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1. 发明申请

WO2012148745A1 DISTAL BALLOON BOND FOR TEMPORARY SEALING LOCATION DEVICE AND METHODS 审中-公开
标题翻译：用于临时密封位置设备和方法的远程气球粘结
公开(公告)号：WO2012148745A1
公开(公告)日：2012-11-01
申请号：PCT/US2012/034004
申请日：2012-04-18
申请人： ST. JUDE MEDICAL PUERTO RICO LLC , TEGELS, Zachary J.
发明人： TEGELS, Zachary J.
IPC分类号： A61B17/00
CPC分类号： A61B17/0057 , A61B2017/00557 , A61B2017/0065 , A61B2017/00659 , A61B2017/00672 , A61B2017/22067
摘要： A vascular closure system (10) includes a dual lumen tube (14), an inflatable balloon (16), and a distal sealing assembly (18). The dual lumen tube includes a proximal end portion, a distal end portion, a first lumen, and a second lumen. The first lumen is coupled in fluid communication with an inflation fluid and has a first distal opening at a distal end of the dual lumen tube. The second lumen extends from the proximal end portion to the distal end portion. The inflatable balloon is mounted to the dual lumen tube in fluid communication with the first lumen, and is inflatable within a vessel to temporarily seal closed a tissue puncture. The distal sealing assembly includes a distal sealing member (74) positioned distal of the inflatable balloon, and is detachable from the distal sealing assembly at a location exterior and adjacent to the vessel.
摘要翻译：血管闭合系统（10）包括双腔管（14），可充气球囊（16）和远端密封组件（18）。双腔管包括近端部分，远端部分，第一内腔和第二管腔。第一管腔与膨胀流体流体连通地联接，并且在双腔管的远端具有第一远端开口。第二腔从近端部延伸到远端部。可膨胀气囊安装到与第一腔流体连通的双腔管，并且可在容器内充气以临时密封封闭组织穿刺。远侧密封组件包括位于可膨胀气囊远侧的远端密封构件（74），并且在远离密封组件的外部和邻近容器的位置处可拆卸。

2. 发明申请

WO2012170601A1 CIRCUMFERENTIALLY LOCATED SUTURE RELEASE MECHANISM FOR VASCULAR CLOSURE DEVICE 审中-公开
标题翻译：用于血管闭合装置的通用定位释放机构
公开(公告)号：WO2012170601A1
公开(公告)日：2012-12-13
申请号：PCT/US2012/041202
申请日：2012-06-07
申请人： ST. JUDE MEDICAL PUERTO RICO LLC , TEGELS, Zachary J.
发明人： TEGELS, Zachary J.
IPC分类号： A61B17/00
CPC分类号： A61B17/0057 , A61B17/0401 , A61B2017/00623 , A61B2017/00654 , A61B2017/0496
摘要： A tissue puncture closure device includes an anchor, a sealing plug, a filament, a compaction member assembly, a spool, a stop feature, a driving plate, and a release member. The filament attaches the sealing plug to the anchor. The compaction member assembly applies an axially directed compressive force to compact the sealing plug toward the anchor. The spool has a portion of the filament wound thereon. The stop feature is coupled to the spool. The driving plate is connected to the spool and arranged to apply a force to a proximal end of the compaction member assembly upon rotation of the driving plate to advance the compaction member assembly. The release member is operable from a first position contacting the stop feature to limit rotation of the spool, and a second position out of contact with the stop feature to permit rotation of the spool.
摘要翻译：组织穿刺闭合装置包括锚固件，密封塞，细丝，压实构件组件，线轴，止动构件，驱动板和释放构件。灯丝将密封塞连接到锚杆上。压紧构件组件施加轴向定向的压缩力以将密封塞压向锚固件。卷轴具有缠绕在其上的细丝的一部分。停止功能耦合到线轴。所述驱动板连接到所述线轴，并且布置成在所述驱动板旋转时向所述压实构件组件的近端施加力以推进所述压实构件组件。释放构件可从接触止动特征的第一位置操作以限制线轴的旋转，以及与止动构件脱离接触以允许线轴旋转的第二位置。

