突出的脚手架允许灌注到传出血管。定位装置（50,80,110,130）可以包括从导管（64,92）的展开和机械或电解释放。栓塞材料（28,62）可以在定位装置（50,80,110,130）之前或之后插入到动脉瘤（20）中。装置（50,80,110,130）可以具有第一端（81,111,131），与第一端（81,111,131）基本相对的第二端（81,112,132），和多个长丝（84,114,134），其在第一端（81,111,131）和第二端（82,112,132）之间延伸并耦合在第一端（81,111,131）。这种装置（50,80,110,130）可以是足球形，南瓜形或扭曲的。装置（50）可以包括形成大致球形的多个环（52）。

10. 发明申请

WO2009014883A1 POWER SUPPLY USING TIME VARYING SIGNAL FOR ELECTROLYTICALLY DETACHING IMPLANTABLE DEVICE 审中-公开
标题翻译：使用时间变化信号的电源用于电动分离可植入装置
公开(公告)号：WO2009014883A1
公开(公告)日：2009-01-29
申请号：PCT/US2008/069238
申请日：2008-07-03
申请人： BOSTON SCIENTIFIC SCIMED, INC. , WILLIAMS, Michael , BASHIRI, Mehran , MERCHEL, Scott
发明人： WILLIAMS, Michael , BASHIRI, Mehran , MERCHEL, Scott
IPC分类号： A61B17/12
CPC分类号： A61B17/12022 , A61B17/12113 , A61B17/1214 , A61B2017/12063
摘要： A medical system comprises an implant assembly including an elongated pusher member, an implantable device (e.g., a vaso-occlusive device) mounted to the distal end of the pusher member, and an electrolytically severable joint disposed on the pusher member, wherein the implantable device detaches from the pusher member when the severable joint is severed, the medical system comprising an electrical power supply coupled to the implant assembly, and configured for conveying a time varying signal having net positive electrical energy to the severable joint to detach the implantable device from the pusher member.
摘要翻译：医疗系统包括植入组件，其包括细长的推动器构件，安装到推动器构件的远端的可植入装置（例如，血管闭塞装置）和设置在推动器构件上的可电解的关节，其中可植入装置当可分开的关节被切断时，该医疗系统包括耦合到植入组件的电源，并被配置为将具有净正电能的时变信号传送到可分开的接头以将可植入装置从推动员

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