专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

11. 发明申请

WO2006014460A2 SPOTTING DEVICE AND METHOD FOR HIGH CONCENTRATION SPOT DEPOSITION ON MICROARRAYS AND OTHER MICROSCALE DEVICES 审中-公开
标题翻译：微型装置和其他微型装置的高浓度点沉积物的分选装置和方法
公开(公告)号：WO2006014460A2
公开(公告)日：2006-02-09
申请号：PCT/US2005/023895
申请日：2005-07-06
申请人： UNIVERSITY OF UTAH RESEARCH FOUNDATION , GALE, Bruce , CHANG-YEN, David , MYSZKA, David
发明人： GALE, Bruce , CHANG-YEN, David , MYSZKA, David
CPC分类号： B01J19/0046 , B01J2219/00353 , B01J2219/00367 , B01J2219/00369 , B01J2219/00371 , B01J2219/00497 , B01J2219/00527 , B01J2219/00536 , B01J2219/00574 , B01J2219/00576 , B01J2219/00585 , B01J2219/00596 , B01J2219/00605 , B01J2219/0061 , B01J2219/00612 , B01J2219/00619 , B01J2219/00621 , B01J2219/00626 , B01J2219/00628 , B01J2219/0063 , B01J2219/00637 , B01J2219/00639 , B01J2219/00644 , B01J2219/00648 , B01J2219/00659 , B01J2219/00675 , B01J2219/00677 , B01J2219/00691 , B01J2219/00693 , B01J2219/00722 , B01J2219/00725 , B01J2219/00731 , B01J2219/00734 , B01J2219/00736 , B01J2219/00743 , B01L3/0293 , B01L3/5027 , B01L3/502707 , B01L3/502715 , B01L3/50273 , B01L3/502761 , B01L2200/0647 , B01L2200/147 , B01L2300/0636 , B01L2300/0654 , B01L2300/0822 , B01L2300/0877 , B01L2300/1827 , B01L2400/0415 , B01L2400/0487 , B82Y30/00 , C12M23/16 , C40B50/14 , C40B60/14 , G01N35/1002 , G01N35/1065 , G01N35/1074 , G01N2035/00158 , G01N2035/1034 , G01N2035/1039 , Y10T29/49
摘要： Disclosed is a spotter device and methods for the formation of microassays, biochips, biosensors, and cell cultures. The spotter may be used to deposit highly concentrated spots of protein or other materials on a microarray slide, wafer, or other substrate. It may also be used to perform various chemistry steps on the same spots. The spotter increases the surface density of substances at each spot by directing a flow of solution bearing the desired substance over the spot area until surface saturation is accomplished. The spotter uses microfluidic conduits and orifices to deposit proteins, other biomolecules, or chemicals on a spot on a separate substrate. Each orifice is part of a fluid pathways that includes an inlet conduit and an outlet conduit. When the spotter contacts a substrate a seal is formed between the orifices and the substrate. The same or different substances may be flowed across each orifice. Any number of orifices may be incorporated into a spotter. The spotter is particularly useful for depositing proteins in high concentrations on a substrate, since the spotter may be placed on a substrate for an extended period of time.
摘要翻译：公开了一种用于形成微量测定器，生物芯片，生物传感器和细胞培养物的检测器装置和方法。斑点斑块可用于将高度浓缩的蛋白质或其他材料的斑点沉积在微阵列载玻片，晶片或其它基底上。它也可以用于在同一点上执行各种化学步骤。点样器通过将含有所需物质的溶液流引导到斑点区域，直到达到表面饱和为止，增加每个斑点处物质的表面密度。点样器使用微流体导管和孔口在单独的基底上的斑点上沉积蛋白质，其他生物分子或化学物质。每个孔是包括入口导管和出口导管的流体路径的一部分。当检测器接触基板时，在孔和基板之间形成密封。相同或不同的物质可能流过每个孔口。任何数量的孔口都可以并入到一个定点器中。斑点剂对于在基质上沉积高浓度的蛋白质是特别有用的，因为可以将斑点剂放置在衬底上较长时间。

