专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2023090890A1 대사체 분류 및 분석을 위한 유전이동 기반 다이나믹 SERS 나노소자 审中-公开
公开(公告)号：WO2023090890A1
公开(公告)日：2023-05-25
申请号：PCT/KR2022/018187
申请日：2022-11-17
申请人： 한국과학기술원 , 사회복지법인 삼성생명공익재단
发明人： 정연식 , 김민준 , 구민재 , 조승희 , 박형준 , 이민영
IPC分类号： G01N21/65 , G01N21/66 , G01N33/483 , G01J3/44 , B82Y15/00 , B82Y40/00
摘要： 대사체 분류 및 분석을 위한 유전이동 기반 다이나믹 SERS 나노소자가 제시된다. 본 발명의 일 실시예에 따른 유전이동 기반 다이나믹 SERS(Surface-Enhanced Raman Spectroscopy) 나노소자를 이용한 대사체 분석 방법은, 표면 영역이 어레이 형태로 이루어진 다이나믹 SERS 나노소자를 준비하는 단계; 상기 다이나믹 SERS 나노소자에 전압을 인가하는 단계; 및 전압 인가에 따라 상기 다이나믹 SERS 나노소자의 극성을 제어하여 분석 대상의 대사체들이 영역별로 분류되는 단계를 포함하여 이루어질 수 있다.

2. 发明申请

WO2023082021A1 MAGNETIC MICROGEL BEADS, METHODS OF MAKING AND USES THEREOF 审中-公开
公开(公告)号：WO2023082021A1
公开(公告)日：2023-05-19
申请号：PCT/CA2022/051679
申请日：2022-11-14
申请人： MCMASTER UNIVERSITY
发明人： SOLEYMANI, Leyla , HOARE, Todd , LI, Yingfu , LU, Yang , PANDEY, Richa
IPC分类号： G01N33/553 , C12Q1/68 , G01N33/531 , G01N21/66 , G01N21/76 , G01N27/416
摘要： This disclosure relates to magnetic microgel beads, and in particular to magnetic microgel beads for biofunctionalization and methods of making and uses thereof, for example, in biosensing assays. In an embodiment, a magnetic microparticle comprising a magnetic nanoparticle encapsulated by a polymer hydrogel. In another embodiment, an assay for detecting the presence of a target analyte in a sample comprising a) the magnetic microparticle disclosed herein, wherein the biorecognition agent further comprises a reporter moiety; b) an electrochemical chip comprising a working electrode, a counter electrode and a reference electrode; and c) a capture probe functionalized on the working electrode; wherein binding of the biorecognition agent to the target analyte results in production of an electrochemical, electroluminescent or photoelectrochemical signal.

3. 发明申请

WO2021084472A1 METHOD OF IMPROVING ELECTROCHEMILUMINESCENCE SIGNAL IN BIOANALYTICAL ASSAYS 审中-公开
公开(公告)号：WO2021084472A1
公开(公告)日：2021-05-06
申请号：PCT/IB2020/060163
申请日：2020-10-29
申请人： RUBIPY SCIENTIFIC INC.
发明人： ZHOU, Ming
IPC分类号： C09K11/06 , C07D213/24 , C07D221/12 , C07D401/12 , C07D471/04 , G01N21/66 , G01N21/76 , G01N33/53 , G01N33/577 , G01N33/58
摘要： Electrochemiluminescence (ECL) lable molecules, detection reagents labled with the ECL label molecules, and methods of using the ECL label molecules and detection reagents labeled with the ECL label molecules for bioanalytical assays, especially immunoassays and nucleic acid assays using electrogenerated chemiluminescence or electrochemiluminescence (ECL) of delocalized luminophores, are disclosed.

4. 发明申请

WO2021011630A1 ASSAY APPARATUSES, METHODS AND REAGENTS 审中-公开
公开(公告)号：WO2021011630A1
公开(公告)日：2021-01-21
申请号：PCT/US2020/042104
申请日：2020-07-15
申请人： MESO SCALE TECHNOLOGIES, LLC.
发明人： KRIVOY, Gary I. , ZIMMERMAN, Cecilia , VANDERSARL, Jules , KOVACS, Sandor , LEIMKUEHLER, Aaron H. , TABAKIN, Leo , WILLOUGHBY, Jon , KOCHAR, Manish , CLINTON, Charles M.
IPC分类号： B01L3/00 , B01L7/00 , G01N21/03 , G01N21/66 , G01N21/76
摘要： Apparatuses, systems, method, reagents, and kits for conducting assays as well as process for their preparation are described. The apparatuses, systems, method, reagents, and kits may be employed in conducting automated analysis in a multi-well plate assay format.

