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    • 8. 发明申请
    • Portable preparation, analysis, and detection apparatus for nucleic acid processing
    • 用于核酸加工的便携式制备,分析和检测装置
    • US20070141605A1
    • 2007-06-21
    • US11602149
    • 2006-11-20
    • Charles VannMichael GreensteinYuh-Min Chiang
    • Charles VannMichael GreensteinYuh-Min Chiang
    • C12Q1/68C12M3/00
    • G01N27/447C12M47/06C12Q1/6806C12Q1/686
    • The present teachings comprise a device and method for lysing and/or purifying biological sample. The device can comprise a cartridge having a chamber containing a biological sample receiving region, a plurality of electrodes, and one or more sieving matrices. The electrodes can be configured to lyse the biological sample through the production of a pulsed electrical field. The electrodes can also be configured to heat lyse the biological sample. The electrodes can also be configured to electrophoretically move the biological sample through one or more sieving matrices. A portion of the sample can be isolated on a membrane. The portion of the sample isolated on the membrane can be amplified and detected. A portion of the sample can be isolated in a collection area present in the cartridge. The portion of the sample isolated in the collection area can be removed from the cartridge.
    • 本教导包括用于裂解和/或纯化生物样品的装置和方法。 该装置可以包括具有包含生物样品接收区域,多个电极和一个或多个筛分基质的腔室的药筒。 电极可以被配置成通过产生脉冲电场来裂解生物样品。 电极也可以被配置为热裂解生物样品。 电极还可以被配置成通过一个或多个筛分基质电泳移动生物样品。 样品的一部分可以在膜上分离。 可以扩增和检测在膜上分离的样品的部分。 样品的一部分可以在存在于盒中的收集区域中分离。 分离在收集区域中的样品的部分可以从盒中取出。