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1. 发明申请

US20190126067A1 TIME OPTIMIZED RADIATION TREATMENT 审中-公开
公开(公告)号：US20190126067A1
公开(公告)日：2019-05-02
申请号：US16091515
申请日：2017-04-04
申请人： Varian Medical System Particle Therapy GmbH
发明人： Holger Goebel , Isabel Huth
IPC分类号： A61N5/10
CPC分类号： A61N5/1031 , A61N5/103 , A61N5/1037 , A61N5/1039 , A61N5/1043 , A61N5/1049 , A61N5/1067 , A61N5/107 , A61N5/1071 , A61N5/1077 , A61N2005/1087
摘要： In one embodiment, a method includes receiving treatment information relating to a treatment plan for proton- or ion-beam therapy intended to irradiate a target tissue; receiving machine-limitation information relating to one or more limitations of one or more machines involved in the proton- or ion-beam therapy; determining a time-optimized beam current for a proton or ion beam based on the treatment information and the machine-limitation information, wherein the time-optimized beam current minimizes the time required to deliver a required quantity of monitor units to one of a plurality of spots, wherein each of the plurality of spots is a particular area of the target tissue; and delivering the time-optimized beam current to the particular area.

2. 发明申请

US20180326223A1 SYSTEMS AND METHODS OF ACCOUNTING FOR SHAPE CHANGE DURING RADIOTHERAPY 审中-公开
公开(公告)号：US20180326223A1
公开(公告)日：2018-11-15
申请号：US15839381
申请日：2017-12-12
申请人： Elekta, Inc.
发明人： Virgil WILLCUT
IPC分类号： A61N5/10
CPC分类号： A61N5/1037 , A61N5/1031 , A61N5/1039 , A61N5/1045 , A61N5/107 , A61N2005/1052 , A61N2005/1055 , A61N2005/1061
摘要： Embodiments of the disclosure may be directed to a system for generating a motion target volume representative of shape changes of a target region in a patient. The system may comprise at least one computer system configured to receive a plurality of electronic medical images that include the target region, and each of the plurality of images may have been taken at a different time point. The computer system may be configured to define a three-dimensional volume containing the target region in each of the plurality of images, and the three-dimensional volume may be different in at least two of the plurality of images due to differences in shape of the target region in the at least two images. The computer system may also be configured to co-register the three-dimensional volumes and generate the motion target volume, wherein the motion target volume encompasses each of the three-dimensional volumes.

3. 发明申请

US20180264289A1 CANCER THERAPY SYSTEM TREATMENT BEAM PROGRESSION AND METHOD OF USE THEREOF 审中-公开
公开(公告)号：US20180264289A1
公开(公告)日：2018-09-20
申请号：US15823070
申请日：2017-11-27
申请人： Susan L. Michaud , W. Davis Lee
发明人： Susan L. Michaud , W. Davis Lee
IPC分类号： A61N5/10
CPC分类号： A61N5/1067 , A61B6/032 , A61B6/037 , A61B6/0492 , A61B6/4014 , A61B6/4258 , A61B6/4429 , A61B6/4441 , A61B6/4452 , A61B6/5205 , A61B6/547 , A61N5/1037 , A61N5/1043 , A61N5/1049 , A61N5/1069 , A61N5/107 , A61N5/1075 , A61N5/1077 , A61N5/1078 , A61N5/1081 , A61N5/1082 , A61N2005/1051 , A61N2005/1054 , A61N2005/1061 , A61N2005/1074 , A61N2005/1076 , A61N2005/1087 , A61N2005/1089 , A61N2005/1095 , A61N2005/1097 , E04F15/00 , E04H3/08 , F16M7/00 , G01T1/20 , G21K1/08 , G21K5/04
摘要： The invention comprises a method and apparatus for treating a tumor with positively charged particles, comprising the steps of: (1) transporting the positively charged particles sequentially from an accelerator, along a beam transport path, through a nozzle system, and along a treatment beam path and (2) while scanning the treatment beam path along each of a set of vectors for treating the tumor, on average for the set of vectors, intentionally deviating the treatment beam path from a current vector of the set of vectors off of the current vector by at least one-eighth of a treatment beam diameter at least once for every twenty movements of the treatment beam.