3. 发明申请

WO2012047264A1 CAM DRIVEN COMPACTION TUBE FOR VASCULAR CLOSURE DEVICE 审中-公开
标题翻译：用于血管闭合装置的CAM驱动压力管
公开(公告)号：WO2012047264A1
公开(公告)日：2012-04-12
申请号：PCT/US2011/001660
申请日：2011-09-27
申请人： ST. JUDE MEDICAL PUERTO RICO LLC , TEGELS, Zachary J.
发明人： TEGELS, Zachary J.
IPC分类号： A61B17/00 , A61B17/04
CPC分类号： A61B17/0057 , A61B17/0482 , A61B17/06123 , A61B2017/00637 , A61B2017/00654 , A61B2017/00659 , A61B2017/0414 , A61B2017/0417 , A61B2017/0496 , A61B2017/2915
摘要： A method and apparatus (200) for sealing a puncture or incision formed percutaneously in a tissue. The apparatus including an anchor (208), a sealing plug (210), a filament (204) connected between the sealing plug and the anchor, a compaction member assembly (e.g. 212), a spool (266) and a driving plate (264). The compaction member assembly being disposed adjacent the sealing plug and structured and arranged to apply an axially directed compressive force to automatically compact the sealing plug toward the anchor. The spool has a portion of the filament wound thereon. The driving plate being connected to the spool and having a cam surface portion. The cam surface portion is arranged to contact a proximal end of the compaction member assembly upon rotation of the spool to advance a distal end of the compaction member assembly.
摘要翻译：一种用于密封在组织中经皮穿刺的穿刺或切口的方法和装置（200）。该装置包括锚固件（208），密封塞（210），连接在密封塞和锚固件之间的细丝（204），压实构件组件（例如212），阀芯（266）和驱动板）。所述压实构件组件邻近所述密封塞设置并构造并布置成施加轴向定向的压缩力以自动地将所述密封塞压紧到所述锚固件。卷轴具有缠绕在其上的细丝的一部分。驱动板连接到卷轴并具有凸轮表面部分。凸轮表面部分布置成在卷轴旋转时接触压实构件组件的近端，以推动压实构件组件的远端。

4. 发明申请

WO2012158931A1 PROCEDURAL SHEATH ADAPTER FOR VASCULAR CLOSURE DEVICE 审中-公开
标题翻译：用于血管闭合装置的程序适应器
公开(公告)号：WO2012158931A1
公开(公告)日：2012-11-22
申请号：PCT/US2012/038370
申请日：2012-05-17
申请人： ST. JUDE MEDICAL PUERTO RICO LLC , TEGELS, Zachary J. , EBELING, Philip J.
发明人： TEGELS, Zachary J. , EBELING, Philip J.
IPC分类号： A61B17/00
CPC分类号： A61B17/0057 , A61B2017/00623 , A61B2017/00659
摘要： A tissue puncture closure device includes an anchor, a sealing plug, a compaction member, a suture, a handle portion, a sheath attachment member, and a sheath adapter. The compaction member is configured to compress the sealing plug towards the anchor. The suture is coupled to the sealing plug and anchored. The handle portion is arranged proximal of the sealing plug and anchor. The sheath attachment member extends from the handle portion. The sheath adapter has a first end portion configured to mount to the sheath attachment member, and a second end portion configured to mount to a procedural sheath that is inserted into a tissue puncture.
摘要翻译：组织穿刺闭合装置包括锚固件，密封塞，压实构件，缝合线，手柄部分，护套附接构件和护套适配器。压实构件构造成朝向锚固体压缩密封塞。缝合线连接到密封塞并锚定。手柄部分布置在密封塞和锚固件的近侧。护套安装构件从手柄部分延伸。护套适配器具有构造成安装到护套附接构件的第一端部部分，以及构造成安装到插入到组织穿刺中的手术护套的第二端部部分。

5. 发明申请

WO2014107179A1 VASCULAR CLOSURE DEVICE WITH IMPROVED SIDE LOADING 审中-公开
标题翻译：具有改进的侧面装载的血管闭合装置
公开(公告)号：WO2014107179A1
公开(公告)日：2014-07-10
申请号：PCT/US2013/029239
申请日：2013-03-06
申请人： ST. JUDE MEDICAL PUERTO RICO LLC
发明人： TEGELS, Zachary J.
IPC分类号： A61B17/00
CPC分类号： A61B17/0057 , A61B2017/00623 , A61B2017/00654 , A61B2017/00898
摘要： A tissue puncture closure device includes a vessel locator (14) and a sealing plug delivery member (12). The vessel locator includes an expandable member (54). The sealing plug delivery member includes a carrier tube (16), a sealing plug (18), and a locking member (38). The carrier tube includes a distal end and a side opening (34), the side opening extending proximally from the distal end along at least a portion of a length of the carrier tube to provide lateral insertion of the vessel locator into an interior of the carrier tube. The sealing plug includes a lumen (46) and a slot (44) extending from a distal end to a proximal end of the sealing plug, wherein the slot provides lateral access of the vessel locator into the lumen. The locking member is operable to retain the vessel locator within the sealing plug delivery member.
摘要翻译：组织穿刺闭合装置包括容器定位器（14）和密封塞输送构件（12）。容器定位器包括可扩张构件（54）。密封塞输送构件包括载体管（16），密封塞（18）和锁定构件（38）。载体管包括远端和侧开口（34），所述侧开口沿着所述载体管的长度的至少一部分从所述远端向近侧延伸，以将所述容器定位器侧向插入所述载体的内部管。密封塞包括从密封塞的远端延伸到近端的内腔（46）和狭槽（44），其中所述狭槽提供血管定位器进入内腔的侧向进入。锁定构件可操作以将容器定位器保持在密封塞输送构件内。