5. 发明申请

WO2020151804A1 SULFONATED 2(7)-AMINOACRIDONE AND 1-AMINOPYRENE DYES AND THEIR USE AS FLUORESCENT TAGS, IN PARTICULAR FOR CARBOHYDRATE ANALYSIS 审中-公开
公开(公告)号：WO2020151804A1
公开(公告)日：2020-07-30
申请号：PCT/EP2019/051396
申请日：2019-01-21
申请人： MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSCHAFTEN E. V.
发明人： HELL, Stefan W. , BELOV, Vladimir , BISCHOFF, Matthias , MEINEKE, Dirk , THOMAS, Laura , MITRONOVA, Gyuzel , SAVICHEVA, Elizaveta , KOLMAKOV, Kirill , BÖHM, Marvin J. , RAPP, Erdmann , HENNIG, René
IPC分类号： C09B57/00 , G01N21/66 , G01N33/58 , A61K49/00 , C07C311/16 , C07D219/08
摘要： Sulfonated 2(7)-aminoacridone and 1-aminopyrene dyes and their use as fluorescent tags, in particular for carbohydrate analysis The invention relates to fluorescent dyes with multiple negatively charged groups in their ionized form which are aminoacridone sulfonamides or 1-aminopyrenes having of one of the following general formulae A-D: Formula (A), Formula (B), Formula (C), Formula (D), wherein the ionizable groups X are typically selected from the following: SH, COOH, SO 3 H, OSO 3 H, OP(O)(OH) 2 , OP(O)(OH)R a , P(O)(OH) 2 , P(O)(OH)R a , where R a = C 1 -C 4 alkyl or substituted C 1 -C 4 alkyl. The invention further relates to the use of these dyes as fluorescent tags, in particular for reducing sugars and glycans.

6. 发明申请

WO2019002698A1 A METHOD AND A DEVICE FOR DYNAMIC GENERATION OF HOT ELECTRONS INTO AQUEOUS SOLUTIONS 审中-公开
公开(公告)号：WO2019002698A1
公开(公告)日：2019-01-03
申请号：PCT/FI2018/050523
申请日：2018-06-29
申请人： LABMASTER OY , BIOMETRO CO LTD.
发明人： PAVLOV, Andrei , KORPELA, Timo , WAHLROOS, Tony
IPC分类号： G01N21/66 , G01N21/76
CPC分类号： G01N21/66 , G01N21/76
摘要： A device for generating a homogeneous flux of hot electrons in an aqueous solution comprises a cathode electrode (52) and first and second control electrodes (53, 54) on a substrate (51) surface, an anode electrode (57), a resistive barrier layer (55) on the cathode electrode, an isolation layer (61) between the control electrodes and the anode electrode, and an aqueous sensing layer (56) above the barrier layer, all said electrodes being connected to electronic circuitry, the control electrodes creating a lateral electro-static field and the anode electrode creating a vertical electro-magnetic field across the barrier layer, wherein hot electrons are generated by electric cathodic pulses, the hot electrons gain kinetic energy by moving laterally in the lateral electrostatic-field, and the lateral movement is changed to a vertical movement by cathodic voltage pulses providing change of lateral momentum of an electron to vertical momentum, whereby hot electrons with sufficient energy tunnel the barrier layer.

