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1. 发明申请

WO2019116313A1 GUIDEWIRE ASSEMBLY WITH OFFSET CORE WIRES 审中-公开
公开(公告)号：WO2019116313A1
公开(公告)日：2019-06-20
申请号：PCT/IB2018/060047
申请日：2018-12-13
申请人： ACCLARENT, INC.
发明人： MATLOCK, George L. , NGO-CHU, Don Q. , PHAM, Tuan , THINNES, JR., John H.
IPC分类号： A61M25/09
CPC分类号： A61M25/09041 , A61B1/01 , A61B1/07 , A61B5/065 , A61B17/24 , A61B34/10 , A61B34/20 , A61B90/30 , A61B90/37 , A61B2034/105 , A61B2034/107 , A61B2034/2051 , A61B2034/2065 , A61B2034/2072 , A61B2090/306 , A61B2090/365 , A61B2217/007 , A61M3/0295 , A61M25/0041 , A61M25/0113 , A61M25/09 , A61M25/09033 , A61M29/02 , A61M2025/0008 , A61M2025/0166 , A61M2025/0681 , A61M2025/09083 , A61M2025/09108 , A61M2025/09116 , A61M2025/0915 , A61M2025/09175 , A61M2025/09183 , A61M2029/025 , A61M2210/0681
摘要： An apparatus and method of manufacture includes a helical wire coil body having a proximal body end portion and a distal body end portion that extend along a longitudinal coil axis. The apparatus also includes a non-extensible, core wire assembly configured to inhibit longitudinal elongation of the helical wire coil body along the longitudinal coil axis. The core wire assembly has a first core wire and a second core wire respectively extending from the proximal body end portion toward the distal body end portion. The second core wire proximally terminates relative to the first core wire such that the distal body end portion is more flexible than the proximal body end portion. The first and second core wires transversely overlap to provide a collective column strength to the helical wire coil body along the longitudinal coil axis.

2. 发明申请

WO2011038522A1 FÜHRUNGSDRAHT 审中-公开
标题翻译：导丝
公开(公告)号：WO2011038522A1
公开(公告)日：2011-04-07
申请号：PCT/CH2010/000234
申请日：2010-09-29
申请人： SCHWAGER MEDICA , SCHWAGER, Michael
发明人： SCHWAGER, Michael
IPC分类号： A61M25/09
CPC分类号： A61M25/09 , A61M25/09016 , A61M25/09033 , A61M2025/09083 , A61M2025/091 , A61M2025/09175
摘要： Ein Führungsdraht (100) für einen Katheter, welcher zum Einbringen und/oder Entnehmen von Fluiden in menschlichen und/oder tierischen Hohlorganen, insbesondere in Blutgefässen, ausgelegt ist, umfassend einen länglichen Hohlschaft (110) mit einem Lumen (120) zum Zu- und/oder Abführen des Fluids, sowie eine koaxial an einem distalen Ende (117) des Hohlschafts (110) anschliessende Einführhilfe in Form einer flexiblen Drahtwendel (150) mit einer an einem distalen Ende (153) der Drahtwendel angeordneten Führungsdrahtspitze (170), wobei zur Steuerung einer Flexibilität des Führungsdrahts (100) im Lumen (120) des Hohlschafts (110) ein Kerndraht (130) angeordnet ist, welcher sich aus dem Lumen (120) heraus in einer longitudinalen Richtung durch die Drahtwendel (150) hindurch bis zur Führungsdrahtspitze (170) hin erstreckt, zeichnet sich dadurch aus, dass ein in einer proximalen Richtung an die Führungsdrahtspitze (170) angrenzender distaler Innenbereich (151) der Drahtwendel (150) über einen neben dem Kerndraht (150) ausgebildeten Fluidkanal (151, 161, 155) mit dem Lumen (120) des Hohlschafts (110) kommuniziert und über wenigstens eine nach aussen offene Durchlassöffnung (154) für das ein- und/oder auszubringende Fluid verfügt.
摘要翻译：用于导管，其被设计成用于在血管中引入和/或抽出流体到人体和/或动物的中空器官，特别是，包括具有内腔（120），用于供给和细长空心轴（110）的导线（100） /或排出流体，以及一个同轴地在空心轴中的柔性金属丝线圈（150）的形式（110）随后插入辅助用在设置在线圈导丝尖端（170）的远端（153），其中，所述的远端（117）控制在所述空心轴的内腔（120）的导引线（100）的弹性（110）的芯线（130）被布置成穿过延伸到导丝尖端（从所述腔（120）从在通过导线线圈的纵向方向（150） 170）朝向延伸，其特征在于，（（A（在近侧方向上导丝尖端170）相邻的远端内部分151）的金属丝线圈150的）形成在旁边的芯线（150）的流体通道（151，161，155）与中空轴（110）的内腔（120）进行通信，并经由至少一个向外敞开的通道开口（154），用于输入和/或auszubringende流体具有，

