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1. 发明申请

WO2015164473A1 THERAPY DELIVERY CIRCUITS FOR AN IMPLANTABLE MEDICAL DEVICE 审中-公开
标题翻译：用于可植入医疗器械的治疗电路
公开(公告)号：WO2015164473A1
公开(公告)日：2015-10-29
申请号：PCT/US2015/027035
申请日：2015-04-22
申请人： MEDTRONIC, INC.
发明人： CRUTCHFIELD, Randolph, E. , CABELKA, Lonny, V. , BOONE, Mark, R. , KUEHN, Kevin, P. , RASMUSSEN, Marshall, J.
IPC分类号： A61N1/36 , A61N1/362 , A61N1/37 , A61N1/39
CPC分类号： A61N1/385 , A61N1/0587 , A61N1/362 , A61N1/3706 , A61N1/3912 , A61N1/3925 , A61N1/3956 , A61N1/3962 , A61N1/3975
摘要： Apparatus for generating an induction waveform for performing threshold testing in an implantable medical device are disclosed. Such tests may be performed during the implant procedure, or during a device checkup procedure, or routinely during the lifetime of the device. The threshold test may include induction of an arrhythmia (such as ventricular fibrillation) followed by delivery of therapy at various progressively-increasing stimulation parameters to terminate the arrhythmia. As such, the capability to induce fibrillation within the device is desired. Induction of the arrhythmias may be accomplished via delivery of a relatively low energy shock or through delivery of an induction stimulation pulse to the cardiac tissue timed concurrently with the vulnerable period of the cardiac cycle.
摘要翻译：公开了一种用于在可植入医疗装置中产生用于进行阈值测试的感应波形的装置。这样的测试可以在植入过程期间，或者在设备检查过程期间，或者在设备的寿命期间常规地执行。阈值测试可以包括诱导心律失常（例如心室颤动），随后以各种逐渐增加的刺激参数递送治疗以终止心律失常。因此，期望在装置内诱导原纤维化的能力。心律不齐的诱导可以通过递送相对低的能量冲击或通过将感应刺激脉冲递送到与心动周期的脆弱时段同时定时的心脏组织来实现。

2. 发明申请

WO2015164442A1 THERAPY DELIVERY CIRCUITS FOR AN IMPLANTABLE MEDICAL DEVICE 审中-公开
标题翻译：用于可植入医疗器械的治疗电路
公开(公告)号：WO2015164442A1
公开(公告)日：2015-10-29
申请号：PCT/US2015/026974
申请日：2015-04-22
申请人： MEDTRONIC, INC.
发明人： CRUTCHFIELD, Randolph E. , CABELKA, Lonny V.
IPC分类号： A61N1/36 , A61N1/362 , A61N1/37 , A61N1/39
CPC分类号： A61N1/3925 , A61N1/36125 , A61N1/362 , A61N1/3706 , A61N1/385 , A61N1/3906 , A61N1/3912 , A61N1/3956 , A61N1/3975
摘要： Techniques are disclosed for modulating the generation of charge current by operational circuitry included in an implantable medical device (IMD) for delivery of an induction stimulation pulse waveform by the IMD. The modulation may include modulating a charging circuit of the operational circuitry to facilitate the regulation of the induction stimulation pulse waveform. The techniques include monitoring an electrical parameter of a charging path during the delivery of the induction stimulation pulse and modulating the charging circuit based on the monitored electrical parameter.
摘要翻译：公开了用于通过包括在用于由IMD传送感应刺激脉冲波形的可植入医疗装置（IMD）中的操作电路来调制充电电流的产生的技术。调制可以包括调制操作电路的充电电路以便于调节感应刺激脉冲波形。这些技术包括在传送感应刺激脉冲期间监测充电路径的电参数，并且基于所监视的电参数调制充电电路。