12. 发明申请

WO2004065009A1 PROBENGEFÄSS FÜR ANALYSEN 审中-公开
标题翻译：样品容器进行分析
公开(公告)号：WO2004065009A1
公开(公告)日：2004-08-05
申请号：PCT/EP2004/000311
申请日：2004-01-16
申请人： GREINER BIO-ONE GMBH , KNEBEL, Günther , STAPPERT, Jörg , JEHLE, Heinrich , KESSLER, Joachim
发明人： KNEBEL, Günther , STAPPERT, Jörg , JEHLE, Heinrich , KESSLER, Joachim
IPC分类号： B01L3/00
CPC分类号： B82Y30/00 , B01J2219/00315 , B01J2219/00511 , B01J2219/00574 , B01J2219/00576 , B01J2219/00587 , B01J2219/00596 , B01J2219/00677 , B01J2219/00722 , B01J2219/00725 , B01J2219/00729 , B01L3/50855 , B01L2300/0636 , B01L2300/0829 , B01L2300/0851 , C40B40/06 , C40B40/10 , C40B60/14 , G01N33/54353
摘要： Die vorliegende Erfindung betrifft ein zur medizinischen Diagnostik geeignetes Probengefäss für Analysen, umfassend eine Trägerplatte mit mindestens einer Reaktionskammer.
摘要翻译：本发明涉及适用于医学诊断，用于分析样品的容器，包括具有至少一个反应室中的载体板的系统。

13. 发明申请

WO2004013607A3 METHODS, DEVICES AND KITS FOR MULTIPLEX BLOTTING OF BIOLOGICAL SAMPLES FROM MULTI-WELL PLATES 审中-公开
标题翻译：多孔玻璃生物样品的多重蒸煮方法，装置和工具
公开(公告)号：WO2004013607A3
公开(公告)日：2004-04-08
申请号：PCT/US0324225
申请日：2003-08-01
申请人： 20 20 GENESYSTEMS INC , US GOV HEALTH & HUMAN SERV , KNEZEVIC VLADIMIR , HARTMANN DAN-PAUL , EMMERT-BUCK MICHAEL R
发明人： KNEZEVIC VLADIMIR , HARTMANN DAN-PAUL , EMMERT-BUCK MICHAEL R
IPC分类号： B01J19/00 , B01L3/00 , C12Q1/68 , C40B40/06 , C40B40/10 , G01N33/543 , G01N33/53
CPC分类号： B01L3/50255 , B01J19/0046 , B01J2219/00416 , B01J2219/00533 , B01J2219/00574 , B01J2219/00576 , B01J2219/00605 , B01J2219/0061 , B01J2219/00637 , B01J2219/00641 , B01J2219/00659 , B01J2219/00668 , B01J2219/00677 , B01J2219/00722 , B01J2219/00725 , B01L2300/0627 , B01L2300/0829 , B01L2400/049 , C40B40/06 , C40B40/10 , G01N33/54373
摘要： The present disclosure provides methods, devices and kits that permit large numbers of target biomolecules to be detected simultaneously in samples originating from a multi-sample holder, such as multi-well plate. One specific example method is a method of making multiple substantial replicas of a biomolecular content of a multi-well sample holder. Devices and kits for carrying out the described methods are also provided.
摘要翻译：本公开提供了允许在源自多样品保持器（例如多孔板）的样品中同时检测大量目标生物分子的方法，装置和试剂盒。一个具体的示例方法是制备多孔样品保持器的生物分子含量的多个实质性复制品的方法。还提供了用于执行所述方法的设备和套件。

