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1. 发明申请

WO2010128399A2 LOW-DEAD VOLUME MICROFLUIDIC CIRCUIT AND METHODS 审中-公开
标题翻译：低死亡体积微流体电路和方法
公开(公告)号：WO2010128399A2
公开(公告)日：2010-11-11
申请号：PCT/IB2010001211
申请日：2010-05-05
申请人： CEQUR SA , GRAVESEN PETER , ARNDT HEIKO
发明人： GRAVESEN PETER , ARNDT HEIKO
IPC分类号： A61M5/158 , A61M5/142 , F15C5/00 , F16K99/00 , G01L9/00
CPC分类号： G01L19/0007 , A61M5/141 , A61M5/142 , A61M5/14248 , A61M5/152 , A61M5/158 , A61M2005/1405 , A61M2005/14252 , A61M2206/20 , B01L2200/0605 , B01L2300/14 , B01L2400/0633 , F04B19/006 , Y10T137/0402
摘要： A method is described for reducing a dead volume of a microfluidic circuit that includes, in one embodiment, a reservoir, an outlet, and a microfluidic flowpath fluidly connecting the reservoir and the outlet. The method includes providing a microfluidic flow component between the reservoir and the outlet for performing a function and in fluidic communication with the microfluidic flowpath, wherein the microfluidic flow component includes a total volume including a working volume and a dead volume. The working volume is a volume necessary for the microfluidic flow component to perform the function and the dead volume is a volume unnecessary for the microfluidic flow component to perform the function. The method includes configuring at least one of the reservoir, the microfluidic flowpath, and the microfluidic flow component to reduce the dead volume, such that the working volume of the component is substantially the same as the total volume.
摘要翻译：描述了一种用于减少微流体回路的死体积的方法，其在一个实施例中包括流体连接储存器和出口的储存器，出口和微流体流路。该方法包括在储存器和出口之间提供微流体流动部件，用于执行功能并与微流体流动路径流体连通，其中微流体流动部件包括包括工作容积和死体积的总体积。工作体积是微流体流动部件执行功能所需的体积，并且死体积是微流体流动部件执行功能所不需要的体积。该方法包括配置储存器，微流体流路和微流体流动分量中的至少一个以减少死体积，使得部件的工作体积基本上与总体积相同。

2. 发明申请

WO2007048410A1 A FLOW SYSTEM AND A MICRO FLUIDIC SYSTEM COMPRISING A FLOW SYSTEM 审中-公开
标题翻译：流动系统和包含流动系统的微流体系统
公开(公告)号：WO2007048410A1
公开(公告)日：2007-05-03
申请号：PCT/DK2006/000593
申请日：2006-10-24
申请人： Danfoss A/S , DIRAC, Holger , GRAVESEN, Peter , SCHWEITZ, Kasper Oktavio
发明人： DIRAC, Holger , GRAVESEN, Peter , SCHWEITZ, Kasper Oktavio
IPC分类号： G05D7/01 , F16K31/00
CPC分类号： G05D7/0186 , F16K31/002 , F16K99/0001 , F16K99/0026 , F16K99/0036 , F16K99/0061 , F16K2099/0084 , F16K2099/0086 , Y10T137/1963 , Y10T137/206 , Y10T137/2224
摘要： A flow system (1) comprising a first part (2) and a second part (3), the parts (2, 3) being made from materials having different coefficients of thermal expansion. The first (2) and second (3) parts are positioned relatively to each other in such a way that when the ambient temperature changes corresponding changes are caused in a flow channel (4) formed in the first part (2), thereby changing the flow resistance of the flow channel (4). Thereby a change in flow resistance caused by a change in viscosity of a fluid being transported by the flow system (1) can be counteracted. The resulting flow resistance of the flow system (1) is thereby at least substantially independent of the ambient temperature. Furthermore, a micro fluidic system comprising the flow system (1). The micro fluidic system may be or form part of a medical device, a fluid analysis system, e.g. a device for measuring blood glucose levels of blood samples, or an infusion device.
摘要翻译：一种包括第一部分（2）和第二部分（3）的流动系统（1），所述部分（2,3）由具有不同热膨胀系数的材料制成。第一（2）和第二（3）部分彼此相对定位，使得当在形成在第一部分（2）中的流动通道（4）中引起环境温度变化时，引起相应的变化，从而改变流动通道（4）的流动阻力。由此，可以抵消由流动系统（1）输送的流体的粘度变化引起的流动阻力的变化。因此，流动系统（1）的所得流动阻力至少基本上与环境温度无关。此外，包括流动系统（1）的微流体系统。微流体系统可以是或形成医疗装置的一部分，流体分析系统，例如，用于测量血液样本的血糖水平的装置或输注装置。

