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61. 发明申请

WO2013061169A2 ANTENNA PROVIDING VARIABLE COMMUNICATION WITH AN IMPLANT 审中-公开
标题翻译：天线提供具有植入物的可变通信
公开(公告)号：WO2013061169A2
公开(公告)日：2013-05-02
申请号：PCT/IB2012/003013
申请日：2012-09-28
申请人： MASHIACH, Adi , MUELLER, Carsten
发明人： MASHIACH, Adi , MUELLER, Carsten
IPC分类号： A61N1/05
CPC分类号： A61N1/36075 , A61B5/0031 , A61B5/11 , A61B5/113 , A61B5/4519 , A61B5/4818 , A61B5/682 , A61B5/6822 , A61B5/6833 , A61B5/6876 , A61B2562/164 , A61F5/566 , A61N1/05 , A61N1/0504 , A61N1/0514 , A61N1/0526 , A61N1/0529 , A61N1/0548 , A61N1/0551 , A61N1/0553 , A61N1/36 , A61N1/36003 , A61N1/3601 , A61N1/3605 , A61N1/36057 , A61N1/3606 , A61N1/3611 , A61N1/36117 , A61N1/36125 , A61N1/36135 , A61N1/36139 , A61N1/36146 , A61N1/37211 , A61N1/37223 , A61N1/37229 , A61N1/37235 , A61N1/37264 , A61N1/3727 , A61N1/3756 , A61N1/3787 , A61N2/006 , A61N2/02 , F04C2270/0421
摘要： A device may include a primary antenna configured to be located external to a subject and at least one processor in electrical communication with the primary antenna. The at least one processor may be configured to cause transmission of a primary signal from the primary antenna to an implantable device, wherein the implantable device includes at least one pair of modulation electrodes. The at least one processor may be further configured to adjust one or more characteristics of the primary signal to generate a sub-modulation control signal adapted so as not to cause a neuromuscular modulation inducing current at the at least one pair of modulation electrodes when received by the implantable device and to generate a modulation control signal adapted so as to cause a neuromuscular modulation inducing current at the at least one pair of modulation electrodes when received by the implantable device.
摘要翻译：设备可以包括被配置为位于对象外部的主天线以及与主天线电通信的至少一个处理器。所述至少一个处理器可以被配置为使得主信号从主天线传输到可植入装置，其中所述可植入装置包括至少一对调制电极。所述至少一个处理器还可以被配置为调整所述主信号的一个或多个特性以产生辅调制控制信号，所述子调制控制信号适于不会在由所述至少一对调制电极接收时在所述至少一对调制电极处引起神经肌肉调制感应电流并且产生调制控制信号，所述调制控制信号适于在由所述可植入装置接收时在所述至少一对调制电极处引起神经肌肉调制感应电流。

62. 发明申请

WO2013057594A2 APPARATUS AND METHOD TO CONTROL AN IMPLANT 审中-公开
标题翻译：装置和控制植入物的方法
公开(公告)号：WO2013057594A2
公开(公告)日：2013-04-25
申请号：PCT/IB2012002920
申请日：2012-09-28
申请人： MASHIACH ADI
发明人： MASHIACH ADI
IPC分类号： A61N1/02
CPC分类号： A61N1/36075 , A61B5/0031 , A61B5/11 , A61B5/113 , A61B5/4519 , A61B5/4818 , A61B5/682 , A61B5/6822 , A61B5/6833 , A61B5/6876 , A61B2562/164 , A61F5/566 , A61N1/05 , A61N1/0504 , A61N1/0514 , A61N1/0526 , A61N1/0529 , A61N1/0548 , A61N1/0551 , A61N1/0553 , A61N1/36 , A61N1/36003 , A61N1/3601 , A61N1/3605 , A61N1/36057 , A61N1/3606 , A61N1/3611 , A61N1/36117 , A61N1/36125 , A61N1/36135 , A61N1/36139 , A61N1/36146 , A61N1/37211 , A61N1/37223 , A61N1/37229 , A61N1/37235 , A61N1/37264 , A61N1/3727 , A61N1/3756 , A61N1/3787 , A61N2/006 , A61N2/02 , F04C2270/0421
摘要： A device according to some embodiments of the present disclosure includes a housing configured to retain a battery, a primary antenna associated with the housing, and at least one processor in electrical communication with the battery and the primary antenna. In some embodiments, the at least one processor may be configured to cause transmission of a primary signal from the primary antenna to an implantable device during a treatment session of at least three hours in duration, wherein the primary signal is generated using power supplied by the battery and includes a pulse train, the pulse train including a plurality of modulation pulses.
摘要翻译：根据本公开的一些实施例的装置包括被配置为保持电池，与壳体相关联的主天线以及与电池和主天线电连通的至少一个处理器的壳体。在一些实施例中，所述至少一个处理器可以被配置为在持续时间为至少三个小时的治疗期间期间使主信号从主天线传输到可植入装置，其中使用由电池并且包括脉冲串，所述脉冲串包括多个调制脉冲。