14. 发明申请

WO2004013607A2 METHODS, DEVICES AND KITS FOR MULTIPLEX BLOTTING OF BIOLOGICAL SAMPLES FROM MULTI-WELL PLATES 审中-公开
标题翻译：用于多孔板生物样品多重喷涂的方法，装置和套件
公开(公告)号：WO2004013607A2
公开(公告)日：2004-02-12
申请号：PCT/US2003/024225
申请日：2003-08-01
申请人： 20/20 GENESYSTEMS, INC. , THE GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES , KNEZEVIC, Vladimir , HARTMANN, Dan-Paul , EMMERT-BUCK, Michael, R.
发明人： KNEZEVIC, Vladimir , HARTMANN, Dan-Paul , EMMERT-BUCK, Michael, R.
IPC分类号： G01N
CPC分类号： B01L3/50255 , B01J19/0046 , B01J2219/00416 , B01J2219/00533 , B01J2219/00574 , B01J2219/00576 , B01J2219/00605 , B01J2219/0061 , B01J2219/00637 , B01J2219/00641 , B01J2219/00659 , B01J2219/00668 , B01J2219/00677 , B01J2219/00722 , B01J2219/00725 , B01L2300/0627 , B01L2300/0829 , B01L2400/049 , C40B40/06 , C40B40/10 , G01N33/54373
摘要： The present disclosure provides methods, devices and kits that permit large numbers of target biomolecules to be detected simultaneously in samples originating from a multi-sample holder, such as multi-well plate. One specific example method is a method of making multiple substantial replicas of a biomolecular content of a multi-well sample holder. Devices and kits for carrying out the described methods are also provided.
摘要翻译：本公开提供了允许在源自多样品保持器（例如多孔板）的样品中同时检测大量目标生物分子的方法，装置和试剂盒。一个具体示例性方法是制造多孔样品架的生物分子含量的多个实质复制品的方法。还提供了执行所述方法的设备和套件。

15. 发明申请

WO2004008142A1 分析用チップ、分析用チップユニット、分析装置及びそれを用いた分析方法並びに分析用チップの作製方法审中-公开
标题翻译：分析芯片，分析芯片单元，分析装置，使用装置的分析方法和生产分析芯片的方法
公开(公告)号：WO2004008142A1
公开(公告)日：2004-01-22
申请号：PCT/JP2003/008851
申请日：2003-07-11
申请人：三菱化学株式会社 , 高山英士
发明人：高山英士
IPC分类号： G01N33/53
CPC分类号： G01N33/54366 , B01F5/0646 , B01F5/0655 , B01F13/0059 , B01J2219/00497 , B01J2219/00549 , B01J2219/00574 , B01J2219/00576 , B01J2219/00585 , B01J2219/00596 , B01J2219/00605 , B01J2219/00612 , B01J2219/00637 , B01J2219/00641 , B01J2219/00659 , B01J2219/00707 , B01J2219/00722 , B01J2219/00725 , B01L3/502707 , B01L3/502723 , B01L3/502746 , B01L2300/0636 , B01L2300/0825 , B01L2300/0864 , B01L2300/0867 , B01L2300/0877 , B01L2300/0887 , B01L2400/086 , B82Y30/00 , B82Y35/00 , C40B40/06 , C40B40/10 , G01N30/0005 , G01N30/6043 , G01N30/6065 , G01N30/466 , G01N30/461
摘要：閉断面構造を有する流路（５）に液体検体（Ｆｓ）を流通させて、所定物質と、流路（５）に面して固定される特定物質（６１）との相互作用に基づいて液体検体（Ｆｓ）に関する分析を行なうのに使用される、分析用チップであって、その流路（５）に、凸状部材（９ｂ）を有する。これにより、液体検体（Ｆｓ）を効率的に且つ精度良く分析することができる。
摘要翻译：用于分析液体样品（Fs）的分析芯片。液体样品（Fs）在具有闭合截面结构的流动通道（5）中循环，并且基于预定材料和面向流动通道（5）的固定物质（61）之间的相互作用进行分析，。流动通道（5）具有凸形构件（9b）。可以有效且准确地分析液体样品（Fs）。

