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1. 发明申请

WO2007130526A3 ULTRASOUND SCANNING AND ULTRASOUND- ASSISTED BIOPSY 审中-公开
标题翻译：超声扫描和超声辅助生物
公开(公告)号：WO2007130526A3
公开(公告)日：2008-10-30
申请号：PCT/US2007010753
申请日：2007-05-02
申请人： U SYSTEMS INC , WANG SHIH-PING , SUMMERS DOUGLAS G , ANDERSON TOR C , CHEN JIAYU
发明人： WANG SHIH-PING , SUMMERS DOUGLAS G , ANDERSON TOR C , CHEN JIAYU
IPC分类号： A61B5/103
CPC分类号： A61B8/0825 , A61B8/0833 , A61B8/0841 , A61B8/14 , A61B8/4218 , A61B8/4455 , A61B8/4472 , A61B8/4483 , A61B8/54 , G01S15/8934
摘要： An apparatus and related methods for ultrasonically scanning a tissue sample are described, the apparatus comprising an ultrasound transducer and a membranous sheet, the membranous sheet compressing the tissue sample, the ultrasound transducer contacting the membranous sheet and ultrasonically scanning the tissue sample therethrough, wherein the membranous sheet has a generally arcuate shape and the ultrasound transducer is movable in a generally arcuate trajectory therealong during the ultrasonic scan. Also described is an apparatus for facilitating a medical procedure, comprising a membranous sheet compressing a tissue sample, an ultrasound transducer contacting the membranous sheet to ultrasonically scan the tissue sample therethrough, and a biopsy guide operably coupled to the ultrasound transducer for maintaining a biopsy instrument in a scan plane of the ultrasound transducer to facilitate a percutaneous biopsy of a lesion located in the scan plane.
摘要翻译：描述了用于超声波扫描组织样品的装置和相关方法，所述装置包括超声波换能器和膜片，所述膜片压缩所述组织样本，所述超声波换能器与所述膜片接触并且超声扫描所述组织样本，其中，膜片具有大致弓形的形状，并且超声波换能器可在超声波扫描期间沿其大致弧形的轨迹移动。还描述了一种用于促进医疗过程的装置，包括压缩组织样本的膜片，接触膜片的超声波换能器以超声扫描组织样本，以及可操作地耦合到超声换能器的活检导管，用于维持活检器械在超声换能器的扫描平面中，以便于位于扫描平面中的病变的经皮活检。

2. 发明申请

WO2005117711A3 PROCESSING AND DISPLAYING BREAST ULTRASOUND INFORMATION 审中-公开
标题翻译：加工和显示乳房超声信息
公开(公告)号：WO2005117711A3
公开(公告)日：2006-04-06
申请号：PCT/US2005019604
申请日：2005-06-01
申请人： U SYSTEMS INC , ZHANG WEI , WANG SHIH-PING , CHEN JIAYU , YU ZENGPIN , CUPPLES TOMMY EARL , REED MICHAEL E
发明人： ZHANG WEI , WANG SHIH-PING , CHEN JIAYU , YU ZENGPIN , CUPPLES TOMMY EARL , REED MICHAEL E
IPC分类号： A61B6/00 , A61B8/00 , A61B8/08 , A61B8/12 , A61B8/13 , A61B8/14
CPC分类号： A61B8/5238 , A61B6/463 , A61B6/502 , A61B6/5247 , A61B6/563 , A61B8/0825 , A61B8/13 , A61B8/406 , A61B8/4281 , A61B8/4405 , A61B8/462 , A61B8/463 , A61B8/465 , A61B8/466 , A61B8/467 , A61B8/565
摘要： Displaying breast ultrasound information on an interactive user interface is described, the user interface being useful in adjunctive ultrasound mammography environments and/or ultrasound-only mammography environments. Bilateral comparison is facilitated by a pairwise display of thick-slice images corresponding to analogous slab-like subvolumes in the left and right breasts. Coronal thick-slice imaging and convenient navigation on and among coronal thick-slice images is described. In one preferred embodiment, a nipple marker is displayed the coronal thick-slice image representing a projection of a nipple location thereupon. A convenient breast icon is also displayed including a cursor position indicator variably disposed thereon in a manner that reflects a relative position between the cursor and the nipple marker. Preferably, the breast icon is configured to at least roughly resemble a clock face, the center of the clock face representing the nipple marker location. Bookmark-centric and CAD-marker-centric navigation within and among thick-slice images is also described.
摘要翻译：描述了在交互式用户界面上显示乳房超声信息，用户界面在辅助超声乳房X线照相术环境和/或超声乳腺X线照相术环境中是有用的。通过成对显示对应于左乳房和右乳房中类似的板状子体积的双层比较来促进双边比较。描述了冠状厚片成像和冠状厚片图像之间和之间方便的导航。在一个优选实施例中，乳头标记被显示为表示其上的乳头位置的投影的冠状厚片图像。还显示方便的乳房图标，包括以反映光标和乳头标记之间的相对位置的方式可变地设置在其上的光标位置指示器。优选地，乳房图标被配置为至少大致类似于时钟面，时钟面的中心表示乳头标记位置。还描述了厚片图像内和书签中心和CAD标记为中心的导航。

