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    • 1. 发明申请
    • STENT-GRAFTS WITH POST-DEPLOYMENT VARIABLE AXIAL AND RADIAL DISPLACEMENT
    • 具有后置部分可变轴向和径向位移的STENT-GRAFTS
    • WO2013030818A3
    • 2015-06-18
    • PCT/IL2012000148
    • 2012-04-04
    • ENDOSPAN LTDSHALEV ALON
    • SHALEV ALON
    • A61F2/82
    • A61F2/07A61F2/82A61F2/89A61F2002/065A61F2002/075A61F2210/0057A61F2210/0066A61F2220/0075A61F2230/0078A61F2250/0007A61F2250/001A61F2250/0013A61F2250/0039
    • An endovascular stent-graft (20) includes a generally tubular body (22), which is configured to assume a radially-compressed delivery state and a radially-expanded deployment state. The body (22) includes a flexible stent member (24), and a tubular fluid flow guide (26) attached to the stent member (24). The body (22) includes a compliance-restoration body portion (34), which extends axially along a portion of the body, and which comprises a portion of the stent member (24) and a portion of the fluid flow guide (26). When the body (22) is in the radially-expanded deployment state, the compliance-restoration body portion (34) is (a) characterized by a greatest diastolic outer radius (RD) when the body (22) is internally pressurized by fluid having a pressure of 80 mmHg, and (b) radially expandable to a greatest systolic outer radius (RS) when the body (22) is internally pressurized by fluid having a pressure of 120 mmHg. The greatest systolic outer radius (RS) is at least 5% greater than the greatest diastolic outer radius (RD).
    • 血管内支架移植物(20)包括大致管状体(22),其构造为呈现径向压缩的递送状态和径向扩张的展开状态。 主体(22)包括柔性支架构件(24)和连接到支架构件(24)的管状流体流动引导件(26)。 主体(22)包括顺应性恢复主体部分(34),其沿主体的一部分轴向延伸,并且包括支架构件(24)的一部分和流体流动引导件(26)的一部分。 当身体(22)处于径向展开的展开状态时,柔顺修复体部分(34)的特征在于当身体(22)被内部加压时具有最大的舒张外半径(RD) 80mmHg的压力,以及(b)当身体(22)由压力为120mmHg的流体内部加压时,径向可扩张至最大的收缩外半径(RS)。 最大的收缩期外半径(RS)比最大舒张外半径(RD)至少大5%。
    • 2. 发明申请
    • STENT-GRAFTS WITH POST-DEPLOYMENT VARIABLE AXIAL AND RADIAL DISPLACEMENT
    • 具有后置部分可变轴向和径向位移的STENT-GRAFTS
    • WO2013030818A2
    • 2013-03-07
    • PCT/IL2012/000148
    • 2012-04-04
    • ENDOSPAN LTD.SHALEV, Alon
    • SHALEV, Alon
    • A61F2/94
    • A61F2/07A61F2/82A61F2/89A61F2002/065A61F2002/075A61F2210/0057A61F2210/0066A61F2220/0075A61F2230/0078A61F2250/0007A61F2250/001A61F2250/0013A61F2250/0039
    • An endovascular stent-graft (20) includes a generally tubular body (22), which is configured to assume a radially-compressed delivery state and a radially-expanded deployment state. The body (22) includes a flexible stent member (24), and a tubular fluid flow guide (26) attached to the stent member (24). The body (22) includes a compliance-restoration body portion (34), which extends axially along a portion of the body, and which comprises a portion of the stent member (24) and a portion of the fluid flow guide (26). When the body (22) is in the radially-expanded deployment state, the compliance-restoration body portion (34) is (a) characterized by a greatest diastolic outer radius (R D ) when the body (22) is internally pressurized by fluid having a pressure of 80 mmHg, and (b) radially expandable to a greatest systolic outer radius (R S ) when the body (22) is internally pressurized by fluid having a pressure of 120 mmHg. The greatest systolic outer radius (R S ) is at least 5% greater than the greatest diastolic outer radius (R D ).
