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1. 发明申请

WO2016054687A1 SUTURELESS REPAIR OF SOFT TISSUE 审中-公开
标题翻译：软组织的无法修复
公开(公告)号：WO2016054687A1
公开(公告)日：2016-04-14
申请号：PCT/AU2015/000612
申请日：2015-10-12
申请人： ORTHOCELL LIMITED
发明人： ZHENG, Ming, Hao
IPC分类号： A61L15/32 , A61L27/58 , A61F2/08
CPC分类号： A61F2/08 , A61B17/00491 , A61B17/11 , A61B17/1128 , A61B17/1146 , A61B2017/00508 , A61B2017/0065 , A61B2017/00659 , A61B2017/1107 , A61B2017/1132 , A61F2/0036 , A61L27/24 , A61L27/50 , A61L2430/10 , A61L2430/34
摘要： The present invention relates to a sutureless method of repairing soft tissue defects in soft tissue including ligaments such as anterior cruciate ligaments (ACLs). Jn particular, the present invention relates a sutureless method of repairing soft tissue defect comprising: (i) providing a collagen-containing patch adapted to enclose at least a portion of said soft tissue defect; (ii) contacting said soft tissue defect and/or collagen-containing patch with a sensitizer; (Hi) enclosing said soft tissue defect in said collagen-containing patch to produce a bioactivc chamber; and (iv) adhering said collagen-containing patch to said soft tissue defect without sutures.
摘要翻译：本发明涉及一种修复软组织软组织缺损的无缝合方法，包括诸如前十字韧带（ACL）的韧带。具体地说，本发明涉及一种修复软组织缺损的无缝线方法，包括：（i）提供适于包围所述软组织缺损的至少一部分的含胶原的贴剂; （ii）使所述软组织缺损和/或含胶原的贴片与敏化剂接触; （Hi），在所述含胶原蛋白的贴片中包围所述软组织缺损以产生生物活化室; 和（iv）在没有缝合的情况下将所述含胶原蛋白的贴片粘附到所述软组织缺损。

2. 发明申请

WO2015135975A1 ABSORBABLE TISSUE RECONSTRUCTION DEVICE, IN PARTICULAR FOR TISSUES SUCH AS LIGAMENTS 审中-公开
标题翻译：可吸收的组织重建装置，特别是用作组织的组织
公开(公告)号：WO2015135975A1
公开(公告)日：2015-09-17
申请号：PCT/EP2015/055045
申请日：2015-03-11
申请人： SAMBUSSETI, Antonio
发明人： SAMBUSSETI, Antonio
IPC分类号： A61B17/11
CPC分类号： A61B17/1146 , A61B2017/00004
摘要： There is described an absorbable device (1) for the connection and reconstruction of a ligament, comprising a central reconstruction portion (9) and two connecting 5 ends (10a, 10b) at the two ends of said central portion (9), characterized in that in said connecting device, said two connecting ends (10a, 10b) comprise two retaining portions (11a, 11b), respectively, for receiving fixing means adapted to fix said device (1) to said ligament.
摘要翻译：描述了用于连接和重建韧带的可吸收装置（1），包括在所述中心部分（9）的两端处的中心重建部分（9）和两个连接的5端（10a，10b），其特征在于在所述连接装置中，所述两个连接端（10a，10b）分别包括两个保持部分（11a，11b），用于接收适于将所述装置（1）固定到所述韧带的固定装置。

