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1. 发明申请

US20120016462A1 Stent 审中-公开
标题翻译：支架
公开(公告)号：US20120016462A1
公开(公告)日：2012-01-19
申请号：US13243379
申请日：2011-09-23
申请人： Daniel Gregorich , Timothy S. Girton
发明人： Daniel Gregorich , Timothy S. Girton
IPC分类号： A61F2/82
CPC分类号： A61F2/915 , A61F2/91 , A61F2002/91508 , A61F2002/91516 , A61F2002/91525 , A61F2002/91533 , A61F2002/91558 , A61F2002/91566 , A61F2002/91575
摘要： A stent comprises a plurality of circumferential bands. Circumferential bands which are adjacent one another are connected one to the other. The circumferential bands include peaks and troughs interconnected by bent struts. The bands may overlap or may be connected by connectors.
摘要翻译：支架包括多个周向带。彼此相邻的环状带彼此连接。圆周带包括通过弯曲支柱互连的峰谷。带可以重叠或可以通过连接器连接。

2. 发明申请

US20090281615A1 STENT WITH TABS AND HOLES FOR DRUG DELIVERY 有权
标题翻译：具有用于药物递送的餐具和帽子
公开(公告)号：US20090281615A1
公开(公告)日：2009-11-12
申请号：US12117437
申请日：2008-05-08
申请人： Gordon J. Kocur , Daniel Gregorich , Timothy S. Girton
发明人： Gordon J. Kocur , Daniel Gregorich , Timothy S. Girton
IPC分类号： A61F2/82
CPC分类号： A61F2/915 , A61F2/91 , A61F2002/91558 , A61F2230/0054 , A61F2250/0068
摘要： A stent can include a tubular body, a plurality of circumferential serpentine bands, a plurality of connectors extending between immediately adjacent serpentine bands, and a plurality of tabs. The plurality of tabs include peak tabs and trough tabs. Each peak tab and each trough tab have a first end and a second end wherein only the first end is engaged to a serpentine band, each peak tab extends substantially parallel to the longitudinal axis from a peak on a serpentine band toward a peak on an immediately distal serpentine band. Each trough tab extends substantially parallel to the longitudinal axis from a trough on a serpentine band toward a trough on an immediately proximal serpentine band. Each serpentine band defines a plurality of holes and each tab defines a plurality of holes. The holes are constructed and arranged to contain a therapeutic agent
摘要翻译：支架可以包括管状体，多个圆周蛇形带，在紧邻的蛇形带之间延伸的多个连接器以及多个突片。多个突片包括峰片和槽片。每个峰突片和每个槽突片具有第一端和第二端，其中仅第一端接合到蛇形带，每个峰突片基本上平行于纵向轴线从蛇形带上的峰向立即远端蛇纹带。每个槽翼片从蛇形带上的槽基本上平行于纵向轴线延伸到在紧邻的蛇形带上的槽。每个蛇形带限定多个孔，每个翼片限定多个孔。孔被构造和布置成容纳治疗剂

3. 发明申请

US20100145437A1 Stent Design Allowing Extended Release of Drug and/or Enhanced Adhesion of Polymer to OD Surface 审中-公开
标题翻译：支架设计允许药物的扩展释放和/或增强的聚合物粘附到OD表面
公开(公告)号：US20100145437A1
公开(公告)日：2010-06-10
申请号：US12706881
申请日：2010-02-17
申请人： Timothy S. Girton , Jeffrey S. Lindquist , David M. Knapp , Matt Heidner , Daniel Gregorich , Umang Anand , Peter Edelman , Matthew J. Miller , Raed Rizq , Jan Weber , Tracee Eidenschink , John J. Chen , Jaykeep Y. Kokate , Aparna Bhave , Kent D. Harrison , Graig L. Kveen , Benjamin Arcand , Michael Kuchling
发明人： Timothy S. Girton , Jeffrey S. Lindquist , David M. Knapp , Matt Heidner , Daniel Gregorich , Umang Anand , Peter Edelman , Matthew J. Miller , Raed Rizq , Jan Weber , Tracee Eidenschink , John J. Chen , Jaykeep Y. Kokate , Aparna Bhave , Kent D. Harrison , Graig L. Kveen , Benjamin Arcand , Michael Kuchling
IPC分类号： A61F2/82
CPC分类号： A61F2/91 , A61F2210/0076 , A61F2220/0066 , A61F2220/0083 , A61F2250/0067 , A61F2250/0068
摘要： The invention is directed to mechanisms and methods that reduce the delamination of a therapeutic agent from a stent. The mechanisms include holes (channels, wells, and other hole configurations), protrusions, sintered metal cores, clamps/staples, pins, and stainless steel shields.
摘要翻译：本发明涉及减少治疗剂从支架分层的机制和方法。这些机构包括孔（通道，孔和其他孔构造），突起，烧结金属芯，夹/钉，销和不锈钢屏蔽。