    • 血管内支架移植物(20)包括大致管状体(22),其构造为呈现径向压缩的递送状态和径向扩张的展开状态。 主体(22)包括柔性支架构件(24)和连接到支架构件(24)的管状流体流动引导件(26)。 主体(22)包括顺应性恢复主体部分(34),其沿主体的一部分轴向延伸,并且包括支架构件(24)的一部分和流体流动引导件(26)的一部分。 当身体(22)处于径向展开的展开状态时,柔顺修复体部分(34)的特征在于当身体(22)被内部加压时具有最大的舒张外半径(RD) 80mmHg的压力,以及(b)当身体(22)由压力为120mmHg的流体内部加压时,径向可扩张至最大的收缩外半径(RS)。 最大的收缩期外半径(RS)比最大舒张外半径(RD)至少大5%。
    • 4. 发明申请
    • VASCULAR PROSTHESES FOR TREATING ANEURYSMS
    • WO2010150208A3
    • 2010-12-29
    • PCT/IB2010/052861
    • 2010-06-23
    • ENDOSPAN LTD.SHALEV, AlonBENARY, Rafi
    • SHALEV, AlonBENARY, Rafi
    • A61F2/06
    • An endovascular stent-graft (5) is configured to initially be positioned in a delivery catheter (30) in a radially-compressed state, and to assume a radially-expanded state upon being deployed from the delivery catheter (30). The stent-graft (5) includes a structural member (10), including a plurality of structural stent elements (15), at least a portion of which structural stent elements (15) define a stent body (8) when the stent-graft (5) assumes the radially-expanded state. The stent-graft (5) further includes a fluid flow guide (16), including at least one biologically-compatible substantially fluid-impervious flexible sheet, and coupled to the stent body (8). When the stent-graft (5) assumes the radially-expanded state, the fluid flow guide (16) is shaped so as to define radially- diverging and radially-converging portions (13, 19), which together define a bulge (20) that extends radially outward, and has a greatest cross-sectional area that is equal to at least 120% of a cross-sectional area of a narrowest portion (17) of the stent-graft (5) rostral to the bulge (20). Other embodiments are also described.
    • 5. 发明申请
    • APPARATUS AND METHOD FOR CREATING ARTERIOVENOUS FISTULAS
    • 用于创建异常成纤维细胞的装置和方法
    • WO2009107142A3
    • 2010-03-11
    • PCT/IL2009000232
    • 2009-03-01
    • FISTULINK LTDSHALEV ALONLEV TIFFANY
    • SHALEV ALONLEV TIFFANY
    • A61F2/06
    • A61F2/07A61F2/90A61F2002/061
    • Apparatus (20) is provided for creating a connection between a first body lumen (114) of a subject and a second body lumen (116) of the subject. The apparatus (20) includes a first engagement portion (102) configured to engage a wall of a first body lumen (114), a second engagement portion (104) that engages a wall of a second body lumen (116), and a cylindrical connecting portion (106) connecting the first engagement portion (102) to the second engagement portion (104). The connecting portion (106) defines a channel therethrough for passage of fluid from the inner space of the lumen (114), through the flow channel, and into the inner space of the body lumen (116). The apparatus also includes a projection (200) coupled to the second engagement portion (104), and surrounds an external surface of the wall of the lumen (116). Other embodiments are also described.