6. 发明申请

WO2013115993A1 BALLOON LOCATION DEVICE MANIFOLD FOR VASCULAR CLOSURE DEVICE 审中-公开
标题翻译：用于血管闭合装置的气囊位置装置歧管
公开(公告)号：WO2013115993A1
公开(公告)日：2013-08-08
申请号：PCT/US2013/021806
申请日：2013-01-17
申请人： ST. JUDE MEDICAL PUERTO RICO LLC
发明人： TEGELS, Zachary J. , VIDLUND, Robert M.
IPC分类号： A61B17/00
CPC分类号： A61B17/0057 , A61B2017/00597 , A61B2017/00623 , A61B2017/00654 , A61B2090/064 , A61B2090/0811
摘要： A vessel puncture closure device includes a housing, an inflation tube, a balloon member, an indicator member, and a delivery tube. The inflation tube defines an inflation lumen and extends from the housing. The balloon member is positioned at a distal end of the inflation tube and is arranged in fluid communication with the inflation lumen. The indicator member is positioned in and movable relative to the housing in response to a pressure condition in the balloon member. The delivery tube is connected to the indicator member and balloon member, and extends through the housing and inflation tube.
摘要翻译：容器穿刺闭合装置包括壳体，充气管，球囊构件，指示器构件和输送管。充气管限定充气腔并从壳体延伸。气囊构件位于充气管的远端并且布置成与充气腔流体连通。响应于球囊构件中的压力状态，指示器构件相对于壳体定位并且可移动。输送管连接到指示器构件和气囊构件，并且延伸穿过壳体和充气管。

7. 发明申请

WO2013112343A1 PROCEDURAL SHEATH SECUREMENT DEVICE 审中-公开
标题翻译：程序保护装置
公开(公告)号：WO2013112343A1
公开(公告)日：2013-08-01
申请号：PCT/US2013/021813
申请日：2013-01-17
申请人： ST. JUDE MEDICAL PUERTO RICO LLC
发明人： VIDLUND, Robert M. , TEGELS, Zachary J. , ESCOBAR, Martha , TERWEY, Russell D. , KILLION, Douglas P.
IPC分类号： A61B17/34
CPC分类号： A61B17/0057 , A61B17/3415 , A61B90/11 , A61B2017/00654 , A61B2017/3407 , A61B2017/347
摘要： A procedural sheath holding device includes a base member and a securing member. The base member is positionable in contact with an outer skin surface adjacent to an incision. The securing member is attached to the base member and includes a securing portion operable to releasably secure a procedural sheath in a fixed axial position relative to the skin surface when a vascular closure device is inserted through the procedural sheath to seal the incision. The securing member may be pivotal relative to the base member.
摘要翻译：手术护套保持装置包括基部构件和固定构件。基部构件可定位成与切口相邻的外皮表面接触。固定构件附接到基部构件并且包括固定部分，当将血管闭合装置插入穿过手术鞘以密封切口时，固定部分可操作以将手术护套可释放地固定在相对于皮肤表面的固定的轴向位置。固定构件可以相对于基座构件枢转。

8. 发明申请

WO2014031258A1 FLEXIBLE TAMPING MEMBER 审中-公开
标题翻译：灵活的冲压件
公开(公告)号：WO2014031258A1
公开(公告)日：2014-02-27
申请号：PCT/US2013/051039
申请日：2013-07-18
申请人： ST. JUDE MEDICAL PUERTO RICO LLC
发明人： TEGELS, Zachary J. , STEVEN, Willard , TERWEY, Russell D. , WHITE, Troy T.
IPC分类号： A61B17/00 , A61B19/00
CPC分类号： A61B17/0057 , A61B90/03 , A61B2017/00637 , A61B2017/00654 , A61B2017/00858 , A61B2017/00991 , A61B2090/032
摘要： Methods and apparatus are disclosed for sealing a puncture or incision formed percutaneously in tissue separating two internal portions of the body of a living being with an anchor (506), a sealing plug (510) and a filament (104,502) connecting the anchor and sealing plug. The methods and apparatus provide for a compaction device or a tamping device (200,300,400,600,700,800,900,1000) that improves control of the amount of force exerted upon the sealing plug. Further, the compaction tube or tamping device can deform upon application of excessive compaction force, thereby reducing the possibility of damage to the sealing plug, anchor, or artery.
摘要翻译：公开了用于密封经皮形成的穿刺或切口的组织，所述组织用锚固件（506），密封塞（510）和连接锚固件和密封件的长丝（104,502）分离生物体的两个内部部分插头。所述方法和设备提供了压实装置或捣固装置（200,300,400,600,700,800,900,1000），其改善了施加在密封塞上的力的控制。此外，当施加过度的压实力时，压实管或捣固装置可能变形，从而减少损坏密封塞，锚或动脉的可能性。