63. 发明申请

WO2013046042A2 APPARATUS AND METHOD FOR EXTENDING IMPLANT LIFE USING A DUAL POWER SCHEME 审中-公开
标题翻译：使用双电源方案延长植入生活的装置和方法
公开(公告)号：WO2013046042A2
公开(公告)日：2013-04-04
申请号：PCT/IB2012002391
申请日：2012-09-28
申请人： MASHIACH ADI , MUELLER CARSTEN
发明人： MASHIACH ADI , MUELLER CARSTEN
IPC分类号： A61N1/05
CPC分类号： A61N1/36075 , A61B5/0031 , A61B5/11 , A61B5/113 , A61B5/4519 , A61B5/4818 , A61B5/682 , A61B5/6822 , A61B5/6833 , A61B5/6876 , A61B2562/164 , A61F5/566 , A61N1/05 , A61N1/0504 , A61N1/0514 , A61N1/0526 , A61N1/0529 , A61N1/0548 , A61N1/0551 , A61N1/0553 , A61N1/36 , A61N1/36003 , A61N1/3601 , A61N1/3605 , A61N1/36057 , A61N1/3606 , A61N1/3611 , A61N1/36117 , A61N1/36125 , A61N1/36135 , A61N1/36139 , A61N1/36146 , A61N1/37211 , A61N1/37223 , A61N1/37229 , A61N1/37235 , A61N1/37264 , A61N1/3727 , A61N1/3756 , A61N1/3787 , A61N2/006 , A61N2/02 , F04C2270/0421
摘要： A device according to some embodiments may include a housing configured for location external to a body of a subject. The device may also include at least one processor associated with the housing and configured for electrical communication with a power source, and an antenna associated with the at least one processor. The at least one processor may be configured to communicate with an implant circuit located within the body of the subject, cause the implant circuit to receive power in a first power mode and in a second power mode, wherein a first level of power delivered in the first power mode is less than a second level of power delivered in the second power mode, and wherein during a therapy period, power delivery in the first mode occurs over a total time that is greater than about 50% of the therapy period.
摘要翻译：根据一些实施例的装置可以包括构造成用于位于对象的身体外部的位置的壳体。该设备还可以包括与壳体相关联并被配置用于与电源的电通信的至少一个处理器以及与该至少一个处理器相关联的天线。所述至少一个处理器可以被配置为与位于所述对象体内的注入电路进行通信，使得所述注入电路以第一功率模式和第二功率模式接收功率，其中在所述第一功率模式第一功率模式小于在第二功率模式下递送的功率的第二水平，并且其中在治疗周期期间，在大于治疗周期的约50％的总时间内发生第一模式中的功率输送。