3. 发明申请

WO2005111629A1 MICROANALYSIS APPARATUS WITH CONSTANT PRESSURE PUMP SYSTEM 审中-公开
标题翻译：具有恒压泵系统的微观分析装置
公开(公告)号：WO2005111629A1
公开(公告)日：2005-11-24
申请号：PCT/DK2005/000321
申请日：2005-05-13
申请人： DANFOSS A/S , GRAVESEN, Peter
发明人： GRAVESEN, Peter
IPC分类号： G01N35/08
CPC分类号： G01N35/085 , A61B5/14532 , B01F13/0072 , B01F13/0093
摘要： Micro-analysis system for analysing species with a fluid medium, said system containing sensing means for collecting species from the medium, said sensing means having an inlet and an outlet, analysing means comprising a channel, said channel defining at least one part for mixing, at least one part for reacting and at least one part for measuring detecting arrangement for determining the concentration of species at said part for measuring, a first fluid reservoir holding carrier fluid and at least one second fluid reservoir holding reagent fluid, connecting means, comprising first connecting means for fluid connection between the first fluid reservoir and the analysing means, second connecting means for fluid connection between the second fluid reservoir and the inlet of the sensing means and third connecting means for fluid connection between the outlet of the sensing means and the analysing means, said first connecting means comprising at least one first flow restricting means and said second connecting means comprising at least one second flow restricting means characterised by said micro-analysis system further comprising storage means containing said first fluid reservoir and said second fluid reservoir, said storage means being in downstream flow connection with means for pressurizing said fluid reservoirs, said storage means and said pressurizing means being separated from said analysing means.
摘要翻译：用于用流体介质分析物种的微分析系统，所述系统包含用于从介质收集物质的感测装置，所述感测装置具有入口和出口，包括通道的分析装置，所述通道限定至少一个用于混合的部分，用于反应的至少一个部分和用于测量用于测量所述部分处的物质浓度的检测装置的至少一个部分，第一流体储存器保持载体流体和至少一个第二流体储存器保持试剂流体，连接装置，包括第一用于在第一流体储存器和分析装置之间流体连接的连接装置，用于在第二流体储存器和感测装置的入口之间流体连接的第二连接装置和用于感测装置的出口和分析装置之间的流体连接的第三连接装置装置，所述第一连接装置包括至少一个第一流动限制装置和sa id第二连接装置，包括至少一个第二流动限制装置，其特征在于所述微分析系统还包括容纳所述第一流体储存器和所述第二流体储存器的存储装置，所述存储装置与用于对所述流体储存器加压的装置处于下游流动连接，所述存储装置和所述加压装置与所述分析装置分离。

4. 发明申请

WO2004025156A1 CONTROL VALVE WITH ELASTOMERIC VALVE ELEMENT 审中-公开
标题翻译：带有弹性阀元件的控制阀
公开(公告)号：WO2004025156A1
公开(公告)日：2004-03-25
申请号：PCT/DK2003/000593
申请日：2003-09-12
申请人： DANFOSS A/S , ARNDT, Heiko , GRAVESEN, Peter
发明人： ARNDT, Heiko , GRAVESEN, Peter
IPC分类号： F16K7/20
CPC分类号： F16K7/20
摘要： This invention relates to control valves for controlling of fluid flow, where the flow-controlling element in the valve body is of an elastomeric material. The control valve has only one flow-controlling element, which element fulfils all functions of the valve, meaning non-return function, flow-restriction function and/or controlling function.
摘要翻译：本发明涉及用于控制流体流动的控制阀，其中阀体中的流动控制元件是弹性材料。控制阀只有一个流量控制元件，该元件满足阀的所有功能，意味着非返回功能，流量限制功能和/或控制功能。

