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1. 发明授权

US07609809B2 System and method of generating contour structures using a dose volume histogram 有权
标题翻译：使用剂量体积直方图生成轮廓结构的系统和方法
公开(公告)号：US07609809B2
公开(公告)日：2009-10-27
申请号：US11459143
申请日：2006-07-21
申请人： Jeffrey M. Kapatoes , Gustavo H. Olivera , Eric Schnarr , Weiguo Lu , Kenneth J. Ruchala , Paul J. Reckwerdt , John H. Hughes , Thomas R. Mackie
发明人： Jeffrey M. Kapatoes , Gustavo H. Olivera , Eric Schnarr , Weiguo Lu , Kenneth J. Ruchala , Paul J. Reckwerdt , John H. Hughes , Thomas R. Mackie
IPC分类号： A61N5/10 , H05G1/28
CPC分类号： A61N5/103 , A61N5/1042 , A61N5/1048 , A61N5/1049 , A61N5/1065 , A61N5/1069 , A61N2005/1074
摘要： A system and method of defining a new region of interest for an existing region of interest using a dose volume histogram. The method includes the acts of generating a dose volume histogram of radiation dose for a pre-existing region of interest, selecting a subset of the dose volume histogram, and defining a new region of interest that corresponds to the selected subset of the dose volume histogram.
摘要翻译：使用剂量体积直方图来定义现有感兴趣区域的新感兴趣区域的系统和方法。该方法包括产生用于预先存在的感兴趣区域的辐射剂量的剂量体积直方图的动作，选择剂量体积直方图的子集，以及定义对应于剂量体积直方图的选定子集的新的感兴趣区域。

2. 发明授权

US08767917B2 System and method of delivering radiation therapy to a moving region of interest 有权
标题翻译：将辐射治疗递送到感兴趣的移动区域的系统和方法
公开(公告)号：US08767917B2
公开(公告)日：2014-07-01
申请号：US11459074
申请日：2006-07-21
申请人： Kenneth J. Ruchala , Gustavo H. Olivera , Weiguo Lu , Eric Schnarr , John H. Hughes , Jeffrey M. Kapatoes , Thomas R. Mackie , Paul J. Reckwerdt
发明人： Kenneth J. Ruchala , Gustavo H. Olivera , Weiguo Lu , Eric Schnarr , John H. Hughes , Jeffrey M. Kapatoes , Thomas R. Mackie , Paul J. Reckwerdt
IPC分类号： A61N5/10
CPC分类号： A61N5/1049 , A61N5/103 , A61N5/1042 , A61N5/1067 , A61N2005/1061 , G06F19/00 , G06F19/321 , G06F19/3481 , G16H50/50
摘要： A system for and method of delivering radiation therapy to a moving region of interest is disclosed. The method, in one implementation, includes the acts of generating a plurality of treatment plans for providing radiation therapy, delivering radiation therapy to the patient following one of the plurality of treatment plans, monitoring the patient while providing radiation therapy, and changing the treatment plan based at least in part on monitoring the patient.
摘要翻译：公开了将辐射治疗递送到感兴趣的移动区域的系统和方法。该方法在一个实施中包括产生用于提供放射治疗的多个治疗计划的动作，在多个治疗计划中的一个治疗计划之后向患者传送放射疗法，在提供放射治疗的同时监测患者，以及改变治疗计划至少部分地基于监测患者。

3. 发明授权

US09731148B2 Radiation therapy imaging and delivery utilizing coordinated motion of gantry and couch 有权
公开(公告)号：US09731148B2
公开(公告)日：2017-08-15
申请号：US11459161
申请日：2006-07-21
申请人： Gustavo H. Olivera , Thomas R. Mackie , Kenneth J. Ruchala , Paul J. Reckwerdt , John H. Hughes , Jeffrey M. Kapatoes , Eric Schnarr , Weiguo Lu , Eric Schloesser , Gerald D. Fordyce, II , Tim Holzmann
发明人： Gustavo H. Olivera , Thomas R. Mackie , Kenneth J. Ruchala , Paul J. Reckwerdt , John H. Hughes , Jeffrey M. Kapatoes , Eric Schnarr , Weiguo Lu , Eric Schloesser , Gerald D. Fordyce, II , Tim Holzmann
IPC分类号： A61B5/00 , A61N5/10
CPC分类号： A61N5/1042 , A61N5/1049 , A61N5/1069
摘要： A system and method of delivering a radiation therapy treatment plan to a patient. The treatment plan is delivered using a radiation therapy system including a moveable support for supporting a patient, a gantry moveable relative to the support and supporting a radiation source and multi-leaf collimator for modulating the radiation source. The support and gantry are moved during delivery of the treatment plan.