16. 发明申请

WO2003030129A2 LABELLED ARTICLES AND USES THEREOF 审中-公开
标题翻译：标签文章及其用途
公开(公告)号：WO2003030129A2
公开(公告)日：2003-04-10
申请号：PCT/EP2002/010816
申请日：2002-09-26
申请人： UCB, S.A. , REGAN, Christopher , WANING, Richard
发明人： REGAN, Christopher , WANING, Richard
IPC分类号： G09F
CPC分类号： G07D7/14 , B01J2219/00378 , B01J2219/00497 , B01J2219/005 , B01J2219/00572 , B01J2219/00574 , B01J2219/00576 , B01J2219/00648 , B01J2219/00722 , B01J2219/00725 , B42D25/29 , C12Q1/6813 , G07F7/08 , G07F7/086 , G07F7/12 , C12Q2563/185
摘要： There is described a process for labeling an article and/or document for authentication purposes. The article or document (such as BOPP and/or cellulose film) incorporates therein particles having a taggant bound to the surface thereof. The preferred taggant is a DNA strand of at least eight (preferably 25) base pairs long attached to inorganic particles by the addition reaction between an acrylate group and a polar group such as amino or hydroxy. Alternatively silica particles can be modified by reacting first with aminopropyltriethoxy silane and then a reagent selected from: a diacid with a polyethylene glycol spacer group (e.g. polyethylene glycol dicarboxymethyl) succinic anhydride; and/or a diisothiocyanate (e.g. 1,4-phenylene diisothiocyanate (PDITC)) to form functional silica particles capable of reacting directly with a terminal amide and/or hydroxy group of an oligonucleotide such as DNA. The tagged particles can be detected by use of a fluorescent probe which hybridises with the DNA sequence selected tag the article or document.
摘要翻译：描述了用于为了认证目的而标记物品和/或文档的过程。物品或文件（例如BOPP和/或纤维素膜）在其中掺入具有与其表面结合的标签的颗粒。优选的标记物是通过丙烯酸酯基和极性基团如氨基或羟基之间的加成反应长期连接到无机颗粒上的至少八个（优选25个）碱基对的DNA链。或者，二氧化硅颗粒可以首先与氨基丙基三乙氧基硅烷反应，然后与选自以下的试剂进行改性：二元酸与聚乙二醇间隔基（例如聚乙二醇二羧甲基）琥珀酸酐; 和/或二异硫氰酸酯（例如1,4-亚苯基二异硫氰酸酯（PDITC）），以形成能够直接与寡核苷酸例如DNA的末端酰胺和/或羟基反应的官能二氧化硅颗粒。可以通过使用荧光探针检测标记的颗粒，所述荧光探针与选择的DNA序列杂交标记物品或文件。

17. 发明申请

WO2003014736A1 BIOLOGICAL MOLECULES COMPRISING GLYCOSAMINOGLYCANS 审中-公开
标题翻译：包含谷氨酰胺聚糖的生物分子
公开(公告)号：WO2003014736A1
公开(公告)日：2003-02-20
申请号：PCT/AU2002/001069
申请日：2002-08-09
申请人： MEDITECH RESERACH LIMITED , KETT, Warren, Charles , COOMBE, Deirdre, Roma , SANDERSON, Colin, John
发明人： KETT, Warren, Charles , COOMBE, Deirdre, Roma , SANDERSON, Colin, John
IPC分类号： G01N33/53
CPC分类号： G01N33/54353 , B01J20/3204 , B01J20/321 , B01J20/3212 , B01J20/3219 , B01J20/3274 , B01J2219/00315 , B01J2219/00497 , B01J2219/005 , B01J2219/0052 , B01J2219/00527 , B01J2219/00536 , B01J2219/00574 , B01J2219/00576 , B01J2219/00605 , B01J2219/0061 , B01J2219/00612 , B01J2219/00621 , B01J2219/00626 , B01J2219/00637 , B01J2219/00659 , B01J2219/00662 , B01J2219/00677 , B01J2219/00731 , G01N33/54326
摘要： The present invention relates generally to a capture device for peptides, polypeptides or proteins or other biological or synthetic molecules, alone in a sample or associated with a cell or virus, cell or virus wall or cell membrane or viral core or an extract or fraction thereof. More particularly, the present invention provides a device useful for facilitating the identification of peptides, polypeptides or proteins or other biological or synthetic molecules alone in a sample or associated with a cell or virus, cell or viral wall, cell membrane or viral core or a portion or fraction thereof immobilized to the device. In a particular embodiment, the present invention comprises a carbohydrate molecule of one or more saccharide monomers associated with a polysaccharide molecule which in turn is immobilized to a solid support useful in the capture of peptides, polypeptides or proteins or other biological or synthetic molecules alone or associated with a cell or virus, cell or viral wall or cell membrane or viral coat or an extract or fraction thereof. The capture device is useful in combination with detection assays such as immune-based detection assays including enzyme-linked immunoassays.
摘要翻译：本发明一般涉及用于肽，多肽或蛋白质或其他生物或合成分子的捕获装置，单独在样品中或与细胞或病毒，细胞或病毒壁或细胞膜或病毒核心或其提取物或分数相关联。更具体地说，本发明提供了一种可用于促进样品中单独或与细胞或病毒，细胞或病毒壁，细胞膜或病毒核心或病毒核心或细胞膜或病毒核心或细胞或细胞膜结合的肽，多肽或蛋白质或其他生物或合成分子的鉴定的装置部分或部分固定在该装置上。在一个具体的实施方案中，本发明包含与多糖分子缔合的一种或多种糖单体的碳水化合物分子，所述多糖分子又被固定在固体支持物上，所述固体支持物可用于单独捕获肽，多肽或蛋白质或其它生物或合成分子，或与细胞或病毒，细胞或病毒壁或细胞膜或病毒外壳或其提取物或部分相关联。捕获装置可与检测分析结合使用，例如基于免疫的检测测定法，包括酶联免疫测定法。

