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1. 发明申请

WO2010017313A1 STENT EDGE PROTECTION AND METHODS 审中-公开
标题翻译： STENT边缘保护和方法
公开(公告)号：WO2010017313A1
公开(公告)日：2010-02-11
申请号：PCT/US2009/052881
申请日：2009-08-05
申请人： BOSTON SCIENTIFIC SCIMED, INC. , BRONSON, Mary , GRABOWSKI, Gerald , MALEWICZ, Andrzej , PRINDLE, Katherine , TEGELS, Zachary J. , TURNER, Karen
发明人： BRONSON, Mary , GRABOWSKI, Gerald , MALEWICZ, Andrzej , PRINDLE, Katherine , TEGELS, Zachary J. , TURNER, Karen
IPC分类号： A61F2/84
CPC分类号： A61F2/954 , A61F2/856 , A61F2/91 , A61F2/958 , A61F2230/001
摘要： A catheter assembly and related methods directed to stent edge protection for an edge of a stent. One example stent edge protect member (20) is positioned with a distal end portion (60) of the stent edge protect member arranged proximal of and adjacent to a proximal end (50) of the stent (16). The stent edge protect member defines an outer surface that transitions from an outer surface of the stent at the proximal end of the stent to an outer surface of the catheter branch (14) on which the stent edge protect member is positioned. The stent edge protect member can be positioned on a single catheter branch or multiple catheter branches.
摘要翻译：导管组件和针对支架边缘的支架边缘保护的相关方法。一个示例性支架边缘保护构件（20）定位成使得支架边缘保护构件的远端部分（60）布置在支架（16）的近端（50）的近侧并且邻近支架的近端（50）。支架边缘保护构件限定外表面，该外表面在支架近端处的支架的外表面转移到支架边缘保护构件所在的导管支路（14）的外表面。支架边缘保护构件可以位于单个导管分支或多个导管分支上。

2. 发明申请

WO2012170601A1 CIRCUMFERENTIALLY LOCATED SUTURE RELEASE MECHANISM FOR VASCULAR CLOSURE DEVICE 审中-公开
标题翻译：用于血管闭合装置的通用定位释放机构
公开(公告)号：WO2012170601A1
公开(公告)日：2012-12-13
申请号：PCT/US2012/041202
申请日：2012-06-07
申请人： ST. JUDE MEDICAL PUERTO RICO LLC , TEGELS, Zachary J.
发明人： TEGELS, Zachary J.
IPC分类号： A61B17/00
CPC分类号： A61B17/0057 , A61B17/0401 , A61B2017/00623 , A61B2017/00654 , A61B2017/0496
摘要： A tissue puncture closure device includes an anchor, a sealing plug, a filament, a compaction member assembly, a spool, a stop feature, a driving plate, and a release member. The filament attaches the sealing plug to the anchor. The compaction member assembly applies an axially directed compressive force to compact the sealing plug toward the anchor. The spool has a portion of the filament wound thereon. The stop feature is coupled to the spool. The driving plate is connected to the spool and arranged to apply a force to a proximal end of the compaction member assembly upon rotation of the driving plate to advance the compaction member assembly. The release member is operable from a first position contacting the stop feature to limit rotation of the spool, and a second position out of contact with the stop feature to permit rotation of the spool.
摘要翻译：组织穿刺闭合装置包括锚固件，密封塞，细丝，压实构件组件，线轴，止动构件，驱动板和释放构件。灯丝将密封塞连接到锚杆上。压紧构件组件施加轴向定向的压缩力以将密封塞压向锚固件。卷轴具有缠绕在其上的细丝的一部分。停止功能耦合到线轴。所述驱动板连接到所述线轴，并且布置成在所述驱动板旋转时向所述压实构件组件的近端施加力以推进所述压实构件组件。释放构件可从接触止动特征的第一位置操作以限制线轴的旋转，以及与止动构件脱离接触以允许线轴旋转的第二位置。

