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    • 3. 发明申请
    • APPARATUS AND METHOD FOR CONTINUOUS PRODUCTION OF MATERIALS
    • 用于连续生产材料的装置和方法
    • US20120001356A1
    • 2012-01-05
    • US13158142
    • 2011-06-10
    • Chih-hung ChangHyungdae Jin
    • Chih-hung ChangHyungdae Jin
    • B29B9/00B01J19/00B82Y40/00B82Y99/00
    • B01J19/0093B01J2219/00788B01J2219/00795B01J2219/00849B01J2219/0086B01J2219/00873B01J2219/00889B01J2219/00894B82Y30/00B82Y40/00
    • Embodiments of a continuous-flow injection reactor and a method for continuous material synthesis are disclosed. The reactor includes a mixing zone unit and a residence time unit removably coupled to the mixing zone unit. The mixing zone unit includes at least one top inlet, a side inlet, and a bottom inlet. An injection tube, or plurality of injection tubes, is inserted through the top inlet and extends past the side inlet while terminating above the bottom outlet. A first reactant solution flows in through the side inlet, and a second reactant solution flows in through the injection tube(s). With reference to nanoparticle synthesis, the reactant solutions combine in a mixing zone and form nucleated nanoparticles. The nucleated nanoparticles flow through the residence time unit. The residence time unit may be a single conduit, or it may include an outer housing and a plurality of inner tubes within the outer housing.
    • 公开了连续流动注射反应器的实施例和连续材料合成的方法。 反应器包括混合区单元和可移除地耦合到混合区单元的停留时间单元。 混合区单元包括至少一个顶部入口,侧部入口和底部入口。 注射管或多个注射管通过顶部入口插入并延伸通过侧入口,同时终止在底部出口上方。 第一反应物溶液通过侧入口流入,并且第二反应物溶液流过注射管。 关于纳米颗粒合成,反应物溶液在混合区中结合并形成有核的纳米颗粒。 有核的纳米颗粒流过停留时间单位。 停留时间单元可以是单个导管,或者它可以包括在外壳内的外壳和多个内管。
    • 4. 发明申请
    • Microfluidic devices, particularly filtration devices comprising polymeric membranes, and method for their manufacture and use
    • 微流体装置,特别是包括聚合物膜的过滤装置及其制造和使用的方法
    • US20110253629A1
    • 2011-10-20
    • US13068037
    • 2011-04-29
    • Goran JovanovicSundar V. AtreBrian Kevin PaulJohn SimonsenVincent Thomas RemchoChih-Hung Chang
    • Goran JovanovicSundar V. AtreBrian Kevin PaulJohn SimonsenVincent Thomas RemchoChih-Hung Chang
    • B01D61/24B01D35/18
    • B01D61/18A61M1/16A61M1/1698A61M1/3472A61M2205/3334A61M2205/3368A61M2205/50B01D63/08B01D63/088B01D71/10B01D71/68B01D2313/21B01D2313/38
    • The present disclosure describes devices useful for microscale fluid purification, separation, and synthesis devices. Generally, such devices comprise a fluid membrane that separates two or more fluids flowing through plural microchannels operatively associated with the membrane. The fluids can both be liquids, gases, or a liquid and a gas, such as may be used for gas absorption into a liquid. Often, the membrane is a semipermeable membrane, such as might be used with a filtration device, such as a dialyzer. Devices of the present invention can be combined with other microscale devices to make systems. For example, the devices may be coupled with one or more microchemical microfactories, one or more micromixers, one or more microheaters; etc. Examples of devices made according to the present invention included an oxygenator, a dialzyer, microheat exchangers, etc. Particular materials had to be developed for use with certain embodiments of the device disclosed herein. For example, a new composite material was made comprising nanocrystalline cellulose filler and a polysulfone polymeric material. A dialyzer comprising the composite membrane also is disclosed. In order to make the nanocrystalline cellulose-polymer composite, a new method was devised for making an organic dispersion of nanocrystalline cellulose. The method comprised first forming an aqueous dispersion of nanocrystalline cellulose. A mixture was then formed comprising the aqueous dispersion and an organic liquid having a boiling point higher than water. The water was then selectively removed to form a second mixture comprising the nanocrystalline cellulose and the organic liquid.
    • 本公开描述了可用于微量流体纯化,分离和合成装置的装置。 通常,这样的装置包括流体膜,其分离流过与膜操作性相关联的多个微通道的两个或更多个流体。 流体可以是液体,气体或液体和气体,例如可以用于气体吸收到液体中。 通常,膜是半透膜,例如可以与过滤装置如透析器一起使用。 本发明的装置可以与其他微型装置组合以制造系统。 例如,所述装置可以与一个或多个微化学微生物,一个或多个微混合器,一个或多个微加热器结合; 根据本发明制造的装置的实例包括氧合器,拨动器,微热交换器等。必须开发特定的材料以用于本文公开的装置的某些实施例。 例如,制备了包含纳米晶纤维素填料和聚砜聚合物材料的新型复合材料。 还公开了包含复合膜的透析器。 为了制备纳米晶纤维素 - 聚合物复合材料,设计了一种制备纳米晶纤维素有机分散体的新方法。 该方法首先形成纳米晶体纤维素的水性分散体。 然后形成包含水分散体和沸点高于水的有机液体的混合物。 然后选择性地除去水以形成包含纳米晶体纤维素和有机液体的第二混合物。