18. 发明申请

WO2002081075A1 DEVICE FOR ARCHIVING AND ANALYZING OF MATERIALS 审中-公开
标题翻译：材料存档和分析设备
公开(公告)号：WO2002081075A1
公开(公告)日：2002-10-17
申请号：PCT/EP2002/003817
申请日：2002-04-05
申请人： HTE AKTIENGESELLSCHAFT , SCHUNK, Stephan, Andreas , KLEIN, Jens , DEMUTH, Dirk , ZECH, Torsten , HÖNICKE, Dieter
发明人： SCHUNK, Stephan, Andreas , KLEIN, Jens , DEMUTH, Dirk , ZECH, Torsten , HÖNICKE, Dieter
IPC分类号： B01J19/00
CPC分类号： B01L3/5025 , B01J19/0046 , B01J2219/00286 , B01J2219/00317 , B01J2219/00319 , B01J2219/00423 , B01J2219/00477 , B01J2219/005 , B01J2219/0054 , B01J2219/00547 , B01J2219/00549 , B01J2219/00563 , B01J2219/00565 , B01J2219/00574 , B01J2219/00585 , B01J2219/00596 , B01J2219/00702 , B01L3/5027 , B01L2200/025 , B01L2300/022 , B01L2300/0819 , B01L2400/0487 , C40B60/14
摘要： The present invention relates to a device (10) for analyzing and archiving at least one combinatorial library of materials, comprising at least: a) an area for analyzing and holding materials, consisting at least of two sections (12) capable of holding at least two building blocks (20), b) means for feeding and/or discharging fluid media to and/or from at least one section (12), c) means for identifying the device (10) or the combinatorial library of materials or for identifying the device (10) and the combinatorial library of materials.
摘要翻译：本发明涉及一种用于分析和归档至少一种材料组合库的装置（10），该装置至少包括：a）用于分析和保持材料的区域，至少包括能够至少保持的两个部分（12）两个构件块（20），b）用于将流体介质供给和/或从至少一个区段（12）排出和/或排出的装置，c）用于识别装置（10）或组合材料库或用于识别设备（10）和材料组合库。

