会员体验
专利管家(专利管理)
工作空间(专利管理)
风险监控(情报监控)
数据分析(专利分析)
侵权分析(诉讼无效)
联系我们
交流群
官方交流:
QQ群: 891211   
微信请扫码    >>>
现在联系顾问~
热词
    • 6. 发明申请
    • IMPROVED PROCESS FOR ANALYZING, FOR SEPARATING, AND FOR ISOLATING INDIVIDUAL POLAR PROTIC MONOMERS AND/OR OLIGOMERS
    • 用于分析,分离和分离个体极地影响单体和/或低聚物的改进方法
    • WO2007041510A1
    • 2007-04-12
    • PCT/US2006/038478
    • 2006-10-03
    • MARS, INCORPORATEDKELM, Mark, A.JOHNSON, Christopher, J.ROBBINS, Rebecca, J.
    • KELM, Mark, A.JOHNSON, Christopher, J.ROBBINS, Rebecca, J.
    • B01D15/08
    • B01D15/32B01J20/286B01J20/288B01J2220/54
    • A process for separating and isolating individual polar protic monomer(s) and/or oligomer(s) on the basis of degree of polymerization is disclosed. A liquid sample containing monomer(s) and/or oligomer(s) is introduced into a liquid chromatography (LC) column packed with a polar bonded stationary chromatographic phase. The individual monomer(s) and/or oligomer(s) are separated via a binary mobile phase elution. The monomer(s) and/or oligomer(s) may be proanthocyanidins, hydrolyzable tannins, oligosaccharides, oligonucleotides, peptides, acrylamides, polysorbates, polyketides, poloxamers, polyethylene glycols, polyoxyethylene alcohols, or polyvinyl alcohols. The binary mobile phase comprises an A phase consisting essentially of a polar aprotic solvent and a B phase consisting essentially of a polar protic solvent. A process for separating and isolating xanthine(s) e.g., caffeine and theobromine is also disclosed. A liquid sample containing xanthine(s) and the monomer(s) and/or oligomer(s) is introduced into an LC column packed with a polar bonded stationary chromatographic phase. The xanthines are separated via an isocratic mobile phase elution and the individual fraction(s) are eluted. A process for separating and isolating the xanthines as well as polar protic monomer(s) and/or oligomer(s) is also disclosed. The phases discussed above are used in this rocess.
    • 公开了基于聚合度分离和分离各极性质子单体和/或低聚物的方法。 将含有单体和/或低聚物的液体样品引入装有极性键合静止色谱相的液相色谱(LC)柱中。 各个单体和/或低聚物通过二元流动相洗脱分离。 单体和/或低聚物可以是原花青素,可水解的单宁,寡糖,寡核苷酸,肽,丙烯酰胺,聚山梨酯,聚酮化合物,泊洛沙姆,聚乙二醇,聚氧乙烯醇或聚乙烯醇。 二元流动相包含基本上由极性非质子溶剂和基本上由极性质子溶剂组成的B相组成的A相。 还公开了分离和分离黄嘌呤(例如咖啡因和可可碱)的方法。 将含有黄嘌呤和单体和/或低聚物的液体样品引入填充有极性键合静止色谱相的LC柱中。 黄嘌呤通过等度流动相洗脱分离,各个级分被洗脱。 还公开了分离和分离黄嘌呤以及极性质子单体和/或低聚物的方法。 上述阶段在这个过程中被使用。