7. 发明申请

WO2016145539A1 ELECTROCHEMICAL FLOW CELL AND ULTRAMICROELECTRODE 审中-公开
标题翻译：电化学流化床和超微电子
公开(公告)号：WO2016145539A1
公开(公告)日：2016-09-22
申请号：PCT/CA2016/050314
申请日：2016-03-18
申请人： THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY
发明人： MAUZEROLL, Janine , DANIS, Laurence , NOYHOUZER, Tomer Aharon , SNOWDEN, Michael Edward , TEFASHE, Ushula Mengesha
IPC分类号： G01N27/30 , G01N21/66 , G01N21/76 , G01N27/36 , G01N27/403
CPC分类号： G01N21/66 , G01N27/416
摘要： An electrochemical flow cell is described which includes a flow passage extending between the inlet and outlet to define a flow path for fluid to flow through the cell body as fully developed laminar flow. A number of flow-through electrodes are disposed within the flow passage. The flow-through electrodes are arranged in serial flow succession within the flow passage and have a plurality of apertures therein through which the fluid passes. The working electrode is positioned within the flow passage at a predetermined distance downstream of the inlet of the cell body which corresponds to a streamwise location at which substantially fully developed laminar flow occurs. At least the working electrode of the flow cell may comprise an ultramicroelectrode that is manufactured as described herein. However, this ultramicroelectrode, whether single or multicore, may also be used for applications other than the described flow cell.
摘要翻译：描述了一种电化学流动池，其包括在入口和出口之间延伸的流动通道，以限定用于流体以充分发展的层流流动通过电池体的流动路径。多个流通电极设置在流路内。流通电极在流动通道内连续地串联布置，并且在其中具有多个孔，流体通过该孔。工作电极定位在流动通道内，在电池体入口下游一预定距离处，对应于发生基本上完全发展的层流的流动位置。至少流动池的工作电极可以包括如本文所述制造的超微电极。然而，这种超微电极（无论是单孔还是多芯）也可以用于除了所描述的流动池之外的应用。

8. 发明申请

WO2014161983A1 PROCEDE ET SYSTEME DE CONTROLE DE LA QUALITE D'UN DISPOSITIF PHOTOVOLTAIQUE 审中-公开
标题翻译：用于控制光伏器件质量的方法和系统
公开(公告)号：WO2014161983A1
公开(公告)日：2014-10-09
申请号：PCT/EP2014/056800
申请日：2014-04-04
申请人： COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES
发明人： MABILLE, Loïc
IPC分类号： G01N21/95 , G01R31/26 , G01N21/66
CPC分类号： H02S50/15 , G01N21/66 , G01N21/9505 , H02S50/10
摘要： Le dispositif photovoltaïque comprend une cellule photovoltaïque (1 ) assemblée à un substrat (2) par l'intermédiaire d'une interface d'assemblage. Le procédé comprend une étape d'injection d'un courant électrique à travers la cellule photovoltaïque et une étape d'acquisition d'un signal de mesure de radiations lumineuses émises par la cellule photovoltaïque (1 ), par électroluminescence, en réponse au courant injecté. Le courant d'injection a une densité supérieure à un seuil de courant prédéfini de détection de défauts d'assemblage. Il est prévu une étape de détection d'au moins un défaut dans l'interface d'assemblage à partir dudit signal de mesure acquis.
摘要翻译：光伏器件包括通过组装接口组装到衬底（2）的光伏电池（1）。该方法包括：通过光伏电池注入电流的步骤，以及通过电致发光响应于注入的电流获取由光伏电池（1）发射的光辐射的测量信号的步骤。注入电流的密度大于用于检测组件故障的预定电流阈值。该方法包括从所述获取的测量信号中检测组装接口中的至少一个故障的步骤。