3. 发明申请

WO2016168609A1 APPARATUS AND METHODS FOR DELIVERY, REPOSITIONING, AND RETRIEVAL OF TRANSCATHETER PROSTHETIC VALVES 审中-公开
标题翻译：交通运输预报阀的交付，报告和检索的装置和方法
公开(公告)号：WO2016168609A1
公开(公告)日：2016-10-20
申请号：PCT/US2016/027770
申请日：2016-04-15
申请人： TENDYNE HOLDINGS, INC. , EKVALL, Craig A. , LE, Khoi , OTTE, John F. , TEGELS, Zachary J. , VIDLUND, Robert M.
发明人： EKVALL, Craig A. , LE, Khoi , OTTE, John F. , TEGELS, Zachary J. , VIDLUND, Robert M.
IPC分类号： A61F2/24
CPC分类号： A61F2/2433 , A61B2017/00292 , A61F2/2412 , A61F2/2418 , A61F2/2436 , A61F2/2439 , A61F2/2466 , A61F2002/9517 , A61F2002/9522 , A61F2220/0016 , A61F2230/0023 , A61F2230/005 , A61F2250/0039 , A61M25/0102 , A61M2025/0681
摘要： Apparatus and methods are described herein for use in the delivery and deployment of a prosthetic mitral valve into a heart. In some embodiments, an apparatus includes a catheter assembly, a valve holding tube and a handle assembly. The valve holding tube is releasably couplable to a proximal end portion of the catheter assembly and to a distal end portion of the handle assembly. The handle assembly includes a housing and a delivery rod. The delivery rod is configured to be actuated to move distally relative to the housing to move a prosthetic heart valve disposed within the valve holding tube out of the valve holding tube and distally within a lumen of the elongate sheath of the catheter assembly. The catheter assembly is configured to be actuated to move proximally relative to the housing such that the prosthetic valve is disposed outside of the lumen of the elongate sheath.
摘要翻译：本文描述的装置和方法用于将二次瓣膜递送和部署到心脏中。在一些实施例中，装置包括导管组件，阀保持管和手柄组件。阀保持管可释放地联接到导管组件的近端部分和手柄组件的远端部分。手柄组件包括壳体和输送杆。输送杆构造成被致动以相对于壳体向远侧移动，以将设置在瓣膜保持管内的假体心脏瓣膜移出阀保持管并远离地在导管组件的细长护套的内腔内。导管组件构造成被致动以相对于壳体向近侧移动，使得假体瓣膜设置在细长护套的内腔的外侧。

4. 发明申请

WO2012148745A1 DISTAL BALLOON BOND FOR TEMPORARY SEALING LOCATION DEVICE AND METHODS 审中-公开
标题翻译：用于临时密封位置设备和方法的远程气球粘结
公开(公告)号：WO2012148745A1
公开(公告)日：2012-11-01
申请号：PCT/US2012/034004
申请日：2012-04-18
申请人： ST. JUDE MEDICAL PUERTO RICO LLC , TEGELS, Zachary J.
发明人： TEGELS, Zachary J.
IPC分类号： A61B17/00
CPC分类号： A61B17/0057 , A61B2017/00557 , A61B2017/0065 , A61B2017/00659 , A61B2017/00672 , A61B2017/22067
摘要： A vascular closure system (10) includes a dual lumen tube (14), an inflatable balloon (16), and a distal sealing assembly (18). The dual lumen tube includes a proximal end portion, a distal end portion, a first lumen, and a second lumen. The first lumen is coupled in fluid communication with an inflation fluid and has a first distal opening at a distal end of the dual lumen tube. The second lumen extends from the proximal end portion to the distal end portion. The inflatable balloon is mounted to the dual lumen tube in fluid communication with the first lumen, and is inflatable within a vessel to temporarily seal closed a tissue puncture. The distal sealing assembly includes a distal sealing member (74) positioned distal of the inflatable balloon, and is detachable from the distal sealing assembly at a location exterior and adjacent to the vessel.
摘要翻译：血管闭合系统（10）包括双腔管（14），可充气球囊（16）和远端密封组件（18）。双腔管包括近端部分，远端部分，第一内腔和第二管腔。第一管腔与膨胀流体流体连通地联接，并且在双腔管的远端具有第一远端开口。第二腔从近端部延伸到远端部。可膨胀气囊安装到与第一腔流体连通的双腔管，并且可在容器内充气以临时密封封闭组织穿刺。远侧密封组件包括位于可膨胀气囊远侧的远端密封构件（74），并且在远离密封组件的外部和邻近容器的位置处可拆卸。