4. 发明授权

US09827120B2 Stent 有权
公开(公告)号：US09827120B2
公开(公告)日：2017-11-28
申请号：US13243379
申请日：2011-09-23
申请人： Daniel Gregorich , Timothy S. Girton
发明人： Daniel Gregorich , Timothy S. Girton
IPC分类号： A61F2/82 , A61F2/915 , A61F2/91
CPC分类号： A61F2/915 , A61F2/91 , A61F2002/91508 , A61F2002/91516 , A61F2002/91525 , A61F2002/91533 , A61F2002/91558 , A61F2002/91566 , A61F2002/91575
摘要： A stent comprises a plurality of circumferential bands. Circumferential bands which are adjacent one another are connected one to the other. The circumferential bands include peaks and troughs interconnected by bent struts. The bands may overlap or may be connected by connectors.

5. 发明授权

US08070792B2 Stent 有权
标题翻译：支架
公开(公告)号：US08070792B2
公开(公告)日：2011-12-06
申请号：US10063179
申请日：2002-03-28
申请人： Daniel Gregorich , Timothy S. Girton
发明人： Daniel Gregorich , Timothy S. Girton
IPC分类号： A61F29/00 , A61M29/00
CPC分类号： A61F2/915 , A61F2/91 , A61F2002/91508 , A61F2002/91516 , A61F2002/91525 , A61F2002/91533 , A61F2002/91558 , A61F2002/91566 , A61F2002/91575
摘要： A stent comprises a plurality of circumferential bands. Circumferential bands which are adjacent one another are connected one to the other. The circumferential bands include peaks and troughs interconnected by bent struts. The bands may overlap or may be connected by connectors.
摘要翻译：支架包括多个周向带。彼此相邻的环状带彼此连接。圆周带包括通过弯曲支柱互连的峰谷。带可以重叠或可以通过连接器连接。

6. 发明申请

US20110066227A1 Stent with Dynamic Drug Reservoirs 审中-公开
标题翻译：动态药物支架支架
公开(公告)号：US20110066227A1
公开(公告)日：2011-03-17
申请号：US12561781
申请日：2009-09-17
申请人： Michael P. Meyer , Timothy S. Girton , Dennis Boismier , Daniel Gregorich , Kim Robertson , Liza Davis , Cory Hitzman , Samuel Robaina , Doug Thesingh
发明人： Michael P. Meyer , Timothy S. Girton , Dennis Boismier , Daniel Gregorich , Kim Robertson , Liza Davis , Cory Hitzman , Samuel Robaina , Doug Thesingh
IPC分类号： A61F2/06
CPC分类号： A61F2/915 , A61F2/90 , A61F2/91 , A61F2250/0035 , A61F2250/0068
摘要： A stent having one or more beneficial agents which enhance the healing effect of the stent. The agent is positioned within a reservoir. The reservoir dynamically releases the agent when the stent is expanded. The reservoir makes use of various changes in stent shape during expansion to assure proper release of the agent. Agent release can be modulated at various points along the stent and with various rates of release. The reservoirs can also be cooperatively combined with features that enhance stent flexibility, structural integrity, and which prevent recoil.
摘要翻译：具有增强支架愈合效果的一种或多种有益剂的支架。试剂位于储存器内。当支架扩张时，储层动态释放药剂。储存器在膨胀期间利用支架形状的各种变化，以确保试剂的适当释放。药剂释放可以在支架的各个点处以各种释放速率进行调节。储存器还可以与增强支架柔性，结构完整性以及防止反冲的特征协同结合。

7. 发明申请

US20090076591A1 Stent Design Allowing Extended Release of Drug and/or Enhanced Adhesion of Polymer to OD Surface 审中-公开
标题翻译：支架设计允许药物的扩展释放和/或增强的聚合物粘附到OD表面
公开(公告)号：US20090076591A1
公开(公告)日：2009-03-19
申请号：US11857736
申请日：2007-09-19
申请人： Timothy S. Girton , Jeffrey S. Lindquist , David M. Knapp , Matt Heidner , Daniel Gregorich , Umang Anand , Peter Edelman , Matthew J. Miller , Raed Rizq , Jan Weber , Tracee Eidenschink , John J. Chen , Jaykeep Y. Kokate , Aparna Bhave , Kent D. Harrison , Graig L. Kveen , Benjamin Arcand , Michael Kuehling
发明人： Timothy S. Girton , Jeffrey S. Lindquist , David M. Knapp , Matt Heidner , Daniel Gregorich , Umang Anand , Peter Edelman , Matthew J. Miller , Raed Rizq , Jan Weber , Tracee Eidenschink , John J. Chen , Jaykeep Y. Kokate , Aparna Bhave , Kent D. Harrison , Graig L. Kveen , Benjamin Arcand , Michael Kuehling
IPC分类号： A61F2/82
CPC分类号： A61F2/91 , A61F2210/0076 , A61F2220/0066 , A61F2220/0083 , A61F2250/0067 , A61F2250/0068
摘要： The invention is directed to mechanisms and methods that reduce the delamination of a therapeutic agent from a stent. The mechanisms include holes (channels, wells, and other hole configurations), protrusions, sintered metal cores, clamps/staples, pins, and stainless steel shields.
摘要翻译：本发明涉及减少治疗剂从支架分层的机制和方法。这些机构包括孔（通道，孔和其他孔构造），突起，烧结金属芯，夹/钉，销和不锈钢屏蔽。