3. 发明申请

WO2013107546A2 RELAIS FÜR EINEN DEFIBRILLATOR 审中-公开
标题翻译：继电器除颤器
公开(公告)号：WO2013107546A2
公开(公告)日：2013-07-25
申请号：PCT/EP2012/073571
申请日：2012-11-26
申请人： METRAX GMBH
IPC分类号： H01H50/00
CPC分类号： H01H50/643 , A61N1/39 , A61N1/3912 , A61N1/3968 , H01H50/24 , H01H50/30 , H01H50/58 , H01H50/60
摘要： Die Erfindung bezieht sich auf ein Relais für einen Defibrillator mit einer Tragebasis (50), auf der eine Spule (40) und eine durch deren elektrische Erregung über einen Anker (30) und mindestens ein weiteres mechanisches Zwischenglied betätigbare Kontaktiereinheit (10) mit einer Kontaktanordnung montiert sind, welche an Kontaktträgern (12, 13, 14) getragene Kontakte (11, 11') aufweist, die durch Ansteuerung der Spule (40) miteinander in Verbindung bringbar sind. Um die Kontaktierung zu optimieren, ist vorgesehen, dass mindestens ein Zwischenglied als mit dem Anker (30) gekoppelter Drehhebel (z. B. 22) ausgebildet ist, der mit einem Kontaktträger (z B. 13) schwenkbar gekoppelt ist, und dass ein anderer Kontaktträger (z. B. 14) mit einem weiteren Drehhebel (z. B. 23) oder unmittelbar mit dem Anker (30) schwenkbar gekoppelt ist, wobei beim Kontaktieren beide Kontaktträger (13, 14) mit den zu kontaktierenden Kontakten (11, 11') aufeinander zu bewegt werden.
摘要翻译：本发明通过一个电枢（30）和至少一个另外的机械接口，其包括可操作地接触单元（10）与接触装置涉及一种用于与一个支撑底座（50）中的去纤颤器的继电器在其上的线圈（40）和通过电激励被安装，其中（12，13,14）由在其上可通过驱动彼此线圈（40）被带到接触载体（11，11“）接触承载。为了优化接触，它提供了至少一个中间构件作为所述电枢（30），其联接旋转杆（Z。B. 22）形成，其被枢转地联接到接触载体（例如13），并且另一接触载体（Z。B. 14）进一步的旋转杆（Z。B. 23）或直接连接到所述电枢（30）被枢转地联接，其中，在接触两个接触载体（13，14）被接触接点（11，11 “）朝向彼此移动。

4. 发明申请

WO2007135599A2 SIMPLIFIED BIPHASIC DEFIBRILLATOR CIRCUIT WITH MAKE-ONLY SWITCHING 审中-公开
标题翻译：简单的双向除颤器电路，只需要切换
公开(公告)号：WO2007135599A2
公开(公告)日：2007-11-29
申请号：PCT/IB2007051775
申请日：2007-05-10
申请人： KONINKL PHILIPS ELECTRONICS NV , POWERS DANIEL J
发明人： POWERS DANIEL J
CPC分类号： A61N1/3906 , A61N1/3912
摘要： A biphasic pulse delivery circuit for a defibrillator includes two capacitors, a first one of which is charged and delivers the first phase of the biphasic pulse and a second one of which is charged and delivers the second phase of the biphasic pulse. At least a portion of the charge on the second capacitor is provided by the current flow through the patient during delivery of the first pulse phase. Switches are provided for initiating the first phase, initiating the second phase, and terminating the second phase. In an illustrated circuit a shunt circuit path is provided to at least partially charge the second capacitor from the first capacitor prior to delivery of the second phase of the biphasic pulse. The inventive circuit can be controlled entirely with switching devices that only need to be closed during pulse delivery.
摘要翻译：用于去纤颤器的双相脉冲输送电路包括两个电容器，其中第一个电容器被充电并输送双相脉冲的第一相，并且其中第二相被充电并输送双相脉冲的第二相。第二电容器上的电荷的至少一部分由在输送第一脉冲相位期间通过患者的电流提供。提供开关以启动第一阶段，启动第二阶段并终止第二阶段。在示出的电路中，提供分流电路路径以在传送第二相的双相脉冲之前，从第一电容器至少部分地对第二电容器充电。本发明的电路可以完全由在脉冲输送期间仅需要关闭的开关装置来控制。

