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    • 7. 发明申请
    • INORGANIC NANOTUBES AND DEVICES FABRICATED THEREFROM
    • 无机纳米管及由此制造的器件
    • WO2008039579A2
    • 2008-04-03
    • PCT/US2007071300
    • 2007-06-15
    • UNIV CALIFORNIAYANG PEIDONGMAJUMDAR ARUNAVAFAN RONGKARNIK ROHITCASTELINO KENNETH
    • YANG PEIDONGMAJUMDAR ARUNAVAFAN RONGKARNIK ROHITCASTELINO KENNETH
    • C12M3/00
    • G01N27/4146B01L3/5027G01N27/4145
    • Nanofluidic devices are taught incorporating inorganic nanotubes fluidly coupled to channels or nanopores for supplying a fluid containing chemical or biochemical species. In one aspect, two channels are fluidly interconnected with a nanotube. Electrodes on opposing sides of the nanotube establish electrical contact with the fluid therein. A bias current is passed between the electrodes through the fluid, and current changes are detected to ascertain the passage of select molecules, such as DNA, through the nanotube. In another inventive aspect, a gate electrode is located proximal the nanotube between the two electrodes thus forming a nanofluidic transistor. The voltage applied to the gate controls the passage of ionic species through the nanotube selected as either or both ionic polarities. In either of these aspects the nanotube can be modified, or functionalized, to control the selectivity of detection or passage.
    • 教导纳米流体装置,其结合流体耦合到通道或纳米孔的无机纳米管,用于供应含有化学或生物化学物质的流体。 在一个方面,两个通道与纳米管流体相互连接。 纳米管相对侧上的电极与其中的流体建立电接触。 偏置电流通过流体在电极之间传递,并且检测电流变化以确定选择分子(例如DNA)通过纳米管的通过。 在另一发明方面,栅电极位于两个电极之间的纳米管附近,从而形成纳米流体晶体管。 施加到栅极的电压控制离子物质通过选择为或者两个离子极性的纳米管。 在这些方面中的任一方面中,纳米管都可以被改性或官能化,以控制检测或通过的选择性。