3. 发明申请

WO2015026295A1 TENDON REPAIR SYSTEMS, DEVICES, AND KITS 审中-公开
标题翻译： TENDON维修系统，设备和工具
公开(公告)号：WO2015026295A1
公开(公告)日：2015-02-26
申请号：PCT/SG2014/000388
申请日：2014-08-18
申请人： CAPERE SURGICAL SYSTEMS PTE LTD.
发明人： LIM, Beng Hai , CHOU, Siaw Meng
IPC分类号： A61B17/04 , A61B17/11
CPC分类号： A61F2/0811 , A61B17/0401 , A61B17/0466 , A61B17/0487 , A61B17/0644 , A61B17/0682 , A61B17/1146 , A61B2017/0409 , A61B2017/0412 , A61B2017/0414 , A61B2017/042 , A61B2017/0464 , A61F2/08 , A61F2/0805 , A61F2002/0864 , A61F2220/0016
摘要： A tendon overlay device includes an arcuate main body having an outer surface and an inner surface, each of the outer surface and the inner surface extending between a first terminal edge of the main body and a second terminal edge of the main body; a first plurality of teeth disposed along the first terminal edge of the main body; and a second plurality of teeth disposed along the second terminal edge of the main body. Each tooth within the first plurality of teeth projects downward away from the first terminal edge of the main body and is biased inward toward the second plurality of teeth. Each tooth within the second plurality of teeth projects downward away from the second terminal edge of the main body and is biased inward toward the first plurality of teeth. The inner surface of the main body excludes spikes and serrations that can penetrate into an outer surface of a tendon on which the inner surface of the main body is disposable.
摘要翻译：腱覆盖装置包括具有外表面和内表面的弓形主体，每个外表面和内表面在主体的第一端边缘和主体的第二端边之间延伸; 沿着主体的第一端边缘设置的第一多个齿; 以及沿着主体的第二终端边缘设置的第二多个齿。第一多个齿内的每个齿从主体的第一末端边缘向下突出，并朝向第二多个齿向内偏置。第二多个齿内的每个齿从主体的第二终端边缘向下突出，并朝向第一多个齿向内偏置。主体的内表面不包括可以穿透主体内表面一次性的腱的外表面的尖峰和锯齿。

4. 发明申请

WO2014138467A1 APPARATUS AND METHOD FOR REGENERATION OF LIGAMENTS AND TENDONS 审中-公开
标题翻译：装置和方法，用于再生大型和绅士
公开(公告)号：WO2014138467A1
公开(公告)日：2014-09-12
申请号：PCT/US2014/021377
申请日：2014-03-06
申请人： UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
发明人： WOO, Savio, L Y , FARRARO, Katie , SPEZIALI, Andrea , KIM, Kwang, Eun , MCMAHON, Patrick, J.
IPC分类号： A61B17/115 , A61B17/04
CPC分类号： A61F2/0811 , A61B17/0401 , A61B17/1146 , A61B17/8695 , A61B2017/00004 , A61B2017/0414 , A61B2017/0417 , A61B2017/0445 , A61B2017/0464 , A61B2017/1132 , A61F2002/0817 , A61F2002/0847 , A61F2002/0882 , A61F2210/0004 , A61F2220/0016 , A61F2230/0067 , A61F2230/0069
摘要： A method for repairing a ligament or tendon, the method comprising: passing one or more sutures through and/or around each respective end of a completely or partially torn ligament or tendon; placing a generally cylindrical hollow body or ring over the respective ends of the completely or partially torn ligament or tendon; passing the one or more sutures through the generally cylindrical hollow body or ring; and tying the one or more sutures around or through the generally cylindrical hollow body or ring wherein the sutures are secured in place around or through the generally cylindrical hollow body or ring via one or more notches or holes defined by the generally cylindrical hollow body or ring. The method may further comprise tensioning the one or more sutures while tying them around or through the generally cylindrical hollow body or ring so that the respective ends of the completely or partially torn ligament or tendon are brought into and stay in contact with each other inside the generally cylindrical hollow body or ring after the tying is complete. The generally cylindrical hollow body or ring preferably is biodegradable and may be coated with an ECM.
摘要翻译：一种用于修复韧带或腱的方法，所述方法包括：使一个或多个缝合线穿过完全或部分撕裂的韧带或腱的每个相应端部和/或周围; 将大致圆柱形的空心体或环放置在完全或部分撕裂的韧带或腱的相应末端上; 使一根或多根缝线穿过大致圆柱形的中空体或环; 并且将所述一个或多个缝合线围绕或穿过所述大致圆柱形的中空本体或环，其中所述缝线通过所述大致圆柱形的中空本体或环限定的一个或多个凹口或孔固定在所述大致圆柱形的中空本体或环周围或穿过所述大致圆柱形的中空本体或环。所述方法还可以包括在将所述一个或多个缝合线捆扎在所述一个或多个缝合线周围或穿过所述大致圆柱形的中空本体或环时张紧所述一个或多个缝合线，使得所述完全或部分撕裂的韧带或腱的相应端部进入并保持在其内部大致圆柱形的空心体或环后绑扎完成。大致圆柱形的中空体或环优选是可生物降解的并且可以用ECM涂覆。