3. 发明申请

WO2004051405A2 FULL-FIELD BREAST IMAGE DATA PROCESSING AND ARCHIVING 审中-公开
标题翻译：全场BREAST图像数据处理和存档
公开(公告)号：WO2004051405A2
公开(公告)日：2004-06-17
申请号：PCT/US0337600
申请日：2003-11-25
申请人： U SYSTEMS INC , YU ZENGPIN , WANG SHIH-PING
发明人： YU ZENGPIN , WANG SHIH-PING
IPC分类号： A61B6/00 , A61B8/00 , A61B8/08 , G06F
CPC分类号： A61B8/5215 , A61B6/463 , A61B6/502 , A61B6/5241 , A61B6/5247 , A61B6/563 , A61B8/0825 , A61B8/406 , A61B8/4281 , A61B8/4405 , A61B8/463 , A61B8/464 , A61B8/465 , A61B8/466 , A61B8/467 , A61B8/5238 , A61B8/565
摘要： A system, computer program product, and related methods are described for obtaining, processing, and/or and archiving full-field breast image data, such as full-field breast ultrasound (FFBU) data, in a manner that promotes ready integration with current x-ray mammogram-based breast cancer screening methodologies, and which can alternatively be used to support a full-field-only environment. Two-dimensional thick-slice images computed from a three-dimensional data volume are used to facilitate efficient archiving for a breast imaging session, the two-dimensional thick-slice images corresponding to slab-like subvolumes of the breast. Clinician data overload problems that can arise from the existence of large amounts of three-dimensional full-field breast image data are reduced. Archive space is also preserved while still providing sufficient information data for future reference purposes. Related adjunctive full-field workflow methods are also described. The described embodiments are applicable to FFBU imaging and other full-field breast imaging modalities such as MRI, CT, PET, and others.
摘要翻译：描述了用于获得，处理和/或归档全场乳房图像数据（例如全场乳房超声（FFBU）数据）的系统，计算机程序产品和相关方法，以促进与当前的现场集成的方式基于x射线乳腺X线摄影的乳腺癌筛查方法，可替代地可用于支持全场纯环境。使用从三维数据体积计算的二维厚片图像来促进乳房成像会话的有效归档，对应于乳房的板状子体积的二维厚片图像。减少了由存在大量三维全场乳房图像数据引起的临床医生数据过载问题。存档空间也得到保留，同时仍然提供足够的信息数据以备将来参考。还描述了相关的辅助全字段工作流程方法。所描述的实施例可应用于FFBU成像和其他全场乳房成像模式，例如MRI，CT，PET等。