4. 发明授权

US07773788B2 Method and system for evaluating quality assurance criteria in delivery of a treatment plan 有权
标题翻译：评估治疗计划的质量保证标准的方法和系统
公开(公告)号：US07773788B2
公开(公告)日：2010-08-10
申请号：US11459152
申请日：2006-07-21
申请人： Weiguo Lu , Gustavo H. Olivera , Jeffrey M. Kapatoes , Kenneth J. Ruchala , Eric Schnarr , John H. Hughes , Thomas R. Mackie , Paul J. Reckwerdt
发明人： Weiguo Lu , Gustavo H. Olivera , Jeffrey M. Kapatoes , Kenneth J. Ruchala , Eric Schnarr , John H. Hughes , Thomas R. Mackie , Paul J. Reckwerdt
IPC分类号： G06K9/00
CPC分类号： A61N5/103 , A61N5/1042 , A61N5/1048 , A61N5/1049 , A61N5/1065 , A61N5/1067 , A61N5/1069 , A61N5/107 , A61N5/1075
摘要： System and method of evaluating quality assurance criteria related to the delivery of a radiation therapy treatment plan. The method includes the acts of acquiring image data of a patient, generating a treatment plan for the patient based at least in part on the image data, the treatment plan including a calculated radiation dose to be delivered to the patient, acquiring an on-line image of the patient in substantially a treatment position, delivering at least a portion of the calculated radiation dose to the patient, monitoring quality assurance criteria related to the delivery of the treatment plan, calculating the radiation dose received by the patient, and determining whether delivery of the treatment plan occurred as intended based on the quality assurance criteria and the radiation dose received by the patient.
摘要翻译：评估与放射治疗计划相关的质量保证标准的系统和方法。该方法包括获取患者的图像数据的动作，至少部分地基于图像数据生成针对患者的治疗计划，治疗计划包括计算出的要递送给患者的辐射剂量，获取在线将患者的图像基本上处于治疗位置，将计算的辐射剂量的至少一部分递送给患者，监测与治疗计划的递送相关的质量保证标准，计算患者接收的辐射剂量，以及确定是否递送的治疗计划根据质量保证标准和患者接受的放射剂量进行预期的发生。

5. 发明授权

US07639854B2 Method and system for processing data relating to a radiation therapy treatment plan 有权
标题翻译：用于处理与放射治疗治疗计划有关的数据的方法和系统
公开(公告)号：US07639854B2
公开(公告)日：2009-12-29
申请号：US11459108
申请日：2006-07-21
申请人： Eric Schnarr , Kenneth J. Ruchala , Gustavo H. Olivera , Weiguo Lu , Jeffrey M. Kapatoes , Jason Haimerl , John H. Hughes , Thomas R. Mackie
发明人： Eric Schnarr , Kenneth J. Ruchala , Gustavo H. Olivera , Weiguo Lu , Jeffrey M. Kapatoes , Jason Haimerl , John H. Hughes , Thomas R. Mackie
IPC分类号： G06K9/00 , A61B5/05
CPC分类号： A61N5/103 , A61N5/1037 , A61N5/1038 , A61N5/1042 , A61N5/1048 , A61N5/1049 , A61N5/1065 , A61N5/1067 , A61N5/1069 , A61N5/107
摘要： A system and method of automatically processing data relating to a radiation therapy treatment plan. The method includes the acts of acquiring image data of a patient, generating a treatment plan for the patient based at least in part on the image data, the treatment plan including a calculated radiation dose to be delivered to the patient, acquiring an on-line image of the patient in substantially a treatment position, delivering at least a portion of the calculated radiation dose to the patient, and automatically recalculating the radiation dose received by the patient.
摘要翻译：一种自动处理与放射治疗治疗计划有关的数据的系统和方法。该方法包括获取患者的图像数据的动作，至少部分地基于图像数据生成针对患者的治疗计划，治疗计划包括计算出的要递送给患者的辐射剂量，获取在线将患者的图像基本上处于治疗位置，将计算出的辐射剂量的至少一部分递送给患者，并自动重新计算由患者接收的辐射剂量。

6. 发明授权

US07639853B2 Method of and system for predicting dose delivery 有权
标题翻译：预测剂量递送的方法和系统
公开(公告)号：US07639853B2
公开(公告)日：2009-12-29
申请号：US11459066
申请日：2006-07-21
申请人： Gustavo H. Olivera , Kenneth J. Ruchala , Eric Schnarr , Jeffrey M. Kapatoes , Weiguo Lu , Jason Haimerl , John H. Hughes , Thomas R. Mackie
发明人： Gustavo H. Olivera , Kenneth J. Ruchala , Eric Schnarr , Jeffrey M. Kapatoes , Weiguo Lu , Jason Haimerl , John H. Hughes , Thomas R. Mackie
IPC分类号： G06K9/00 , A61B5/05
CPC分类号： A61N5/103 , A61N5/1038 , A61N5/1042 , A61N5/1048 , A61N5/1049 , A61N5/1065 , A61N5/1069
摘要： A system and method of predicting a radiation dose to be delivered to a patient. The method includes the acts of generating a first image of at least a portion of the patient, defining a treatment plan for the patient, generating a second image of at least a portion of the patient while the patient is substantially in a treatment position, updating the patient profile with the second image, and predicting the radiation dose to be delivered to the patient based upon the patient profile and the treatment plan.
摘要翻译：一种预测要传送给患者的辐射剂量的系统和方法。该方法包括产生患者的至少一部分的第一图像的动作，为患者定义治疗计划，在患者基本处于治疗位置时产生患者的至少一部分的第二图像，更新患者轮廓与第二图像，并且基于患者概况和治疗计划预测要递送给患者的辐射剂量。