8. 发明授权

US08641750B2 Stent design with sheath attachment members 失效
标题翻译：支架设计，带护套附件
公开(公告)号：US08641750B2
公开(公告)日：2014-02-04
申请号：US11857531
申请日：2007-09-19
申请人： Andrew D. Bicek , Timothy S. Girton
发明人： Andrew D. Bicek , Timothy S. Girton
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61F2/89 , A61F2/91 , A61F2/915 , A61F2002/075 , A61F2002/91525 , A61F2002/91533 , A61F2002/91575 , A61F2220/0016 , A61F2220/0075 , A61F2230/0054
摘要： A stent is provided having attachment members for allowing attachment of a sheath or sheaths. Accordingly, a practitioner is able to selectively choose a desirable sheath, such as a polymeric sleeve, a biomaterial, or a natural blood vessel, at a point-of-use and attach it to the sheath. The attachment members may be bendable tabs and/or secondary support stents.
摘要翻译：提供具有用于允许护套或护套附接的附接构件的支架。因此，从业者能够在使用点选择性地选择期望的护套，例如聚合物套管，生物材料或天然血管，并将其附着到护套上。附接构件可以是可弯曲的片和/或第二支撑支架。

9. 发明授权

US06666886B1 Tissue equivalent approach to a tissue-engineered cardiovascular valve 有权
标题翻译：组织工程心血管瓣膜的组织等效方法
公开(公告)号：US06666886B1
公开(公告)日：2003-12-23
申请号：US09505121
申请日：2000-02-16
申请人： Robert T. Tranquillo , Timothy S. Girton , Michael Neidert
发明人： Robert T. Tranquillo , Timothy S. Girton , Michael Neidert
IPC分类号： A61F206
CPC分类号： A61L27/3804 , A61F2/2415 , A61F2/2475 , A61L27/225 , A61L27/24 , A61L27/3843
摘要： The invention provides a molded valve leaflet containing a molded biopolymer having fibrils and cells within the molded biopolymer, wherein the fibrils of the molded biopolymer have commisure-to-commisure alignment. The invention also provides a valve equivalent containing a plurality of molded valve leaflets that are connected to a base, wherein the molded valve leaflets include a molded biopolymer having fibrils and cells within the molded biopolymer, wherein the fibrils of the molded biopolymer have commisure-to-commisure alignment.
摘要翻译：本发明提供了一种模制的瓣膜小叶，其包含在模制的生物聚合物内具有原纤维和细胞的模制生物聚合物，其中模制的生物聚合物的原纤维具有一致的连续对齐。本发明还提供了一种阀门等效物，其包含连接到基座的多个模制的瓣叶，其中模制的瓣叶包括在模制的生物聚合物中具有原纤维和细胞的模制生物聚合物，其中模制的生物聚合物的原纤维具有 - 对齐。

10. 发明授权

US08057534B2 Bioerodible endoprostheses and methods of making the same 有权
标题翻译：生物蚀刻内用假体及其制作方法
公开(公告)号：US08057534B2
公开(公告)日：2011-11-15
申请号：US11855516
申请日：2007-09-14
申请人： Dennis A. Boismier , Timothy S. Girton , Steven R. Larsen , Matt Shedlov , Ken Merdan , Barry O'Brien
发明人： Dennis A. Boismier , Timothy S. Girton , Steven R. Larsen , Matt Shedlov , Ken Merdan , Barry O'Brien
IPC分类号： A61F2/06
CPC分类号： A61F2/06 , A61F2/91 , A61F2002/30032 , A61F2002/30051 , A61F2002/30062 , A61F2002/3011 , A61F2210/0004 , A61F2210/0076 , A61F2230/0002 , A61F2250/003 , A61F2250/0054 , A61L31/022 , A61L31/08 , A61L31/148
摘要： A bioerodible endoprosthesis erodes to a desirable geometry that can provide, e.g., improved mechanical properties or degradation characteristics.
摘要翻译：生物腐蚀性内用假体侵蚀到可以提供例如改善的机械性能或降解特性的期望几何形状。

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