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1. 发明授权

US06632404B1 Automatically actuated parallel sample injector valve 失效
标题翻译：自动启动平行进样阀
公开(公告)号：US06632404B1
公开(公告)日：2003-10-14
申请号：US09631442
申请日：2000-08-02
申请人： J. Christopher Freitag , Miroslav Petro
发明人： J. Christopher Freitag , Miroslav Petro
IPC分类号： B01L1100
CPC分类号： G01N35/1097 , B01J2219/00324 , B01J2219/00391 , B01J2219/00407 , B01J2219/00707 , B01L3/567 , B01L2300/0829 , B01L2300/0874 , B01L2300/0887 , B01L2400/0487 , B01L2400/0644 , B01L2400/065 , C40B60/14 , F16K11/0655 , G01N30/20 , G01N30/24 , G01N2030/202 , G01N2030/204 , Y10T137/4456 , Y10T137/4471
摘要： A sample injector valve capable of introducing multiple samples of material into multiple liquid or gas streams is provided. Such a valve is particularly useful for injecting multiple samples under pressure into a combinatorial chemistry system with moving streams of fluid, such as a parallel pressure reactor or a rapid flow analysis system using multi-channel or parallel chromatography and related techniques. The valve is further capable of functioning on a small scale with automatic sampling equipment.
摘要翻译：提供了能够将多个样品材料引入多个液体或气体流中的样品注射器阀。这种阀特别适用于在压力下将多个样品注入组合化学系统中，该系统具有移动的流体流，例如使用多通道或平行色谱和相关技术的平行压力反应器或快速流动分析系统。阀门还能够在小规模的情况下自动采样设备。

2. 发明授权

US06936471B2 Instrument for high throughput measurement of material physical properties and method of using same 失效
标题翻译：用于材料物理性能高通量测量的仪器及其使用方法
公开(公告)号：US06936471B2
公开(公告)日：2005-08-30
申请号：US09779149
申请日：2001-02-08
申请人： Damian Hajduk , Eric Carlson , J. Christopher Freitag , Oleg Kolosov , James R. Engstrom , Adam Safir , Ravi Srinivasan , Leonid Matsiev
发明人： Damian Hajduk , Eric Carlson , J. Christopher Freitag , Oleg Kolosov , James R. Engstrom , Adam Safir , Ravi Srinivasan , Leonid Matsiev
IPC分类号： G01N11/00 , B01L3/00 , G01N1/28 , G01N3/02 , G01N3/08 , G01N3/20 , G01N3/32 , G01N5/00 , G01N19/00 , G01N29/02 , G01N29/22 , G01N37/00 , G01N31/00 , G01N3/00
CPC分类号： B01L3/5085 , B01J2219/00707 , B01J2219/00718 , G01N5/00 , G01N11/00 , G01N19/00 , G01N29/02 , G01N29/222 , G01N2203/0286 , G01N2291/02466 , G01N2291/0255 , G01N2291/02818 , G01N2291/106 , Y10T436/12
摘要： An apparatus and method for screening combinatorial libraries of materials by measuring the response of individual library members to mechanical perturbations is described. The apparatus generally includes a sample holder for containing the library members, an array of probes for mechanically perturbing individual library members, and an array of sensors for measuring the response of each of the library members to the mechanical perturbations. Library members undergoing screening make up a sample array, and individual library members constitute elements of the sample array that are confined to specific locations on the sample holder. During screening, the apparatus mechanically perturbs individual library members by displacing the sample array (sample holder) and the array of probes. Typically, all of the elements of the sample array are perturbed simultaneously, but the apparatus also can also perturb individual or groups of sample array elements sequentially. The flexible apparatus and method can screen libraries of materials based on many different bulk physical properties, including Young's modulus (flexure, uniaxial extension, biaxial compression, and shear); hardness (indentation), failure (stress and strain at failure, toughness), adhesion (tack, loop tack), and flow (viscosity, melt flow indexing, and rheology), among others.
摘要翻译：描述了通过测量单个文库成员对机械扰动的响应来筛选材料组合文库的装置和方法。该装置通常包括用于容纳库构件的样本保持器，用于机械扰乱各个库构件的探针阵列，以及用于测量每个库构件对机械扰动的响应的传感器阵列。正在进行筛选的图书馆成员组成一个样本数组，单独的图书馆成员构成了样本数组的元素，它们限于样本持有者的特定位置。在筛选期间，设备通过移位样品阵列（样品架）和探针阵列来机械地干扰各个库成员。通常，样本阵列的所有元素都被同时扰动，但是该装置也可以顺序扰乱单个或组的样本阵列元素。灵活的装置和方法可以基于许多不同的体积物理性质（包括杨氏模量（挠曲，单轴延伸，双轴压缩和剪切））筛选材料库; 硬度（压痕），破坏（破坏时的应力和应变，韧性），粘附性（粘性，环粘性）和流动性（粘度，熔体流动指数和流变学）等。