3. 发明申请

WO2009039063A1 WIRE GUIDE 审中-公开
标题翻译：电线指南
公开(公告)号：WO2009039063A1
公开(公告)日：2009-03-26
申请号：PCT/US2008/076396
申请日：2008-09-15
申请人： COOK INCORPORATED , WILSON-COOK MEDICAL INC. , WILLIAM COOK EUROPE APS , ELSESSER, James, C. , HRUSKA, Christopher, L. , WEEKS, Aaron , URBANSKI, Jason, C. , CARLSON, James, M. , DUCHARME, Richard, W. , JORGENSEN, Alex
发明人： ELSESSER, James, C. , HRUSKA, Christopher, L. , WEEKS, Aaron , URBANSKI, Jason, C. , CARLSON, James, M. , DUCHARME, Richard, W. , JORGENSEN, Alex
IPC分类号： A61M25/09
CPC分类号： A61M25/09033 , A61M25/09 , A61M2025/09083 , A61M2025/09108 , A61M2025/09175 , Y10T29/49 , Y10T29/49826
摘要： The present invention provides a wire guide (20) suitable for use in a body vessel, such as a peripheral vessel. The wire guide comprises a core member (22) and a first coiled member (40), each having proximal and distal ends. In one embodiment, the core member comprises at least one recessed portion (36), wherein the proximal end of the first coiled member is seated at least partially within the recessed portion to form a substantially flush exterior surface with the core member. The wire guide further preferably comprises a second coiled member (50) having proximal and distal ends, wherein the second coiled member is disposed distal to the first coiled member. The distal end of the first coiled member may be partially intertwined with the proximal end of. the second coiled member. A shaping ribbon (60) may be disposed substantially beneath the second coiled member to achieve a desired curvature at the distal tip of the wire guide.
摘要翻译：本发明提供一种适用于身体容器（例如外围血管）的导丝器（20）。线引导件包括芯构件（22）和第一螺旋构件（40），每个具有近端和远端。在一个实施例中，芯构件包括至少一个凹部（36），其中第一线圈构件的近端至少部分地位于凹部内，以形成与芯构件基本上齐平的外表面。线引导件还优选地包括具有近端和远端的第二线圈构件（50），其中第二线圈构件设置在第一线圈构件的远侧。第一线圈构件的远端可以与其近端部分地缠结。第二线圈构件。成形带（60）可以基本上设置在第二线圈构件的下方，以在导线器的远端获得期望的曲率。