64. 发明申请

WO2013046039A2 APPARATUS AND METHOD FOR DETECTING A SLEEP DISORDERED BREATHING PRECURSOR 审中-公开
标题翻译：用于检测睡眠障碍性呼吸前体的装置和方法
公开(公告)号：WO2013046039A2
公开(公告)日：2013-04-04
申请号：PCT/IB2012/002372
申请日：2012-09-28
申请人： MASHIACH, Adi
发明人： MASHIACH, Adi
IPC分类号： A61N1/05
CPC分类号： A61N1/36075 , A61B5/0031 , A61B5/11 , A61B5/113 , A61B5/4519 , A61B5/4818 , A61B5/682 , A61B5/6822 , A61B5/6833 , A61B5/6876 , A61B2562/164 , A61F5/566 , A61N1/05 , A61N1/0504 , A61N1/0514 , A61N1/0526 , A61N1/0529 , A61N1/0548 , A61N1/0551 , A61N1/0553 , A61N1/36 , A61N1/36003 , A61N1/3601 , A61N1/3605 , A61N1/36057 , A61N1/3606 , A61N1/3611 , A61N1/36117 , A61N1/36125 , A61N1/36135 , A61N1/36139 , A61N1/36146 , A61N1/37211 , A61N1/37223 , A61N1/37229 , A61N1/37235 , A61N1/37264 , A61N1/3727 , A61N1/3756 , A61N1/3787 , A61N2/006 , A61N2/02 , F04C2270/0421
摘要： A device according to some embodiments may include a primary antenna configured to be located external to a subject. The device may also include at least one processor in electrical communication with the primary antenna and configured to receive a condition signal from an implantable device, the condition signal indicative of a precursor to sleep disordered breathing, and cause transmission of a primary signal from the primary antenna to the implantable device, in response to the condition signal, to stimulate at least one nerve in response to the precursor to sleep disordered breathing.
摘要翻译：根据一些实施例的设备可以包括被配置为位于被摄体外部的主天线。该装置还可以包括与主天线电通信的至少一个处理器，并被配置为从可植入装置接收条件信号，所述状态信号指示睡眠呼吸的无序的前兆，并且使主信号从初级天线到可植入装置，响应于条件信号，以响应于前体而刺激至少一个神经以睡眠呼吸紊乱。

65. 发明申请

WO2013018083A2 ELECTROSTIMULATION IN TREATING CEREBROVASCULAR CONDITIONS 审中-公开
标题翻译：电解治疗脑血管病变
公开(公告)号：WO2013018083A2
公开(公告)日：2013-02-07
申请号：PCT/IL2012/000290
申请日：2012-08-02
申请人： SAMSON NEUROSCIENCES LTD , SHALEV, Alon , LEVY, Ronnie , BEINART, Yiftach
发明人： SHALEV, Alon , LEVY, Ronnie , BEINART, Yiftach
CPC分类号： A61N1/36103 , A61N1/0558 , A61N1/36017 , A61N1/36025 , A61N1/36053 , A61N1/36057 , A61N1/36175 , A61N1/3787
摘要： A system for treating a medical condition in a living body, comprising two subsystems, an implant subsystem and an electrical stimulation unit subsystem. The implant subsystem comprises at least one electrostimulation module, contains at least one electrically conductive electrode and, preferably, an anchoring member. The electrical stimulation unit, adapted for producing and controlling electrical waveforms, is connected to the electrodes. The implant subsystem is implanted adjacent to at least one of the following structures: the carotid sinus nerve, aortic nerve, common carotid artery, external carotid artery, internal carotid artery, carotid artery bifurcation, carotid body, aortic body or aortic arch receptors. The electrical stimulation unit is maintained outside the patient's body and is adapted to program, generate, control and deliver the electrical waveform via a wired or a wireless connection to the implant subsystem, thereby stimulating the structure it is adjacent to and treating the medical condition.
摘要翻译：一种用于治疗生物体内的医疗状况的系统，包括两个子系统，植入子系统和电刺激单元子系统。植入子系统包括至少一个电刺激模块，其包含至少一个导电电极，并且优选地包括锚定构件。适于产生和控制电波形的电刺激单元连接到电极。植入子系统相邻于以下结构中的至少一个：颈动脉窦神经，主动脉神经，颈总动脉，颈外动脉，颈内动脉，颈动脉分叉，颈动脉体，主动脉体或主动脉弓受体。电刺激单元保持在患者身体外部，并且适于通过有线或无线连接程序，生成，控制和传送电波形到植入物子系统，从而刺激与邻近并治疗医疗状况的结构。