5. 发明申请

WO2011146765A1 TISSUE FIXATION 审中-公开
标题翻译：组织固定
公开(公告)号：WO2011146765A1
公开(公告)日：2011-11-24
申请号：PCT/US2011/037233
申请日：2011-05-19
申请人： UNIVERSITY OF UTAH RESEARCH FOUNDATION , KUBIAK, Erik, N. , CHEN, Emmon, J. , GRAINGER, David, W.
发明人： KUBIAK, Erik, N. , CHEN, Emmon, J. , GRAINGER, David, W.
IPC分类号： A61B17/08
CPC分类号： A61B17/1146 , A61B2017/00004 , A61B2017/00526 , A61F2/08 , A61F2/0811
摘要： Methods and apparatuses are provided for tissue fixation. In some aspects, an apparatus includes: a carrier member having a first part, a second part, and a junction therebetween; first attachment members protruding at a first angle from the first part toward the junction, where the first attachment members are configured to engage a first portion of connective tissue for attaching the first part to the first portion; and second attachment members protruding from the second part, where the second attachment members are configured to engage a second portion of connective tissue for attaching the second part to the second portion. When the first part is attached to the first portion and the second part is attached to the second portion, the first portion and the second portion are limited in being pulled apart from one another during physiological use of the connective tissue.
摘要翻译：提供了用于组织固定的方法和装置。在一些方面，一种装置包括：承载构件，其具有第一部分，第二部分和它们之间的连接点; 第一附接构件从第一部分朝向接合部以第一角度突出，其中第一附接构件构造成接合连接组织的第一部分，以将第一部分附接到第一部分; 以及第二附接构件，其从所述第二部分突出，其中所述第二附接构件被构造成接合所述结缔组织的第二部分，以将所述第二部分附接到所述第二部分。当第一部分附接到第一部分并且第二部分附接到第二部分时，第一部分和第二部分被限制为在结缔组织的生理使用期间彼此分离。

6. 发明申请

WO2010099222A1 METHODS AND DEVICES FOR UTILIZING BONDABLE MATERIALS 审中-公开
标题翻译：用于使用粘结材料的方法和装置
公开(公告)号：WO2010099222A1
公开(公告)日：2010-09-02
申请号：PCT/US2010/025263
申请日：2010-02-24
申请人： P TECH, LLC , BONUTTI, Peter, M. , BEYERS, Justin, E. , CREMENS, Matthew, J.
发明人： BONUTTI, Peter, M. , BEYERS, Justin, E. , CREMENS, Matthew, J.
IPC分类号： A61B17/08
CPC分类号： A61B17/8836 , A61B17/0401 , A61B17/11 , A61B17/1128 , A61B17/1146 , A61B17/320068 , A61B17/68 , A61B17/7059 , A61B17/7233 , A61B17/7266 , A61B17/866 , A61B17/8685 , A61B17/88 , A61B17/8872 , A61B2017/005 , A61B2017/0409 , A61B2017/044 , A61B2017/1107 , A61F2/0811 , A61F2/30 , A61F2/30721 , A61F2/30756 , A61F2/3094 , A61F2/32 , A61F2/34 , A61F2/36 , A61F2/3603 , A61F2/38 , A61F2/3804 , A61F2/3859 , A61F2/389 , A61F2/40 , A61F2/4081 , A61F2/4202 , A61F2/44 , A61F2/4455 , A61F2/46 , A61F2/468 , A61F2002/067 , A61F2002/2817 , A61F2002/30062 , A61F2002/30065 , A61F2002/30067 , A61F2002/30133 , A61F2002/30451 , A61F2002/30576 , A61F2002/30604 , A61F2002/30677 , A61F2002/3068 , A61F2002/30785 , A61F2002/30787 , A61F2002/30878 , A61F2002/30892 , A61F2002/30894 , A61F2002/30971 , A61F2002/30973 , A61F2002/3401 , A61F2002/3403 , A61F2002/444 , A61F2002/4619 , A61F2002/4683 , A61F2210/0004 , A61F2210/0071 , A61F2220/0058 , A61F2230/0015 , A61F2250/0068 , A61F2310/00011 , A61F2310/00365 , A61F2310/00383 , A61F2310/00952 , A61L24/001 , A61L24/046 , C08L33/04
摘要： The invention primarily relates to fastening and stabilizing tissues, implants, and/or bondable materials, such as the fastening of a tissue and/or implant to a bondable material, the fastening of an implant to tissue, and/or the fastening of an implant to another implant. This may involve using an energy source to bond and/or mechanically to stabilize a tissue, an implant, a bondable material, and/or other biocompatible material. The invention may also relate to the use of an energy source to remove and/or install an implant and/or bondable material or to facilitate solidification and/or polymerization of bondable material.
摘要翻译：本发明主要涉及紧固和稳定组织，植入物和/或可结合材料，例如将组织和/或植入物紧固到可结合材料，将植入物紧固到组织和/或固定植入物到另一种种植体。这可能涉及使用能源来结合和/或机械地稳定组织，植入物，可结合材料和/或其它生物相容性材料。本发明还可以涉及能量源的使用以去除和/或安装植入物和/或可结合材料或促进可结合材料的固化和/或聚合。