19. 发明申请

WO0173119A9 METHODS FOR GENOTYPING BY HYBRIDIZATION ANALYSIS 审中-公开
标题翻译：杂交分析的基因分型方法
公开(公告)号：WO0173119A9
公开(公告)日：2001-12-06
申请号：PCT/IB0100833
申请日：2001-03-29
申请人： CT FOR THE APPLIC OF MOLECULAR , KILIAN ANDRZEJ
发明人： KILIAN ANDRZEJ
IPC分类号： C12Q1/68 , C40B40/06 , C40B60/14
CPC分类号： C12Q1/6837 , B01J2219/00387 , B01J2219/00572 , B01J2219/00574 , B01J2219/00576 , B01J2219/00608 , B01J2219/00612 , B01J2219/0063 , B01J2219/00637 , B01J2219/00722 , C40B40/06 , C40B60/14 , C12Q2565/513 , C12Q2525/191
摘要： This invention provides methods for determining the genotype of organisms by hybridization analysis and, more specifically, to establishing the relatedness of individual organisms within a species. The present invention provides addressable arrays, comprising diversity panels of nucleic acid molecules, in which the molecules on the array are addressable or uniquely identifiable in some fashion. A diversity panel is the result of a method that can distinguish sequence differences between nucleic acid samples. As taught herein, a variety of methods may be used to generate diversity panels. Subsequent to the generation of the diversity panel, the nucleic acid products of the diversity panel are separated for application onto an array. The separated diversity panel is then delivered onto a substrate to create an addressable array and hybridized with labeled nucleic acids. The genotype of an organism is determined by the pattern of hybridization.
摘要翻译：本发明提供了通过杂交分析确定生物体基因型的方法，更具体地说，涉及建立物种内个体生物体的相关性。本发明提供可寻址阵列，其包含核酸分子的多样性组，其中阵列上的分子是可寻址的或以某种方式唯一可识别的。多样性小组是可以区分核酸样品之间的序列差异的方法的结果。如本文所教导的，可以使用各种方法来生成分集面板。在产生多样性组之后，将多样性组的核酸产物分离以施加到阵列上。然后将分离的多样性板递送到基质上以产生可寻址阵列并与标记的核酸杂交。有机体的基因型由杂交模式决定。

20. 发明申请

WO01077391A1 SPATIAL POSITIONING OF SPECTRALLY LABELED BEADS 审中-公开
标题翻译：光纤标线的空间定位
公开(公告)号：WO01077391A1
公开(公告)日：2001-10-18
申请号：PCT/US2001/011391
申请日：2001-04-06
IPC分类号： G01J3/28 , B01L3/00 , B82B1/00 , C40B40/06 , C40B60/14 , G01J3/443 , G01N15/00 , G01N15/14 , G01N21/25 , G01N21/31 , G01N21/64 , G01N35/00 , G06F3/00 , G06F13/42 , G06K7/00 , G06K7/12 , G06K19/06 , C12Q1/68 , C07H21/02 , C07H21/04 , C12P19/34 , G01N33/533 , G01N33/542 , G01N33/58 , G01P5/20
CPC分类号： G01N21/272 , B01J2219/00317 , B01J2219/00432 , B01J2219/005 , B01J2219/00574 , B01J2219/00576 , B01J2219/00578 , B01J2219/00585 , B01J2219/00596 , B01J2219/00648 , B01J2219/00657 , B01J2219/00659 , B01J2219/00677 , B01J2219/00707 , B01J2219/00722 , B01J2219/00743 , B01L3/5025 , B01L3/502715 , B01L3/502761 , B01L3/5085 , B01L3/545 , B01L2200/0668 , B01L2300/021 , B01L2300/0819 , B01L2300/0829 , B01L2400/0454 , B01L2400/0457 , B82Y30/00 , C40B40/06 , C40B60/14 , G01N21/25 , G01N21/253 , G01N21/274 , G01N21/278 , G01N21/6428 , G01N21/6452 , G01N21/6456 , G01N21/6486 , G01N21/6489 , G01N33/54373 , G01N2015/0092 , G01N2015/1472 , G01N2015/1497 , G01N2021/6441 , G01N2021/6482 , G01N2035/00158 , G01N2035/00742 , G01N2035/00752 , G01N2201/04 , G01N2201/06113 , G01N2201/12
摘要： Devices, systems, kits, and methods for detecting and/or identifying a plurality of spectrally labeled bodies well-suited for performing multiplexed assays. By spectrally labeling the beads with materials which generate identifiable spectra, a plurality of beads may be identified within the fluid. Reading of the beads is facilitated by restraining the beads in arrays, and/or using a focused laser.
摘要翻译：用于检测和/或识别非常适合于进行多重测定的多个光谱标记物质的装置，系统，试剂盒和方法。通过用产生可识别光谱的材料对珠粒进行光谱标记，可以在流体内识别多个珠粒。通过将阵列中的珠抑制和/或使用聚焦激光来促进珠的读取。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式