66. 发明申请

WO2012154800A1 TRANSVENOUS RENAL NERVE MODULATION FOR TREATMENT OF HYPERTENSION, CARDIOVASCULAR DISORDERS, AND CHRONIC RENAL DISEASES 审中-公开
标题翻译：用于治疗高血压，心血管疾病和慢性肾衰竭的转移性神经调节
公开(公告)号：WO2012154800A1
公开(公告)日：2012-11-15
申请号：PCT/US2012/037042
申请日：2012-05-09
申请人： ST. JUDE MEDICAL, INC. , ZHANG, Yongxing , HATA, Cary
发明人： ZHANG, Yongxing , HATA, Cary
IPC分类号： A61N1/00 , A61N1/39
CPC分类号： A61N1/36139 , A61N1/36057 , A61N1/36117 , A61N1/3627 , A61N1/36564
摘要： A transvenous renal nerve modulation system comprises: a blood pressure monitoring device (106) to be implanted in a patient to monitor the patient's blood pressure; one or more transvenous renal nerve modulation leads (110) to be implanted in one or more renal blood vessels of the patient; a pulse generator (102) coupled to the transvenous renal nerve modulation leads to deliver electrical pulses to the one or more transvenous renal nerve modulation leads for modulating renal nerves of the patient; and a control unit (104) coupled to the blood pressure monitoring device and the pulse generator to control delivery of the electrical pulses by the pulse generator based on the patient's blood pressure from the blood pressure monitoring device. The pulse generator delivers high frequency pulses of greater than about 10 Hz to the transvenous renal nerve modulation leads if the patient's blood pressure is greater than a high blood pressure threshold.
摘要翻译：经静脉肾神经调节系统包括：待植入患者的血压监测装置（106）以监测患者的血压; 一个或多个经静脉肾神经调节引线（110）被植入患者的一个或多个肾血管中; 耦合到经静脉肾神经调节的脉冲发生器（102）导致将电脉冲传递到一个或多个经静脉肾神经调节引线，用于调节患者的肾神经; 以及耦合到所述血压监测装置和所述脉冲发生器的控制单元（104），其基于来自所述血压监测装置的患者的血压来控制所述脉冲发生器的电脉冲的输送。如果患者的血压高于高血压阈值，则脉冲发生器将高于约10Hz的高频脉冲传递给经静脉肾神经调制线。

67. 发明申请

WO2009134350A2 SYSTEMS FOR SELECTIVELY STIMULATING NERVE ROOTS 审中-公开
标题翻译：选择神经刺激的系统
公开(公告)号：WO2009134350A2
公开(公告)日：2009-11-05
申请号：PCT/US2009002575
申请日：2009-04-28
申请人： CARDIAC PACEMAKERS INC , ZHAO WEIYING , RUBLE STEPHEN , SHUROS ALLAN C , HAMANN JASON J
发明人： ZHAO WEIYING , RUBLE STEPHEN , SHUROS ALLAN C , HAMANN JASON J
IPC分类号： A61N1/36
CPC分类号： A61N1/36117 , A61N1/0551 , A61N1/0553 , A61N1/0556 , A61N1/36057 , A61N1/36071 , A61N1/36114 , A61N1/36139 , A61N1/3627 , A61N1/365 , A61N1/37241
摘要： Various system embodiments comprise an implantable lead, an implantable housing, a neural stimulation circuit in the housing, and a controller in the housing and connected to the neural stimulation circuit. The lead has a proximal end and a distal end. The distal end is adapted to deliver neural stimulation pulses to the ventral nerve root and the dorsal nerve root. The proximal end of the lead is adapted to connect to the housing. The neural stimulation circuit is adapted to generate neural stimulation pulses to stimulate the ventral nerve root or the dorsal nerve root using the implantable lead. The controller is adapted to control the neural stimulation circuit to deliver a neural stimulation treatment. systems for selectively stimulating nerve roots
摘要翻译：各种系统实施例包括可植入引线，可植入壳体，壳体中的神经刺激电路以及壳体中的控制器并连接到神经刺激电路。引线具有近端和远端。远端适于将神经刺激脉冲输送到腹侧神经根和背神经根。引线的近端适于连接到外壳。神经刺激电路适于产生神经刺激脉冲，以使用可植入引线刺激腹侧神经根或背神经根。控制器适于控制神经刺激电路以递送神经刺激治疗。用于选择性刺激神经根的系统