4. 发明申请

WO2008085167A1 STEERABLE GUIDE WIRE WITH TORSIONALLY STABLE TIP 审中-公开
标题翻译：可转向导线，扭矩稳定
公开(公告)号：WO2008085167A1
公开(公告)日：2008-07-17
申请号：PCT/US2007/000650
申请日：2007-01-10
申请人： ST. JUDE MEDICAL, CARDIOLOGY DIVISION, INC. , RESSEMANN, Thomas, V. , KEITH, Peter, T. , WILLARD, Steven, N. , NESS, Peter, J. , HACKETT, Steven, S.
发明人： RESSEMANN, Thomas, V. , KEITH, Peter, T. , WILLARD, Steven, N. , NESS, Peter, J. , HACKETT, Steven, S.
IPC分类号： A61B5/00
CPC分类号： A61M25/09 , A61B17/12136 , A61B2017/003 , A61F2/013 , A61F2002/018 , A61F2230/0006 , A61F2230/0067 , A61M25/09033 , A61M2025/09083
摘要： A steerable guide wire includes a core wire having a proximal end and a distal end. A braided filament is affixed to the distal end of the core wire. An outer coil surrounds at least a portion of the core wire and the braided filament. A proximal end of the braided filament is secured to a distal end of the coil. By locating the braided filament in the distal tip portion of the guide wire, a guide wire is provided that is highly flexible, has a high degree of tensile integrity, and is highly steerable, even in tortuous vasculature. Filter and balloon catheters having braided filaments at the distal end are also described.
摘要翻译：可导向的导丝线包括具有近端和远端的芯线。编织丝固定在芯线的远端。外部线圈围绕芯线和编织细丝的至少一部分。编织细丝的近端固定到线圈的远端。通过将编织丝定位在导丝的远侧末端部分，提供了一种导丝，其具有高柔性，高度的拉伸完整性，并且即使在曲折的脉管系统中也是高度可操纵的。还描述了在远端具有编织细丝的过滤器和球囊导管。

5. 发明申请

WO2008024597A2 ELONGATE MEDICAL DEVICE INCLUDING DEFORMABLE DISTAL END 审中-公开
标题翻译：最近的医疗设备，包括可变的远端
公开(公告)号：WO2008024597A2
公开(公告)日：2008-02-28
申请号：PCT/US2007/074648
申请日：2007-07-27
申请人： BOSTON SCIENTIFIC SCIMED, INC. , HIRSHMAN, Peter
发明人： HIRSHMAN, Peter
IPC分类号： A61F2/06 , A61L31/02 , A61M25/00
CPC分类号： A61M25/09 , A61L29/02 , A61L31/022 , A61L31/14 , A61L2400/16 , A61M25/0041 , A61M25/0051 , A61M25/008 , A61M25/09033 , A61M2025/09075 , A61M2025/09108 , A61M2025/09133 , A61M2025/09141 , A61M2025/0915
摘要： An intracorporeal device includes an elongate tubular member. The tubular member can comprise one or more materials that have superelastic and/or shape memory characteristics. The tubular member can comprise one or more deformable zones and one or more elastic zones. The deformable zone(s) can comprise material(s) that are less elastic than the material in the elastic zone(s). The deformable and elastic zones can contain different materials or they can contain the same or similar materials that have been treated in order to change the elasticity or type of elasticity of one of the zones relative to the other zones, creating different elasticity between the elastic and the deformable zones. The intracorporeal device can be, for example, a guidewire, a catheter or any other intracorporeal device that can include an elongate tubular member.
摘要翻译：体内装置包括细长的管状构件。管状构件可以包括具有超弹性和/或形状记忆特性的一种或多种材料。管状构件可以包括一个或多个可变形区和一个或多个弹性区。可变形区域可以包括比弹性区域中的材料弹性小的材料。可变形和弹性区域可以包含不同的材料，或者它们可以包含已经被处理以相对于其它区域改变其中一个区域的弹性或弹性类型的相同或相似的材料，从而在弹性和可变形区域。体内装置可以是例如导丝，导管或可以包括细长管状构件的任何其它体内装置。