5. 发明申请

WO2018005779A1 PROSTHETIC HEART VALVES AND APPARATUS AND METHODS FOR DELIVERY OF SAME 审中-公开
标题翻译：人造心脏瓣膜和装置及其递送方法
公开(公告)号：WO2018005779A1
公开(公告)日：2018-01-04
申请号：PCT/US2017/039972
申请日：2017-06-29
申请人： TEGELS, Zachary J. , VIDLUND, Zach , VIDLUND, Robert M.
发明人： TEGELS, Zachary J. , VIDLUND, Zach , VIDLUND, Robert M.
IPC分类号： A61F2/24
摘要： Apparatus and methods are described herein for various embodiments of a prosthetic heart valve, delivery apparatus and delivery methods for delivering a prosthetic heart valve to a heart of a patient via a transapical or transvascular delivery approach. In some embodiments, a prosthetic heart valve includes an outer frame coupled to an inner frame and the outer frame is movable between a first configuration relative to the inner frame and a second inverted configuration relative to the inner frame. The valve can be delivered to a heart using an apparatus that includes a delivery sheath that defines a lumen that can receive the prosthetic heart valve therein when the outer frame is in the inverted configuration. Actuation wires are releasably coupled to the outer frame and can be used to help revert the outer frame after the valve is deployed outside of the delivery sheath and within the heart.
摘要翻译：这里描述了用于假体心脏瓣膜的各种实施例的装置和方法，递送装置和递送方法，用于经由经心尖或经血管递送方法将人造心脏瓣膜递送到患者的心脏。在一些实施例中，人造心脏瓣膜包括耦合到内部框架的外部框架，并且外部框架可相对于内部框架在第一构造和相对于内部框架的第二颠倒构造之间移动。使用包括输送护套的装置可以将瓣膜输送到心脏，所述输送护套限定当外框架处于倒置构造时可以将人造心脏瓣膜容纳在其中的管腔。驱动线可释放地连接到外部框架，并且可以用于在瓣膜部署在输送护套外部并且在心脏内部之后帮助恢复外部框架。

6. 发明申请

WO2012158931A1 PROCEDURAL SHEATH ADAPTER FOR VASCULAR CLOSURE DEVICE 审中-公开
标题翻译：用于血管闭合装置的程序适应器
公开(公告)号：WO2012158931A1
公开(公告)日：2012-11-22
申请号：PCT/US2012/038370
申请日：2012-05-17
申请人： ST. JUDE MEDICAL PUERTO RICO LLC , TEGELS, Zachary J. , EBELING, Philip J.
发明人： TEGELS, Zachary J. , EBELING, Philip J.
IPC分类号： A61B17/00
CPC分类号： A61B17/0057 , A61B2017/00623 , A61B2017/00659
摘要： A tissue puncture closure device includes an anchor, a sealing plug, a compaction member, a suture, a handle portion, a sheath attachment member, and a sheath adapter. The compaction member is configured to compress the sealing plug towards the anchor. The suture is coupled to the sealing plug and anchored. The handle portion is arranged proximal of the sealing plug and anchor. The sheath attachment member extends from the handle portion. The sheath adapter has a first end portion configured to mount to the sheath attachment member, and a second end portion configured to mount to a procedural sheath that is inserted into a tissue puncture.
摘要翻译：组织穿刺闭合装置包括锚固件，密封塞，压实构件，缝合线，手柄部分，护套附接构件和护套适配器。压实构件构造成朝向锚固体压缩密封塞。缝合线连接到密封塞并锚定。手柄部分布置在密封塞和锚固件的近侧。护套安装构件从手柄部分延伸。护套适配器具有构造成安装到护套附接构件的第一端部部分，以及构造成安装到插入到组织穿刺中的手术护套的第二端部部分。