5. 发明申请

WO2003068294A3 DEVICE FOR ADMINISTERING OF MEDICATION IN FLUID FORM 审中-公开
公开(公告)号：WO2003068294A3
公开(公告)日：2003-08-21
申请号：PCT/DK2003/000107
申请日：2003-02-18
申请人： DANFOSS A/S , GRAVESEN, Peter , RASMUSSEN, Per, Brandt , DIRAC, Holger
发明人： GRAVESEN, Peter , RASMUSSEN, Per, Brandt , DIRAC, Holger
IPC分类号： A61M5/142
摘要： An infusion device for continously infusion of medication is disclosed, in which infusion is controlled over two separate fluid communications. The infusion is in each fluid communication controlled by restricting means and valve means, and one of the fluid communications further contains a holding device for bolus rate of infusion for a short period. The devide comprises a flow regulating device comprising a passage defined by at lesat a first element is a primary deformable element adapted to be elastically deformed so as to change the cross sectional area of the passage. Furthermore the device comprises a container for storage and supply of a medication in fluid form, said container comprising a first and a second chamber being arranged relatively to each other so that when volume of the first chamber increases the volume of the second chamber decreases.

6. 发明申请

WO2012054741A1 METHODS AND SYSTEMS FOR DOSING A MEDICAMENT 审中-公开
标题翻译：用于治疗药物的方法和系统
公开(公告)号：WO2012054741A1
公开(公告)日：2012-04-26
申请号：PCT/US2011/057123
申请日：2011-10-20
申请人： CEQUR SA , BOIT, Christopher, Sprague , GRAVESEN, Peter , ARNDT, Heiko , PEATFIELD, Gregory, H. , MCDERMOTT, Patrick
发明人： BOIT, Christopher, Sprague , GRAVESEN, Peter , ARNDT, Heiko , PEATFIELD, Gregory, H. , MCDERMOTT, Patrick
IPC分类号： A61M5/142 , A61M5/145
CPC分类号： A61M5/1424 , A61M5/141 , A61M5/1413 , A61M5/14248 , A61M5/148 , A61M5/16809 , A61M5/3153 , A61M5/3157 , A61M39/223 , A61M2005/3123 , A61M2039/224 , A61M2205/3331 , A61M2205/581 , A61M2205/582 , A61M2205/583
摘要： A manually actuated pump (400), such as a bolus delivery circuit of an insulin pump, combines a direct drive piston system (404) with a lost motion valve system (406), to deliver reliably a full bolus dose, while precluding partial dosing or inadvertent overdosing conditions. The pump may also include a signaling device (407) to indicate when a full bolus dose is delivered.
摘要翻译：手动致动泵（400），例如胰岛素泵的推注输送电路，将直接驱动活塞系统（404）与空动阀系统（406）组合，以可靠地递送完全推注剂量，同时排除部分给药或无意的过量条件。泵还可以包括用于指示何时输送完全推注剂量的信号装置（407）。

7. 发明申请

WO2011022250A3 MEDICINE DELIVERY DEVICE HAVING DETACHABLE PRESSURE SENSING UNIT 审中-公开
公开(公告)号：WO2011022250A3
公开(公告)日：2011-09-22
申请号：PCT/US2010044996
申请日：2010-08-10
申请人： CEQUR SA , PEATFIELD GREG , GRAVESEN PETER , ARNDT HEIKO , CHIRIAEV SERGUEI
发明人： PEATFIELD GREG , GRAVESEN PETER , ARNDT HEIKO , CHIRIAEV SERGUEI
IPC分类号： A61M5/14 , A61M5/142 , A61M5/145 , A61M5/152 , A61M5/168
CPC分类号： A61M5/5086 , A61M5/14 , A61M5/1413 , A61M5/14248 , A61M5/16831 , A61M5/16854 , A61M5/16886 , A61M2005/14252 , A61M2005/14264 , A61M2005/14268 , A61M2005/16863 , A61M2205/0244 , A61M2205/18 , A61M2205/3331 , A61M2205/3334 , A61M2205/3344 , A61M2205/3358 , A61M2205/50 , A61M2205/581 , A61M2205/582 , A61M2205/583 , A61M2205/587 , A61M2205/70 , A61M2207/00
摘要： A fluid medicament delivery device includes a patient attachment unit, containing the fluid medicament, and an indicator unit adapted to be detachably coupled to the patient attachment unit. A method for monitoring the fluid medicament includes independently setting a flow rate of a fluid medicament with the patient attachment unit. A pressure and/or a flow rate of the fluid medicament is sensed with a sensor located in a separate indicator unit in a sensing mode. A status of the fluid medicament delivery device is determined based at least in part on the pressure and/or the flow rate.