7. 发明授权

US08406844B2 Method for modification of radiotherapy treatment delivery 有权
标题翻译：放射治疗传递的修改方法
公开(公告)号：US08406844B2
公开(公告)日：2013-03-26
申请号：US10506866
申请日：2003-03-06
申请人： Kenneth J. Ruchala , Gustavo H. Olivera , Jeffrey M. Kapatoes , Paul J. Reckwerdt , Weiguo Lu , John H. Hughes
发明人： Kenneth J. Ruchala , Gustavo H. Olivera , Jeffrey M. Kapatoes , Paul J. Reckwerdt , Weiguo Lu , John H. Hughes
IPC分类号： A61B5/05
CPC分类号： A61N5/103 , A61N5/1038 , A61N5/1065 , A61N5/1067 , A61N5/1069 , A61N2005/1061 , G06F19/00
摘要： A method of contoured-anatomy dose repositioning (CADR) as a means to automatically reposition a patient to better recover the planned dose distribution without reoptimizinq the treatment plan. CADR utilizes planning CT images, the planned dose distribution, and on-line images for repositioning dose distribution on a given day. Contours are also placed upon the images using manual, automatic, template-based, or other techniques. CADR then optimizes the rigid-body repositioning of the patient so that the daily dose distribution closely matches the planned dose distribution.
摘要翻译：一种轮廓解剖学剂量重新定位（CADR）的方法，作为自动重新定位患者的手段，以更好地恢复计划的剂量分布，而无需重新计算治疗计划。 CADR利用计划的CT图像，计划的剂量分布和在线图像在给定的一天重新定位剂量分布。使用手动，自动，基于模板或其他技术的轮廓也被放置在图像上。然后，CADR优化患者的刚体重新定位，使得日剂量分布与计划的剂量分布密切相关。

8. 发明授权

US08232535B2 System and method of treating a patient with radiation therapy 有权
标题翻译：用放射线治疗患者的系统和方法
公开(公告)号：US08232535B2
公开(公告)日：2012-07-31
申请号：US11431319
申请日：2006-05-10
申请人： Gustavo H. Olivera , Thomas R. Mackie , Jeffrey M. Kapatoes , John H. Hughes , Kenneth J. Ruchala , Paul J. Reckwerdt
发明人： Gustavo H. Olivera , Thomas R. Mackie , Jeffrey M. Kapatoes , John H. Hughes , Kenneth J. Ruchala , Paul J. Reckwerdt
IPC分类号： G21G4/00
CPC分类号： A61N5/1042 , A61B6/027 , A61N5/1049
摘要： A radiation therapy treatment system and method of treating a patient with radiation. The system integrates positioning of the patient, treatment planning, and delivery of the plan. As a result of the integration of imaging capabilities into the treatment apparatus, and efficient processes for contouring and planning, a patient can be treated in approximately 20 minutes or less. The method includes acquiring image data from the patient, defining a target region with one or more predefined shapes, generating a treatment plan based on the defined target region, and delivering radiation to the target region.
摘要翻译：放射疗法治疗系统和治疗患者放射线的方法。该系统整合了患者的定位，治疗计划和计划的交付。作为将成像能力整合到治疗装置中的结果以及用于轮廓和规划的有效过程，可以在大约20分钟或更短时间内对患者进行治疗。该方法包括从患者获取图像数据，用一个或多个预定形状定义目标区域，基于所定义的目标区域生成治疗计划，以及将辐射传送到目标区域。