5. 发明申请

WO1997049457A1 BIPHASIC DEFIBRILLATION CIRCUITRY 审中-公开
标题翻译：双向断线电路
公开(公告)号：WO1997049457A1
公开(公告)日：1997-12-31
申请号：PCT/US1997011421
申请日：1997-06-26
申请人： SURVIVALINK CORPORATION
发明人： SURVIVALINK CORPORATION , STENDAHL, Gary, B. , BREWER, James, E.
IPC分类号： A61N01/39
CPC分类号： A61N1/3925 , A61N1/3912 , A61N1/3931 , A61N1/3981
摘要： This invention is an apparatus for providing and delivery biphasic waveform defibrillation pulse. One embodiment includes a source (12) for generating a train of high frequency pulses coupled through a pulse transformer (14), a high speed diode (18) connected to the pulse transformer, a filter capacitor (20) connected to the high speed diode, acting as a low pass filter for the train of pulses, and a plurality of solid state switches (24, 26) for selectively coupling and decoupling the voltage across the filter capacitor to one of a plurality of capacitor banks (40, 42) which make-up the biphasic high voltage defibrillation pulse supply. Another embodiment is an apparatus for selecting from a pair of capacitor banks for delivery of positive and negative polarity portions of a biphasic defibrillator pulse. A further embodiment is a solid state patient isolator circuit capable of conducting bipolar portions of a biphasic defibrillation pulse when the isolator circuit is ON, and further capable of isolating circuitry upstream or downstream of the patient isolator when the isolator circuit is OFF.
摘要翻译：本发明是用于提供和输送双相波形除颤脉冲的装置。一个实施例包括用于产生通过脉冲变压器（14）耦合的高频脉冲串的源极（12），连接到脉冲变压器的高速二极管（18），连接到高速二极管，用作脉冲序列的低通滤波器，以及多个固态开关（24,26），用于选择性地将滤波电容器两端的电压耦合和去耦合到多个电容器组（40,42）中的一个，其中补充双相高压除颤脉冲电源。另一个实施例是用于从一对电容器组中选择用于传输双相除颤器脉冲的正极性和负极性部分的装置。另一个实施例是一种固态病人隔离器电路，当隔离器电路接通时能够传导双相除颤脉冲的双极部分，并且当隔离电路断开时，还能够隔离病人隔离器的上游或下游的电路。