3. 发明申请

US20100080733A1 NEEDLE ASSEMBLY FOR ASPIRATING AND DISPENSING FROM SEALED CONTAINERS 审中-公开
标题翻译：用于吸收和分配密封容器的针头组件
公开(公告)号：US20100080733A1
公开(公告)日：2010-04-01
申请号：US12489159
申请日：2009-06-22
申请人： Eric D. Carlson , Peijun Cong , William H. Chandler, JR. , Peter J. Desrosiers , J. Christopher Freitag , John F. Varni
发明人： Eric D. Carlson , Peijun Cong , William H. Chandler, JR. , Peter J. Desrosiers , J. Christopher Freitag , John F. Varni
IPC分类号： G01N1/02 , B01L3/02
CPC分类号： B01L3/50255 , B01J19/0046 , B01J2219/00283 , B01J2219/00308 , B01J2219/00315 , B01J2219/00335 , B01J2219/00364 , B01J2219/00373 , B01J2219/00423 , B01J2219/00481 , B01J2219/00484 , B01J2219/00495 , B01J2219/00585 , B01J2219/00689 , B01J2219/00695 , B01J2219/00698 , B01J2219/00702 , B01J2219/00704 , B01J2219/00725 , B01J2219/00756 , B01L3/06 , B01L7/00 , B01L2300/0829 , B01L2300/185 , C40B40/04 , C40B40/10 , C40B60/10 , C40B60/14 , G01N5/045 , G01N21/23 , G01N21/65 , G01N25/04 , G01N33/15 , G01N33/54366 , G01N35/028 , G01N2013/006 , G01N2021/651 , G01N2500/00 , G16C20/20 , G16C20/90 , Y10T117/10
摘要： A needle assembly has at least one guide member supported by a first body for sliding movement between an extended position and a retracted position. A second body is attached to the guide member. A biasing member biases the guide member to the extended position. A liquid handling needle is coupled to the first body so sliding movement of the guide member toward the retracted position retracts the second body relative to the liquid handling needle. The second body is adapted to contact a sealed receptacle. The biasing member urges the guide member toward said extended position during insertion and during said removal of the needle from the receptacle whereby the second body remains in contact with the sealed receptacle as the guide member moves from its extended position to its retracted position during said insertion and from its retracted position to its extended position during said removal.
摘要翻译：针组件具有由第一主体支撑的至少一个引导构件，用于在延伸位置和缩回位置之间滑动。第二主体附接到引导构件。偏置构件将引导构件偏压到延伸位置。液体处理针联接到第一主体，使得引导构件朝向缩回位置的滑动运动使第二主体相对于液体处理针退回。第二主体适于接触密封的容器。偏置构件在插入期间以及在从插座中取出针时将引导构件推向所述延伸位置，由此当引导构件在插入期间从其延伸位置移动到其缩回位置时，第二主体与密封容器保持接触并且在所述移除期间从其缩回位置到其延伸位置。