8. 发明申请

WO2008052559A3 A DIELECTRIC COMPOSITE AND A METHOD OF MANUFACTURING A DIELECTRIC COMPOSITE 审中-公开
标题翻译：一种介电复合材料和一种制造介电复合材料的方法
公开(公告)号：WO2008052559A3
公开(公告)日：2009-03-19
申请号：PCT/DK2007000474
申请日：2007-11-02
申请人： DANFOSS AS , BENSLIMANE MOHAMED YAHIA , GRAVESEN PETER
发明人： BENSLIMANE MOHAMED YAHIA , GRAVESEN PETER
IPC分类号： H02N1/00 , H01L41/27 , H01L41/333 , H01L41/45
CPC分类号： H02N1/006 , H01L41/083 , H01L41/0836 , H01L41/0986 , H01L41/27 , H01L41/333 , H01L41/45
摘要： The invention provides a composite comprising a film made of a dielectric material. The film has a first surface and second surface, and at least the first surface comprises a surface pattern of raised and depressed surface portions. Furthermore, the film comprises a first electrically conductive layer being deposited onto the surface pattern. The electrically conductive layer has a corrugated shape which is formed by the surface pattern of the film. Thus, the present invention relates to micromechanical design of a composite substantially modifying its macro-electro-mechanical properties.
摘要翻译：本发明提供一种复合材料，其包括由电介质材料制成的膜。薄膜具有第一表面和第二表面，并且至少第一表面包括凸起和凹陷的表面部分的表面图案。此外，膜包括沉积在表面图案上的第一导电层。导电层具有由膜的表面图案形成的波纹形状。因此，本发明涉及复合材料的微机械设计，其基本上改变其宏观机电性能。

9. 发明申请

WO2007143992A1 A PUMP 审中-公开
标题翻译：一个PUMP
公开(公告)号：WO2007143992A1
公开(公告)日：2007-12-21
申请号：PCT/DK2007/000281
申请日：2007-06-12
申请人： DANFOSS A/S , GRAVESEN, Peter , NYBERG, René Bøgelund
发明人： GRAVESEN, Peter , NYBERG, René Bøgelund
IPC分类号： F04B43/02 , F04B43/04
CPC分类号： F04B43/043 , F04B43/021
摘要： The invention provides a membrane pump e.g. for a mini or micro channel system. The pump has a fluid conduit from an inlet through a displacement chamber with a variable volume to an outlet. The conduit is formed in a first component, and a displacement actuation structure adapted to affect volume change of the displacement chamber as well as an upstream and a downstream valve structure adapted force the fluid in one direction are separated from the fluid and detachably attachable to an outer surface of a first component which forms the fluid conduit. The invention therefore facilitate a simple and reliable pump of which some components can be reused while one component which is contaminated by the pumped fluid, can be disposed of.
摘要翻译：本发明提供一种膜泵例如用于微型或微型通道系统。泵具有从入口通过具有可变容积到出口的容积室的流体导管。导管形成在第一部件中，并且适于影响位移室的体积变化的位移致动结构以及适于将流体沿一个方向推动的上游和下游阀结构与流体分离并且可拆卸地附接到形成流体导管的第一部件的外表面。因此，本发明便于简单可靠的泵，其中一些部件可被重复使用，而被泵送的流体污染的一个部件可以被处理。

10. 发明申请

WO2004074797A1 STRUCTURE FOR SHEAR FORCE SENSING 审中-公开
标题翻译：剪切力传感结构
公开(公告)号：WO2004074797A1
公开(公告)日：2004-09-02
申请号：PCT/DK2004/000122
申请日：2004-02-24
申请人： DANFOSS A/S , BENSLIMANE, Mohamed Yahia , GRAVESEN, Peter
发明人： BENSLIMANE, Mohamed Yahia , GRAVESEN, Peter
IPC分类号： G01L1/14
CPC分类号： G01L1/142
摘要： This invention relates generally to elastomeric sensors of the type where two electrodes are placed on opposite sides of an elastomeric corrugated core. More specifically, this invention relates to the application of such sensors as a shear force sensor structure. It is a task of this invention to disclose a device, by means of which elastomeric sensors can be used for sensing shear forces.
摘要翻译：本发明大体上涉及这样一种类型的弹性体传感器，其中两个电极放置在弹性波纹芯的相对侧上。更具体地，本发明涉及这种传感器作为剪切力传感器结构的应用。本发明的任务是公开一种装置，通过该装置可以使用弹性体传感器来感测剪切力。

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