4. 发明申请

US20180253846A1 MANIPULATION OF A RESPIRATORY MODEL VIA ADJUSTMENT OF PARAMETERS ASSOCIATED WITH MODEL IMAGES 审中-公开
公开(公告)号：US20180253846A1
公开(公告)日：2018-09-06
申请号：US15971694
申请日：2018-05-04
申请人： Accuray Incorporated
发明人： Kolos Lugosi , Matthew Core , Robert Kahn
IPC分类号： G06T7/00 , G06F3/0484 , A61B6/00 , G06T7/38 , G06T7/246 , A61N5/10 , A61B6/03 , G06T11/60 , G06T17/00 , G06T17/10 , G06T19/20 , A61B90/00 , A61B5/08 , A61B5/11 , A61B5/113 , A61B6/02 , A61B6/12 , A61B34/20
CPC分类号： G06T7/0012 , A61B5/0816 , A61B5/1127 , A61B5/113 , A61B6/022 , A61B6/032 , A61B6/12 , A61B6/4014 , A61B6/4085 , A61B6/4266 , A61B6/4464 , A61B6/463 , A61B6/465 , A61B6/5223 , A61B6/5235 , A61B6/5264 , A61B6/5288 , A61B6/5294 , A61B2034/2055 , A61B2090/364 , A61B2090/3945 , A61B2090/3966 , A61N5/1037 , A61N5/1067 , A61N5/1083 , A61N2005/1051 , A61N2005/1061 , A61N2005/1062 , G06F3/04842 , G06T7/11 , G06T7/246 , G06T7/251 , G06T7/38 , G06T11/60 , G06T17/00 , G06T17/10 , G06T19/20 , G06T2200/08 , G06T2207/10116 , G06T2207/30241
摘要： A method and apparatus for manipulation of a respiratory model via adjustment of parameters associated with model images is described. A subset of the images that are used with the model that is associated with the position and motion of a targeted region of the patient to receive radiation treatment may be identified. The subset of images may be sorted. A graphical user interface (GUI) that identifies two or more of the images of the sorted subset may be provided. A selection associated with one of the images of the sorted subset may be received by the GUI. Furthermore, a new model to identify the targeted region based on the selection that is associated with one of the two or more images may be generated.

5. 发明申请

US20180243585A1 IMAGE GUIDANCE FOR RADIATION THERAPY 审中-公开
公开(公告)号：US20180243585A1
公开(公告)日：2018-08-30
申请号：US15957056
申请日：2018-04-19
申请人： Elekta, Inc.
发明人： Martin Emile Lachaine , Fabienne Lathuiliere , Michel Moreau
IPC分类号： A61N5/10 , A61B6/03 , A61B8/08 , G06T7/11 , G06T7/33
CPC分类号： A61N5/1065 , A61B5/055 , A61B6/032 , A61B8/085 , A61B2034/2065 , A61B2090/367 , A61N5/1037 , A61N5/1038 , A61N5/1039 , A61N5/1049 , A61N2005/1055 , A61N2005/1058 , A61N2005/1061 , G06T7/11 , G06T7/337 , G06T2207/10081 , G06T2207/10088 , G06T2207/10132 , G06T2207/20021 , G06T2207/30096
摘要： An adaptive therapy delivery system can receive imaging information including a volumetric image comprising a target such as a tumor or one or more other structures, and can receive imaging information corresponding to one or more imaging slices comprising different portions of the target, such as imaging slices acquired at different times after acquisition of the volumetric image. The system can spatially register information from an earlier-acquired image with a portion of the target included in a later-acquired one of the imaging slices. The system can then determine an updated location of the target indicated by the spatially-registered information. Using the updated location, the system can generate an updated therapy protocol to control delivery of a therapy beam.