4. 发明授权

US06939515B2 Apparatuses and methods for creating and testing pre-formulations and systems for same 失效
标题翻译：用于创建和测试预配制和相同系统的设备和方法
公开(公告)号：US06939515B2
公开(公告)日：2005-09-06
申请号：US10156245
申请日：2002-05-24
申请人： Eric D. Carlson , Peijun Cong , William H. Chandler, Jr. , Peter J. Desrosiers , J. Christopher Freitag , John F. Varni
发明人： Eric D. Carlson , Peijun Cong , William H. Chandler, Jr. , Peter J. Desrosiers , J. Christopher Freitag , John F. Varni
IPC分类号： G01N21/64 , B01J19/00 , B01L3/00 , B01L3/06 , B01L7/00 , C07B61/00 , C07D209/20 , C07D293/00 , C40B40/10 , C40B60/08 , C40B60/14 , G01N5/04 , G01N13/00 , G01N21/23 , G01N21/27 , G01N21/33 , G01N21/35 , G01N21/47 , G01N21/65 , G01N21/78 , G01N24/08 , G01N25/04 , G01N30/88 , G01N33/15 , G01N33/483 , G01N33/50 , G01N33/53 , G01N33/543 , G01N35/02 , G01N37/00 , B01L11/00
CPC分类号： B01L3/50255 , B01J19/0046 , B01J2219/00283 , B01J2219/00308 , B01J2219/00315 , B01J2219/00335 , B01J2219/00364 , B01J2219/00373 , B01J2219/00423 , B01J2219/00481 , B01J2219/00484 , B01J2219/00495 , B01J2219/00585 , B01J2219/00689 , B01J2219/00695 , B01J2219/00698 , B01J2219/00702 , B01J2219/00704 , B01J2219/00725 , B01J2219/00756 , B01L3/06 , B01L7/00 , B01L2300/0829 , B01L2300/185 , C40B40/04 , C40B40/10 , C40B60/10 , C40B60/14 , G01N5/045 , G01N21/23 , G01N21/65 , G01N25/04 , G01N33/15 , G01N33/54366 , G01N35/028 , G01N2013/006 , G01N2021/651 , G01N2500/00 , G06F19/703 , G06F19/709 , Y10T117/10
摘要： The invention provides methods, apparatus, and systems for performing high-throughput preparation and screening of salts and polymorphs of drug candidates. The invention is directed towards enhancing the pre-formulation discovery process used for drug development. In particular, processes that determine suitable salts and processes that discover substantially every polymorph that can form from a particular drug candidate are provided. The processes are performed using several apparatuses that are specifically configured to carry-out various steps in a high-throughput characterization process. One such apparatus is configured for synthesizing a plurality of library members based on, for example, a library model generated by a computer system. Another apparatus may filter the synthesized solution to provide a substantially pure mixture that can be subjected to salt or polymorph testing. Yet another apparatus may be used to crystallize mixtures on a substrate such that the crystallized mixture can be screened by one or more screening devices.
摘要翻译：本发明提供了用于进行候选药物的盐和多晶型物的高通量制备和筛选的方法，装置和系统。本发明旨在增强用于药物开发的预配制发现过程。特别地，提供了确定基本上发现可从特定药物候选物形成的每个多晶型物的合适的盐和方法的方法。使用特定配置为在高吞吐量表征过程中执行各种步骤的几个装置来执行处理。一种这样的装置被配置为基于例如由计算机系统生成的库模型来合成多个库成员。另一种装置可以过滤合成的溶液以提供可以进行盐或多晶型测试的基本上纯的混合物。可以使用另一种装置将混合物在基底上结晶，使得结晶的混合物可以被一个或多个筛选装置筛选。

5. 发明授权

US06679130B2 Instrument for high throughput measurement of material physical properties of a plurality of samples 失效
标题翻译：用于高通量测量多个样品的材料物理性质的仪器
公开(公告)号：US06679130B2
公开(公告)日：2004-01-20
申请号：US09779148
申请日：2001-02-08
申请人： Damian Hajduk , Eric Carlson , J. Christopher Freitag , Oleg Kosolov
发明人： Damian Hajduk , Eric Carlson , J. Christopher Freitag , Oleg Kosolov
IPC分类号： G01N300
CPC分类号： B01L3/5085 , B01J2219/00707 , B01J2219/00718 , G01N5/00 , G01N11/00 , G01N19/00 , G01N29/02 , G01N29/222 , G01N2203/0286 , G01N2291/02466 , G01N2291/0255 , G01N2291/02818 , G01N2291/106 , Y10T436/12
摘要： An apparatus and method for screening combinatorial libraries of materials by measuring the response of individual library members to mechanical perturbations is described. The apparatus generally includes a sample holder for containing the library members, an array of probes for mechanically perturbing individual library members, and an array of sensors for measuring the response of each of the library members to the mechanical perturbations. Library members undergoing screening make up a sample array, and individual library members constitute elements of the sample array that are confined to specific locations on the sample holder. During screening, the apparatus mechanically perturbs individual library members by displacing the sample array (sample holder) and the array of probes. Typically, all of the elements of the sample array are perturbed simultaneously, but the apparatus also can also perturb individual or groups of sample array elements sequentially. The flexible apparatus and method can screen libraries of materials based on many different bulk physical properties, including Young's modulus (flexure, uniaxial extension, biaxial compression, and shear); hardness (indentation), failure (stress and strain at failure, toughness), adhesion (tack, loop tack), and flow (viscosity, melt flow indexing, and rheology), among others.
摘要翻译：描述了通过测量单个文库成员对机械扰动的响应来筛选材料组合文库的装置和方法。该装置通常包括用于容纳库构件的样本保持器，用于机械扰乱各个库构件的探针阵列，以及用于测量每个库构件对机械扰动的响应的传感器阵列。正在进行筛选的图书馆成员组成一个样本数组，单独的图书馆成员构成了样本数组的元素，它们限于样本持有者的特定位置。在筛选期间，设备通过移位样品阵列（样品架）和探针阵列来机械地干扰各个库成员。通常，样本阵列的所有元素都被同时扰动，但是该装置也可以顺序扰乱单个或组的样本阵列元素。灵活的装置和方法可以基于许多不同的体积物理性质（包括杨氏模量（挠曲，单轴延伸，双轴压缩和剪切））筛选材料库; 硬度（压痕），破坏（破坏时的应力和应变，韧性），粘附性（粘性，环粘性）和流动性（粘度，熔体流动指数和流变学）等。