6. 发明申请

WO1997022382A1 OPTICALLY CONTROLLED HIGH-VOLTAGE SWITCH FOR AN IMPLANTABLE DEFIBRILLATOR 审中-公开
标题翻译：用于可植入式除颤器的光控高压开关
公开(公告)号：WO1997022382A1
公开(公告)日：1997-06-26
申请号：PCT/US1996020355
申请日：1996-12-18
申请人： INTERMEDICS, INC. , COX, Timothy, J. , ARMSTRONG, Scott, A.
发明人： INTERMEDICS, INC.
IPC分类号： A61N01/39
CPC分类号： A61N1/3931 , A61N1/3912
摘要： An implantable defribillator with an optically-controlled high-voltage switch. A three-terminal high-voltage-tolerant semiconductor switch (88) exhibits high conductivity between its high-voltage terminal (HV) and its common terminal (COM) in response to a low control voltage applied between its control terminal (CRT) and its common terminal (COM), where the low control voltage exceeds a characteristic threshold value, and exhibits low conductivity between same where the control voltage is less than the characteristic threshold value. A photovoltaic coupler/isolator (82) having a light emitting device (90) and a photovoltaic device (92), optically coupled to and electrically isolated from each other, is in circuit communication across the control and common terminals. A low voltage current source (80) drives the light emitting device (90) of the photovoltaic coupler/isolator (82). A switch-off opto-isolator (84) having a light emitting device (94) and a light sensitive conductive device (96), optically coupled to and electrically isolated from each other, is in circuit communication across the control and common terminals of the semiconductor switch (88). A switch-off low voltage current source (86) drives the light emitting device (94) of the switch-off opto-isolator having a light sensitive conductive device, optically coupled and electrically isolated from each other, is in series circuit communication between the photovoltaic device and the semiconductor switch. A switch-on low voltage current source drives the light emitting device of the switch-on opto-isolator.
摘要翻译：具有光控高压开关的可植入去颤器。响应于在其控制端（CRT）和其控制端（CRT）之间施加的低控制电压，三端子高耐压半导体开关（88）在其高压端子（HV）和其公共端子（COM）公共端（COM），其中低控制电压超过特征阈值，并且在控制电压小于特征阈值的相同之间表现出低导电性。具有发光器件（90）和光电器件（92）的光电耦合器/隔离器（82）在光学上彼此耦合并且彼此电绝缘，跨越控制和公共端子进行电路通信。低压电流源（80）驱动光伏耦合器/隔离器（82）的发光器件（90）。具有发光装置（94）和光敏导电装置（96）的关闭光隔离器（84）在光学上彼此耦合并彼此电隔离，在电路通信中跨越控制和公共端半导体开关（88）。关闭低电压电流源（86）驱动具有光敏耦合和彼此电隔离的光敏导电装置的关闭光隔离器的发光装置（94）在串联电路光伏器件和半导体开关。接通的低压电流源驱动开关式光隔离器的发光器件。

7. 发明申请

WO1996023546A1 METHODS AND APPARATUS FOR APPLYING CHARGE-BALANCED ANTIARRHYTHMIA SHOCKS 审中-公开
标题翻译：用于应付电荷平衡型抗惊厥症的方法和装置
公开(公告)号：WO1996023546A1
公开(公告)日：1996-08-08
申请号：PCT/US1996001188
申请日：1996-01-26
申请人： PACESETTER, INC.
发明人： PACESETTER, INC. , MOUCHAWAR, Gabriel
IPC分类号： A61N01/39
CPC分类号： A61N1/3956 , A61N1/3906 , A61N1/3912
摘要： Methods and apparatus are provided for generating multiphasic charge balanced cardio-version and defibrillation shocks to apply to a patient's heart to terminate episodes of arrhythmia such as tachycardia and fibrillation. In operation, capacitor (82) is charged to a desired energy level via battery (80) and voltage boosting circuitry (79) under the direction of control circuitry (74) which also directs the switching circuitry (84) to reverse the polarity of the applied shock to ensure that the shock is charge balanced (i.e., the time integrated positive shock phase current equals the time integrated negative shock phase current). The use of charge balanced shocks has been determined to significantly reduce the effects of post shock block that result when conventional shocks are applied to the heart.
摘要翻译：提供了用于产生多相电荷平衡心电图和除颤电击的方法和装置，以应用于患者的心脏以终止心律失常发作，例如心动过速和颤动。在操作中，电容器（82）在控制电路（74）的指导下经由电池（80）和升压电路（79）被充电到期望的能级，其也引导开关电路（84）反转应用冲击以确保冲击是电荷平衡（即积分正冲击相电流等于时间积分负冲击相电流的时间）。已经确定使用电荷平衡冲击，以显着减少在将常规冲击应用于心脏时产生的后冲击阻滞的影响。