6. 发明申请

WO2004018032A1 CRIMP AND CUT TOOL FOR SEALING AND UNSEALING GUIDE WIRES AND TUBULAR INSTRUMENTS 审中-公开
标题翻译：密封和剥离指南针和管件仪器的切割和切割工具
公开(公告)号：WO2004018032A1
公开(公告)日：2004-03-04
申请号：PCT/US2003/026772
申请日：2003-08-25
申请人： KENSEY NASH CORPORATION
发明人： FISHER, William, T. , NASH, John, E. , SAURO, Dennis, M. , EBERHART, Mark
IPC分类号： A61M25/10
CPC分类号： A61M25/10184 , A61M25/09033 , A61M25/10182 , A61M25/10185 , A61M25/104 , A61M2025/105
摘要： An apparatus for modulating the pressure of a fluid such as a gas within the expandable portion (11) of a guide wire catheter (12). A preferred embodiment apparatus features a means (19) for controllably gripping and releasing the open, proximal end of a tubular guide wire, means (44) for introducing a fluid to a desired pressure and volume into the expandable portion of the tubular guide wire through the open end, and, while maintaining the pressure and volume of fluid in the tubular guide wire, a means (23) for introducing a sealing member (22) into the open end of said tubular guide wire to seal the fluid in the tubular guide wire. In a particularly preferred embodiment, the apparatus also features a deflation tool (53) for piercing the seal and letting the fluid out. Using this apparatus, the tubular guide wire can be re-sealed and re-opened as necessary.
摘要翻译：一种用于调节诸如在导丝导管（12）的可膨胀部分（11）内的气体的流体的压力的装置。优选的实施例装置具有用于可控地夹紧和释放管状导丝的开口近端的装置（19），用于将流体引导到期望的压力和体积进入管状导丝通过的可扩张部分的装置（44）开口端，并且在保持管状导丝中的流体的压力和体积的同时，将用于将密封构件（22）引入所述管状导丝的开口端的装置（23）以密封管状引导件线。在特别优选的实施例中，该装置还具有用于刺穿密封件并使流体流出的放气工具（53）。使用这种装置，可以根据需要重新密封和重新打开管状导丝。

7. 发明申请

WO2004018031A2 GUIDE WIRE 审中-公开
标题翻译：指南
公开(公告)号：WO2004018031A2
公开(公告)日：2004-03-04
申请号：PCT/US2003/026321
申请日：2003-08-21
申请人： WILLIAM A. COOK AUSTRALIA PTY. LTD. , COOK INCORPORATED , WILLIAM COOK EUROPE APS
发明人： HARTLEY, David, Ernest , CHRISTIANSEN, Frank, Karhu
IPC分类号： A61M25/01
CPC分类号： A61M25/09 , A61M25/0041 , A61M25/09033 , A61M2025/09083 , A61M2025/09133 , A61M2025/0915 , A61M2025/09175
摘要： A guide wire (1) to assist percutaneous endovascular deployment which has zones of varying stiffness. An elongate central zone (3) of high stiffness, a proximal zone (4) of transition from high stiffness to semi-stiffness and a distal zone (5) of transition from high stiffness to being relatively flexible. The distal zone (5) has three zones, a semi stiff zone (11) adjacent the central zone, a transition zone (13) being of flexibility of from semi-stiff extending to flexible and a tip zone (15) being of high flexibility. The distal tip has a small J curve (16) to ensure that it is atraumatic in vessels and to prevent damage to the aortic heart valve. The distal zone (5) can also have a large curve to assist with anchoring the guide wire into the aortic arch.
摘要翻译：导丝（1）用于辅助经皮血管内部署，其具有不同刚度的区域。具有高刚度的细长中心区域（3），从高刚度到半刚性转变的近端区域（4）以及从高刚度转变到相对柔韧的远端区域（5）。远侧区域（5）具有三个区域，邻近中央区域的半刚性区域（11），具有从半刚性延伸到柔性的柔性的过渡区域（13）以及具有高柔性的尖端区域（15）。远端尖端有一个小的J曲线（16），以确保它在血管内无创伤并防止损伤主动脉心脏瓣膜。远端区域（5）也可以具有大的弯曲以协助将导丝锚定到主动脉弓中。