7. 发明申请

WO2009102967A2 MOLECULAR ENHANCEMENT OF EXTRACELLULAR MATRIX AND METHODS OF USE 审中-公开
标题翻译：细胞基质的分子增强和使用方法
公开(公告)号：WO2009102967A2
公开(公告)日：2009-08-20
申请号：PCT/US2009034071
申请日：2009-02-13
申请人： CLEVELAND CLINIC FOUNDATION , DERWIN KATHLEEN ANNE , IANNOTTI JOSEPH PATRICK , CHIN LIKANG , CALABRO ANTHONY
发明人： DERWIN KATHLEEN ANNE , IANNOTTI JOSEPH PATRICK , CHIN LIKANG , CALABRO ANTHONY
IPC分类号： A61L27/54 , C08G8/28 , C08G63/91 , C08G73/02 , C08G85/00 , C08J3/22 , C08J3/24
CPC分类号： A61F2/08 , A61B17/1146 , A61L27/3633 , A61L27/48 , C08L89/00 , C08L5/08
摘要： A composition comprising a human- or animal-derived extracellular matrix and a macromolecular network which is prepared ex vivo is provided that is useful in the repair of a tissue injury, particularly in repair of tears or gaps between a tendon and a bone, such as in a rotator cuff tear. In an embodiment, the composition comprises a human- or animal-derived extracellular matrix having impregnated therein a macromolecular network of hyaluronan macromolecules that have been cross-linked via dihydroxyphenyl linkages, so that the cross-linked network is interlocked within the extracellular matrix. The resulting HA-incorporated extracellular matrix can be supplied in the form of a patch to reinforce a tissue repair or cover a tissue defect.
摘要翻译：提供了包含人或动物衍生的细胞外基质和离体制备的大分子网络的组合物，其可用于修复组织损伤，特别是修复腱和骨之间的泪液或间隙，例如在肩袖撕裂。在一个实施方案中，组合物包含其中浸渍有通过二羟基苯基键交联的透明质酸大分子的大分子网络的人或动物衍生的细胞外基质，使得交联网络在细胞外基质内互锁。所得到的HA结合的细胞外基质可以以补片的形式提供，以加强组织修复或覆盖组织缺损。

8. 发明申请

WO2007092869A3 METHODS AND DEVICES FOR INTRACORPOREAL BONDING OF IMPLANTS WITH THERMAL ENERGY 审中-公开
标题翻译：具有热能的植入物的内在结合的方法和装置
公开(公告)号：WO2007092869A3
公开(公告)日：2007-12-13
申请号：PCT/US2007061730
申请日：2007-02-07
申请人： MARCTEC LLC , BONUTTI PETER M , CREMENS MATTHEW J , BEYERS JUSTIN E
发明人： BONUTTI PETER M , CREMENS MATTHEW J , BEYERS JUSTIN E
IPC分类号： A61B17/56 , A61F2/28
CPC分类号： A61B17/7233 , A61B17/0401 , A61B17/11 , A61B17/1128 , A61B17/1146 , A61B17/1721 , A61B17/1742 , A61B17/320068 , A61B17/686 , A61B17/7032 , A61B17/7058 , A61B17/7059 , A61B17/7062 , A61B17/72 , A61B17/725 , A61B17/80 , A61B17/8033 , A61B17/8038 , A61B17/82 , A61B17/866 , A61B17/8685 , A61B17/88 , A61B17/8863 , A61B2017/00004 , A61B2017/00504 , A61B2017/0409 , A61B2017/044 , A61B2017/8655 , A61F2/30756 , A61F2/32 , A61F2/3603 , A61F2/38 , A61F2/3804 , A61F2/3859 , A61F2/389 , A61F2/40 , A61F2/4081 , A61F2/4202 , A61F2/4455 , A61F2/468 , A61F2002/2817 , A61F2002/30062 , A61F2002/30065 , A61F2002/30133 , A61F2002/30451 , A61F2002/30604 , A61F2002/30677 , A61F2002/3068 , A61F2002/30785 , A61F2002/30787 , A61F2002/30878 , A61F2002/30892 , A61F2002/30894 , A61F2002/30971 , A61F2002/30973 , A61F2002/3401 , A61F2002/3403 , A61F2002/444 , A61F2002/828 , A61F2210/0004 , A61F2210/0071 , A61F2220/0058 , A61F2230/0015 , A61F2250/0068 , A61F2310/00011 , A61F2310/00365 , A61F2310/00383 , G06F21/10 , G06F2221/0773 , G06F2221/2137
摘要： The present invention provides a method for stabilizing a fractured bone. The method includes positioning an elongate rod in the medullary canal of the fractured bone and forming a passageway through the cortex of the bone. The passageway extends from the exterior surface of the bone to the medullary canal of the bone. The method also includes creating a bonding region on the elongate rod. The bonding region is generally aligned with the passageway of the cortex. Furthermore, the method includes positioning a fastener in the passageway of the cortex and on the bonding region of the elongate rod and thermally bonding the fastener to the bonding region of the elongate rod while the fastener is positioned in the passageway of the cortex.
摘要翻译：本发明提供了一种稳定骨折骨的方法。该方法包括将细长杆定位在骨折的骨髓中并形成穿过骨皮质的通道。通道从骨的外表面延伸到骨的髓管。该方法还包括在细长杆上形成结合区域。结合区域通常与皮质通道对准。此外，该方法包括将紧固件定位在皮质通道和细长杆的接合区域上，并将紧固件热粘合到细长杆的接合区域，同时紧固件位于皮质通道中。