8. 发明申请

WO1996020755A1 TRUNCATED PULSE DEFIBRILLATOR WITH FLASH TUBE SWITCH 审中-公开
标题翻译：截止脉冲除颤器与闪光管开关
公开(公告)号：WO1996020755A1
公开(公告)日：1996-07-11
申请号：PCT/US1995017052
申请日：1995-12-28
申请人： LAERDAL MEDICAL CORPORATION
发明人： LAERDAL MEDICAL CORPORATION , FOSSAN, Helge , BENSON, Jonathan, M.
IPC分类号： A61N01/39
CPC分类号： A61N1/39 , A61N1/3912
摘要： A defibrillator (20) utilizes at least one flash tube (26) for switching electrical energy from an energy source (36) to a heart patient (42). The flash tube has a high impedance state in which the patient is isolated from the energy. In response to a triggering pulse, the flash tube enters a low impedance state in which energy is delivered to the patient. An additional switching element (24) in the defibrillator operates to interrupt energy delivery through the flash tube so that the truncated defibrillation pulse having a desired energy level is produced.
摘要翻译：除颤器（20）利用至少一个闪光管（26）将电能从能量源（36）切换到心脏病人（42）。闪光管具有高阻抗状态，其中患者与能量隔离。响应于触发脉冲，闪光管进入能量被传递给患者的低阻抗状态。去纤颤器中的附加开关元件（24）操作以中断通过闪光管的能量传递，从而产生具有期望能级的截断除颤脉冲。

9. 发明申请

WO1995016492A1 METHOD AND APPARATUS UTILIZING SHORT TAU CAPACITORS 审中-公开
标题翻译：利用短路电容器的方法和装置
公开(公告)号：WO1995016492A1
公开(公告)日：1995-06-22
申请号：PCT/US1994014201
申请日：1994-12-12
申请人： ANGEION CORPORATION
发明人： ANGEION CORPORATION , KROLL, Mark, W. , KROLL, Kai, C.
IPC分类号： A61N01/36
CPC分类号： A61N1/3956 , A61N1/3912
摘要： This invention is an implantable cardioverter defibrillator for treating cardiac dysrhythmias utilizing an interrupted discharge output provided by a switch control means (206) to vary the duty cycle of a switch (208) incorporated within the output circuitry of the implanted cardioverter defibrillator so as to increase the efficiency by extending the duration of the discharge for capacitor systems having time constants tau, less than about the chronaxie value of the human heart. As a result the implantable cardioverter defibrillator produces a more favorable rectangular-like waveform from the discharge of a significantly smaller capacitor than the capacitors used in existing implantable cardioverter defibrillators.
摘要翻译：本发明是一种植入式心律转复除颤器，用于利用由开关控制装置（206）提供的中断放电输出来治疗心律失常，以改变并入植入式心律转复除颤器的输出电路内的开关（208）的占空比，从而增加通过将具有时间常数τ的电容器系统的放电持续时间延长，小于约人的心脏的长时间值来提高效率。因此，植入式心律转复除颤器从与现有可植入式心律转复除颤器中使用的电容器相比显着更小的电容器的放电产生更有利的矩形波形。

10. 发明申请

WO1994021327A1 EXTERNAL DEFIBRILLATOR CIRCUIT 审中-公开
标题翻译：外部除颤器电路
公开(公告)号：WO1994021327A1
公开(公告)日：1994-09-29
申请号：PCT/US1994002783
申请日：1994-03-15
申请人： SURVIVALINK CORPORATION
发明人： SURVIVALINK CORPORATION , PERSSON, Eric
IPC分类号： A61N01/39
CPC分类号： A61N1/39 , A61N1/3912
摘要： A portable, automatic external defibrillator (10), comprising a plurality of capacitors (C1-Cn); a capacitor charging circuit (25); connections from the capacitors to a patient body; and a plurality of semiconductor switches (S1-Sn) arranged to connect the capacitors to the charging circuit and to the body of the patient.
摘要翻译：一种便携式自动外部除颤器（10），包括多个电容器（C1-Cn）; 电容充电电路（25）; 从电容器到患者身体的连接; 以及布置成将电容器连接到充电电路和患者身体的多个半导体开关（S1-Sn）。

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