6. 发明授权

US10037863B2 Continuous ion beam kinetic energy dissipater apparatus and method of use thereof 有权
公开(公告)号：US10037863B2
公开(公告)日：2018-07-31
申请号：US15676926
申请日：2017-08-14
申请人： Mark R. Amato , W. Davis Lee
发明人： Mark R. Amato , W. Davis Lee
IPC分类号： H01J37/08 , A61B6/03 , A61N5/10 , A61B6/00
CPC分类号： H01J37/08 , A61B6/032 , A61B6/037 , A61B6/4035 , A61B6/4085 , A61B6/4258 , A61B6/4266 , A61B6/4435 , A61B6/5205 , A61N5/1037 , A61N5/1039 , A61N5/1049 , A61N5/1067 , A61N5/1069 , A61N5/107 , A61N5/1077 , A61N5/1082 , A61N2005/1051 , A61N2005/1054 , A61N2005/1061 , A61N2005/1087 , A61N2005/1095 , A61N2005/1097 , G21K1/10 , G21K5/04 , H01J2237/004
摘要： The invention comprises a method and apparatus for slowing positively charged particles, comprising the steps of: (1) transporting the positively charged particles from an accelerator, along a beam transport line, and into a nozzle system; (2) placing a first liquid in a first chamber in a beam path of the positively charged particles; (3) placing a second liquid in a second chamber in the beam path of the positively charged particles; (4) moving the first and second chamber with the nozzle system; (5) slowing the positively charged particles using the first liquid and the second liquid; (6) moving the first chamber in a first direction to yield a longer first pathlength of the positively charged particles through the first chamber; and (7) moving the second chamber opposite the first direction to yield a longer second pathlength of the positively charged particles through the second chamber.

7. 发明申请

US20180192505A1 HOMOLOGOUS DUAL-ENERGY ACCELERATOR AND ACCELERATOR THERAPY DEVICE 审中-公开
公开(公告)号：US20180192505A1
公开(公告)日：2018-07-05
申请号：US15552581
申请日：2016-04-14
申请人： SUZHOU LINATECH MEDICAL SCIENCE AND TECHNOLOGY CO., LTD.
发明人： Jonathan Yi YAO
IPC分类号： H05H5/03 , A61N5/10
CPC分类号： H05H5/03 , A61N5/00 , A61N5/1037 , H05H9/044 , H05H9/048 , H05H2007/002 , H05H2277/11
摘要： The present invention discloses a homologous dual-energy accelerator and a therapy device comprising the homologous accelerator. The homologous dual-energy accelerator comprises an electron emitting device and an accelerating device, wherein the electron emitting device is located at the input end of the accelerating device, and electrons generated by the electron emitting device are emitted from the output end of the accelerating device after being accelerated by the accelerating device; the homologous dual-energy accelerator further comprises at least one separation deflection device which is arranged on the output end side of the accelerating device and used for changing the motion trail of partial electrons among the electrons accelerated by the accelerating device. The homologous dual-energy accelerator has the advantages that the inventor discovers that the speeds and energy of all electrons are not completely same after the electrons are accelerated by the accelerating device; the inventor uses the separation deflection device arranged on the output end side of the accelerating device through the discovery, the motion trail of partial electrons having relatively low energy level among the particles accelerated by the accelerating device is forcibly changed, the electrons having different energy levels in a homologous electron beam are separated, and two energy levels of electron beams are thus obtained, wherein the high-energy electron beam continues an original path and is used for radiotherapy, and the other path of low-energy electron beam is used for tracking lesions and detecting the therapeutic effect.