9. 发明申请

WO2004112619A1 TENDON SUTURE AID 审中-公开
公开(公告)号：WO2004112619A1
公开(公告)日：2004-12-29
申请号：PCT/GB2004/002532
申请日：2004-06-11
申请人： GLASGOW SCHOOL OF ART , RICHARDS, Samuel, Charles
发明人： RICHARDS, Samuel, Charles
IPC分类号： A61B17/11
CPC分类号： A61B17/1146 , A61B2017/1103
摘要： The invention relates to a medical device that assists in the gripping, locating and suturing of severed tendon ends. In particular, the device aids the gripping, locating and suturing of severed ends of flex tendons, resulting in less tendon damage during surgery, as there is less dragging, pulling and lengthy clamping of the tendon ends.
摘要翻译：本发明涉及一种有助于夹持，定位和缝合切断的肌腱端部的医疗装置。特别地，该装置有助于夹持，定位和缝合柔性筋的切断端，导致手术期间较少的腱损伤，因为腱端部的拖曳，牵拉和长度夹紧较少。

10. 发明申请

WO0189392A3 TISSUE APPROXIMATION DEVICE AND A METHOD USING IT 审中-公开
标题翻译：组织近似装置及其使用方法
公开(公告)号：WO0189392A3
公开(公告)日：2002-05-30
申请号：PCT/US0116346
申请日：2001-05-17
申请人： COAPT SYSTEMS INC , JACOBS DANIEL , ELSON ROBERT JAMES , PAGANELLI JUDE V
发明人： JACOBS DANIEL , ELSON ROBERT JAMES , PAGANELLI JUDE V
IPC分类号： A61B17/00 , A61B17/04 , A61B17/064 , A61B17/08 , A61B17/11 , A61B17/56 , A61B17/58 , A61B19/00 , A61F2/00 , A61L31/00
CPC分类号： A61B17/11 , A61B17/064 , A61B17/0643 , A61B17/08 , A61B17/085 , A61B17/1128 , A61B17/1146 , A61B90/02 , A61B2017/00004 , A61B2017/0496 , A61B2017/0641 , A61B2017/0647 , A61B2017/0648 , A61B2017/081 , A61B2017/1107
摘要： A tissue approximation device and processes for using the device are provided. The device is an implantable, biodegradable construct (except for hernia repairs) that has attachment points emanating from a supportive backing. The device improves the mechanical phase of wound healing and evenly distributes tension over the contact area between the device and tissue. Processes for using the device include wound closure, vascular anastomoses, soft tissue attachment and soft tissue to bone attachment. Several variations are particularly applicable to facilitating tissue approximation in surgical cosmetic applications including, for example, orbital rim reconstruction and tissue suspension.
摘要翻译：提供组织近似装置和使用装置的方法。该装置是可植入的，可生物降解的构造物（除了疝修补物），其具有从支撑背衬产生的附着点。该装置改善伤口愈合的机械相，并均匀地分布在装置和组织之间的接触区域上的张力。使用该装置的方法包括伤口闭合，血管吻合，软组织附着和软组织至骨附着。几种变型特别适用于促进手术美容应用中的组织近似，包括例如轨道边缘重建和组织悬浮。

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