6. 发明授权

US06650102B2 High throughput mechanical property testing of materials libraries using a piezoelectric 失效
标题翻译：使用压电材料库的高通量力学性能测试
公开(公告)号：US06650102B2
公开(公告)日：2003-11-18
申请号：US09938994
申请日：2001-08-24
申请人： Damian A. Hajduk , Eric D. Carlson , J. Christopher Freitag , Oleg Kolosov , James R. Engstrom , Adam Safir , Ravi Srinivasan , Leonid Matsiev
发明人： Damian A. Hajduk , Eric D. Carlson , J. Christopher Freitag , Oleg Kolosov , James R. Engstrom , Adam Safir , Ravi Srinivasan , Leonid Matsiev
IPC分类号： G01N2700
CPC分类号： B01J19/0046 , B01J2219/00315 , B01J2219/00364 , B01J2219/00369 , B01J2219/00376 , B01J2219/00585 , B01J2219/00596 , B01J2219/00605 , B01J2219/0061 , B01J2219/00621 , B01J2219/00659 , B01J2219/00677 , B01J2219/00689 , B01J2219/00691 , B01J2219/00698 , B01J2219/00704 , B01J2219/00722 , B01J2219/00725 , B01J2219/00736 , B01J2219/00756 , G01N3/10 , G01N3/18 , G01N2203/0016 , G01N2203/0051 , G01N2203/0252 , G01N2203/0254 , G01N2203/0258 , G01N2203/0617 , G01N2203/0623 , G01N2203/0641
摘要： The present invention provides instruments and methods for screening combinatorial libraries that addresses many of the problems encountered when using conventional instruments. For example, the disclosed instruments can measure mechanical properties of library members in rapid serial or parallel test format, and can perform tests on small amounts of material, which are easily prepared or dispensed using art-disclosed liquid or solid handling techniques. Compared to conventional instruments, the disclosed instruments afford faster sample loading and unloading, for example, through the use of disposable libraries of material samples.
摘要翻译：本发明提供了用于筛选组合文库的仪器和方法，其解决了使用常规仪器时遇到的许多问题。例如，所公开的仪器可以以快速的串联或并行测试形式测量文库成员的机械性能，并且可以使用本领域公开的液体或固体处理技术容易地制备或分配的少量材料进行测试。与常规仪器相比，所公开的仪器例如通过使用材料样品的一次性库来提供更快的样品加载和卸载。