8. 发明申请

US20180185673A1 MULTIPLE CATION CANCER THERAPY APPARATUS AND METHOD OF USE THEREOF 审中-公开
公开(公告)号：US20180185673A1
公开(公告)日：2018-07-05
申请号：US15907076
申请日：2018-02-27
申请人： W. Davis Lee , Mark R. Amato , Scott Penfold , Stephen L. Spotts
发明人： W. Davis Lee , Mark R. Amato , Scott Penfold , Stephen L. Spotts
IPC分类号： A61N5/10 , G21K1/087 , G21K5/04 , A61B6/03 , G21K1/093 , H01J35/14
CPC分类号： A61N5/1077 , A61B6/00 , A61B6/03 , A61B6/032 , A61B6/4258 , A61B6/5205 , A61N5/1037 , A61N5/1039 , A61N5/1044 , A61N5/1049 , A61N5/1067 , A61N5/1069 , A61N5/107 , A61N5/1082 , A61N2005/1051 , A61N2005/1052 , A61N2005/1054 , A61N2005/1061 , A61N2005/1074 , A61N2005/1087 , A61N2005/1095 , A61N2005/1097 , G21K1/08 , G21K1/087 , G21K1/093 , G21K5/04 , H01J35/14
摘要： The invention comprises a method and apparatus for imaging and/or treating a tumor of a patient using multiple ion types, such as a cations with one, two, or more mass-to-charge ratios and/or electrons, where the multiple ion types are accelerated, at separate times, using a single accelerator, and the multiple ion types are used to treat different depths into a tumor of a patient, where the patient is optionally maintained in a single treatment position relative to a patient positioning system during treatment.

9. 发明授权

US09990731B2 Systems and methods for evaluating motion tracking for radiation therapy 有权
公开(公告)号：US09990731B2
公开(公告)日：2018-06-05
申请号：US14994766
申请日：2016-01-13
申请人： Varian Medical Systems International AG
发明人： Stefan G. Scheib , Christof Baltes , Kristijan Macek
IPC分类号： G06T7/00 , G06T7/20 , G06K9/62 , A61N5/10
CPC分类号： A61N5/1037 , A61B6/06 , A61N5/1047 , A61N5/1049 , A61N5/1071 , A61N5/1075 , A61N2005/1054 , A61N2005/1072 , A61N2005/1076 , G06K9/6267 , G06T7/0012 , G06T7/0016 , G06T7/20 , G06T2207/10016 , G06T2207/10116
摘要： An apparatus includes: a processor configured for obtaining a first image that corresponds with a first multi-leaf collimator (MLC) configuration, wherein the first image is generated when the MLC is stationary, obtaining a second image that corresponds with a second MLC configuration, wherein the second image is generated when the MLC and/or another component of a radiation machine is being operated to track a motion, and performing an analysis based at least in part on the first image and the second image to obtain a result; and a non-transitory medium for storing the result.

10. 发明授权

US09974978B2 Scintillation array apparatus and method of use thereof 有权
公开(公告)号：US09974978B2
公开(公告)日：2018-05-22
申请号：US15239773
申请日：2016-08-17
申请人： W. Davis Lee , Mark R. Amato , Stephen L. Spotts , James P. Bennett
发明人： W. Davis Lee , Mark R. Amato , Stephen L. Spotts , James P. Bennett
IPC分类号： A61N5/00 , A61N5/10 , A61B6/03 , G21K1/093 , G21K5/04 , A61B6/00 , G01N23/04 , A61B6/04
CPC分类号： A61N5/1069 , A61B6/03 , A61B6/032 , A61B6/0457 , A61B6/4014 , A61B6/4092 , A61B6/4258 , A61B6/4266 , A61B6/4417 , A61B6/4435 , A61B6/5205 , A61B6/5247 , A61N5/1037 , A61N5/1039 , A61N5/1067 , A61N5/107 , A61N5/1077 , A61N5/1082 , A61N2005/105 , A61N2005/1054 , A61N2005/1061 , A61N2005/1087 , A61N2005/1095 , A61N2005/1097 , G01N23/046 , G01N2223/107 , G01N2223/203 , G21K1/093 , G21K5/04
摘要： A scintillation material is longitudinally packaged in a circumferentially surrounding sheath, where the sheath has a lower index of refraction than the scintillation material, to form a scintillation optic or scintillation fiber optic. The scintillation material yields secondary photons upon passage of a charged particle beam, such as a positively charged residual particle beam having transmitted through a sample. The internally generated secondary photons within the sheath are guided to a detector element by the difference in index of refraction. Multiple scintillation optics are assembled to form a two-dimensional scintillation array coupled to a two-dimensional detector array, such as for use in determination of state of the residual charged particle beam, determination of an exit point of the particle beam from the sample, path of the treatment beam, and/or tomographic imaging.

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