7. 发明申请

WO2016126942A2 EXPANDABLE EPICARDIAL PADS AND DEVICES AND METHODS FOR DELIVERY OF SAME 审中-公开
标题翻译：可扩展的EPICARDIAL PADS和装置及其传送方法
公开(公告)号：WO2016126942A2
公开(公告)日：2016-08-11
申请号：PCT/US2016/016567
申请日：2016-02-04
申请人： VIDLUND, Robert M. , KOVALSKY, Igor , TEGELS, Zachary J. , EKVALL, Craig A.
发明人： VIDLUND, Robert M. , KOVALSKY, Igor , TEGELS, Zachary J. , EKVALL, Craig A.
IPC分类号： A61F2/24 , A61B17/04
CPC分类号： A61F2/2418 , A61B17/0401 , A61B2017/0443 , A61B2017/3425 , A61F2/2433 , A61F2/2436 , A61F2/2439 , A61F2/2457 , A61F2220/0016 , A61F2220/0041 , A61F2220/0075 , A61F2220/0083 , A61F2230/0093 , A61F2250/0039 , A61F2250/0063 , A61F2250/0098
摘要： Apparatus and methods are described herein for use in the delivery of a prosthetic mitral valve. In some embodiments, a method includes after deploying a prosthetic mitral valve within a mitral annulus of a heart, inserting a delivery sheath into the patients body and disposing a distal end near the apex of the heart. A tissue dilator device can be inserted through a lumen of the delivery sheath and used to dilate tissue near the apex of the heart to create space for an epicardial pad device. After dilating the tissue, the tissue dilator device can be removed and an epicardial pad device can be attached to a tether extending from the prosthetic valve. The pad can be secured at the apex of the heart to secure the prosthetic valve and tether in a desired position. In some embodiments, the epicardial pad device can be an expandable epicardial pad device.
摘要翻译：本文描述了用于递送假性二尖瓣的装置和方法。在一些实施例中，一种方法包括在将心脏的二尖瓣环内部署假体二尖瓣之后，将输送护套插入患者体内并将远端设置在心脏顶点附近。组织扩张器装置可插入穿过输送护套的内腔，并用于扩张心脏顶点附近的组织以产生心外膜垫装置的空间。在扩张组织之后，可以去除组织扩张器装置，并且将心外膜垫装置连接到从假肢瓣延伸的系绳。垫可以固定在心脏的顶点以将假体瓣膜和系绳固定在期望的位置。在一些实施例中，心外膜垫装置可以是可扩张心外膜垫装置。

8. 发明申请

WO2012047264A1 CAM DRIVEN COMPACTION TUBE FOR VASCULAR CLOSURE DEVICE 审中-公开
标题翻译：用于血管闭合装置的CAM驱动压力管
公开(公告)号：WO2012047264A1
公开(公告)日：2012-04-12
申请号：PCT/US2011/001660
申请日：2011-09-27
申请人： ST. JUDE MEDICAL PUERTO RICO LLC , TEGELS, Zachary J.
发明人： TEGELS, Zachary J.
IPC分类号： A61B17/00 , A61B17/04
CPC分类号： A61B17/0057 , A61B17/0482 , A61B17/06123 , A61B2017/00637 , A61B2017/00654 , A61B2017/00659 , A61B2017/0414 , A61B2017/0417 , A61B2017/0496 , A61B2017/2915
摘要： A method and apparatus (200) for sealing a puncture or incision formed percutaneously in a tissue. The apparatus including an anchor (208), a sealing plug (210), a filament (204) connected between the sealing plug and the anchor, a compaction member assembly (e.g. 212), a spool (266) and a driving plate (264). The compaction member assembly being disposed adjacent the sealing plug and structured and arranged to apply an axially directed compressive force to automatically compact the sealing plug toward the anchor. The spool has a portion of the filament wound thereon. The driving plate being connected to the spool and having a cam surface portion. The cam surface portion is arranged to contact a proximal end of the compaction member assembly upon rotation of the spool to advance a distal end of the compaction member assembly.
摘要翻译：一种用于密封在组织中经皮穿刺的穿刺或切口的方法和装置（200）。该装置包括锚固件（208），密封塞（210），连接在密封塞和锚固件之间的细丝（204），压实构件组件（例如212），阀芯（266）和驱动板）。所述压实构件组件邻近所述密封塞设置并构造并布置成施加轴向定向的压缩力以自动地将所述密封塞压紧到所述锚固件。卷轴具有缠绕在其上的细丝的一部分。驱动板连接到卷轴并具有凸轮表面部分。凸轮表面部分布置成在卷轴旋转时接触压实构件组件的近端，以推动压实构件组件的远端。

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