8. 发明申请

WO99026692A1 LOW PROFILE CATHETER VALVE AND INFLATION ADAPTOR 审中-公开
标题翻译：低剖面导管阀和充气适配器
公开(公告)号：WO99026692A1
公开(公告)日：1999-06-03
申请号：PCT/US1998/024947
申请日：1998-11-20
IPC分类号： A61M25/01 , A61F2/958 , A61M25/00 , A61M25/16 , A61M29/02 , A61M39/00 , A61M29/00
CPC分类号： A61M25/10185 , A61M25/0009 , A61M25/0026 , A61M25/0054 , A61M25/0075 , A61M25/09 , A61M25/09033 , A61M25/10 , A61M25/104 , A61M2025/0018 , A61M2025/09008 , A61M2025/09175 , A61M2025/1015 , A61M2025/1052 , A61M2025/1079 , A61M2025/1093
摘要： A low profile catheter valve comprising a movable sealer portion (30) is positioned within the inflation lumen (40) of a catheter. The sealer portion (30) forms a fluid tight seal with the inflation lumen (40) by firmly contacting the entire circumference of a section of the inflation lumen (40). The sealer portion (30) may be positioned proximally of a side-access inflation port (22) on the catheter, to extablish an unrestricted fluid pathway between the inflation port (22) and an inflatable balloon (20) on the distal end of the catheter. As desired, the clinician may move the sealer portion (30) to a position distal of the inflation port (22), thereby preventing any fluid from being introduced into or withdrawn from the balloon (2) via the inflation port (22). An inflation adaptor (200) moves the sealer portion (30) within the catheter to establish or close the fluid pathway between the inflation port (22) and the inflatable balloon (20). In use, the catheter is placed into the adaptor (200) with the sealer portion (30) to a second position which allows passage of fluid into the inflation lumen (40). An actuator (220) on the adaptor (200) is used to drive the sealer portion (30) to a second position which allows passage of fluid into the inflation lumen (40). The balloon (20) is then inflated and the actuator (220) is used to move the sealer portion (30) to again block the inflation lumen (40). The adaptor (200) is configured to allow the sealer portion (30) to be driven to a third position which is further from the inflation port (22) than the first position.
摘要翻译：包括可移动密封部分（30）的薄型导管阀定位在导管的充气腔（40）内。密封器部分（30）通过牢固地接触充气腔（40）的一部分的整个周边与充气腔（40）形成流体密封。密封器部分（30）可以位于导管上的侧向通气口（22）的近侧，以便在充气口（22）和膨胀口（22）的远端上的可充气气囊（20）之间提供不受限制的流体通道导管。根据需要，临床医生可以将密封部分（30）移动到充气端口（22）的远侧位置，从而防止任何流体经由充气口（22）被引入或从气囊（2）中排出。充气适配器（200）使密封件部分（30）在导管内移动以建立或关闭充气口（22）和可膨胀气囊（20）之间的流体通路。在使用中，导管被放置到具有密封件部分（30）的适配器（200）中，允许流体进入充气腔（40）的第二位置。适配器（200）上的致动器（220）用于将密封件部分（30）驱动到允许流体进入膨胀内腔（40）的第二位置。然后使气囊（20）膨胀，致动器（220）用于移动密封件部分（30）以再次阻塞膨胀内腔（40）。适配器（200）构造成允许密封件部分（30）被驱动到比充气端口（22）更远离第一位置的第三位置。