7. 发明授权

US06913934B2 Apparatus and methods for parallel processing of multiple reaction mixtures 有权
标题翻译：用于并行处理多种反应混合物的装置和方法
公开(公告)号：US06913934B2
公开(公告)日：2005-07-05
申请号：US10040988
申请日：2002-01-07
申请人： G. Cameron Dales , Gary Diamond , Trevor G. Frank , J. Christopher Freitag , Kenneth S. Higashihara , Dave Huffman , Jonah R. Troth
发明人： G. Cameron Dales , Gary Diamond , Trevor G. Frank , J. Christopher Freitag , Kenneth S. Higashihara , Dave Huffman , Jonah R. Troth
IPC分类号： B01J19/26 , B01F7/00 , B01F7/16 , B01F13/06 , B01F13/08 , B01F15/00 , B01J19/00 , B01L3/00 , B01L7/00 , B25J9/02 , C40B40/14 , C40B40/18 , C40B60/00 , C40B60/14 , F28F27/00 , G01K13/00 , G01N1/22 , G01N21/25 , G01N35/00 , G01N35/04 , G01N35/10 , G01N1/10 , B01L3/02
CPC分类号： B01F7/167 , B01F7/00258 , B01F7/00266 , B01F7/00291 , B01F7/00416 , B01F7/00575 , B01F13/065 , B01F13/08 , B01F15/00207 , B01F15/00357 , B01F15/00396 , B01F2215/0037 , B01J19/0006 , B01J19/0013 , B01J19/004 , B01J19/0046 , B01J2219/00029 , B01J2219/00162 , B01J2219/002 , B01J2219/00283 , B01J2219/00308 , B01J2219/0031 , B01J2219/00333 , B01J2219/00335 , B01J2219/00337 , B01J2219/00342 , B01J2219/00351 , B01J2219/00353 , B01J2219/00367 , B01J2219/00373 , B01J2219/00389 , B01J2219/00418 , B01J2219/00466 , B01J2219/00477 , B01J2219/00481 , B01J2219/00495 , B01J2219/00497 , B01J2219/00585 , B01J2219/0059 , B01J2219/00596 , B01J2219/00601 , B01J2219/00686 , B01J2219/00689 , B01J2219/00691 , B01J2219/00695 , B01J2219/00698 , B01J2219/00702 , B01J2219/00704 , B01J2219/0072 , B01J2219/00722 , B01J2219/00745 , B01L3/50851 , B01L3/50853 , B01L7/54 , B01L2200/026 , B01L2300/049 , B01L2300/06 , B01L2300/0627 , B01L2300/14 , B01L2300/1805 , C40B40/14 , C40B40/18 , C40B60/14 , F28F27/00 , G01K13/00 , G01N1/2226 , G01N21/253 , G01N35/0099 , G01N35/1004 , G01N35/1079 , G01N2035/00514 , G01N2035/0406 , Y10T436/2575
摘要： A cannula for use in transferring small volumes of fluid materials, such as in a parallel reaction process. The cannula comprises a long thin needle having various end (port) configurations, and an adapter for connecting the needle to a fluid line. The adapter may include the combination of a reservoir and transition, or simply a transition.
摘要翻译：用于转移少量流体材料的插管，例如在平行的反应过程中。套管包括具有各种端部（端口）构造的长细针，以及用于将针连接到流体管线的适配器。适配器可以包括储存器和转换器的组合，或简单地转换。

8. 发明授权

US06759014B2 Apparatus and methods for parallel processing of multiple reaction mixtures 有权
标题翻译：用于并行处理多种反应混合物的装置和方法
公开(公告)号：US06759014B2
公开(公告)日：2004-07-06
申请号：US09772101
申请日：2001-01-26
申请人： G. Cameron Dales , Jonah R. Troth , Kenneth S. Higashihara , Gary Diamond , Vince Murphy , William H. Chandler, Jr. , Trevor G. Frank , J. Christopher Freitag
发明人： G. Cameron Dales , Jonah R. Troth , Kenneth S. Higashihara , Gary Diamond , Vince Murphy , William H. Chandler, Jr. , Trevor G. Frank , J. Christopher Freitag
IPC分类号： B01J1900
CPC分类号： B01J19/0046 , B01J2219/00283 , B01J2219/00308 , B01J2219/00373 , B01J2219/00466 , B01J2219/00481 , B01J2219/00497 , B01J2219/00585 , B01J2219/00596 , B01J2219/00691 , B01J2219/00722 , C40B40/14 , C40B60/14 , G01N35/0099 , G01N35/1004 , G01N35/1079 , G01N2035/0406 , Y10T436/2575
摘要： A parallel reactor system including a reactor and vessels in the reactor for holding reaction mixtures, and a cannula for introducing fluid reaction material into the vessels. A robot system is operable to insert the cannula into cannula passages in the reactor for delivery of reaction materials, including slurries, to respective vessels, and to withdraw the cannula from the cannula passages after delivery. Related methods are also disclosed.
摘要翻译：一种并联反应器系统，包括用于保持反应混合物的反应器中的反应器和容器，以及用于将流体反应材料引入容器的插管。机器人系统可操作以将插管插入反应器中的插管通道中，用于将反应材料（包括浆料）输送到相应的容器，并且在输送后从插管通道中抽出套管。还公开了相关方法。