68. 发明申请

WO2008123923A2 UNIDIRECTIONAL NEURAL STIMULATION SYSTEMS, DEVICES AND METHODS 审中-公开
标题翻译：单向神经刺激系统，装置和方法
公开(公告)号：WO2008123923A2
公开(公告)日：2008-10-16
申请号：PCT/US2008/003683
申请日：2008-03-20
申请人： CARDIAC PACEMAKERS, INC. , LIBBUS, Imad , SCHEINER, Avram
发明人： LIBBUS, Imad , SCHEINER, Avram
IPC分类号： A61N1/36
CPC分类号： A61N1/36057 , A61B5/021 , A61B5/024 , A61N1/0551 , A61N1/36114 , A61N1/36135 , A61N1/37217 , A61N1/37282 , A61N1/37288
摘要： An embodiment relates to a method for delivering a unidirectional afferent nerve stimulation treatment. A test neural stimulation is delivered, and a physiologic response to the test neural stimulation is monitored. At least one neural stimulation parameter for the test neural stimulation is adjusted if the test neural stimulation does not elicit a desired physiologic response. If the test neural stimulation does elicit the desired physiologic response, at least one treatment parameter for a unidirectional afferent nerve stimulation is determined using the at least one neural stimulation parameter for the test neural stimulation that provided the desired physiologic response. The unidirectional afferent nerve stimulation is delivered using the at least one treatment parameter.
摘要翻译：一个实施例涉及一种用于递送单向传入神经刺激治疗的方法。递送测试神经刺激，并监测对测试神经刺激的生理反应。如果测试神经刺激不引起期望的生理反应，则调整用于测试神经刺激的至少一个神经刺激参数。如果测试神经刺激引起期望的生理反应，则使用提供所需生理反应的测试神经刺激的至少一个神经刺激参数来确定单向传入神经刺激的至少一个治疗参数。使用至少一个治疗参数传递单向传入神经刺激。

69. 发明申请

WO2008066585A2 FLEXIBLE COMMUNICATION AND CONTROL PROTOCOL FOR A WIRELESS SENSOR AND MICROSTIMULATOR NETWORK 审中-公开
标题翻译：无线传感器和微型计算机网络的灵活通信和控制协议
公开(公告)号：WO2008066585A2
公开(公告)日：2008-06-05
申请号：PCT/US2007/015484
申请日：2007-07-05
申请人： UNIVERSITY OF SOUTHERN CALIFORNIA USC STEVENS , LOEB, Gerald, E. , WEISSBERG, Jack , RODRIGUEZ, Nuria
发明人： LOEB, Gerald, E. , WEISSBERG, Jack , RODRIGUEZ, Nuria
IPC分类号： A61N1/08 , A61N1/05
CPC分类号： A61N1/37288 , A61N1/36003 , A61N1/36057 , A61N1/36139 , A61N1/37205
摘要： A novel system and method for restoring functional movement of a paralyzed limb(s) or a prosthetic device. Stimulating one or more muscles of a patient using an implanted neuromuscular implants and sensing the response of the stimulated muscle by the implants, wherein the sensing the response is not limited to data related to patient's movement intention, the posture, muscle extension, M-Wave and EMG. A communication and control protocol to operate the system safely and efficiently, use of forward and reverse telemetry channels having a limited bandwidth capacity, and minimizing the adverse consequences caused by errors in data transmission and intermittent loss of power to the implants. Adjusting stimulation rates and phases of the stimulator in order to achieve an efficient control of muscle force while minimizing fatigue and therefore providing for smooth movements and dynamic increase of the strength in patient's muscle contraction.
摘要翻译：一种用于恢复瘫痪肢体或假体装置的功能运动的新型系统和方法。使用植入的神经肌肉植入物刺激患者的一个或多个肌肉并感测植入物对受刺激肌肉的反应，其中感测反应不限于与患者的运动意图，姿势，肌肉伸展，M波和EMG。一种用于安全有效地操作系统的通信和控制协议，使用具有有限带宽容量的正向和反向遥测通道，并且最小化由于数据传输中的错误和对植入物的间歇性功率损耗而引起的不良后果。调整刺激器的刺激速率和阶段，以便实现肌肉力量的有效控制，同时最大限度地减少疲劳，从而提供平稳运动和动态增加患者肌肉收缩的强度。

70. 发明申请

WO2005040989A2 TACTILE INPUT SYSTEM 审中-公开
标题翻译：战术输入系统
公开(公告)号：WO2005040989A2
公开(公告)日：2005-05-06
申请号：PCT/US2004/035305
申请日：2004-10-22
申请人： BACH-Y-RITA, Paul , FISHER, Edward, N.
发明人： BACH-Y-RITA, Paul , FISHER, Edward, N.
IPC分类号： G06F
CPC分类号： H04R27/00 , A61N1/36017 , A61N1/36057 , A61N1/37205 , A61N1/3787 , G09B21/003 , H04R5/02
摘要： The present invention relates to systems and methods for management of brain and body functions and sensory perception. For example, the present invention provides systems and methods of sensory substitution and sensory enhancement (augmentation) using tactile stimulators implanted under the skin.
摘要翻译：本发明涉及用于管理脑和身体功能和感觉知觉的系统和方法。例如，本发明提供使用植入皮下的触觉刺激器的感官替代和感觉增强（增强）的系统和方法。

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