9. 发明申请

WO2010017313A1 STENT EDGE PROTECTION AND METHODS 审中-公开
标题翻译： STENT边缘保护和方法
公开(公告)号：WO2010017313A1
公开(公告)日：2010-02-11
申请号：PCT/US2009/052881
申请日：2009-08-05
申请人： BOSTON SCIENTIFIC SCIMED, INC. , BRONSON, Mary , GRABOWSKI, Gerald , MALEWICZ, Andrzej , PRINDLE, Katherine , TEGELS, Zachary J. , TURNER, Karen
发明人： BRONSON, Mary , GRABOWSKI, Gerald , MALEWICZ, Andrzej , PRINDLE, Katherine , TEGELS, Zachary J. , TURNER, Karen
IPC分类号： A61F2/84
CPC分类号： A61F2/954 , A61F2/856 , A61F2/91 , A61F2/958 , A61F2230/001
摘要： A catheter assembly and related methods directed to stent edge protection for an edge of a stent. One example stent edge protect member (20) is positioned with a distal end portion (60) of the stent edge protect member arranged proximal of and adjacent to a proximal end (50) of the stent (16). The stent edge protect member defines an outer surface that transitions from an outer surface of the stent at the proximal end of the stent to an outer surface of the catheter branch (14) on which the stent edge protect member is positioned. The stent edge protect member can be positioned on a single catheter branch or multiple catheter branches.
摘要翻译：导管组件和针对支架边缘的支架边缘保护的相关方法。一个示例性支架边缘保护构件（20）定位成使得支架边缘保护构件的远端部分（60）布置在支架（16）的近端（50）的近侧并且邻近支架的近端（50）。支架边缘保护构件限定外表面，该外表面在支架近端处的支架的外表面转移到支架边缘保护构件所在的导管支路（14）的外表面。支架边缘保护构件可以位于单个导管分支或多个导管分支上。

10. 发明申请

WO2016168609A1 APPARATUS AND METHODS FOR DELIVERY, REPOSITIONING, AND RETRIEVAL OF TRANSCATHETER PROSTHETIC VALVES 审中-公开
标题翻译：交通运输预报阀的交付，报告和检索的装置和方法
公开(公告)号：WO2016168609A1
公开(公告)日：2016-10-20
申请号：PCT/US2016/027770
申请日：2016-04-15
申请人： TENDYNE HOLDINGS, INC. , EKVALL, Craig A. , LE, Khoi , OTTE, John F. , TEGELS, Zachary J. , VIDLUND, Robert M.
发明人： EKVALL, Craig A. , LE, Khoi , OTTE, John F. , TEGELS, Zachary J. , VIDLUND, Robert M.
IPC分类号： A61F2/24
CPC分类号： A61F2/2433 , A61B2017/00292 , A61F2/2412 , A61F2/2418 , A61F2/2436 , A61F2/2439 , A61F2/2466 , A61F2002/9517 , A61F2002/9522 , A61F2220/0016 , A61F2230/0023 , A61F2230/005 , A61F2250/0039 , A61M25/0102 , A61M2025/0681
摘要： Apparatus and methods are described herein for use in the delivery and deployment of a prosthetic mitral valve into a heart. In some embodiments, an apparatus includes a catheter assembly, a valve holding tube and a handle assembly. The valve holding tube is releasably couplable to a proximal end portion of the catheter assembly and to a distal end portion of the handle assembly. The handle assembly includes a housing and a delivery rod. The delivery rod is configured to be actuated to move distally relative to the housing to move a prosthetic heart valve disposed within the valve holding tube out of the valve holding tube and distally within a lumen of the elongate sheath of the catheter assembly. The catheter assembly is configured to be actuated to move proximally relative to the housing such that the prosthetic valve is disposed outside of the lumen of the elongate sheath.
摘要翻译：本文描述的装置和方法用于将二次瓣膜递送和部署到心脏中。在一些实施例中，装置包括导管组件，阀保持管和手柄组件。阀保持管可释放地联接到导管组件的近端部分和手柄组件的远端部分。手柄组件包括壳体和输送杆。输送杆构造成被致动以相对于壳体向远侧移动，以将设置在瓣膜保持管内的假体心脏瓣膜移出阀保持管并远离地在导管组件的细长护套的内腔内。导管组件构造成被致动以相对于壳体向近侧移动，使得假体瓣膜设置在细长护套的内腔的外侧。

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