9. 发明授权

US06664067B1 Instrument for high throughput measurement of material physical properties and method of using same 失效
公开(公告)号：US06664067B1
公开(公告)日：2003-12-16
申请号：US09580024
申请日：2000-05-26
申请人： Damian Hajduk , Eric Carlson , J. Christopher Freitag , Oleg Kosolov
发明人： Damian Hajduk , Eric Carlson , J. Christopher Freitag , Oleg Kosolov
IPC分类号： G01D116
CPC分类号： B01L3/5085 , B01J2219/00707 , B01J2219/00718 , G01N5/00 , G01N11/00 , G01N19/00 , G01N29/02 , G01N29/222 , G01N2203/0286 , G01N2291/02466 , G01N2291/0255 , G01N2291/02818 , G01N2291/106 , Y10T436/12
摘要： An apparatus and method for screening combinatorial libraries of materials by measuring the response of individual library members to mechanical perturbations is described. The apparatus generally includes a sample holder for containing the library members, an array of probes for mechanically perturbing individual library members, and an array of sensors for measuring the response of each of the library members to the mechanical perturbations. Library members undergoing screening make up a sample array, and individual library members constitute elements of the sample array that are confined to specific locations on the sample holder. During screening, the apparatus mechanically perturbs individual library members by displacing the sample array (sample holder) and the array of probes. Typically, all of the elements of the sample array are perturbed simultaneously, but the apparatus also can also perturb individual or groups of sample array elements sequentially. The flexible apparatus and method can screen libraries of materials based on many different bulk physical properties, including Young's modulus (flexure, uniaxial extension, biaxial compression, and shear); hardness (indentation), failure (stress and strain at failure, toughness), adhesion (tack, loop tack), and flow (viscosity, melt flow indexing, and rheology), among others.

10. 发明授权

US07549978B2 Needle assembly 有权
标题翻译：针组装
公开(公告)号：US07549978B2
公开(公告)日：2009-06-23
申请号：US11131277
申请日：2005-05-16
申请人： Eric D. Carlson , Peijun Cong , William H. Chandler, Jr. , Peter J. Desrosiers , J. Christopher Freitag , John F. Varni
发明人： Eric D. Carlson , Peijun Cong , William H. Chandler, Jr. , Peter J. Desrosiers , J. Christopher Freitag , John F. Varni
IPC分类号： A61M5/31 , A61M5/00
CPC分类号： B01L3/50255 , B01J19/0046 , B01J2219/00283 , B01J2219/00308 , B01J2219/00315 , B01J2219/00335 , B01J2219/00364 , B01J2219/00373 , B01J2219/00423 , B01J2219/00481 , B01J2219/00484 , B01J2219/00495 , B01J2219/00585 , B01J2219/00689 , B01J2219/00695 , B01J2219/00698 , B01J2219/00702 , B01J2219/00704 , B01J2219/00725 , B01J2219/00756 , B01L3/06 , B01L7/00 , B01L2300/0829 , B01L2300/185 , C40B40/04 , C40B40/10 , C40B60/10 , C40B60/14 , G01N5/045 , G01N21/23 , G01N21/65 , G01N25/04 , G01N33/15 , G01N33/54366 , G01N35/028 , G01N2013/006 , G01N2021/651 , G01N2500/00 , G06F19/703 , G06F19/709 , Y10T117/10
摘要： A needle assembly has a first body and a guide rod supported for sliding movement between an extended position and a retracted position. A second body is attached to the guide rod. The second body is relatively farther from the first body when the guide rod is in the extended position and relatively closer to the first body when the guide rod is in the retracted position. The guide rod is biased to the extended position. The second body supports a venting needle that extends beyond the second body by a fixed length. A liquid handling needle is coupled to the first body. Sliding movement of the guide rod toward the retracted position retracts the second body and the venting needle relative to the liquid handling needle.
摘要翻译：针组件具有第一主体和支撑件，用于在延伸位置和缩回位置之间滑动。第二主体附接到导杆。当导杆处于缩回位置时，当导杆处于伸出位置并相对靠近第一主体时，第二主体相对较远离第一主体。引导杆偏置到伸出位置。第二主体支撑一个排气针，其延伸超过第二主体一个固定的长度。液体处理针联接到第一主体。引导杆朝向缩回位置的滑动运动使第二主体和排气针相对于液体处理针退回。

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