9. 发明授权

US6018763A High performance shared memory for a bridge router supporting cache coherency 失效
标题翻译：支持高速缓存一致性的桥接路由器的高性能共享内存
公开(公告)号：US6018763A
公开(公告)日：2000-01-25
申请号：US858182
申请日：1997-05-28
申请人： John H. Hughes , Mark S. Isfeld
发明人： John H. Hughes , Mark S. Isfeld
IPC分类号： G06F12/08 , H04L12/56 , G06F15/167 , G06F15/17
CPC分类号： H04L12/5693 , G06F12/0822 , H04L49/90 , H04L49/901 , H04L49/9047
摘要： An internetwork device manages the flow of packets of I/O data among a plurality of network interface devices. The internetwork device includes an I/O bus which is coupled to the plurality of network interface devices and a shared memory, for storing packets of I/O data and control structures needed by the plurality internetwork interface devices. The shared memory is also coupled to a processor bus, which connects to a processor and a processor memory. The processor memory is isolated from the shared memory, and is used for storing routines and internetworking information involved in routing packets of I/O data among the plurality of network interface devices. In this way, accesses between the processor and the processor memory are decoupled from accesses between the plurality of network interface devices. System performance is improved by storing copies of items from the shared memory in a processor cache located near the processor. Consistency rules are enforced between items in the shared memory and copies of the items in the processor cache through communications across the processor bus. Communications across the processor bus to enforce consistency rules are minimized by maintaining a shadow tag store near the shared memory, which keeps track of the items from the shared memory which are copied in the processor cache. Communications to enforce consistency rules only take place if the shadow tag store indicates that the processor cache contains an item of data from the shared memory which has been read from or written to.
摘要翻译：互联网络设备管理多个网络接口设备之间的I / O数据分组的流。互联网络设备包括耦合到多个网络接口设备的I / O总线和用于存储多个互联网络接口设备所需的I / O数据和控制结构的分组的共享存储器。共享存储器还耦合到处理器总线，其连接到处理器和处理器存储器。处理器存储器与共享存储器隔离，并且用于存储在多个网络接口设备之间路由I / O数据分组中涉及的例程和互联网络信息。以这种方式，处理器和处理器存储器之间的访问与多个网络接口设备之间的访问分离。通过将来自共享存储器的项目副本存储在位于处理器附近的处理器高速缓存器中来提高系统性能。一致性规则在共享存储器中的项目和处理器缓存中的项目的副本之间通过整个处理器总线的通信来执行。通过在共享存储器附近保持阴影标签存储来保持处理器总线上的通信，从而实现一致性规则的最小化，共享存储器可以跟踪共享存储器中复制在处理器高速缓存中的项目。如果影子标签存储指示处理器缓存包含从已经被读取或写入的共享存储器中的数据项，则仅执行用于强制一致性规则的通信。

10. 发明授权

US5927624A Comminuting chamber and attachments therefor 失效
标题翻译：服务室及其附件
公开(公告)号：US5927624A
公开(公告)日：1999-07-27
申请号：US919402
申请日：1997-08-28
申请人： John H. Hughes
发明人： John H. Hughes
IPC分类号： B02C18/06 , B02C13/286
CPC分类号： B02C18/067
摘要： A comminuting chamber (24) and attachments therefor for comminuting solid material into a particulate form is disclosed. The chamber includes a rotatable sidewall (40), a bottom (41) disposed across an end of the sidewall, and a toothed disk (32) rotatably mounted within the chamber adjacent the bottom. At least one attachment (28) is secured to the bottom of the chamber and provides a variety of surfaces which engage and reorient material being comminuted in the chamber. The attachment may include a plate (30) that extends horizontally in a plane adjacent the bottom. An edge of the plate may further have a flange (80) that extends outward and downward toward the chamber bottom. The attachment may also include a rotary scrubber (38) having a hub (56) and a plurality of arms (58) extending radially outward from the hub. The scrubber is either rotatably mounted on the plate or on the chamber bottom. Where the attachment includes a plate, riser plate members (88) extending upward into the chamber may be attached to the plate. The plate may also include upward-extending scraper plates (92) adjacent the comminuting chamber sidewall for scraping material that has collected on the chamber sidewall as the sidewall rotates. By engaging and reorienting the material being comminuted in the chamber, the attachment surfaces improve the efficiency of the comminuter.
摘要翻译：公开了一种粉碎室（24）及其附件，用于将固体材料粉碎成颗粒形式。所述腔室包括可旋转侧壁（40），横跨所述侧壁的端部设置的底部（41）和与所述底部相邻地可旋转地安装在所述腔室内的齿形盘（32）。至少一个附件（28）固定到腔室的底部，并且提供各种表面，其接合并重新定向在腔室中被粉碎的材料。附件可以包括在邻近底部的平面中水平延伸的板（30）。板的边缘还可以具有向腔室底部向外和向下延伸的凸缘（80）。附件还可以包括具有毂（56）和从轮毂径向向外延伸的多个臂（58）的旋转洗涤器（38）。洗涤器可旋转地安装在板上或室底部。在附件包括板的情况下，向上延伸到室中的提升板构件（88）可以附接到板。该板还可以包括邻近粉碎室侧壁的向上延伸的刮板（92），用于当侧壁旋转时用于刮擦收集在室侧壁上的材料。通过接合和重新定向在室中粉碎的材料，附着表面提高了粉碎机的效率。

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