4. 发明申请

WO0241751A3 DIAGNOSIS METHOD AND ULTRASOUND INFORMATION DISPLAY SYSTEM THEREFOR 审中-公开
标题翻译：诊断方法及其超声信息显示系统
公开(公告)号：WO0241751A3
公开(公告)日：2003-05-22
申请号：PCT/US0143226
申请日：2001-11-20
申请人： U SYSTEMS INC , CHENG XIANGYONG , WANG SHIH-PING
发明人： CHENG XIANGYONG , WANG SHIH-PING
IPC分类号： A61B8/08 , G01S7/52 , G01S15/89 , G06F17/00
CPC分类号： A61B8/483 , A61B8/0825 , A61B8/463 , A61B8/465 , G01S7/52034 , G01S7/52074 , G01S15/8993
摘要： A method and system for screening and/or diagnosing a tumor in a subject breast using ultrasonically obtained image information is described. A user interface displays a three-dimensional (202) view of the tumor ('206) suspended within a three-dimensional semitransparent view of a breast, the tumor suspended at a position corresponding to the actual position of the tumor inside the breast. A larger, close-up view of the tumor (206) is also provided that a user can manipulate (e.g., rotate, enlarge, etc.) for clearer analysis. A semi-transparent view (204) of the opposing breast is placed adjacent to the semi-transparent view of the subject breast in a manner that reflects the actual positioning of the breasts on the patient's body, or in a manner that emulates a mammogram-like view of the breasts. Alternatively or in conjunction therewith, the user interface displays an animated sequence of ultrasound slices including a highlighted visual indicator of the tumor and an iconic probe position indicator synchronized with the animated sequence.
摘要翻译：描述了使用超声波获得的图像信息来筛选和/或诊断受试者乳房中的肿瘤的方法和系统。用户界面显示悬浮在乳房的三维半透明视图内的肿瘤（'206）的三维（202）视图，所述肿瘤悬挂在与乳房内的肿瘤的实际位置相对应的位置处。还提供了肿瘤（206）的更大的特写视图，用户可以操纵（例如旋转，放大等）以进行更清晰的分析。相对乳房的半透明视图（204）以反映乳房在患者身上的实际位置的方式放置在与主体乳房的半透视图相邻的方式处，或以模拟乳房X线照片的方式放置，像乳房的看法。替代地或与其结合，用户界面显示包括肿瘤的突出显示的视觉指示符和与动画序列同步的图标探测位置指示符的超声切片的动画序列。

5. 发明申请

WO0243801A3 METHOD AND SYSTEM FOR ULTRASOUND BREAST CANCER SCREENING 审中-公开
标题翻译：超声波乳腺癌筛查方法与系统
公开(公告)号：WO0243801A3
公开(公告)日：2003-04-03
申请号：PCT/US0143237
申请日：2001-11-19
申请人： U SYSTEMS INC , WANG SHIH-PING
发明人： WANG SHIH-PING
IPC分类号： A61B6/00 , A61B8/00 , A61B8/08
CPC分类号： A61B8/5238 , A61B6/502 , A61B6/5247 , A61B6/563 , A61B8/0825 , A61B8/4263 , A61B8/4281 , A61B8/463 , A61B8/465 , A61B8/467 , A61B8/565
摘要： A breast cancer screening system having an ultrasound probe (202)that scans a breast (204) that is flattened along an ultrasound-absorbing plate (206). The ultrasound probe (202) takes ultrasound image slices from successive planes in the breast (204) volume substancially parallel to a plane of a predetermined x-ray mammogram view of the breast (204). The ultrasound image slices are preferably displayed adjacent to a display (406) of the x-ray mammogram view itself, such that a screening radiologist may elect to view the ultrasound image slices simultaneously with the x-ray mammogram view. Preferably, the predetermined x-ray mammogram view is a standardized x-ray mammogram view such as the craniocaudal view or mediolateral oblique view.
摘要翻译：一种乳腺癌筛查系统，其具有扫描沿着超声波吸收板（206）变平的乳房（204）的超声波探头（202）。所述超声探头（202）从乳房（204）体积中的连续平面拍摄超声图像，其大体平行于乳房（204）的预定x射线乳房X线照片视图的平面。优选地，超声图像切片显示在x射线乳房X线照相视图本身的显示器（406）附近，使得筛选放射科医师可以选择与X射线乳腺X线照片视图同时观看超声图像切片。优选地，预定x射线乳房X线照相视图是标准化的X射线乳房X线照片视图，例如头颈视图或中侧视图。