    • 设备(20)用于在受试者的第一体腔(114)和对象的第二体腔(116)之间建立连接。 装置(20)包括构造成与第一体腔(114)的壁接合的第一接合部分(102),与第二体腔(116)的壁接合的第二接合部分(104) 连接部分(106)将第一接合部分(102)连接到第二接合部分(104)。 连接部分(106)限定穿过其中的通道,用于使流体从内腔(114)的内部空间通过流动通道并进入体腔(116)的内部空间。 该装置还包括联接到第二接合部分(104)并且围绕管腔(116)的壁的外表面的突起(200)。 还描述了其它实施例。
    • 6. 发明申请
    • EXTRA-VASCULAR WRAPPING FOR TREATING ANEURYSMATIC AORTA IN CONJUNCTION WITH ENDOVASCULAR STENT-GRAFT AND METHODS THEREOF
    • 用于治疗与内膜支架连接的神经外科的额外的包裹体及其方法
    • WO2009078010A3
    • 2010-03-11
    • PCT/IL2008001621
    • 2008-12-15
    • ANEUWRAP LTDSHALEV ALON
    • SHALEV ALON
    • A61F2/06
    • A61F2/06A61B17/12A61B17/12113A61B17/12168A61F2/07A61F2220/0008
    • A system for treating an aneurysmatic abdominal aorta, comprising (a) an extra-vascular wrapping (EVW) comprising (i) at least one medical textile member adapted to at least partially encircle a segment of aorta in proximity to the renal arteries, and (ii) a structural member, wherein EVW is adapted for laparoscopic delivery, and (b) an endovascular stent-graft (ESG) comprising (i) a compressible structural member, and (ii) a substantially fluid impervious fluid flow guide (FFG) attached thereto. Also described is an extra-vascular ring (EVR) adapted to encircle the neck of an aortic aneurysm. Further described are methods for treating an abdominal aortic aneurysm, comprising laparoscopically delivering the extra-vascular wrapping (EVW) and endovascularly placing an endovascular stent-graft (ESG). Also described are methods to treat a type I endoleak.
    • 一种用于治疗动脉瘤性腹主动脉的系统,包括(a)血管外包裹物(EVW),其包括(i)适于至少部分地围绕肾动脉附近的主动脉段的至少一种医用织物构件,和 ii)结构构件,其中EVW适于腹腔镜递送,和(b)包括(i)可压缩结构构件的血管内支架移植物(ESG),和(ii)附接的基本上不透液体的流体流动引导件(FFG) 于此。 还描述了适于环绕主动脉瘤颈部的超血管环(EVR)。 还描述了用于治疗腹主动脉瘤的方法,包括腹腔镜下输送血管外包裹(EVW)和血管内置入血管内支架移植物(ESG)。 还描述了治疗I型内漏的方法。
    • 7. 发明申请
    • APPARATUS AND METHOD FOR CREATING ARTERIOVENOUS FISTULAS
    • 用于创建异常成纤维细胞的装置和方法
    • WO2009107142A2
    • 2009-09-03
    • PCT/IL2009/000232
    • 2009-03-01
    • FISTULINK LTD.SHALEV, AlonLEV, Tiffany
    • SHALEV, AlonLEV, Tiffany
    • G08B13/24
    • A61F2/07A61F2/90A61F2002/061
    • Apparatus (20) is provided for creating a connection between a first body lumen (114) of a subject and a second body lumen (116) of the subject. The apparatus (20) includes a first engagement portion (102) configured to engage a wall of a first body lumen (114), a second engagement portion (104) that engages a wall of a second body lumen (116), and a cylindrical connecting portion (106) connecting the first engagement portion (102) to the second engagement portion (104). The connecting portion (106) defines a channel therethrough for passage of fluid from the inner space of the lumen (114), through the flow channel, and into the inner space of the body lumen (116). The apparatus also includes a projection (200) coupled to the second engagement portion (104), and surrounds an external surface of the wall of the lumen (116). Other embodiments are also described.
    • 设备(20)用于在受试者的第一体腔(114)和对象的第二体腔(116)之间建立连接。 装置(20)包括构造成与第一体腔(114)的壁接合的第一接合部分(102),与第二体腔(116)的壁接合的第二接合部分(104) 连接部分(106)将第一接合部分(102)连接到第二接合部分(104)。 连接部分(106)限定穿过其中的通道,用于使流体从内腔(114)的内部空间通过流动通道并进入体腔(116)的内部空间。 该装置还包括联接到第二接合部分(104)并且围绕管腔(116)的壁的外表面的突起(200)。 还描述了其它实施例。