9. 发明申请

WO2014147234A1 VERFAHREN UND VORRICHTUNG ZUR BESTIMMUNG VON MATERIALPARAMETERN, INSBESONDERE DER LADUNGSTRÄGERLEBENSDAUER EINES HALBLEITERSUBSTRATES DURCH MESSUNG VON LUMINESZENZSTRAHLUNG 审中-公开
标题翻译：方法和装置用于测定材料参数，通过测定发光的半导体衬底尤其是承载器LIFE
公开(公告)号：WO2014147234A1
公开(公告)日：2014-09-25
申请号：PCT/EP2014/055728
申请日：2014-03-21
申请人： FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E.V.
发明人： GIESECKE, Johannes , WARTA, Wilhelm , SCHUBERT, Martin
IPC分类号： G01R31/26 , G01N21/66
CPC分类号： G01N21/66 , G01R31/2648 , H01L22/12
摘要： Die Erfindung betrifft ein Verfahren zur Bestimmung von Materialparametern, insbesondere der Ladungsträgerlebensdauer eines Haibleitersubstrates durch Messung von Lumineszenzstrahlung, folgende Verfahrensschritte umfassend: a. Anregen des Halbleitersubstrats zum Erzeugen von Lumineszenzstrahlung durch injizieren von Ladungsträgern in dem Halbleitersubstrat, wobei der zeitliche Verlauf der Anregungsintensität l A (t) periodisch moduliert ist; b. Zeitaufgelöstes Messen der Intensität der von einem Messbereich des Haibleitersubstrates ausgehenden Lumineszenzstrahlung, wobei zumindest der relative zeitliche Verlauf der Lumineszenzstrahlung Ø(t) zumindest während einer Anregungsperiode gemessen wird; c. Bestimmen mindestens eines Materialparameters des Haibleitersubstrates abhängig von dem zeitlichen Verlauf der Anregungsintensität l A (t) und dem zeitlichen Verlauf der Intensität der Lumineszenzstrahlung ∅(t) ; Die Erfindung ist dadurch gekennzeichnet, dass in Verfahrensschritt A eine Strom-Spannungsquelle elektrisch leitend mit dem Halbleitersubstrat verbunden wird und mittels der Strom-Spannungsquelle das Anregen mittels Beaufschlagen des Haibleitersubstrates mit zeitlich modulierter elektrischer Spannung erfolgt.
摘要翻译：本发明涉及一种用于通过发光测量来确定材料的参数，特别是Haibleitersubstrates的充电载流子寿命，其包括以下步骤：a。激发半导体衬底注入载流子到半导体衬底，其中所述激发强度（t）的时间分布被调制周期性地升A到产生发光; 湾从Haibleitersubstrates发光辐射的测量范围的发出，其中至少发光O（T）的相对时间进程期间的激励期间至少测量的强度的时间分辨测量; 温度。确定取决于激发强度I A（t）和发光辐射∅（t）的强度的时间变化曲线的时间分布的材料Haibleitersubstrates中的至少一个参数; 本发明的特征在于，一个电流 - 电压源导电地连接到在方法步骤A中的半导体基板，以及由所述电流 - 电压源的装置，所述激励装置激励以在时间上调制电电压的Haibleitersubstrates。

10. 发明申请

WO2013173524A9 CLINICAL DIAGNOSTIC SYSTEM INCLUDING INSTRUMENT AND CARTRIDGE 审中-公开
标题翻译：临床诊断系统包括仪器和培养皿
公开(公告)号：WO2013173524A9
公开(公告)日：2014-01-09
申请号：PCT/US2013041252
申请日：2013-05-15
申请人： WELLSTAT DIAGNOSTICS LLC
发明人： COOK RICHARD ALAN , CHO SANG , DAVIS CHARLES QUENTIN , DORSEY KEVIN E , HARLEY JASON CHARLES , LELAND JONATHAN , MATIKYAN ROBER KRIKOR , OTTEN SJEF , PETERMAN JEFFREY HOWARD , THOMAS BRIAN B
IPC分类号： G01N21/66 , F04B49/06 , F04B49/10 , H05B1/02
CPC分类号： B01L3/527 , B01L2200/10 , B01L2200/16 , B01L2300/042 , B01L2300/0861 , B01L2300/105 , B65B1/04 , B65B3/04 , B65B5/04 , B65B55/00 , F04B49/065 , F04B49/106 , G01N21/66 , G01N27/3273 , G01N33/50 , G01N33/536 , G01N33/543 , G01N33/58 , G01N33/582 , G01N35/1079 , H05B1/025 , Y10T436/25 , Y10T436/2575
摘要： In embodiments disclosed herein, a diagnostic system is provided having a cartridge comprising at least one needle; at least one reservoir; at least one fluidic seal; and at least one fluidic channel of a fluidic pathway, wherein the cartridge is configured to store at least one reagent and at least one waste material on the cartridge. The diagnostic system is provided also having a diagnostic instrument comprising the fluidic pathway; an electrochemiluminescence (ECL) detection system; and a pump, wherein the fluidic pathway begins and ends in the cartridge and has a substantially single direction of flow in a pathway fluidically connecting the diagnostic instrument and the cartridge.
摘要翻译：在本文公开的实施例中，提供了一种诊断系统，其具有包含至少一根针的药筒; 至少一个储存器; 至少一个流体密封件; 以及流体路径的至少一个流体通道，其中所述筒构造成在所述筒上存储至少一种试剂和至少一种废料。提供的诊断系统还具有包含流体路径的诊断仪器; 电化学发光（ECL）检测系统; 以及泵，其中所述流体路径在所述筒中开始和结束，并且在流体连接所述诊断仪器和所述筒的路径中具有基本单一的流动方向。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式