6. 发明申请

WO0241752A3 METHOD AND SYSTEM FOR INSTANT BIOPSY SPECIMEN ANALYSIS 审中-公开
标题翻译：用于生物样本分析的方法和系统
公开(公告)号：WO0241752A3
公开(公告)日：2003-08-14
申请号：PCT/US0143244
申请日：2001-11-20
申请人： U SYSTEMS INC , WANG SHIH-PING , CUPPLES TOMMY EARL , CHENG XIANGYONG
发明人： WANG SHIH-PING , CUPPLES TOMMY EARL , CHENG XIANGYONG
IPC分类号： A61B8/08 , A61B10/00 , A61B19/00 , G01N29/06 , G01N29/22 , G01N29/28 , G01S7/52 , G01S15/89 , A61B8/00
CPC分类号： G01S15/8993 , A61B8/0833 , A61B10/0096 , A61B2090/378 , G01N29/0609 , G01N29/223 , G01N29/28 , G01N2291/02466 , G01S7/52017
摘要： According to a preferred embodiment, a specimen 102 containing the tumor is extracted from the patient and suspended in a container 108 holding an acoustically conductive fluid. An ultrasound probe is brought into acoustic communication with the fluid and scan the specimen 108, preferably at an acoustic power setting higher than a maximum ultrasonic power permitted on live human tissue. The resulting two-dimensional or three dimensional ultrasound images of the specimen, which have a higher quality due to the increased acoustic power of the sc, are viewed on an output display for examining whether any portion of the tumor comes into contact with surfaace of the specimen. Preferably, the ultrasound images are segmented and processed by the ultrasound system in a manner that further assists in the determination of whether the specimen contains the entire tumor.
摘要翻译：根据优选实施例，从患者中提取含有肿瘤的标本102并悬浮在保持声导电液体的容器108中。使超声波探头与流体进行声学连通并扫描样本108，优选地在高于活人体组织上允许的最大超声功率的声功率设定。在输出显示器上观察由于sc增加的声功率而具有较高质量的所得到的样本的二维或三维超声图像，用于检查肿瘤的任何部分是否与标本。优选地，超声图像被分段和超声系统处理，以进一步有助于确定样本是否包含整个肿瘤的方式。

7. 发明申请

WO2014194069A2 RESISTIVE RANDOM-ACCESS MEMORY FORMED WITHOUT FORMING VOLTAGE 审中-公开
标题翻译：无电压形成的电阻随机存取存储器
公开(公告)号：WO2014194069A2
公开(公告)日：2014-12-04
申请号：PCT/US2014039990
申请日：2014-05-29
申请人： WANG SHIH-YUAN , WANG SHIH-PING
发明人： WANG SHIH-YUAN , WANG SHIH-PING
IPC分类号： G11C11/02
CPC分类号： H01L45/08 , G11C13/0004 , G11C13/0007 , G11C2213/15 , G11C2213/18 , G11C2213/51 , G11C2213/56 , G11C2213/77 , H01L27/2481 , H01L45/1226 , H01L45/1233 , H01L45/124 , H01L45/146 , H01L45/165 , H01L45/1683
摘要： Enhanced ion/vacancy mobility channels are descnbed for the resistive random access memory, memristor and phase change memory. Such channels provide more definitive conduction path than the more random conductive paths resulting from applied forming voltages.
摘要翻译：阻性随机存取存储器，忆阻器和相变存储器描述了增强的离子/空位迁移率通道。这样的通道提供比由施加的成形电压产生的更随机的导电路径更确定的传导路径。