9. 发明申请

WO9744085A3 Low profile catheter valve 审中-公开
标题翻译：薄型导管阀
公开(公告)号：WO9744085A3
公开(公告)日：1998-09-17
申请号：PCT/US9708469
申请日：1997-05-19
申请人： PERCUSURGE INC
发明人： ZADNO-AZIZI GHOLAM-REZA , MORANO-FORD APRIL A , BAGAOISAN CELSO J , BLEAM JEFFREY C , KIM ISAAC J , FIELD JEFFREY F
IPC分类号： A61M39/00 , A61F2/958 , A61M25/00 , A61M25/01 , A61M25/16 , A61M29/02 , A61M25/10
CPC分类号： A61M25/10185 , A61M25/0009 , A61M25/0026 , A61M25/0054 , A61M25/0075 , A61M25/09 , A61M25/09033 , A61M25/10 , A61M25/104 , A61M2025/0018 , A61M2025/09008 , A61M2025/09175 , A61M2025/1015 , A61M2025/1052 , A61M2025/1079 , A61M2025/1093
摘要： Disclosed herein is a low profile catheter valve comprising a movable sealer portion positioned within the inflation lumen of a catheter. The sealer portion forms a fluid tight seal with the inflation lumen by firmly contacting the entire circumference of a section of the inflation lumen. The sealer portion may be positioned proximally of a side-access inflation port on the catheter, to establish an unrestricted fluid pathway between the inflation port and an inflatable balloon on the distal end of the catheter. As desired, the clinician may move the sealer portion to a position distal of the inflation port, thereby preventing any fluid from being introduced into or withdrawn from the balloon via the inflation port.

10. 发明申请

WO98039047A1 ASPIRATION SYSTEM AND METHOD 审中-公开
标题翻译：吸引系统和方法
公开(公告)号：WO98039047A1
公开(公告)日：1998-09-11
申请号：PCT/US1998/004494
申请日：1998-03-06
IPC分类号： A61B17/22 , A61B18/24 , A61F2/958 , A61M1/00 , A61M25/00 , A61M29/02 , A61M25/10
CPC分类号： A61M25/0009 , A61B17/22 , A61B18/245 , A61B2017/22067 , A61B2017/22084 , A61B2017/320716 , A61B2217/005 , A61M25/0029 , A61M25/005 , A61M25/0053 , A61M25/0054 , A61M25/0075 , A61M25/09 , A61M25/09033 , A61M25/10 , A61M25/1011 , A61M25/10184 , A61M25/104 , A61M2025/0018 , A61M2025/0034 , A61M2025/0037 , A61M2025/0183 , A61M2025/09008 , A61M2025/09175 , A61M2025/09183 , A61M2025/1015 , A61M2025/1052 , A61M2025/1079 , A61M2025/109 , A61M2025/1093
摘要： Aspiration catheters and methods for the treatment of an occlusion in a blood vessel. These catheters and methods are especially useful in the removal of occlusions from saphenous vein grafts, the coronary and carotid arteries, arteries above the aortic arch and even smaller vessels. The catheters (10) of the present invention are provided in either over-the-wire or in single operator form. Radiopaque markers are preferably incorporated into distal ends (22) of the catheters, and visual markers are incorporated into the proximal end of the catheters, to facilitate their positioning within the body. The catheters are provided with varying flexibility along the length of the shaft, such that they are soft and flexible enough to be navigated through the vasculature of a patient without causing damage, but are stiff enough to sustain the axial push required to position the catheter properly and to sustain the aspiration pressures. Support mandrels (16a and b) and support sheaths (140) may also be added to impart additional strength to the length of the catheter.
摘要翻译：吸入导管和用于治疗血管闭塞的方法。这些导管和方法特别适用于去除隐静脉移植物，冠状动脉和颈动脉，主动脉弓上方的动脉甚至更小的血管的闭塞。本发明的导管（10）以线上或单个操作者形式提供。不透射线的标记优选并入到导管的远端（22）中，并且视觉标记被并入导管的近端，以便于它们在体内的定位。导管沿着轴的长度设置有不同的柔性，使得它们柔软且足够柔韧，可以通过患者的脉管系统导航而不造成损伤，但足够坚硬以维持正确定位导管所需的轴向推动并维持吸引压力。还可以加入支撑心轴（16a和b）和支撑护套（140）以赋予导管长度的附加强度。

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