8. 发明申请

WO2012060932A3 METHOD AND APPARATUS FOR HYSTEROSCOPY AND ENDOMETRIAL BIOPSY 审中-公开
标题翻译：用于脑膜炎和子宫内膜生物学的方法和装置
公开(公告)号：WO2012060932A3
公开(公告)日：2013-09-19
申请号：PCT/US2011051982
申请日：2011-09-16
申请人： ENDOSEE CORP , OUYANG XIAOLONG , INDMAN PAUL D , DECKMAN ROBERT K , WANG SHIH-PING
发明人： OUYANG XIAOLONG , INDMAN PAUL D , DECKMAN ROBERT K , WANG SHIH-PING
IPC分类号： A61B17/00
CPC分类号： A61B1/303 , A61B1/00052 , A61B1/00087 , A61B1/00094 , A61B1/00103 , A61B1/00105 , A61B1/00108 , A61B1/00124 , A61B1/00135 , A61B1/00154 , A61B1/015 , A61B1/018 , A61B10/0291 , A61B18/1485 , A61B90/361 , A61B90/37 , A61B2017/4216 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00559 , A61B2018/00577 , A61B2018/0212 , A61B2018/044 , A61B2090/306 , A61B2090/309 , A61B2090/372 , A61M1/0058 , A61M2210/1433
摘要： Methods and devices are described for performing a combined hysteroscopy and endometrial sampling in a manner that requires only a single insertion of an elongate object through a cervical opening of a patient's uterus. The distal end of an elongate, hollow sampling sheath of an integrated medical device is inserted through the cervical opening and into the uterus. Fluid is infused through the hollow interior of a sampling sheath, and outward through a distal opening into the uterus. The uterus becomes distended by the positive fluid pressure, allowing visualization. The inside surface of the distended uterus is endoscopically viewed by manipulating the integrated medical device in a manner that directs an imaging module attached to the sampling sheath near the distal end to multiple viewing positions. The corresponding video images of the inside surface are viewed on an electronic display screen of the integrated medical device that is positioned near the proximal end of the sampling sheath. After the viewing, and before withdrawing the distal end of the sampling sheath from the uterus, suction is applied to the hollow interior of the sampling sheath, which causes the distending fluid in the uterus to flow back into the sampling sheath through the distal opening, which returns the uterus to a non-distended state. With the uterus in the non- distended state, suction is applied while the integrated medical device is manipulated within the uterus in a manner that causes a sample of endometrium to be sucked into the tubing. The sample of endometrium is severed by at least one sharp edge formed along the distal opening. The sample is thus trapped in the hollow interior of the sampling sheath. Methods and devices are also described for performing a combined hysteroscopy and endometrial ablation in a manner that requires only a single insertion of an elongate object through a cervical opening of a patient's uterus.
摘要翻译：描述了以仅需要通过患者子宫颈的开口单一插入细长物体的方式进行组合宫腔镜检查和子宫内膜取样的方法和装置。集成医疗装置的细长的中空采样鞘的远端插入通过子宫颈开口并进入子宫。流体通过采样鞘的中空内部注入，并通过远端开口进入子宫。子宫由于积极的液体压力而膨胀，从而可视化。扩张子宫的内表面通过以将远端附近的取样鞘的成像模块引导到多个观察位置的方式操纵集成医疗装置来内窥镜观察。在位于采样鞘的近端附近的集成医疗装置的电子显示屏上观察内表面的相应视频图像。在观察之后，并且在从子宫拔出取样鞘的远端之前，将吸力施加到采样鞘的中空内部，这使得子宫中的膨胀流体通过远端开口回流到采样鞘中，它将子宫返回到非扩张状态。当子宫处于非扩张状态时，在使整合的医疗装置在子宫内被操纵以使子宫内膜样品被吸入管道的方式施加抽吸。子宫内膜样本被沿着远端开口形成的至少一个锋利边缘切断。因此样品被捕获在采样鞘的中空内部。还描述了用于以仅需要通过患者子宫颈切口的细长物体的单次插入的方式进行组合宫腔镜检查和子宫内膜切除的方法和装置。

9. 发明申请

WO2012151073A3 METHOD AND APPARATUS FOR HYSTEROSCOPY AND ENDOMETRIAL BIOPSY 审中-公开
标题翻译：用于脑膜炎和子宫内膜生物学的方法和装置
公开(公告)号：WO2012151073A3
公开(公告)日：2012-12-27
申请号：PCT/US2012034698
申请日：2012-04-23
申请人： ENDOSEE CORP , OUYANG XIAOLONG , INDMAN PAUL D , DECKMAN ROBERT K , WANG SHIH-PING
发明人： OUYANG XIAOLONG , INDMAN PAUL D , DECKMAN ROBERT K , WANG SHIH-PING
IPC分类号： A61B1/045
CPC分类号： A61B1/00066 , A61B1/00016 , A61B1/00034 , A61B1/00039 , A61B1/0005 , A61B1/00052 , A61B1/00087 , A61B1/00091 , A61B1/00094 , A61B1/00101 , A61B1/00103 , A61B1/00105 , A61B1/00108 , A61B1/00124 , A61B1/00128 , A61B1/00179 , A61B1/015 , A61B1/018 , A61B1/045 , A61B1/05 , A61B1/053 , A61B1/0607 , A61B1/0676 , A61B1/0684 , A61B1/126 , A61B1/303 , A61B10/0275 , A61B10/0291 , A61B10/04 , A61B34/25 , A61B90/361 , A61B2017/00221 , A61B2090/309 , A61B2090/372 , A61M2210/1433
摘要： Methods and devices are described for performing a combined hysteroscopy and endometrial sampling. Techniques for improving visual images include forward facing fluid ports for clearing tissue debris and LED positioning and design. Manufacturability is improved through separately formed tip and shaft pieces. User interface features are described including user-friendly handle-mounted buttons as well the use of an interactive integrated touch screen display. The handle and display can be mated to a docking station for storage and recharging batteries.
摘要翻译：描述了用于进行组合宫腔镜检查和子宫内膜取样的方法和装置。用于改善视觉图像的技术包括用于清除组织碎片和LED定位和设计的前向流体端口。通过单独形成的尖端和轴件改善可制造性。描述用户界面功能，包括用户友好的手柄安装按钮以及使用交互式集成触摸屏显示。手柄和显示屏可以配合到对接站，以便储存和充电电池。

10. 发明申请

WO2015084681A3 AUTOMATED BREAST ULTRASOUND EQUIPMENT AND METHODS USING ENHANCED NAVIGATOR AIDS 审中-公开
标题翻译：自动乳房超声波设备和使用增强导航器艾滋病的方法
公开(公告)号：WO2015084681A3
公开(公告)日：2015-10-29
申请号：PCT/US2014067758
申请日：2014-11-26
申请人： QVIEW MEDICAL INC , ZHANG WEI , SCHEIDER ALEXANDER , WANG SHIH-PING , ROMSDAHL HARLAN , NEFF THOMAS
发明人： ZHANG WEI , SCHEIDER ALEXANDER , WANG SHIH-PING , ROMSDAHL HARLAN , NEFF THOMAS
IPC分类号： A61B8/00
CPC分类号： A61B8/085 , A61B8/0825 , A61B8/403 , A61B8/4405 , A61B8/5223
摘要： A method and system acquiring, processing and displaying breast ultrasound images in a way that makes breast ultrasound screening more practical and thus more widely used, and reduces the occurrence of missing cancers in screening and diagnosis, using automated scanning of chestwardly compressed breasts with ultrasound. Enhanced, whole-breast navigator overview images are produced from scanning breasts with ultrasound that emphasize abnormalities in the breast while excluding obscuring influences of non-breast structures, particularly those external to the breast such as ribs and chest wall, and differentiating between likely malignant and likely benign abnormalities and otherwise enhancing the navigator overview image and other images, thereby reducing the time to read, screen, and/or diagnose to practical time limits and also reduce screening or diagnostic errors.
摘要翻译：一种方法和系统采用乳房超声检查更加实用，因此更广泛使用的方式获取，处理和显示乳房超声图像，并通过使用超声波胸部压缩乳房进行自动扫描，减少筛查和诊断中遗漏的癌症的发生。增强的全乳头导航仪概述图像是通过扫描具有强调乳房异常的超声波的乳房产生的，同时排除非乳房结构的模糊影响，特别是胸部以外的肋骨和胸壁，以及可能的恶性和可能是良性异常，否则增强导航仪概览图像和其他图像，从而减少读取，屏幕和/或诊断到实际时间限制的时间，并且还减少筛查或诊断错误。

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